ZMP
dennd5b
Ensembl ID:
ZFIN ID:
Description:
DENN domain-containing protein 5B [Source:UniProtKB/Swiss-Prot;Acc:Q6NXD8]
Human Orthologue:
DENND5B
Human Description:
DENN/MADD domain containing 5B [Source:HGNC Symbol;Acc:28338]
Mouse Orthologue:
Dennd5b
Mouse Description:
DENN/MADD domain containing 5B Gene [Source:MGI Symbol;Acc:MGI:2444273]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa31391 | Nonsense | Available for shipment | Available now |
| sa10610 | Essential Splice Site | Available for shipment | Available now |
| sa11630 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa31391
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000033053 | Nonsense | 555 | 1311 | 6 | 22 |
| ENSDART00000079461 | Nonsense | 555 | 1325 | 6 | 23 |
| ENSDART00000133837 | None | None | 152 | None | 5 |
| ENSDART00000140510 | Nonsense | 535 | 1291 | 5 | 21 |
| ENSDART00000141119 | None | None | 240 | None | 4 |
Genomic Location (Zv9):
Chromosome 4 (position 15740641)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 16683481 |
| GRCz11 | 4 | 16672457 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGCTGAGGGAGGTGTTCGCCGCACGCTTCGCAACGATGTTTGCAGACTA[C/A]GAGTCGTTTGTGATTCAGAACTCGCCAGATTTGGAGTCTTGGCTGACCAA
Long Flanking Sequence:
CTCCAGGCAAACCTGTGTTTCGTAGACATCGACAACCACTGCATCGAGCTTCCGGAAGACTTCCCTCAGTTTCCCAACAGGAGTGAGTTCATCCAGGAGCTGAGCGAGGTGCTGCTCAGTTTTGGCCAGTCTCCCGAAGGGGGTAGCAGCTCTCCTGAACCGGCCGTGATGAGCTTGCAGACCTCTGTGCTGGAGAAGGAGCTCAAGAGCACTTCGTTGAGAGAGTTGGTGGACGATAAGACGAACGGCAACCTCGGTGGAGAAGCGCTGGATGTGCTGGAGCTCCTGCAGGGCAACCCGACGCTGGAGCGCCTGCAGGCTTTGGCCAAGAGGACTGGGGTGAAAGTGGCCCGTCTGGAGGCGCTGGCAGCGGGACAGAAGGGGGATGAAGGTGTTGGAGGAAGGTCTCCTGTTGAGGAAGAGGAGCTGAGGAATGCTAAACTGAACGTTCAGCTGAGGGAGGTGTTCGCCGCACGCTTCGCAACGATGTTTGCAGACTA[C/A]GAGTCGTTTGTGATTCAGAACTCGCCAGATTTGGAGTCTTGGCTGACCAACAGAGAGCAAATGCACAACTTTGACAAGGTAACAAGGTTGTTATGCACTTTTTATACCTGGTGCAAGATGTGTTTGTGTCAGTGTTTTTATTATTATTATTTATAATGTGAGCATTATAAACTACCTTCATACACTCTGAAGTTCCCCACTGGTACAAATAAAGTGATTTGAATTTAGTTGAATTATATTGCAGAAAAAACACACATTTCAAATTAAAATGTTGTCTGCGGGGTCTTAAAATGTCTTAAATAATAATAAAAAAACATTTTAGGCCTTAAAAAGTCTTAAATTCACAGAAATATTGTGTTGTAGGCTTTAAATCATTTTAAACAGGTCATAATTTTAAACATTATCCAAGTAATGACCCAATTAGGCTTAAACCCATCCAATCACCAACAAACTATCTAAGTAATTTATATATACATGCAATATAACAGCAACTTGTATAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa10610
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000033053 | Essential Splice Site | 888 | 1311 | 13 | 22 |
| ENSDART00000079461 | Essential Splice Site | 888 | 1325 | 13 | 23 |
| ENSDART00000133837 | None | None | 152 | None | 5 |
| ENSDART00000140510 | Essential Splice Site | 868 | 1291 | 12 | 21 |
| ENSDART00000141119 | None | None | 240 | None | 4 |
Genomic Location (Zv9):
Chromosome 4 (position 15727817)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 16670657 |
| GRCz11 | 4 | 16659633 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCAGCGTTGGTCTTCCTGGATTACGTGTGTCCGTCATACAGGATATGAGG[T/A]TTGTTTATCACTKGATGGCGTATTACAGGGGTTTGGTTTTATAATAATTC
Long Flanking Sequence:
AGGTGCACAGAGCACAACGGCAAAAACACATATTGCTTAAGCAGTGAGCTAAACGCTTGCAGCCTTTAGAAAACCATTCAAAAAAGGCGCTTTTCATTACAATAAGCGTGTTCGGTATGATTGGCCCCTAAAACACTAATATTCTATAAAAAAAACTGTTCCCTTATGGTAATTTTGTTGTTTTTGAGAGCTTTCAGAGGCAGAAAACTCGCGTTGACACTCAGATTACCCAGATCAAGATTAAACAAATAAAAAAAGTGCATTCTAGTTATTTTTAGTTTTATTTACTGTTTTAATGACAAAAAATATTTAACCATTTTTTTAGCTGTAATTGTTCACAATGATATGCATATATAAACAGAAAGCCACAAGTTGTGGTTATGAATACTAAACCTGTTTTTTTTAATCCCGCCACAGTGTCTAATGGCCAGGAAAGACGGAAAACCGAGTCCAGCGTTGGTCTTCCTGGATTACGTGTGTCCGTCATACAGGATATGAGG[T/A]TTGTTTATCACTTGATGGCGTATTACAGGGGTTTGGTTTTATAATAATTCAGTTTGGTAACTTATAAGAGATGATAATGTTTAAAAATGTTTACATACACCAACAATGTTCACAATGTTTAAAAGGCTTGTGGCCTTTCAAATTCACATTGTTTTTCTATTTCTTAAACATACTTTCTGTGTCTCTTTTGACTTCTCAGACACATCCAGAACATGGCAGAGATTAAGACTGATGTAGGTCGAGCACGTGCCTGGATCCGTCTGTCTCTGGAGAAAAAACTGCTTTCCCAGCACCTCAAACAGCTGCTGTCAAACCAGGCCTTAACCAAGTATGTACCACACACTTTTGTGCACCTGCAAAATTACATTTCTGGCTTTTTAGCTTTTCATTTTTTTTTTTTTTTTGAGTTTAATGCAAAGGAAAATTATCTGAAATATACTTTTAAGTGCTACTTTTTTCACACTTTTTCAACTTGTGTCTGTAGATTTTTTTTTTAAAGC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa11630
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000033053 | Essential Splice Site | 972 | 1311 | 16 | 22 |
| ENSDART00000079461 | Essential Splice Site | 972 | 1325 | 16 | 23 |
| ENSDART00000133837 | Essential Splice Site | 28 | 152 | 2 | 5 |
| ENSDART00000140510 | Essential Splice Site | 952 | 1291 | 15 | 21 |
| ENSDART00000141119 | None | None | 240 | None | 4 |
Genomic Location (Zv9):
Chromosome 4 (position 15725955)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 16668795 |
| GRCz11 | 4 | 16657771 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTAACATTTTGTTTAGTTTCCACCTAATTTGTGTTGTTTTCGCATTGTAA[G/A]TGATCCCATACCGGGCTGTGAKCATCCCCATCAAGAAGCTGAGTAACGCC
Long Flanking Sequence:
TTGCGGGGTCTTAAAATGTCTTCATTCTTAAAAGTTAAATCTTAGGCTTTAAAATGTTTTAAATCTACTAAAATGTTGTGTTGCAGGTCTTAAATCTTTTTGAACAGGTCTAAATTTTCCTTTGTTTATGTATAGCTACCCAATTAAATTATCCTTAAACTAAACATTTCTCATTTCATTTTATTTACCTACGGAAACATAGTGTTGCAACCTTTGTTGCTGGATAATTATATGCCTAGAAATATATACGAATTGTGCTAAGAACATTGTATAAAAAACCCAGTGTCGTCACGTGTTATGTTTTAATTTTACCATTATTATGGTGAAGTAAACGGTTGTAGACTGACCTCCGCGTATAGCGTCTTTTTCCTCAAATTATTCAAGCTTTCACTTTCACATAGCAACTTGCAATATTTTTTATTGTTAATCATGAACTCACTTTGTTTTTGTGTAACATTTTGTTTAGTTTCCACCTAATTTGTGTTGTTTTCGCATTGTAA[G/A]TGATCCCATACCGGGCTGTGATCATCCCCATCAAGAAGCTGAGTAACGCCATGACCACGTCCAACCCCTGGCTGTGTGTGTCGGGCGAGCTGGGCGACTCCGGCATCCTGCAGATCACCAAAAACATACTGGAGATGACATTCGACGTGAGTTTCAGCTCAGAAACTGATACACGTTGCTTTATTTAGTTTTCCTGTGGGACTGAAACAATCACCCATCCTGTCTTCTGCAAATTTGAGCTTGTTTATGGCTCTTTCGAACACCTGCTTCATTGAAATGAGTTAAACTCAATCTATTAGGAAGTAGAATGAAAGTAACAATGTAATGATTACTAGTCTAAATGCTTGGCATAACTTCTGTTTAAGCATTCTAATTTATATTTCACTCCTTTCTTTTATTCTCAGTGCAAAAAATACAACATTTATAATGTTTTATTGTCTTACAGTTTTGGGTTTACTGAGATTTTTATGTTACAAATAAGAAATAAAGATCATATTAAC
Associated Phenotype:
Not determined