ZMP

akr1b1

Ensembl ID:

ENSDARG00000006215

ZFIN ID:

ZDB-GENE-040625-7

Description:

aldose reductase [Source:RefSeq peptide;Acc:NP_001002048]

Human Orthologues:

AKR1B1, AKR1B10, AKR1B15, AKR1E2

Human Descriptions:

aldo-keto reductase family 1, member B1 (aldose reductase) [Source:HGNC Symbol;Acc:381]
aldo-keto reductase family 1, member B10 (aldose reductase) [Source:HGNC Symbol;Acc:382]
aldo-keto reductase family 1, member B15 [Source:HGNC Symbol;Acc:37281]
aldo-keto reductase family 1, member E2 [Source:HGNC Symbol;Acc:23437]

Mouse Orthologues:

Akr1b10, Akr1b3, Akr1b7, Akr1b8, Akr1e1, Gm6736

Mouse Descriptions:

aldo-keto reductase family 1, member B10 (aldose reductase) Gene [Source:MGI Symbol;Acc:MGI:1915111]
aldo-keto reductase family 1, member B3 (aldose reductase) Gene [Source:MGI Symbol;Acc:MGI:1353494]
aldo-keto reductase family 1, member B7 Gene [Source:MGI Symbol;Acc:MGI:101918]
aldo-keto reductase family 1, member B8 Gene [Source:MGI Symbol;Acc:MGI:107673]
aldo-keto reductase family 1, member E1 Gene [Source:MGI Symbol;Acc:MGI:1914758]
predicted gene 6736 Pseudogene [Source:MGI Symbol;Acc:MGI:3643048]

Alleles

There is 1 allele of this gene:

Allele Name	Consequence	Status	Availability
sa16601	Essential Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa16601

Status:

Available for shipment
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Availability:

Order Allele From ZIRC
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Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000018261	Essential Splice Site	142	315	4	10
ENSDART00000122523	Essential Splice Site	172	345	5	11

Genomic Location (Zv9):

Chromosome 4 (position 13968877)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	4	14904730
GRCz11	4	14903485

KASP Assay ID:

2259-4726.1 (used for ordering genotyping assays)

KASP Sequence:

AGGATGGCCATGTGATTCCAGACAACAGCAACTTTCTCGAAACATGGGAG[G/A]TAATAAACAGTAGAATAATTGAGATTACAGTAATGATCATGTCAGAATTA

Long Flanking Sequence:

TTATGTAATCCTAACGAACTTAAAATAGTAAATGTTTAGTATGATTTACCATCAGACATTTTTTTTTTTAATTGGTTATCTTCCTTGTTTAGAGTGTATTTAAACTTCTGGTTTCAACTGTATATGCATAAGCTCCTTGCTGATAAATCTCTTAAACAGTGTTAAAGAAAGGTAATACATTTAAAATGATTATTAATTTGTAAGTATGGGTAGCACTGTGATCTTAGAGTCATTTATAAGTCATTAAATAGTTCTTGATTTAAGATGACGACAAGGTTTTTGGTCGTTTCACTGAATTTCAGTGGGCGTCTTCTCTAAATGAAATTGAATTATTATTCAATTTAAGGCTGTTATTGCTTTAATTAAAAATAAAAAAACACCATTTATATTATGATTACACTTATTTTTGTTCATCTGTGTAGCCTGGAAAGGATCTTTTCCCACTGGATAAGGATGGCCATGTGATTCCAGACAACAGCAACTTTCTCGAAACATGGGAG[G/A]TAATAAACAGTAGAATAATTGAGATTACAGTAATGATCATGTCAGAATTACATTTGACAATTGTTGCTTCATTTTCACAAAGGCAATGGAGGAGTTGGTGGACGCTGGGTTGGTTAAAGCCATCGGCATCTCAAACTTTAACCGGGATCAGATTGAGGCAATCCTGAATAAACCAGGGCTCAAATACAAACCTGCCAACAATCAGGTACATTCATTCATTTTATTCTCAAACACATTTTAAGAAAATGAAACAGATGACGACTTAAAGCCCAAGGTTCACAGAGAAGGCTTTAGACTAGTTATTGAATAAACTGACAACACATATGTTTTGTCTTAAGATGCACACAATTAACGAGGTTTTTCTGAGGCGATTTTATAAAAGCTGCTTAAGTACTTGCCCTAATTTAACTATTTTATTTCTAGCTTAAGCCATGTCTTGTTTGTGAAACAGGGCCATCAGTTCTCTTCTGAAAATACTTGAAATAATTGTATTTTTATTT

Associated Phenotype:

Not determined