Busch Lab

ZMP

casp9

Ensembl ID:
ENSDARG00000004325
ZFIN ID:
ZDB-GENE-030825-5
Description:
caspase 9, apoptosis-related cysteine protease [Source:RefSeq peptide;Acc:NP_001007405]
Human Orthologue:
CASP9
Human Description:
caspase 9, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1511]
Mouse Orthologue:
Casp9
Mouse Description:
caspase 9 Gene [Source:MGI Symbol;Acc:MGI:1277950]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa11164 Essential Splice Site Available for shipment Available now
sa37709 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa37710 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa11164
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047020 Essential Splice Site 146 436 3 10

The following transcripts of ENSDARG00000004325 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 25264722)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 25050842
GRCz11 23 24977383
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTACCACTGAGACCTGAAAGCCTGCCGGTGCACAAGACATATAGTCCACG[T/C]AAGTCACTAGCTTTATAAGTTTCTGTTTTAATTTAAACAGNNNNNNNNNN
Long Flanking Sequence:
TACACTGCATTGCAAATTTCATGTAAAACTTTTTTTCTAACAGAGCAAGGCAACCAGACGTGACCAAGCCAGGCAACTGGTGAAAGACCTGGAGACGAGAGGAAGTCTTGCTTTCCCAGCCTTTCTTGATTCCCTGCGTGAGACTGGCCACAATGATCTTGCAGAGCTCCTTCAAAGCGGAGATGGTGTTCATCGCCCTCCTGTCATTTCTGTACAGCCTTCACCGATCCCTCTGCCAGTCCGTAAGTGTGTTTTTCCATCAGTAACACAGGATTTACTTGGATATAGATATGCTCCTGTAATACGAACTTAAAACACCCTTATCTGACCATCATCCTCTTGAGCCGTAGCCGTAACTGGCAATCATCTTGTCTGATCTTATGATTCAATGCAGAAAATCTAAATCATACTGAAAAGCCAGACAAACCTGATATCGCTTCTCCACGATTAGTACCACTGAGACCTGAAAGCCTGCCGGTGCACAAGACATATAGTCCACG[T/C]AAGTCACTAGCTTTATAAGTTTCTGTTTTAATTTAAACAGAGTAGTTTATACTAGACATTTAGTACAAATAATGCTTGTATATACTGCTTATAAAGCATGAATTTGCACTTTTTATTTTTTTGCATTTCTACAGCTTCTGAAACTGTGGTGAGACCAACCAGGCCAAGACGTGACAGTATACAGGTAATCCCTTACAACCTCAACTAAAAAAATAAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATACTGCTTCTTCAACAGACATTTAACTGACTATATGAAACTTTGCAAGTACATGACAACTTACACTAACCCCAACCCAAACCTAACAGTCTACTCATAATCTATTGAGAATTAGTTGGCACGTAGATGCAATGTAACTCATATTCAACAAAATGCATTAAAGAGACCATTAAAATAAAGTGATACCAAGCATATATATACATATAATTTTCAACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37709
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047020 Essential Splice Site 163 436 5 10

The following transcripts of ENSDARG00000004325 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 25267092)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 25053212
GRCz11 23 24979753
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATTTTCTTTTCGGCTTAGTCCCTTATTAATCTGGGGTTAATATTTTTTC[A/T]GTGCTACAAGATGGATGCCAGTCCGTGTGGGGTCTGCTTGATCATAAACA
Long Flanking Sequence:
AATGTCTGATTTTTCCAATATCGTGCAGCCCTAGTATCTAATGATTAGATACTAGTATCTAGTGAATAAGTTTTACCGTCTATTTAATAGTTACAGTACAGTATCTAAGAAAATAAGACCTTAAGTACCTTAAGTTCCCAGGTCGTGATGTACAGTATAAGACAATAGCATATATCATTGTATAATTTGTAAATTAAATGTGTGTAAAAACAGCTTTGCCATAGTCACTTTCTATAATTTTTATTGTTTATACTTTTCATTTTCCCCCATTCATATTTAATATACATATATAATTTGAATATTGTAATATTATAAAGAGTTGCATCATGAATTGGAGCACTTACAGGGGTTGGTAATGTAAATATTTCCATGTTATTCCATTGGGATGTTCTCAGTATTCACAAGGTCAAGTAGAATATCAAGTTGAGAGTAATTGTCCAAACATTCATTCATTTTCTTTTCGGCTTAGTCCCTTATTAATCTGGGGTTAATATTTTTTC[A/T]GTGCTACAAGATGGATGCCAGTCCGTGTGGGGTCTGCTTGATCATAAACAATATCAACTTTGAAAAAGCCTCTGAACTAAATGACCGCAAGGGCTCCAACATCGACTGCGACAAGCTGGAGAAAAGATTTAAAGCGCTCAACTTTGAGGTTACAGTAAAAAGGAACTTGAAATCTAAAGTAAGCTCAGTATTTCCTCTTTTTCTCTCTGTAAACACAGCTGCAAAATAAATATCCCTCGGTCATTAACAAGTTTTTTAGAAATTAATTGAAATGTTTTGCTCCGATATGTAGCGCATAAGGCACGAGATGGCATCTTTAGCGAAGAAAGATCACTCTACATACGACTGCTGTGTGGTCATCATCCTTTCACATGGCACTGAGGTAAAACAATTAGCTAAATGCTACATATAATATATTCTATATTTGAACACTATTAGTTGCTCAACAAAGAAGAACAACCTTCATTTGTTTGCATGAGCGGTTTTGATTGCTTCCTCAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37710
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047020 Nonsense 366 436 9 10

The following transcripts of ENSDARG00000004325 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 25271855)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 25057975
GRCz11 23 24984516
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATTTTTGAGTTCATATTAAATGGTGTGCATGATGATTTATTTGCAGGTTA[T/A]GTCTCCTGGAGGGACACAGAGGCCGGCTCTTGGTATGTGGAGAATCTTGA
Long Flanking Sequence:
CAGAAAAACTAATTAATCGTTAAATGATGACAATTTTGAGTATGTTAATAATCCTTTACTTATGTTTTTGGCAAAGACTGAAATCAACGTTTGAATGCAATGCCATTGGCTAGTGACATGCAACCCTCAAAAACATATTTGTCATCGAATGATTCATTTGAAATTGAAACATGATGTCTTTGAGTGTGTTACTGAATCATTCATTTAAAAAAATTGATAATTTAAGCTATATGATCATATAAACCACCATATGTAGCAGAGGCTCAGTCCCCTGTAGAATAAAAGCCTAGAACTATCTATGGTTCGAAACTTAAACATCGTTTTTGGCTTTAGAAAGAGAAACCATTTGCCAAACATGATTCAATAACATATTTGCATGCACATCTCAGAAAACCACCAAAAATCTTGTAGCCCAGTGGATTTTGTCAAATTTTAACACACTAATTTTGTATTTTTGAGTTCATATTAAATGGTGTGCATGATGATTTATTTGCAGGTTA[T/A]GTCTCCTGGAGGGACACAGAGGCCGGCTCTTGGTATGTGGAGAATCTTGATCGTGTGCTGGAGGAAAACGCTATCACAGATGATCTGGTGACCATGCTGATGTTGGTACGTCTTTGTCCTGTAAATCTTCTGAAGTTTGATTTATGTGATGGAAACTGCCACATATAGATGCATTATACAGTATATGCATCAATAATGATTAGAGCAATGTGTATATATTCTATACAGCTTTATACAATTATAAATAACTATGTAGCTTATTATTAATTGTGTAATTTTTCAATCTTACCTTGAGGTTTAAAGTCTGTGTGTATGAAAACAAAAAAACATTTATATTTTAAAATAAGTTTATTGAAGTAAAACAGACATTTTAGGTGCTGTGATAATAAAATAGTGCATAAAATAAGTGTACAGTGTTCATTAAATATCTTTTTTCTTTAGGTAAATGATGCAGTCTCACAAATATCTGCCAAAGGCCTGTATAAACAAATGCCTGGGTC
Associated Phenotype:
Not determined