ZMP
grna
Ensembl ID:
ZFIN ID:
Description:
granulin-a [Source:RefSeq peptide;Acc:NP_001001949]
Human Orthologue:
GRN
Human Description:
granulin [Source:HGNC Symbol;Acc:4601]
Mouse Orthologue:
Grn
Mouse Description:
granulin Gene [Source:MGI Symbol;Acc:MGI:95832]
Alleles
There are 5 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa33188 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa38396 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa6034 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa20026 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa33188
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000103523 | Essential Splice Site | 92 | 873 | 3 | 19 |
| ENSDART00000137973 | Essential Splice Site | 92 | 1049 | 4 | 24 |
| ENSDART00000147732 | Essential Splice Site | 92 | 873 | 4 | 20 |
Genomic Location (Zv9):
Chromosome 3 (position 30084140)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 29802179 |
| GRCz11 | 3 | 29933021 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACAGCCATTGGCAGACAGGACACTAGCTAAAAAGCCAGACCTTCCCAAA[G/A]TGAGACATTATATAAAGAGTGTAAGTGATAGTACTCATAGCTGATCGTCA
Long Flanking Sequence:
AAAGCAGAAGTTGCAATTGTTAACACTGTAGGACAGGGGTCACCAATCTCGGTCCTGGATGGCCGGTGTGCCTGCAGGGTTTAGCTCCTCTTGCCTCAACACACCTGCCTGGGTTTTTCAAGTATAGTTAGTAAGACCTTGATTAGCCTGTTCATGTTTAATTAGGATTAAAGCTAAATTTTTCAGGACACTGGCCCTCCAGGAACAAGTTTGGTGACCCCTGCTATAGGACATTTATGTTGGCCACCACAAGGAAGTTTTAGATATTAGGTGATAGAACATATGATTTGCACTATTTATAAGCCCATATGGCTATAGGAAGCTATCTTAATGAAGTAAAACATGCCTGTGTGTGTTTGCAGGGAGAATGTTGTGAGGACCATCTGCACTGCTGTCCTGAAGGCATGTTGTGCAGTGTTAAGGACTTAACATGTACAAACGCAACACATACACAGCCATTGGCAGACAGGACACTAGCTAAAAAGCCAGACCTTCCCAAA[G/A]TGAGACATTATATAAAGAGTGTAAGTGATAGTACTCATAGCTGATCGTCATGCTCTAATAATAACCGCTGTTACTTAGTCATTCAGAATGATCTTCTCAATGCCTGCAAGTGAAAGCGACATCACCTGTCCTGACGGCTCCTCCTGTCCTGCTGAGTTCTCTTGTCTGCTGATGTCTACATCATACGGCTGCTGTCCAGTAGCACAGGTAAGCGACACTATTACAGGAATATCAGCCCAAAACACCAGCTACTGCTGTTGTAAATGGTGTACTGAATGGCCACAAATCGATGATAAAAAACACAATCCCTTAATAGCGTAGTTCAAAAATTCTGTCATCATTTCTTTGCCTTTTATTTTGTTTTATTTAGTTTTTTATTATATTTCAGTTGAACACAAAATAAGACATTTTGATGGTAAAATGCTGGTATCTGGCACCCATTGACTTCCATAATATTTTATTTTCTTACTATGGTAAACAACAGGTGTGCGCAAACAGAG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa38396
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000103523 | Essential Splice Site | 135 | 873 | 4 | 19 |
| ENSDART00000137973 | Essential Splice Site | 135 | 1049 | 5 | 24 |
| ENSDART00000147732 | Essential Splice Site | 135 | 873 | 5 | 20 |
Genomic Location (Zv9):
Chromosome 3 (position 30083931)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 29801970 |
| GRCz11 | 3 | 29932812 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTCTTGTCTGCTGATGTCTACATCATACGGCTGCTGTCCAGTAGCACAGG[T/A]AAGCGACACTATTACAGGAATATCAGCCCAAAACACCAGCTACTGCTGTT
Long Flanking Sequence:
TTTGGTGACCCCTGCTATAGGACATTTATGTTGGCCACCACAAGGAAGTTTTAGATATTAGGTGATAGAACATATGATTTGCACTATTTATAAGCCCATATGGCTATAGGAAGCTATCTTAATGAAGTAAAACATGCCTGTGTGTGTTTGCAGGGAGAATGTTGTGAGGACCATCTGCACTGCTGTCCTGAAGGCATGTTGTGCAGTGTTAAGGACTTAACATGTACAAACGCAACACATACACAGCCATTGGCAGACAGGACACTAGCTAAAAAGCCAGACCTTCCCAAAGTGAGACATTATATAAAGAGTGTAAGTGATAGTACTCATAGCTGATCGTCATGCTCTAATAATAACCGCTGTTACTTAGTCATTCAGAATGATCTTCTCAATGCCTGCAAGTGAAAGCGACATCACCTGTCCTGACGGCTCCTCCTGTCCTGCTGAGTTCTCTTGTCTGCTGATGTCTACATCATACGGCTGCTGTCCAGTAGCACAGG[T/A]AAGCGACACTATTACAGGAATATCAGCCCAAAACACCAGCTACTGCTGTTGTAAATGGTGTACTGAATGGCCACAAATCGATGATAAAAAACACAATCCCTTAATAGCGTAGTTCAAAAATTCTGTCATCATTTCTTTGCCTTTTATTTTGTTTTATTTAGTTTTTTATTATATTTCAGTTGAACACAAAATAAGACATTTTGATGGTAAAATGCTGGTATCTGGCACCCATTGACTTCCATAATATTTTATTTTCTTACTATGGTAAACAACAGGTGTGCGCAAACAGAGTTTTTCAGAATATCTTCTTTTGTGTTCAACAGAAGAAAGAAACCCATAAAGGTTTAAATCCACATGAGGGAGGTCAATTTCATTTTTGGAGTGAGCTATCCCTTTAAACTAGTCTCATCCATATTAAAATATTTAATTCTACTCTCAATGTGCAAATAAAATACCTCAGATGAGAAGCAGCAGCTCATTTCCATAAAAGATTGATCTAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa6034
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000103523 | Nonsense | 716 | 873 | 17 | 19 |
| ENSDART00000137973 | Nonsense | 892 | 1049 | 22 | 24 |
| ENSDART00000147732 | Nonsense | 716 | 873 | 18 | 20 |
Genomic Location (Zv9):
Chromosome 3 (position 30068401)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 29786440 |
| GRCz11 | 3 | 29917282 |
KASP Assay ID:
554-3919.1 (used for ordering genotyping assays)
KASP Sequence:
AAAGCACACCAGCTCCAAAGTTGGATCTCGGCGTTGTTAAATGCGATGAA[C/T]AGTCGAGTTGCTCTGCAGATTCGACCTGCTGCCTCTTGTCTAAAGAMGAA
Long Flanking Sequence:
TGAAATCATTCAGTGTAGTGATATGGAAATGTGGTCAAAACATGCCTGGAACTACTTTAGCTTAGCGGTTCACTGAAAATATAGGCAGACCTTACAAAGTTTATCAGCCAATCAGAATCAATCATTTGGCTGACCCTTGTATAAGACCAAATAAATGCAGCTTTGGTGAGAATAATGACTTCTTAAGAAGACATTAAAAAATCCTATCACAGTCTTTTTGAACGGTGTGCGTTTGTGTTAGTAAATCGAAACAAATACAATATTAAATTAGCTTAATGTTTCATGCAAAATGGTTTGTTTTTATAATGACACTATTTCTTGTTCTTCCTCAGGCTGTATGTTGCACAGATGGAGAGCACTGCTGTCCGGCCCACTATAAGTGTAACCTGAGCAGTGTGTCTTGTATTAAGGGAGACGTGGTGATCCCCTGGTACAATAAAATCGCTGCTGAAAGCACACCAGCTCCAAAGTTGGATCTCGGCGTTGTTAAATGCGATGAA[C/T]AGTCGAGTTGCTCTGCAGATTCGACCTGCTGCCTCTTGTCTAAAGACGAAACGGGCTGCTGCCCTTTTCCTGAGGTAAAAATCTGTGATTATGTCATGTGTGTATATTTATTCCTGTTCAATATATTTAATACACCTCATGTATGCCGTAGGCTGTTTGCTGCCCAGACCAGAAGCACTGCTGTCCTGAGGGCTACAGATGTGACCTGCGCAGACGCTCCTGTGTAAAGACCACTAGGCTGTACGTGGAAATTACTCAACTCACTCACATCCGCAGCAACAAGCCCCAGCCAAGTGTTGTAGTGAAGGACGTTCAGTGTGGTGGTGGATTCAGCTGTCATGATGGTGAGACCTGCTGTCTAACCTCACAAACCACATGGGGATGTTGCCCTTCTCCAAAGGTAAGGGATAAAGCGCTCTATTTCTAAAATTCACATCATTATTTTGCATTTAACAAATAAATGTAATTTTATCATCATTTAAGGAGCAAAAACTACTTTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa20026
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000103523 | Nonsense | 846 | 873 | 19 | 19 |
| ENSDART00000137973 | Nonsense | 1022 | 1049 | 24 | 24 |
| ENSDART00000147732 | Nonsense | 846 | 873 | 20 | 20 |
Genomic Location (Zv9):
Chromosome 3 (position 30066460)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 29784499 |
| GRCz11 | 3 | 29915341 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATGCAACACTGCTGTCCCGCGGGGTATAAGTGTGGGCCGGGTGGCACCTG[T/A]ATTTCAGCCGGAGACTTGGACTGGAGCAACTGGGTCAACTGGAAGTTGTT
Long Flanking Sequence:
TATAATGAAAGTCAGTGGCGTCTAATACTGTAGTACACCCATTACTGTTATTACATGAAAACAAACATTCTTCACAATATCTTCATGTTTTGTGTCAACTTGAAGTATTACATTTCTGAGTGAACACTGTAATGTTGACATAAAACAGTGTTCAGTTATTTGTGGAACTTATGGTCGTGGTTAAATGAGAAATGAATCTGTCTTCTAAACAGTTATTAACTTCATTTAAAGATGCCAATTGGCAAAAAAAGAGGCCACGTCAGAGAAGGAATATCTCTAGACTGCATGAATGGAAATGAGCACTTGTCTTCTGATCTCAGTTCTATTGACTTTACTCTACATTCAAATGGCAGGCAAACTGTACGTGTCTATCTCAGTCAAATGGCTGTTCCTAACTCTATCCTCGGCTTTGTATTCTGTCTCTCTGTGAAGGCGGTGTGCTGTGATGATATGCAACACTGCTGTCCCGCGGGGTATAAGTGTGGGCCGGGTGGCACCTG[T/A]ATTTCAGCCGGAGACTTGGACTGGAGCAACTGGGTCAACTGGAAGTTGTTCTTCTCCAAAAAGAAACGAGCCCTAACTCTATAAACATCACAGCAGCACATTGATTTTTACCAAAGACACTTACATGCTCAAGTGTCTGATATTTTTTTTCACATTTTACATTCCTCAATGTACTAATCAGTGATAATCAGATGATTAATTTCACATGGTTGATTTTATTTGCAGAAGAAAATGTTTAATAAGGACTCATTTTGGTAAGTTTCCATTGTCTAAAAGGTAATACCAACTACGCTTTAGTCAGAAAGTATGTGTCATTTTTGTAAAGTGTGTTCATAAAATGACCATCGTTACTGCTTAGTGCTGAGGATTTATTTATTTCCTAAATTGTGTAAAAATGTAACATATTAAAGCGTAGATGACCTCTAGTGGCATATCTTTCATTATAACTCGCATGTGGAAATGTCAGGTTTATAGGTTACATTATTTCAGACTTGACATCA
Associated Phenotype:
Not determined