Busch Lab

ZMP

ak4

Ensembl ID:
ENSDARG00000006546
ZFIN ID:
ZDB-GENE-040426-2505
Description:
adenylate kinase isoenzyme 4, mitochondrial [Source:RefSeq peptide;Acc:NP_998464]
Human Orthologue:
AK4
Human Description:
adenylate kinase 4 [Source:HGNC Symbol;Acc:363]
Mouse Orthologue:
Ak4
Mouse Description:
adenylate kinase 4 Gene [Source:MGI Symbol;Acc:MGI:87979]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa33886 Essential Splice Site, Splice Site Available for shipment Available now
sa2314 Nonsense F2 line generated Not yet available

Mutation Details

Allele Name:
sa33886
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Founder:
SL6_06_E8
KASP Assay Location:
Unknown
Mutation:
T > A
Consequence:
Essential Splice Site, Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000027550 Essential Splice Site None 226 None 6
ENSDART00000134370 Splice Site None 226 None 7
ENSDART00000145715 Essential Splice Site None 226 None 7
Genomic Location (Zv9):
Chromosome 6 (position 31053648)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 31374564
GRCz11 6 31361478
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTCAACCTGCAAATAACAGTTTCACAGTACAGTAGTCTGTTGGGTGGG[T/A]AAGTTTGAGAGCTGTTTTGCACCTCCAACCTGCTTGTTCTATGAATTTGT
Long Flanking Sequence:
ACTGTTCATTTAAATAATTAAATCATTAATTAAATCCTTTTTTTTAAATGGTCAGCAGGCTTTACACTCATATTAAATTTAAACATTATTATTTTTTAGATTTCTTATGAAAAAACTATCATTATTTATTTCTCCGCTGTAAACTTATGTTACATACACTACAAAATATTTTCTTTATAATTCCCTGTAAGATTACATACTCTGTGGGTATTGCACACTTATTGCAACCGTTATTGAAATACTACATTGACCATATTCCTCTGCGGTGCAGCCTTTGCGTATTTTTCAGATGCTAAACCAAAACCAGGCAGTGTTTTAAAATAGGGCGTTTATATTTCTCCTCCATTCATTTGCAGAGAGGAGAAGCTCACGTCCTCATAAAAGAGCAGAAGTAGGCGGCGCGTCAGCGAAGGGCTGCACTGTTTTGATGAACGCTGACAACGAGCTGTGTTTTCAACCTGCAAATAACAGTTTCACAGTACAGTAGTCTGTTGGGTGGG[T/A]AAGTTTGAGAGCTGTTTTGCACCTCCAACCTGCTTGTTCTATGAATTTGTGTTTTTCTTTATTCGGTGTTACAGATCTCCGCCCCTCATTCTGCACTGGAGATCTGTAATCTCTCGCGTTGCATCGCAAACTGTAAATAAACGAGTGTGTGTTTTGCGTGGTTTTAATTGTAACGCTGGACTCGTTTCTATTGCATACAGGGCAGTTCAGTGAGAAAATGTCCAAGTTATTCCGGGCTGTTATTATGGGTCCACCAGGTTCGGGGAAGGGGACCATCTCGGAGAGGATCGCGCACAATTTCGGCCTTAAACATTTGTCCAGTGGAGATTTTGTTCGAGAAAACATCTCCTCAAAAACTGGTGAGTGATTTGACATGAATGGCAAACTTTCGGTAGTTTTTCTGGATCTCTCTGGAAGCCTGTCGATGCCAACATGTCATATGCTCCGTGAAGCATACCGCATAAAAAAAATACTATACTACATTACAAATACTATTTTGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2314
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Founder:
mrf309
KASP Assay Location:
Project 554.26, Plate 52, Well D01
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000027550 Nonsense 169 226 5 6
ENSDART00000134370 Nonsense 169 226 6 7
ENSDART00000145715 Nonsense 169 226 6 7
Genomic Location (Zv9):
Chromosome 6 (position 31047908)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 31368824
GRCz11 6 31355738
KASP Assay ID:
554-3163.1 (used for ordering genotyping assays)
KASP Sequence:
GRGAGGCACTGATTCAGCAGGAGGATGACAGACCAGAAGCCCTGGTGGCC[A/T]GACTGAGACACTACAAAGATGTTGCCAAACCTGTCATAGACTTCTATAAG
Long Flanking Sequence:
TGTTAACAGTATTTTTTAACACAAGAAGTGATTAAACTGACGCAAACTGTTAGTAAATCCAGCCCTAATGATTGCTCTAATGTGTATTAAAAACTTTTTCCATTTACAAAATTTCCAGTTTAAATAAGTCTACCCCTAATAAAACCTACAGTATCTACATTACCTTCTTTCATAGCTTAGTTCCAGCATTTAAAAGGCTCTTGCACAAGGTAAAAAAGGCATTAAAAGTACTTCAAAATTACAACCAGGTGTTTTGGAGAAGGCTTATATCCAAACTGTGCCTCTCTAAGTAGAACTTGCTACCTTGTGGGGGAAAAACCTTGGAGAAGAATCTTATGGTTGATTTCACTGTCAGTTCTTGCCATAGAATTAGTTGTACACATCAGGGTAAAATACCTGTTTTCACTATTATTATCCTTTATGTATACAAGGGGCTGGATGACATCACAGGGGAGGCACTGATTCAGCAGGAGGATGACAGACCAGAAGCCCTGGTGGCC[A/T]GACTGAGACACTACAAAGATGTTGCCAAACCTGTCATAGACTTCTATAAGTAAGCTTATAGTCATTCTGCACTCATATTTCCTCACAATTTGAAATGTACAGCGAATCCCACACAAACTCAATGGGATGAATGTCAAAACTCATAATAATAGTAAATAAATGTTAAATGCATTCATGATGAGGATATACAGTTAATTAATAGAATTTAATTCATTTGAAACTTTTAGCTCTTCATTTTATTAAATCAATATAGATAATTAAATCTTAAGATTGATCTCTACATCATATGGCACATGTATAACACATATATGTTCACATATATGCCAGAAACATATGGCACATTTATGTAATAACTTAATGGATGCCCCATAAATGTTAAAATTAAAATCTTCTCTCAGTTGAACAGAAATTGTGAAAAAATAAACAGGGGCGCTAATAATTTTGACTTCAACTGTATATGTCCACAAATATGCCAGAAACATATTTGTCCCCTACATGTA
Associated Phenotype:
Not determined