Busch Lab

ZMP

fn1b

Ensembl ID:
ENSDARG00000006526
ZFIN ID:
ZDB-GENE-030131-6545
Description:
fibronectin 1b [Source:RefSeq peptide;Acc:NP_001013279]
Human Orthologue:
FN1
Human Description:
fibronectin 1 [Source:HGNC Symbol;Acc:3778]
Mouse Orthologue:
Fn1
Mouse Description:
fibronectin 1 Gene [Source:MGI Symbol;Acc:MGI:95566]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa553 Nonsense Available for shipment Available now
sa19408 Essential Splice Site Available for shipment Available now
sa39535 Nonsense Mutation detected in F1 DNA Not yet available
sa19407 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa553
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000017312 None None 194 None 8
ENSDART00000023692 Nonsense 36 2408 1 45
ENSDART00000103755 Nonsense 36 2500 1 46

The following transcripts of ENSDARG00000006526 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 4432026)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 4845067
GRCz11 1 5542872
KASP Assay ID:
554-0463.1 (used for ordering genotyping assays)
KASP Sequence:
TCCACTGCATGCCACAATCCGCAGGGAAAAKTAAAAGACAAGCCCAGCAG[C/T]AGCAAATCCACCTGGACACAGTTTACGAAGAGGCCAGGAGTTTAGCCATC
Long Flanking Sequence:
GTACTCATTTATGCTGAGCACTATATATATATATATATATATATATATATATATATATATATAAACAAAACTTGTTCAGCTCTGAATAAATGTGAACTCTATTACCTGCGGGTTCATGACTGCGCAGGTGATGCTTGAGTTTTGCCAGATTTCCCGACAGTGACGCAGAGACGGGAGAGGGTGAGAGAACCTCATAAAGCCCCCAAACACACACACACACACACACACACTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCCTGGATAAAACCCCCCTTTAAAAGAGCACTCGTCCCACATCAGCTGGACGGCGGAGCTGCAGTACTGTACAGTCAGGGGAAGCAGCCGAAATACAGTCAAAGCCAGAAGCTGCTCTCCATAACGCGGGTGAAAATGACCCGTGAGTCAGTAAAGAGACTCCTGCTGCTGCTGTGCATCGGCGGATCTGTCCACTGCATGCCACAATCCGCAGGGAAAAGTAAAAGACAAGCCCAGCAG[C/T]AGCAAATCCACCTGGACACAGTTTACGAAGAGGCCAGGAGTTTAGCCATCCACGAAAGTAAGTTCATCGACTTTTTTATATGCAGAAAAAATACAAACATTTCATAGCACATCTGAAATTGAATGTCTTTATGTGAGCACAAGAGGACAGTTCGCGGTTTAAGTGAGATATAGTGTCATATAATTATTGTTTTAGTATTTAATGTCGTTTTTTTACGTCCCTTCAGGTGGCTGTAATGACAACGGTCGTGTTTACAGGATGAACGATGAGTGGGAGCGGCCCTACATGGACAGCACTCTCAAGTGCACTTGTGAGGGAGCTTCAGGGGTCAAGTGTAGATCCAAACCTGCAGGTGAGCGCTTATGCGTTTATAATTCGTGCTCGTTTATTATTATTTTGAGATTGTATTCATTATGACAACGTTTAATAAATGCTTTCCTGTTATGCGTATTAAGTACCTATATAGTCATTAAAAAGTTATCTGGTCAAATTCTGTCAGC
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037
whole organism
ZFA:0001094
quality
PATO:0000001
normal
PATO:0000461

Mutation Details

Allele Name:
sa19408
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000017312 None None 194 None 8
ENSDART00000023692 Essential Splice Site 55 2408 None 45
ENSDART00000103755 Essential Splice Site 55 2500 None 46

The following transcripts of ENSDARG00000006526 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 4431967)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 4845008
GRCz11 1 5542813
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACCTGGACACAGTTTACGAAGAGGCCAGGAGTTTAGCCATCCACGAAAG[T/A]AAGTTCATCGACTTTTTTATATGCAGAAAAAATACAAACATTTCATAGCA
Long Flanking Sequence:
TATAAACAAAACTTGTTCAGCTCTGAATAAATGTGAACTCTATTACCTGCGGGTTCATGACTGCGCAGGTGATGCTTGAGTTTTGCCAGATTTCCCGACAGTGACGCAGAGACGGGAGAGGGTGAGAGAACCTCATAAAGCCCCCAAACACACACACACACACACACACACTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCCTGGATAAAACCCCCCTTTAAAAGAGCACTCGTCCCACATCAGCTGGACGGCGGAGCTGCAGTACTGTACAGTCAGGGGAAGCAGCCGAAATACAGTCAAAGCCAGAAGCTGCTCTCCATAACGCGGGTGAAAATGACCCGTGAGTCAGTAAAGAGACTCCTGCTGCTGCTGTGCATCGGCGGATCTGTCCACTGCATGCCACAATCCGCAGGGAAAAGTAAAAGACAAGCCCAGCAGCAGCAAATCCACCTGGACACAGTTTACGAAGAGGCCAGGAGTTTAGCCATCCACGAAAG[T/A]AAGTTCATCGACTTTTTTATATGCAGAAAAAATACAAACATTTCATAGCACATCTGAAATTGAATGTCTTTATGTGAGCACAAGAGGACAGTTCGCGGTTTAAGTGAGATATAGTGTCATATAATTATTGTTTTAGTATTTAATGTCGTTTTTTTACGTCCCTTCAGGTGGCTGTAATGACAACGGTCGTGTTTACAGGATGAACGATGAGTGGGAGCGGCCCTACATGGACAGCACTCTCAAGTGCACTTGTGAGGGAGCTTCAGGGGTCAAGTGTAGATCCAAACCTGCAGGTGAGCGCTTATGCGTTTATAATTCGTGCTCGTTTATTATTATTTTGAGATTGTATTCATTATGACAACGTTTAATAAATGCTTTCCTGTTATGCGTATTAAGTACCTATATAGTCATTAAAAAGTTATCTGGTCAAATTCTGTCAGCAATATAAAGCCTTTGGTTATAACATATATAATTTTTTGTACATGACAAAATGTCTTATG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39535
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000017312 None None 194 None 8
ENSDART00000023692 Nonsense 871 2408 18 45
ENSDART00000103755 Nonsense 871 2500 18 46

The following transcripts of ENSDARG00000006526 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 4413502)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 4826543
GRCz11 1 5524348
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGAGCTCATCCTCCCTGAGACTCAGACATCGGTGACACTGGGTGACCTA[C/T]GACCTGGCCTGTCATACAATATCAGCATTTACTCAGTGGAAGACAACTTG
Long Flanking Sequence:
ACGTTGATGTTTATGAAGTCAATCCAGAAGGAGATACAAAACTCATCCTGACTACAACTCAAACCACTGGTAAGATCACTGTATGTAGTGTCTTAGTTCCTGCTTACAACAGCAAAACCTTTTTGATTGTTCAAAATTATATGTACTACACTTTTTAAAGATTCACATTTTAACCAGCCGTCAGAATGTGCCTTCAAATGAATCTCCTATCTATTCACAGCACCTGATGCTCCAACCAATCATGAGGTCTCAAATGTCCAGGAGACCTCCATTGTGATCAGATGGTCCAAACCCAAAGCACCCATTACTGGTATAAGATATGCAAACCAACATTTGGGATTTAAGAATGTCTTATAAAGTTGTCTTTTGAGCATGGTGTATTGGAATGTGGAATGAACTCTTTTTCAGGCTATCGTGTGGTGTACACACCCTCAGTCGAGGGCAGCAGCACTGAGCTCATCCTCCCTGAGACTCAGACATCGGTGACACTGGGTGACCTA[C/T]GACCTGGCCTGTCATACAATATCAGCATTTACTCAGTGGAAGACAACTTGGAGAGCGAACCTTTGGTCCTGCAGGCAAGCACAGCTGGAGAGCAACAGCCCGGTAAGAGCTCCTTTTATGGAGAAGAGATTTTTCATTTTTATAGCTTTCTGCTGTTTCAGTTAGCCTGTTTGTCAAAATATTCTCCACTCACACGTTCCTAGTATTTTATCTCTGCATTAAGTTCAAAGAGCTATTATTAAGAGAATTTTACTAACTTTTCTCAAAGCTGGTAAAAATGCCCAAGTTTCTCACTCATGTGTAAAAATGTCTGTTCACAGTGAGAGCTGGCACTAGCAAATGTCTGAGCTGGGAGATTTAGAGCTTACTCAGGGCCAAAACAACCTTATAAGGATAACCAAGTTTCAAGTGTGTCTTTGGGGGCTCAAATGTCCAGTTGATGTCTTTTTAACCAAACACATGCTACTTTATGGGAACTGTGAAGTGGTTTCTTCCGTGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19407
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000017312 None None 194 None 8
ENSDART00000023692 Essential Splice Site 1983 2408 None 45
ENSDART00000103755 Essential Splice Site 2075 2500 None 46

The following transcripts of ENSDARG00000006526 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 4400491)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 4813532
GRCz11 1 5511337
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAGCTTTTTCCACGCAATAATGTTGGCCAGAACTATGCCACTATAGCCGG[T/G]AAGACACACATTGCATCACATTACAACCAGATGTGTAATAGACAGCAGTA
Long Flanking Sequence:
TAGTGTCTAAAATGTATGAAGTTTCTTCAATTTATTACAAACTTTTGTTTTTTTTTATGATGTTGGGGTATTGCCAATAATTGAAATAACTGTATTCCATACATCAGGTTTGCATCCAGGTGTCATGTATGTGGTCAACATGTACACAGTAAATGGAAACATGAGAAGTCCTCCTTTCACAATGACTGTAAACACAGGTACAAAGTAGCTTTACCTAAATAGTGCTGATTTGAGGTGAATTCTCAAATTTAATTGACTGACATTGCTCGCTATGACCTTAAACTTTTATTTTCACTCTATGCAATTACAGCACGTCCAGCTGTTCAGTCTCCAACCAACCTCCAATTCACCTCCCTAACCCCTAATTCCATCTCCTTCACTTGGCAAGCCCCTCCAACACACATCACAGGATATTATATTACTTATGAAGAATCAGGTGGCTCACCTCGTGAGCTTTTTCCACGCAATAATGTTGGCCAGAACTATGCCACTATAGCCGG[T/G]AAGACACACATTGCATCACATTACAACCAGATGTGTAATAGACAGCAGTAAATAAATAAATATCTTAATTTGTCTTGTGAATATATTTGTGATTTTTAAATTCAGGTCTAAAACCAGGCACTGAATACATTATTAAGATCATTGCCCTTCTGAATAACCAGAGAAGCGCACCACTAGTTGGCACAGCCACAACTCGTAAGTATTTACTAATATTCAATTCAATTTCAATTCAGCTTTATTTGTATAGCGCTTTTACAATGTAGATTGTGTCAAAGCAGCTTCACATAAATGGTCATAGTAACTGGAACAGTGTAGTTCAGTTTTTAGTGTTTAAGTTCAGTTTAGCTCAGTTCAGTGTGATTTAATCATTACTGAGAGTTCAAACCCTGAAGAGCAAATTCATCGATGCGTAGCTCTACCATTCCTGAACCATGCGAGCCAGTGGCGACAGCGGAGAGGGAAAAAAAACTTCACCTGATGGGAGTGAAGAAAAAAAACCT
Associated Phenotype:
Not determined