Busch Lab

ZMP

NP_001128602.1

Ensembl ID:
ENSDARG00000005374
Description:
gamma-tubulin complex component 4 [Source:RefSeq peptide;Acc:NP_001128602]
Human Orthologue:
TUBGCP4
Human Description:
tubulin, gamma complex associated protein 4 [Source:HGNC Symbol;Acc:16691]
Mouse Orthologue:
Tubgcp4
Mouse Description:
tubulin, gamma complex associated protein 4 Gene [Source:MGI Symbol;Acc:MGI:1196293]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa8846 Nonsense Mutation detected in F1 DNA Not yet available
sa21080 Nonsense Available for shipment Available now
sa41027 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa2377 Essential Splice Site F2 line generated Not yet available

Mutation Details

Allele Name:
sa8846
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000009649 Nonsense 199 668 7 18
Genomic Location (Zv9):
Chromosome 7 (position 54403124)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 52673115
GRCz11 7 52944240
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGATGTATAAGCAGCTGGCGGCGTGGATGCTGCACGGGCTGCTGCYAGAC[C/T]AGAGCGAGGAGTTTTTCGTCAAGCAGGGCCCCAGTGCTGGYGGAGCCACT
Long Flanking Sequence:
TCTAAGACATCAGGAGGATTAAATGCACCACGTTTTGACCCCACAGTATATTTCTAACTTGGAGTTTTCCCTCTGTTGTTTTTATTCAGTTTCAGCTTCTCTTCCCATCTGTTATGGTTGTTGTTGAGACCATCAAGTCTCAGAAGGTTTGTATCTTAATGGGTGCCACTGGTTTGCAATGCATGATTACAAGAGTGCGTGGTTAAAAATAATAACCTTCTGAAAGTTTAGTTTTTCTATTCAATAGATTCATGGCTGTCAGATCCTGGAGACTGTATACAAGCACAGCTGTGGAGGACTGCCTCCTGTCAGGATGGCCTTGGAGAAGTGAGCACTCAGAAACACGCGCATCTAAACAGATGTATTTCTTAAACGAAAGACTCAGACTGCTATTTTTACTGTTCTAATGGTAGTGTCTGTGTCGCAGGATTCTTGCCGTGTGCCATGGCGTGATGTATAAGCAGCTGGCGGCGTGGATGCTGCACGGGCTGCTGCTAGAC[C/T]AGAGCGAGGAGTTTTTCGTCAAGCAGGGCCCCAGTGCTGGCGGAGCCACTGCTGCACAGGAGGAGGATGAGGAAGACCTGGGCATCGGAGGCCTGAGTGGGAAACAGCTCAGAGAACTGCAGGATTTGGTGAGTGAATGATATGAAGCTGAACGTCACTTCCTGAGATTCTGTGTTTGTTATTTTGATAGAACTAAGACGGTCATTAAATAATCATTTTCATTTATGTTTTTATTTACATTTTCGTTGTTGATTATATTTTACTATCTTATTTTATGCCTCAATTATTGTACATAATAATAAACAAATATTGGAAAATAAATGAATAATGAAAATAGGCCTAAATAATTATTTATTTAAAGACATTGCAGCTAAACACTGAGAAACGGTCCGGCATGGTCTAAAGAGCTTAAGTTGAATGCTGCTTCATCAAAAGTATAAAAATTAATTTACCTTCCTTGAAGCAGTTCACTAAAAGTATAATAAAAATAAATTAAATAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21080
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000009649 Nonsense 355 668 10 18
Genomic Location (Zv9):
Chromosome 7 (position 54400953)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 52670944
GRCz11 7 52942069
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCACTTATGGACTTTAATGGTAGAAGAATCTGATCTTTTGGGGCAGCTC[A/T]AGGTAAATAAAAAGTAGTTTTTTGACGATACACTTACTGGTGCAAGTTTG
Long Flanking Sequence:
TGCGTGTGGAGATGCTTCCCTCATACATCCCTGTTCGAGTAGCTGAAAAGATTCTTTTTGTTGGGGAGTCTGTGCAAATGTTTGAAAACCACAACCAGAGCCCATCGCGAGCTGGTGAGTGCTTTAGCATTTTGCCGCTGTTGTTCAGGTGTGTTTGCAATGGGTTTTGTATGCTAACACTGCCCTCGTGTGGTGGCTCAGGGTCTATACTGAAGCATCAGGAGGACATGTTTGCAGCCGAGCTCCACAGACTCAAACAGCAGCCTCTCTTTAGCCTGGTGGACTTTGAAAATCTGGTGGATGGCATACGGAGCACAGTTGCTGAGGTTAGTCCAGTCAGTTTATTGGTACAAGCATGAACCCCACAAAGCATGTATATGAAATTTCCATATCATGTATATAACAGCACTACCAAAAGCACCAGGTGAAGTCTGTGTCTTTTTTTCTTGCAGCACTTATGGACTTTAATGGTAGAAGAATCTGATCTTTTGGGGCAGCTC[A/T]AGGTAAATAAAAAGTAGTTTTTTGACGATACACTTACTGGTGCAAGTTTGCCAACACTAGGCATGGGCCGGGATAAGTTTCTCATGGTAGGATAACCTTGGTATTGTGAGTACTGTTTTAAAATAGGTTATTTTACATTTTAAACATTATTTTAAATGTCTGGGTGAAAAACTAAAACATTTTCTCCTTTAAACACAATATTTTTTTTTATTTTTAAAAATGTTTGCAGTATTTTGTAACTAAACATGACAGGCTAAATAATTCAAGTGAATCATTGACTTATGCTGTCTTCATTCAAAAACACAGATTTCTTTACTATTTAAAACAGCATTTTTGGAGATCTTTCCAACTGGAGATACTGGTGTCCTAAAAAAAAAGGAAATAAAAAATCTTACACACACTTTAGGAATGGTATAGTAGAAAATTTTGACACTTTTAAAACCAATTTTTTTTACCAACCGTGGTATACTTTGAAAACGGTTATCGTCCCATGCCTAGCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41027
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000009649 Essential Splice Site 427 668 12 18
Genomic Location (Zv9):
Chromosome 7 (position 54396345)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 52666336
GRCz11 7 52937461
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGCCACTCCTCCACCTCACCATAGACTACCATGGAAAAGAAAGCAAAGG[T/C]ATTTCTGACTGACAAGCATTTTCATCTACATATGAAATACACATCATTTA
Long Flanking Sequence:
ACCTCCACACCCCCGAGGCAGTGAGCGGTTTGGTGCCTTGCCAAAGGGGCTCACCTCATCCATAGTATTGAGGGTGGAAGAAAGTGCAGGAAATTCATTCGATGCACCTACAATCCCTGCTGGTTTCATGACTCCGATGTGCAATTTAGATCTCTAATGTCTATTCTAACAGTGAAAACCCATAATGAATGGTCTGTTGTTATTGTTTTAGATCATAAAGGACTTTTTCTTGTTGGGGCGAGGTGAACTCTACCAGGTCTTCATTGACCTTGCTCAGCATATGCTGAAAACCCCACCTTCTGCTGTTACTGAACATGGTATTAATACAACTTACTTTATAAACCATAAACTTTTCTCCATTTCTCTAAATATATCACAATTTTTTTTCCAGATGTCAATGTGGCATTTCAGCAAGCGGCTCACAAAGTGCTGCTCGACGATGACAATCTTTTGCCACTCCTCCACCTCACCATAGACTACCATGGAAAAGAAAGCAAAGG[T/C]ATTTCTGACTGACAAGCATTTTCATCTACATATGAAATACACATCATTTAATCCTTGTGGTTGTAGAGGGTTCTGGGAATCGAGAGGGCACCACTCCACCTCAGGAGAGCTCTCCTCGTGAAGCTCCGCCCACTGGCTGGGCTGCACTGGGATTGGCTTACAAGGTTCAGTGGCCTCTGCATATTCTTTTCACTCCTGCTGTGTTGGAGAAGTAGGTCATCATTTTATGTTATTATTAGTTTCATATTATTATTTAGCATGAATATAATAACTATTTATCATTAACTACATGACTACAGGTATAATGTAGTGTTCCGGTACCTGCTGAGTGTGCGTCGAGTCCAGTCCGAGTTGCAGCACTGCTGGGCTTTGCAGATGCAGCGCAAGCATCTCAAATCAAACCAGACGGATGCAGTAAAATGGAGACTCCGCAACCATATGGCCTTCCTAGTGGACAACCTTCAGTATTACCTTCAGGTTACTGCTAGAATTATTTATTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2377
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000009649 Essential Splice Site 618 668 16 18
Genomic Location (Zv9):
Chromosome 7 (position 54394259)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 52664250
GRCz11 7 52935375
KASP Assay ID:
554-3182.1 (used for ordering genotyping assays)
KASP Sequence:
TTGGGTCTCTGGATGAGCGAGGAACAGCTCAGCTGGACATTCTTGTGAAG[G/A]TAGGGTTAAATGTATTTTCATTTCATTTTTTTGTAAAACCTGCTTTGGTA
Long Flanking Sequence:
CACAATTCGATATCATATGGTTTATCAGCCCAGCCCTACTGCAAACCAATTATTTATGTTCAGTTTGCAGTTAATTATGAATATTTTAACAGAAAAAGAACAGTGTATGTATGAAAGTCTCAATATGTATATGTAAATTATTTTGACTTCTCCATTGCTCAGGTGGATGTTCTGGAGTCCCAGTTTTCTCAGCTTTTACAGCAGATCAACTCCACAAGAGATTTTGAAAGTATCCGACTGGCCCATGACCATTTCCTCAGCAATCTGCTGGCACAGTCTTTTATTCTACTCAAACCTGTGAGTCTCTAGCACAAACTCTTTAACTCATTTCAACCAGGGTGTATTCTGCATTTGGTTAAGTCATAATTTGATTTCTCTTGCAGGTGTTCCACTGTCTGAATGAAATTTTGGATCTTTGTCACAACTTTTGTTCTTTGGTCAGTCAGAATCTTGGGTCTCTGGATGAGCGAGGAACAGCTCAGCTGGACATTCTTGTGAAG[G/A]TAGGGTTAAATGTATTTTCATTTCATTTTTTTGTAAAACCTGCTTTGGTATAGCTTAATTATGACACAAATACTAGTAACAGACAGCCTTAATTGCAAAAAAATATATATATACTAAATTGAGAATGACAGAATATCGAACAGAAGTCATAATTATGACATAGTGAAAGTTAATTAGATCCACACAGAAATTGGCTGATTTTTAGGCCATTGAGTCTTTTTTTTTTCTTTATGTAAACCAGGGTATCTTAAAGTCTTAAATCTCAAAAGCTAAATTTTAGGCCTTAAAGTCTTAAATCTACTGAAATGTTGTGTTGTAGGTCTGAAATCTTTTTTTAACAGGTCTTAATTTTCCTTTTATCTATATAGCTACCCATTCTGGCCATTAACACCCATACAATCCCAATAAAACTTTTAATTTAAAAACGGCATTACCTTGCAGTAACATTTGTTTAAAAATTCTACATTTATTTACTGCTGAGGATACTGACCTGACCTACA
Associated Phenotype:
Not determined