Busch Lab

ZMP

tyro3

Ensembl ID:
ENSDARG00000005356
ZFIN ID:
ZDB-GENE-990714-13
Description:
Tyrosine-protein kinase receptor TYRO3 [Source:UniProtKB/Swiss-Prot;Acc:Q9YI66]
Human Orthologue:
TYRO3
Human Description:
TYRO3 protein tyrosine kinase [Source:HGNC Symbol;Acc:12446]
Mouse Orthologue:
Tyro3
Mouse Description:
TYRO3 protein tyrosine kinase 3 Gene [Source:MGI Symbol;Acc:MGI:104294]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa5899 Nonsense Mutation detected in F1 DNA Not yet available
sa28813 Nonsense Mutation detected in F1 DNA Not yet available
sa36334 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa5899
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000040431 Nonsense 722 868 18 19
ENSDART00000081659 None None 691 19 20
ENSDART00000140391 Nonsense 722 868 18 19
Genomic Location (Zv9):
Chromosome 17 (position 10049211)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 10396113
GRCz11 17 10552147
KASP Assay ID:
554-3877.1 (used for ordering genotyping assays)
KASP Sequence:
CTTACCCAGGAGTGGAGAACTCWGAGATCTACGAGTATCTTATCAAGGGA[G/T]AAAGACTAAAGCAGCCGCCGGACTGCCCTSCTGACATGTACGTTTTAATT
Long Flanking Sequence:
TTCAAACCCTGCAATTTTTACAGCGTATAAGAGACTTTCTGTAGCTTTGTTTACCAAACAAGTGGTTCGAATTGGATTTTGATTGTAAACCTTTAATAAAAATGTACCTAGTTTTCTATTTTATGTGTTAGGATTTCAACTTCTTCAAAATCTCTCTGTAAATTTACAGATTTTATTTATTTATATATTTATTTATTTGTTTTACAAAATTATGTGTAGAAATACCAAAAAAGTCTGAGATTCTGTTTGGTCCTAGTCATTACATTACATTACATTACAATTTTTGACAACAGAATCTAGTATATTAGACAGCTATGTAATAGTCTATTATACTAGGTTTTGTAATATGTTTAGCCTTTGTTACTGACCTGTCTTGTGTTTTTTTTTTTTTTTGTTTAAAGTGGGCGTTTGGTGTGACTATGTGGGAGATCATGACTAGAGGTCAAACACCTTACCCAGGAGTGGAGAACTCTGAGATCTACGAGTATCTTATCAAGGGA[G/T]AAAGACTAAAGCAGCCGCCGGACTGCCCTGCTGACATGTACGTTTTAATTGTTGGGGTTTGTAAAATATCCCAAATTTTTTTTTAAGAGTTTTTTTTTTGGGTTTAACTTAATTGTTTTATGTTCAATTCACTTAATTTAGTAAAAGCTAATAAGTTAACTTGGTTCCTTCATGTTACACCAACACAAATCGATTGTGTGGAACCCCACATTTTTACAGTGGTCCTTAAAACCACAAAATATTTTGATGCTCATTGATCCACTTGACCAACTATCCCACATTTTCTCCCTTTCAGTTACGAAATCATGCACAGCTGTTGGTCTCCAGTGCCTAAATGCCGCCCCAGTTTCCAGCACCTCATTGACCAATTGGAGCTCCTGTGGGCGAAGTTGAATCCTGCTCCTGTAAAAGAGCCATTGCTGTATGTCAACCTTGAGGAGGAAGATGGAGAACAGGCTAATAGCGGGACCCGGAGCAGTGAGGAGCCCTCATGGGGCGTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa28813
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000040431 Nonsense 766 868 19 19
ENSDART00000081659 None None 691 20 20
ENSDART00000140391 Nonsense 766 868 19 19
Genomic Location (Zv9):
Chromosome 17 (position 10048820)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 10396504
GRCz11 17 10552538
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCCCAGTTTCCAGCACCTCATTGACCAATTGGAGCTCCTGTGGGCGAAGT[T/A]GAATCCTGCTCCTGTAAAAGAGCCATTGCTGTATGTCAACCTTGAGGAGG
Long Flanking Sequence:
TTGTTTAAAGTGGGCGTTTGGTGTGACTATGTGGGAGATCATGACTAGAGGTCAAACACCTTACCCAGGAGTGGAGAACTCTGAGATCTACGAGTATCTTATCAAGGGAGAAAGACTAAAGCAGCCGCCGGACTGCCCTGCTGACATGTACGTTTTAATTGTTGGGGTTTGTAAAATATCCCAAATTTTTTTTTAAGAGTTTTTTTTTTGGGTTTAACTTAATTGTTTTATGTTCAATTCACTTAATTTAGTAAAAGCTAATAAGTTAACTTGGTTCCTTCATGTTACACCAACACAAATCGATTGTGTGGAACCCCACATTTTTACAGTGGTCCTTAAAACCACAAAATATTTTGATGCTCATTGATCCACTTGACCAACTATCCCACATTTTCTCCCTTTCAGTTACGAAATCATGCACAGCTGTTGGTCTCCAGTGCCTAAATGCCGCCCCAGTTTCCAGCACCTCATTGACCAATTGGAGCTCCTGTGGGCGAAGT[T/A]GAATCCTGCTCCTGTAAAAGAGCCATTGCTGTATGTCAACCTTGAGGAGGAAGATGGAGAACAGGCTAATAGCGGGACCCGGAGCAGTGAGGAGCCCTCATGGGGCGTCCCGTGGCAGTGTGCAGGTATTGAGGAAGACGAAAAAGATTGGTTAATGGTGTCATCGGGAGCTGCTCTTGCTATTGGTGGAGATTACCGGTACATCATTGGCCCGTCTGTTAGCGCCATTGATGAAGAGAGCAGACATTCTGACGACGGACTATCGGAGGATATCAGGGAAGAAGAAGAGGATGTTATTATTAATGTGTGATTTATACTGTTGAAGTCTGAATTATTAGCCCACCTGTTTATTTTTCCCCTAATTTCTGTTTAACAGAGAGGAGATTTCTACAACACATTTCTAAATATGATAGTTTTAATAACTGATTTCTTTTATCTTTGCCATGATGACAGTACATCATATTTGACTAGATATTTTTCAGGATACTAGTATTCAGCTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36334
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000040431 Nonsense 787 868 19 19
ENSDART00000081659 None None 691 20 20
ENSDART00000140391 Nonsense 787 868 19 19
Genomic Location (Zv9):
Chromosome 17 (position 10048758)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 10396566
GRCz11 17 10552600
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGTAAAAGAGCCATTGCTGTATGTCAACCTTGAGGAGGAAGATGGAGAA[C/T]AGGCTAATAGCGGGACCCGGAGCAGTGAGGAGCCCTCATGGGGCGTCCCG
Long Flanking Sequence:
ACCCAGGAGTGGAGAACTCTGAGATCTACGAGTATCTTATCAAGGGAGAAAGACTAAAGCAGCCGCCGGACTGCCCTGCTGACATGTACGTTTTAATTGTTGGGGTTTGTAAAATATCCCAAATTTTTTTTTAAGAGTTTTTTTTTTGGGTTTAACTTAATTGTTTTATGTTCAATTCACTTAATTTAGTAAAAGCTAATAAGTTAACTTGGTTCCTTCATGTTACACCAACACAAATCGATTGTGTGGAACCCCACATTTTTACAGTGGTCCTTAAAACCACAAAATATTTTGATGCTCATTGATCCACTTGACCAACTATCCCACATTTTCTCCCTTTCAGTTACGAAATCATGCACAGCTGTTGGTCTCCAGTGCCTAAATGCCGCCCCAGTTTCCAGCACCTCATTGACCAATTGGAGCTCCTGTGGGCGAAGTTGAATCCTGCTCCTGTAAAAGAGCCATTGCTGTATGTCAACCTTGAGGAGGAAGATGGAGAA[C/T]AGGCTAATAGCGGGACCCGGAGCAGTGAGGAGCCCTCATGGGGCGTCCCGTGGCAGTGTGCAGGTATTGAGGAAGACGAAAAAGATTGGTTAATGGTGTCATCGGGAGCTGCTCTTGCTATTGGTGGAGATTACCGGTACATCATTGGCCCGTCTGTTAGCGCCATTGATGAAGAGAGCAGACATTCTGACGACGGACTATCGGAGGATATCAGGGAAGAAGAAGAGGATGTTATTATTAATGTGTGATTTATACTGTTGAAGTCTGAATTATTAGCCCACCTGTTTATTTTTCCCCTAATTTCTGTTTAACAGAGAGGAGATTTCTACAACACATTTCTAAATATGATAGTTTTAATAACTGATTTCTTTTATCTTTGCCATGATGACAGTACATCATATTTGACTAGATATTTTTCAGGATACTAGTATTCAGCTTAAAGTGCATTTAGGGGGCTTTCACACCTGCCTTATTTAGTTCGATTGAATCGCACTAGAGTT
Associated Phenotype:
Not determined