Busch Lab

ZMP

lonp2

Ensembl ID:
ENSDARG00000004896
ZFIN ID:
ZDB-GENE-041212-1
Description:
Lon protease homolog 2, peroxisomal [Source:UniProtKB/Swiss-Prot;Acc:Q5PQY6]
Human Orthologue:
LONP2
Human Description:
lon peptidase 2, peroxisomal [Source:HGNC Symbol;Acc:20598]
Mouse Orthologue:
Lonp2
Mouse Description:
lon peptidase 2, peroxisomal Gene [Source:MGI Symbol;Acc:MGI:1914137]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa36621 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa13813 Nonsense Available for shipment Available now
sa29014 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa36621
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000027791 None None 840 None 15
ENSDART00000028806 Essential Splice Site 241 840 4 15
Genomic Location (Zv9):
Chromosome 18 (position 18300397)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 18528979
GRCz11 18 18518045
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAAGTTGCTTCAAAAGACCCGCAAACTCAGACCGGATGATGACAAAAGAG[T/C]AGGACAACATAAAAATTAGCACAGACAAACTCATCCACAGCTTCCTGTTT
Long Flanking Sequence:
TTTGTTAAACAATAAGTTAATTTGAAAAATGTTGGAACCCTGTAACCATTGACCTCCATTGTGTTTATTTTGTATTAATTTTTCAATAATAATTAATGATTTCCAAAGTAAAAAAAAAAACATGGCATCTTTGTGTTCAACATAAAAAAAATCTAACAAAAAGGTTTGTTAGCACTTGAGGGTGAGTAGATATTTTATAAAGTATGTATAAAGTACATTTTCATTTTTAGATTAACTATCCCTTTAATTTTTTTTTTGGTTTATTCAGAGGTTGTCCTTACGATAGCCTTGTTGCTGGCATGGTGTAAAAAGTAAATAGAAATGAAAAAAAAAAGTTAAATAGTTTCAAAAAACTTAATGTTGGTGTTGATGGCAGGTTCTAGATGCAGTAGACTTGGAGGAACGCTTTAAGAAGGCCCTTCCGCTGCTCACCAGACAGATTGAGGGCCTCAAGTTGCTTCAAAAGACCCGCAAACTCAGACCGGATGATGACAAAAGAG[T/C]AGGACAACATAAAAATTAGCACAGACAAACTCATCCACAGCTTCCTGTTTGAGTCACAGTTTTGTTTGGTTTCTCCTAGGTTCTGTCCATCCGTAAAGGTGGTGTGTTCCCCGGTCGCCAGTTCTCTCTAGATGAAGAGGTGGAGGATGAGGACAGTGATGACACTGCTCTGCTGGAGAGAAAGGTGAAGGCAGCTGCTATGCCTGAGGCAGCTCTGCGCGTCTGTCTCAAAGAGCTCAGACGGTGTGTAATGCTCATTTTACAGCTAATCATGTTCATATTTTAGCTGCATTTTAAATAGTAAGGGACTTGTCATTTTATCTGTAGTTTTTAGATCTTCAAGAGTGTCTAATTATCCTCCTGGAAGGCAGATGTTTTATAAATCTAGATCCAGCCAATTCCAAAACACATGCCTAGAAGTTTTCAGGGAGTCTAAAGAGACCTTAGTTAGCTTAATCAGTCAGCTTAATCTAAACTCTGTAGGGCAGTAACCCTTCTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13813
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000027791 Nonsense 565 840 11 15
ENSDART00000028806 Nonsense 565 840 11 15
Genomic Location (Zv9):
Chromosome 18 (position 18153799)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 18505565
GRCz11 18 18494631
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTCTTGCGTGTGTKTGCAGGTACACACGGGARGCTGGCGTTCGCTCTCTG[G/T]AGAGGAAGATCGGGGCTGTCTGTCGAGCYGTGGCTGTGAAGGTTGCTGAA
Long Flanking Sequence:
GGGCTTTTCATTTTCAGTCAGCCAGCTCAAGTGCTTCCGGCATTTAAGTTTAAGTTCTAGTTTCTTTAAAAATCAATGATTTTCTCTACCTGATTGATATACGATATAAAGTGGGTCTCAAAACGGACAAGAAGCACTGCATTAAACTCAATTGTTTATCTATTGCATGTGTTTAAAATATAGAAATGTATTTTTAGTGCTCCTGATGTTTCTGACAATGATTAATTTAAACAGCCTTTCATCTTGTTTAATACTTGAACAGCTAAATGAAAGCCTAAGTCTATTAATAAGATTATATTTAAATTAATTTACATCCTCTATGCTGTAAAAGCAAGCTTATGAAATTAAAAATGGTCACATCAGCCTTCCAGGTTTTATAGTTTTTTTTTATCACAGGAAGCTATTTCTCGTCCTGAGCAGAATTTATAAGATACTGATGTTGTAAGAACTTTCTTGCGTGTGTTTGCAGGTACACACGGGAGGCTGGCGTTCGCTCTCTG[G/T]AGAGGAAGATCGGGGCTGTCTGTCGAGCTGTGGCTGTGAAGGTTGCTGAAGGTCAGAAGGTCTCTAGATCAGAGGCGCCCACTGAGCAGCATGCTGGTAAGACTGTTTTCATGTCATGTTATTTACTGCTAGATTTACTCCAGCTCTGCTCCAGGATTATTGCTAGTAGTCTTTGAGCAAAGATAACTTACACGCTGGGTTTTCTTATTTATGTAGTATCCTGATGGCAAGATCTCATTGGATGAAAATACTGTCACTGCATTTTAAAAGAATAATACTTTATGAAGTATTTTGTTTTCAGAATAGGAAAAATCTGTTAGTATATTGAAATAAATATTAAGTTAAATGAAAATATTTTTTACCTATAAATTGTTTTTATTTAATAAAAAATATATACATTTGGAATTGAAATTAATATTAAGTCAAATGAAATTGTATTTTTCATCTTCAAAAATGTTTGATTTTATAAAAGAAAATATAATTTTGTTCAGTGTACTATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa29014
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000027791 Nonsense 614 840 12 15
ENSDART00000028806 Nonsense 614 840 12 15
Genomic Location (Zv9):
Chromosome 18 (position 18146595)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 18498361
GRCz11 18 18487427
KASP Assay ID:
2261-2064.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCAGAATACAGACAGTAAGGTGGAGGATTCTGGGATTGCAGCACCTCCT[G/T]AAATGCCAATTGTCATTGACCACATTGCCCTGAAGGATATTCTTGGACCG
Long Flanking Sequence:
TAAAGTCAATTCACCCTGAAGCTGCTTCCGTTATAATGTTTGATATTAAAACCCATAATACCTTATTGTTTCCTCCCAAAATGAAGACAGCACCTGCTCTCCCCCTTCACTGGACCCCTATGGCATTTTCTCTCCAGCCTATAATTCTCCATTATTCCAGACAGCTCTCTTTCTCGCCTTTGCTTTCTTTTCACTTTTCCCCCCTCTGGCCTCGATGTCTGTCACCTTGCTTAATGAAAAGCTTCAAATAGACGTGATAATGGAAGTGCAGACCTGATCAAATTTTATAGCGCCATTTGTCTCTTGTAATTCACTTTCCTTTTTTTTGCATCTCCGCTTAAATGGACTTTACTTTTAAGTTTGTGAAATGTCAGTCACCCACCTCTTTTATATCGACACAAGTTTTAAACAAATAAAACCCACCTGTACTTTTCTGTTTGTACATTTCAGAGCAGAATACAGACAGTAAGGTGGAGGATTCTGGGATTGCAGCACCTCCT[G/T]AAATGCCAATTGTCATTGACCACATTGCCCTGAAGGATATTCTTGGACCGCCTCTCTTTGAAATGGAGGTTAGCATCACTGAAATGCCTGAAAGCTCATTATGTCTCAAATACATATAGAAAAAAAGGATCAGGGTCTAATAAAATGAAGGGTGGTTATTTATTTTACAGTCCTATTTTACCTGTACTAACTATGTATTTATCATAGTCATCATTACATAAACCTAACCATGAACCTAACCTTACCCATGTAATTACTATTATAACCCAATTTTTTTTTTTTTTTTTAGATATAGTTCATGACAAAACTTTTAGCCCTTAAATTTAAATTCTTTTTCAGTTATTTCCCAGGTGCTGTTAAATGGAGTGAATTAAATAAAATAAAAAAAGTTTATTTTTTGTCTTTGCCGTGATGACTGCACAAAAGATTTGGTTAGCTATTTTGCAAGATAGTTTTCAGTTCAAAGTATGATTTCAATGCCTGACTAGTTTAATTGGGTT
Associated Phenotype:
Not determined