Busch Lab

ZMP

zgc:92316

Ensembl ID:
ENSDARG00000006508
ZFIN ID:
ZDB-GENE-040912-141
Description:
phosphatidylinositol-4-phosphate 5-kinase type-1 beta [Source:RefSeq peptide;Acc:NP_001004579]
Human Orthologue:
PIP5K1B
Human Description:
phosphatidylinositol-4-phosphate 5-kinase, type I, beta [Source:HGNC Symbol;Acc:8995]
Mouse Orthologue:
Pip5k1b
Mouse Description:
phosphatidylinositol-4-phosphate 5-kinase, type 1 beta Gene [Source:MGI Symbol;Acc:MGI:107930]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa7122 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa41132 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa13090 Nonsense Available for shipment Available now
sa21206 Nonsense Available for shipment Available now
sa34316 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa7122
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008215 Essential Splice Site None 527 2 15
Genomic Location (Zv9):
Chromosome 8 (position 11417647)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 11251477
GRCz11 8 11289182
KASP Assay ID:
554-4906.1 (used for ordering genotyping assays)
KASP Sequence:
GCAGCAGCGCTGAACCAAACACCAACACCTGTGCTCTTGGTTAAATCAAG[G/A]TAAACCATAATTGCATMATWTATTATTAACAGAACCRCACATTTGCTGCA
Long Flanking Sequence:
AATAATTACTAATATTATTAATTCATATACAATTTCTGTTTTGCCTTTTAATATATTTTAAAAACTTTTAGTTTATTTCTGCACATCAATATTAACCAATAAATGTAATAAAAGCCACATAAAATATCAGATCAATTTCAAAATCTTATTTATTGCTCCTCATCAGTATTAGCCAACTAATAAAATGCATATAAAAAGTATTAATCTATATAAAAATAAAACATTTTATAACATAAAATGTGAGACCTTATAAATAAAATCCAATCCTTTTCTTCAGATTGTGAGTTGAATTATGACCTCGACATGTTCTTGACCTCATGCTCACGTCGTTGTCGGTCATTAAAACCCAACCGCTGCCTCATTAACTCTGCTTTAACCTTCTGGTTTTACAGGAGGAACATCATCATTGTGAGCTCCACTTGTGCTTTCTGGTCCACATGACTGCGCAATGCAGCAGCGCTGAACCAAACACCAACACCTGTGCTCTTGGTTAAATCAAG[G/A]TAAACCATAATTGCATCATTTATTATTAACAGAACCACACATTTGCTGCATTTACAAGGCACTCGAGTTCTCCATCAGGACGTCCTGCTGTGCGTGTCGGGCTCTTTTGCAAATCAGATGGTTTCTGGTTTGTGGATGGAGCCTGAGGAGATTATTTACATGCCCTGCTGATGGTTTTGTGTGACGTTTAACTCTTTGTTGTCTCGTGCAGATGTCATCAGCCAATGCCAATGGAGTCGGGAGCTCTGGAAATAACCGTAGAGAAAAAACATACAAAAAGGTGCATCAACTGTTTTTCAGTCTTGTGTTTGTTGCTGAAATATGGAGAATGCTATGTTTTTTTGTGTGTTTGTGCATACATACAGTTGAAGGCAAAATGATTAGCCGTCCTGTAAAATTTATTCATTTCCCTTCAGCTTAGTCCCTTATTTATCAGTGATCGCCACAGCGGAATGAACCGCCACCTATTTCAGAATGTTTTAAGCAGTGGATGCCCTTCC
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa27134
Status:
Less stringent filtering
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008215 Nonsense 50 527 4 15
Genomic Location (Zv9):
Chromosome 8 (position 11421649)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 11247475
GRCz11 8 11285180
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCCAGCTCGGCATCGGCTACACCGTAGGGAATCTGACCTCAAAACCTGAC[C/T]GAGATGTGCTCATGCAGGACTTCTACGTGGTGGAGAGTGTGTTTTTACCC
Long Flanking Sequence:
TCATCATTTTATTTTACAGGAAAGCCTAAATGAATTCATACATGTGATTTGAATGACATGAGAGGCGATCTCTCTGCAATCTTTGAAAATTTAAGATTAATAACAAAAGAAACAAACAAACAAAAGAAGTATTGATCCGCGGGTCATGTGTGTTCTAAACTGCACAAATCATGGATCTAACGTGATCCATTACACCCAAGTATCAATGAAGAAAACCCTACCAATGAACTTTCTAGAATTTTTTGGCTGATCTAATACTTGACGTGACCCACAGCTGTCATTTATTCAACCAACTGAGATTTAGGAAGGCAGGTTTAGTCTTGCGTGTCTGAGAAAATGACCTCAAGAAACCCACATAAGAGCTGGGTTCGAAATGACTAAGCGCTATGCTAATTTGTTTTGCTTTTTTATTATTGTTGCAGACTACTTCATCTGCTCTAAAAGGAGCCATCCAGCTCGGCATCGGCTACACCGTAGGGAATCTGACCTCAAAACCTGAC[C/T]GAGATGTGCTCATGCAGGACTTCTACGTGGTGGAGAGTGTGTTTTTACCCAGGTATGGATGGACACAGGCAGTACACCAGTGTATGTTAAACGTGCTGCTGTCAAACTGGTGTGAACGTTTCTTAAATTCCCTCCTATAGCATTTAGTGTGGTCAGACAGCATGCTGTCATTTGACTCTCAAAACAAGTTTTTAAAGGGACAGTTCACGCAGAAATGACAGTATGCTGTTAATTCACTCAAGCAATGTTTTTTACATTCATTTTCTTTTCAGCTTAGTCCCTTTATTAATCAGGGGTCACCACAGCGGAATGAACCGCCAACTTATCCAGCATATGTTTTACGCAGCAGATGCCCTTCCTGCCGCAACCCAGCACTAGGAAACACCCATACACTCTTGCATTTACACACATACACTATGGCTAATTTAGTTAATCAAATTCATCTATAGCACATGTCTTTGAACTGTGGGGTAAACTGGAGCACCCGGAGGAAACCGACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41132
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008215 Essential Splice Site 106 527 5 15
Genomic Location (Zv9):
Chromosome 8 (position 11428258)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 11240866
GRCz11 8 11278571
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTCCGCTACTTCCGGGAGCTGTTCGGGATCAAGCCGGATGATTATTTGG[T/G]AAACTTTTTTAAATTTGTTGTTGTTATTAGTATATTTATTCTTTGTTTTT
Long Flanking Sequence:
GTCAATATTAGTAGCCCCCTTAAGCAATATTTTTTATTATTTGTCTACTGAACAAACCATCATTATACAATGACTTTCCTATTTACCCTAACCTAGTTAAGCCTTTAAATGTCACTTTAAATGTCACTTTAAGCTAATACTAGTATCTTGAAAAATATATTTAATACTAGTATCTAGAAAAATATCTAGTAAGATATTATTTAATGTCATCTTCAGCAACGATAAAATAAATCAGTTATTAGAAATGAGTTGTTATAACTATTATGTTTAGAAATGTGTTGGAATAAAAATCTTCTTTCTGTTAAAAATAAAGAGAGAGGCTAATAATTCTGACTTTAACTGTATGCTTCATTTTTTAAGCAAGTACTTTTACTTTTTCAGTGAAGGAAGCAACCTGACACCAGCACACCATTATCCAGACTTCCGGTTCAAGACTTATGCGCCACTGGCTTTCCGCTACTTCCGGGAGCTGTTCGGGATCAAGCCGGATGATTATTTGG[T/G]AAACTTTTTTAAATTTGTTGTTGTTATTAGTATATTTATTCTTTGTTTTTGGTGTGAAATGCGCTTTATAAATACACTTAATTTTTAAAATGTTACAAAGGTTTTTTAAAGTCTGTGTGAAATCCATATTTACTATGTGTTTTTCACATAACACACATTGTTAAGCCGCCTTTCCACTGCACACGACAAATGACAAGTGACAGACCGTCTAGTTTGCTACAAAATAATGATGTGCAAAAAGAAAGCCCCGCCCACTACTCAGTTTTTGGTTTTAGTTGGAAGTACATCAACACACCGAAATAAGTCTCAGCAGCTTTTGCTTTACATTTACTTTTAAAAAAAGCAATACAGTTTCTATACTTTTATTCAAGTCAAGTTTTTTTATGTCTTCTATATTGTCCCAACTTTTCCTGATTTGGGGTTGTATTACAATTTAAAACAATACTTTTACTCATCAAGCGTGCATTATATTGATGATAAGTGACAGTAAATACACTGTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13090
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008215 Nonsense 225 527 7 15
Genomic Location (Zv9):
Chromosome 8 (position 11439383)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 11229741
GRCz11 8 11267446
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TACAAGAGACGKGCGTCAYGAAAAGAGCGGGAAAAGCCCTGTCCCACATA[T/G]AAGGACCTAGACTTWGTGGACATGCATGATGGYTTGYACTTTGACCCAGA
Long Flanking Sequence:
TTAGCTTTTTGTGTTTGTTTGCTCTAAAAACTATAAATCAAAGTTGACAGGGCTCAGATGTTTTGTTTGCTGGAGTAAATGAGGCACAATCTGTAAAGGAACTGCCCCCTTTAGAAAGGTGGGGCGGGGAGTAGCAGCTCATTTGCATTTATAGAGATATATGCGAAACTGCCTAAAATAGGGTATATAAAGTGTGATATATTAAGTGATATGTGAGGTATTTTGACCTGGAACTTTAAACACATTAAAAAAAATAATGCATAATAGGCTTTAAATAAATCTATTTCTCCTTCTCAGAACCTCAACCAGAACCCCAGGACGCTCCTACCCAAGTTTTACGGCCTGTACTGTGTTCAGTCTGGAGGAATCAACATCCGTCTCGTGGTTATGAACAACGTCCTGCCGCGATCAGTGAAGATGCACTACAAATATGACCTCAAGGGCTCCACATACAAGAGACGGGCGTCACGAAAAGAGCGGGAAAAGCCCTGTCCCACATA[T/G]AAGGACCTAGACTTTGTGGACATGCATGATGGCTTGTACTTTGACCCAGAGACATATAATGCCCTGATGAAGACACTACAACGGGACTGTCGGGTGAGTTATACAGTATTTTGTCCTTTTACAAAGAAGCTGTGAGTGGTGAGCAAAGTTGCGCACAATTCTAGTTTGTTTTTAATGGTACTCTATGTAAAGCAACTTGAAAACTAAGTGGCTTAGGGAATCACGAGGTGGACACTTGGGGTTTAGAGATTTATTTGCTTAATTTAATCATACAATAGGGTATTATGACCGTGACAGAGGGCTCTGTCACGATCACGACAGTAGGTGATTTCATTTACACACAGTGTAATATCCATCAGTGATTCTGCCGTTCCCAACCCTTTGGTGCACATAAAGGTTGGGACAATGTTACCATTGCATATATAACGCACACACATACATTCACTCATCACCACAATTCCCAAAAAACACACACACAGACACCAAATACATTTATTGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21206
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008215 Nonsense 266 527 8 15
Genomic Location (Zv9):
Chromosome 8 (position 11456011)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 11213113
GRCz11 8 11250818
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGTGTTAAAATGTGCTGTAGGTGCTGGAGAGTTTTAAGATCATGGACTA[C/A]AGTCTCCTGCTGGGGGTTCATGTTCTGGATCAGAGTCACAGAGATGGAGA
Long Flanking Sequence:
TAATATAATATAATATAATATGAGTATAATTTAATTAAAAATAATATAATATAATTTAAAATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATTCCCAGAGATGGGTTGTGGCTGGAAGGGCATCCGCTGCATAAAAACTGGCTGGATAAGTTGGTGGTTCATTCCGCTGTGCCGACCCCAGATTAATAAATGGACTAAGCCCACAAGAAAATGAATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATTAATATAATATAATATAATATAATATAATATAATATAATATAATATTTAAATTTCTAATATTGTTTTGCATGTTACCATGGCACCATTTTTTATCTCGGTGTGTTAAAATGTGCTGTAGGTGCTGGAGAGTTTTAAGATCATGGACTA[C/A]AGTCTCCTGCTGGGGGTTCATGTTCTGGATCAGAGTCACAGAGATGGAGACGGCAGTGCTGTGGACGGGAAGAGAACTGTGGGACAGAAGGTGCTTTACTCCACCGCCATGGAGTCCATTCAGGGAGACGGAAAAGCAGCAGAGGCTTTGACCACAGACGACACGTAAGTTCAGGCTCTTTATGTCTGCATATATATATATATATATATATATATATATATATATATATATATATATCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTGTCATTTAAATTGAAATGTTGGTTTAAAGAATTGTAAACTTTGTTGACTTTTGTGAAATAATACTTAGAAAATAAATCATTACATACACTATAAACCAGGGGTGCCCAAACTTTTTCTTATAAAGGGCCAAAAACCAAACTTGATTGAGGCTAGTGGACCGAAGATAAATATAGTTGACATGAGTAATTTCCTTATTTGTTTAATAATGTTTATAAATGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34316
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008215 Essential Splice Site 394 527 11 15
Genomic Location (Zv9):
Chromosome 8 (position 11457849)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 11211275
GRCz11 8 11248980
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AACAGATTTCTCAAGTTCATGAGCAGCCGAGTGTTCAGAAAGAATCAGCG[T/G]AAGTCTACAATATGAAGATGCATTTTTGATGCAGATGCAACATTACATGC
Long Flanking Sequence:
GTAGTGAAATCTTAATGTACTTGTCCTGATCTTTTTTTTTTTTTTACACAGAATGGGAGGCATTCCTGCAAAAACACACAGGGATGAGAAAGTACTTATTTTCCTAGGCATTATCGACATCTTGCAGTCTTATAGGTAAGTCTGTTCTTGGTTTACAGCAAACCCAAGAGATCCAAATGTCAAATTACACACCATCAAATGACTGATTCCAGCTTCTTTGAACAAACTCCATTATCCCTCATCTCGCTCCTGTTTTTGCACCCAGATTCATCAAGAAGCTGGAGCACTCCTGGAAGGCGCTGGTCTATGATGGCGTAAGTCTATATGTCTTCTCTTATGAATAGACTATTCATAGCGCATGAGGGAATTAAAGACTCTTCCTGGTTTGATTGTGTTGTATTCTGTTTCTCCTAGGATACTGTGTCTGTGCACAGGCCGAGTTTCTATGCAAACAGATTTCTCAAGTTCATGAGCAGCCGAGTGTTCAGAAAGAATCAGCG[T/G]AAGTCTACAATATGAAGATGCATTTTTGATGCAGATGCAACATTACATGCGGTGCAAGTTGCAAAGGCAAAATGTGTGTTTTTGTTCTGAAAACTGGGTAACAATTTGCATTCGGTAATCCTTGTGTATTGTTCAAATTGACTACCCTTTCATTAGGTTCGTGGCTGTTTTTGCATTGGCTTCCATTATAATGACATTTTTTGATTGCAAAGCTTTGATACCAAATAATCATGCACTCCTTATTGTTGATGGTTTTACCAGTAAAGTTTGTAGGGCTCTATTTTAATGATCTAAGCGCAAAGTCTAAAGCGCATGACACAAAAGCATTAAGAGCATGTCCGTATCCTCTTTTGCTATTTTAAGCATGGACAAATATGGTCTGCACCCTGGCATATGGTCTAACAGGGTTGTGCTTATTCTATGAGTTATGGGTGTGTTTTGAGCATAACTTGCATTAAACCAGTCATAGTTTCATCTCCCATTCCCTTTAACGCCCGATT
Associated Phenotype:
Not determined