Busch Lab

ZMP

nek2

Ensembl ID:
ENSDARG00000005619
ZFIN ID:
ZDB-GENE-040426-752
Description:
serine/threonine-protein kinase Nek2 [Source:RefSeq peptide;Acc:NP_957344]
Human Orthologue:
NEK2
Human Description:
NIMA (never in mitosis gene a)-related kinase 2 [Source:HGNC Symbol;Acc:7745]
Mouse Orthologue:
Nek2
Mouse Description:
NIMA (never in mitosis gene a)-related expressed kinase 2 Gene [Source:MGI Symbol;Acc:MGI:109359]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa6622 Nonsense Mutation detected in F1 DNA Not yet available
sa14846 Nonsense Mutation detected in F1 DNA Not yet available
sa36991 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa6622
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003248 Nonsense 234 440 6 10
Genomic Location (Zv9):
Chromosome 20 (position 13801842)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 13991088
GRCz11 20 13887068
KASP Assay ID:
554-5231.1 (used for ordering genotyping assays)
KASP Sequence:
CAGCATACAAYCAGACAGAGCTGGCTCGAAAAATCAGWGAAGGCAGATTT[C/T]GAAGAATCCCATACCGATACTCGGATGAGCTAAACRCACTGCTTTCAAAA
Long Flanking Sequence:
TTTCTCTTACGTTCACAGGAACAAATGAATCGCATGTCCTATAATGAGAAATCGGATATATGGTCTTTAGGGTGTTTACTCTATGAACTATGTGCTTTATCGTAAGTATAAATGTATTCTTGTTCTCCTCAGTTTTTTTAATACTGTGTACATTGACTGAATTTAAAGGGATAGTTTAAGCCAAAAAATAAAAATTCTAGCAATATTTACTCACAATTCACTTGTTCCAAAACTGTTTGAGCTGTTTTTTTCTGTAGTACACAAAAGATATTTTGAAGAATGTTGGGGAAAAACTTCAACAGTATGTCAAAGGGTGCTTTCCCCCCCACGTTCTTAAGAATATCTTTTGTCTTCAACAGGTGAAAGAAATTTAAAAGTATATAAAAGTTTAGAACTGATTGAGTGTGAGTTAATGAGAAATTTTATTTATTTTTTTTAGGCCCCCATTTACAGCATACAACCAGACAGAGCTGGCTCGAAAAATCAGAGAAGGCAGATTT[C/T]GAAGAATCCCATACCGATACTCGGATGAGCTAAACACACTGCTTTCAAAAATGCTCAACTTAAAGGTAAATATTGGTGAGGGTAAAGTATGCAACAGTCTGAAAGTAACAACACCACTCATTGTCTTCATTGTGAATTCAATTGTATTGTATAACAGCTGAATTTGTGGAACAACTGTATCTGTAGTAAACAATATCCATGACCCTGTTTTTCACAGTGGAATATGGGATCTCCACCTTCATCTGCAAGCATATTAATTTTATTTTATCTGTGCATTTATGTTTCTACTCTAACATTGAACTGTCTTAAAAGTTAAGATTAAAAACACTATATCTACCTTCTACCAAAAAGTGCATTTCAACACCATTTCAAACATGTGATTCAATTATTTACAATATAAAAGTATGCTGTTTGTTCACAAAACATACAGTACATTCACCGGCCACTTTATTAGATACACCTTACTAGTACCGGGTTGGGCCCCTTTTTGCCTTCAGGAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14846
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003248 Nonsense 254 440 6 10
Genomic Location (Zv9):
Chromosome 20 (position 13801903)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 13991149
GRCz11 20 13887129
KASP Assay ID:
1641-0500.1 (used for ordering genotyping assays)
KASP Sequence:
ATACCGATACTCGGATGAGCTAAACRCACTGCTTTCAAAAATGCTCAACT[T/G]AAAGGTAAATATTGGTGAGGGTNAAAGTATGCAACAGTCTGRAAGTAACAA
Long Flanking Sequence:
GGTCTTTAGGGTGTTTACTCTATGAACTATGTGCTTTATCGTAAGTATAAATGTATTCTTGTTCTCCTCAGTTTTTTTAATACTGTGTACATTGACTGAATTTAAAGGGATAGTTTAAGCCAAAAAATAAAAATTCTAGCAATATTTACTCACAATTCACTTGTTCCAAAACTGTTTGAGCTGTTTTTTTCTGTAGTACACAAAAGATATTTTGAAGAATGTTGGGGAAAAACTTCAACAGTATGTCAAAGGGTGCTTTCCCCCCCACGTTCTTAAGAATATCTTTTGTCTTCAACAGGTGAAAGAAATTTAAAAGTATATAAAAGTTTAGAACTGATTGAGTGTGAGTTAATGAGAAATTTTATTTATTTTTTTTAGGCCCCCATTTACAGCATACAACCAGACAGAGCTGGCTCGAAAAATCAGAGAAGGCAGATTTCGAAGAATCCCATACCGATACTCGGATGAGCTAAACACACTGCTTTCAAAAATGCTCAACT[T/G]AAAGGTAAATATTGGTGAGGGTAAAGTATGCAACAGTCTGAAAGTAACAACACCACTCATTGTCTTCATTGTGAATTCAATTGTATTGTATAACAGCTGAATTTGTGGAACAACTGTATCTGTAGTAAACAATATCCATGACCCTGTTTTTCACAGTGGAATATGGGATCTCCACCTTCATCTGCAAGCATATTAATTTTATTTTATCTGTGCATTTATGTTTCTACTCTAACATTGAACTGTCTTAAAAGTTAAGATTAAAAACACTATATCTACCTTCTACCAAAAAGTGCATTTCAACACCATTTCAAACATGTGATTCAATTATTTACAATATAAAAGTATGCTGTTTGTTCACAAAACATACAGTACATTCACCGGCCACTTTATTAGATACACCTTACTAGTACCGGGTTGGGCCCCTTTTTGCCTTCAGGACTGCCTTAATCCTTCGTGGCAAAGATTCAACAAGGTTCTCGAAATATTCCTCAGAAATTTTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36991
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003248 Nonsense 324 440 7 10
Genomic Location (Zv9):
Chromosome 20 (position 13804658)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 13993904
GRCz11 20 13889884
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGCGGCTTAAAGAGCAGATTCTCCGAGAGCGAGAGCAGGCCCTCAAAGAG[C/T]GAGAGCAGCGGCTAGAGCGTAAGCACACTGTTGTTGGCCTTCTGAAAGCT
Long Flanking Sequence:
TGCACATTTGCATTGTTATAGCAAACACAACTATAAACTTATATAAAAATAATATTACATTTTGATTCCATGCCAACTTTATAGCACATTTTAATTTAAGATTATCAAACAGATTGCTCTGAGGATGTCTGCCTGCATGTTTTAGCATATAATTACCATTTTCATACATTGGCTGAATGTTTGAAACATGTTTAACACATCGTTAGCATGTATTTTTACTTCAGATGTTGACTACTATATATTGCAGAATGTGTTTGGGCACATCCTGACTGGTGGTCTTTTTTTTTTTTTGTCAGGACTATCTGAGGCCCTCTGTGGAGTCCATCCTGCAGAATGGTTTGATCTCCGGTTACGTGGCCCTCGAGCAGAAGAGGCTCCAGGAGAAACAGCGGCGCAGATCAGATGAGGCAGAGCAGCCCAAACATCCAGAGTCACCACTTCTGGCAGAGCTGCGGCTTAAAGAGCAGATTCTCCGAGAGCGAGAGCAGGCCCTCAAAGAG[C/T]GAGAGCAGCGGCTAGAGCGTAAGCACACTGTTGTTGGCCTTCTGAAAGCTAAAGGGACAGTTCAAACCATTTTATTTGTGTTATGATTTACTCATCCTCCACTTGTTCCAATCCAACATTTGTTACTTTCCTTTGTTAGATCTTTTCAGGAATGTTTCAAAAAATGCCCATAGACTGTTTTCACACAGTCTCCATTTTAAAAGCAAAATCGAGGCTGCGGTGGGAAGAAACCCAAAAGTATTGCCTGGAGCTGCACAGAGATGTTGTGTAGCTGGCTGTAAATCTTATGAGCGAAGAGAAAGTGACACGAATTTATTATTTCACCCCCTTTCGAGTGACCTGAAGGTCTGTTCTGAATGGATACTAAAAATAAAGTTGATGAACTAATTCTTTCACTGTATCAGACCTATCACAATACTGAATTTTGACAGTGAAAAAATTTTAAGGATTTAAATTTCCAGCTAATAGAAGTGCTAGAATGTTCTTAAACGCAGCTGATT
Associated Phenotype:
Not determined