Busch Lab

ZMP

kdm5bb

Ensembl ID:
ENSDARG00000003098
ZFIN ID:
ZDB-GENE-030424-1
Description:
Lysine-specific demethylase 5B-B [Source:UniProtKB/Swiss-Prot;Acc:Q6IQX0]
Human Orthologue:
KDM5B
Human Description:
lysine (K)-specific demethylase 5B [Source:HGNC Symbol;Acc:18039]
Mouse Orthologue:
Kdm5b
Mouse Description:
lysine (K)-specific demethylase 5B Gene [Source:MGI Symbol;Acc:MGI:1922855]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa34426 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa45325 Nonsense Mutation detected in F1 DNA Not yet available
sa10483 Nonsense Available for shipment Available now
sa41230 Nonsense Mutation detected in F1 DNA Not yet available
sa11572 Nonsense Available for shipment Available now
sa14544 Nonsense Available for shipment Available now
sa21313 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa34426
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005583 Essential Splice Site 175 1522 4 28
ENSDART00000108508 Essential Splice Site 175 1503 4 27
Genomic Location (Zv9):
Chromosome 8 (position 29190701)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 28318619
GRCz11 8 28337758
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAGGATCCTGTACCCGTACAACCTCTTTCAGTCTGGGACAAATCTGCTGG[T/A]GAGTTTAACATGTAGATGTATCAGATCTATATATCACACACTTTACATAA
Long Flanking Sequence:
GGCTCAAACCAGAGTCAAACTCAACTTCTTGGATCAGATCGCCAAATTTTGGGATCTACAAGGATGCACGCTCAAAATTCCCCACGTGGAGAGGAAAATCCTCGATTTGTACCAGCTCAACAAAGTGAGCGACACTTACAGTCAGGTTTCAATGACAGACTGTACAAGTTGTGAGCCATTATGATTGCCAAAACCTGTTAACACATCTTTGTATGTGTCATTCATGTAACAGATGGACTCTTTATAGTTGATCAAAAGAAACAAAAGCATTGATGAATGTTTGTTATCTTTCTGTAATGAACTCCAACACTCTTTCTCAATCTGCCAGTTGGTTGCAGATGAGGGTGGGTTCGATTTAGTTTGTAGAGAGAGGAGATGGACCAAGATCGCCATGACGATGGGTTTTGCCCCAGGCAAAGCTGTGGGCTCCCACCTGAGAGCCCATTACGAGAGGATCCTGTACCCGTACAACCTCTTTCAGTCTGGGACAAATCTGCTGG[T/A]GAGTTTAACATGTAGATGTATCAGATCTATATATCACACACTTTACATAAAGCTTTCATGCAGGAATTCACAGCATGTGTATGGGCAGATTTTTGGGGGGTTGGAGATTGGTTACAGCTGGTCTCCAGTGTTAGAGCTGTGCCTCCGGGGTTAGCTGTATTAGGTCTCATTGAGCACACTGTGGTTTCTGCAGAATGGTATTAAGTGTTTTATCAACTGTCCATGTTTGTTTTCAGTTGTGTTACTGCTGTTTGTGCCACAGCCAGATGTGGTTATAAATGACTTGACATGGTGTAAAGATGAGTTTTAATCAACCTGATCACAAATGGATGAGGCTAAAGACAGGTGTGAACAGGATCTAAAATGTTTTAAACATTTGTGTTTTCAACTACCTACTGAGGTAGCTGAAAACACATTCATGATTGCTTTCATAGTGTAAACACTCATGTGGCTAAATGCTTTCACGCAACCACAAAAGACCTCCTACTTTCTGCCTACTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa45325
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005583 Nonsense 234 1522 6 28
ENSDART00000108508 Nonsense 215 1503 5 27
Genomic Location (Zv9):
Chromosome 8 (position 29186854)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 28314772
GRCz11 8 28333911
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGAGGCAAAATGTTCCACTTCAGCCTAGCAACACGAGCGCACCGGCTAGA[C/T]GAGCCAAGAGGATGAAAACAGAGGTGAATATAAACACATACGTATGCCAG
Long Flanking Sequence:
ACCCTTTTATAGCACATTAGCTTAGAGATATATACATAATATACTAATACTAACATCTAAAAACATTAATTTTGTTTTGCACATACTTTAAAATTAGTACAATTCATCTAAAACCTTATGAAAGCTTTTTATGAGGAAAAGGACAAAATTTAAATCTATATTTTTATGAAAACACTGACCTTTAAATTATACCCTAGACACATTGGTACTATGGAAAAGTTTAGCCATTATGCTCACTATCGCTTTTTGTGTTTAACTGGAAAGAATAAAGTCATACCGGGGTAAAACAACACGAGCTCAAGTAAAATATGACAGAGTAGACATTTTTCTAGGCTACCAACTCTTACTTACGGAGTGAGCCTTGTTCTTTTTTTTTTCTTTAGTGTCTGCAGAAGCCTGGGGATGAGGTGAATGACATTGACAAAGAGTATAAACCCCACGACCTACTGCAGAGGCAAAATGTTCCACTTCAGCCTAGCAACACGAGCGCACCGGCTAGA[C/T]GAGCCAAGAGGATGAAAACAGAGGTGAATATAAACACATACGTATGCCAGTTTTCTTAAAGTGTTGGTGAAGGAATTTATAATATGGTTTTGACTTTCTTTCCGATAACTTGTGCTAAATTAGGTGCATTCTTGTTCAATTAAATTGGTAGAAAAAAAAAACTGATATAAACACAATGAATTGTGTATAATAATTTGTGTCTCATTTTTTGCATCTGCAGTCTGGCTGTATTAAGTCAGAGGAAGGTGAGGGGGTTGAGAACAAGCCAAATCTCAGGAGGAGGATGGGTTCTTTCGTTGTCAAGACTGAACAAAGTGAGCATCTACCATTTGCGTCTAACGTCTGGCTCAGATCTTCTGTAGCCAGTAAAGCAAAGCAAACATGGGATTAGCATAGTTTTTTTAGTCAAATCAGATTCCTTGTATTAACAAATGTGTTTTTATTGTGTATTAGAAAAGGAGATCCCTATACAGGTGAAAGAGGAACCTGTGGAGATAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10483
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005583 Nonsense 315 1522 9 28
ENSDART00000108508 Nonsense 296 1503 8 27
Genomic Location (Zv9):
Chromosome 8 (position 29183696)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 28311614
GRCz11 8 28330753
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTATATATAAATATGKCATGTGATTTATYCGKCTATAGGTGGACCTCTA[T/A]GTGTGTTTAGTGTGTGGAAAGGGAAACGACGAGGATCGGTTGTTGCTATG
Long Flanking Sequence:
GCATAAATGTATGCCTATCTCTCATCCGTGTTGTTCAAAAAGCTTGTTGGTCAGCAAACAAAAGCGAAACCTATGCTTATTGGTTGTGATATAGCGAGTTTGAACCAATCTGGGCATGGAGGAGGGACAATGCATCAATATATCATGTCTGGTTTGTCCGGAGACACAGTGACGAGCGTTTCTTTGTCAAATCAGCGTTGTCAAATTTTGATGACGTAACCGCACTGATTTCGGAGCCTCTGAAAGTCCGCGAATGTTATGTGATACAGCACTGGAAAGCTGAGATTCTCTTCTTTATGCCAATCTTTGAATTGTATGAATCGGATCAGCGGATCAAAAGTTATTAAACATTTAAGAGCAATACTTATTTTTAGCCGCGGGCGGCTGTCTCGGTCTTTAAGGGTTAATAATAAATCTAAGCTCTTAATTCTTTTTTTTTGCTAAAATGTGTTTATATATAAATATGGCATGTGATTTATCCGTCTATAGGTGGACCTCTA[T/A]GTGTGTTTAGTGTGTGGAAAGGGAAACGACGAGGATCGGTTGTTGCTATGCGACGGTTGTGATGACAGCTACCACACATTCTGCTTAATCCCGCCCCTAACCGATGTTCCGAAAGGTGATTGGCGGTGCCCTAAATGTCTGACTCAGGTAGGTTTGATTAGTAAACAATAAATCTGTTGGTTCATCATCATTTAAAGTAAATAGAGCAGCAGGACATAAATTTGACAGCACCGCATAAAGCATCCCTAACCAAACAATGCAGCTTTTGTAGAGACTATAAGTGGGATCAAAGATTGACTCATTATTTTTGTGTTTCTGCAGGAGTGCTGTAAACCTCAGGAGGCATTTGGCTTCGAGCAAGCACACAGAGACTATACTCTCAAAGCCTTTGGGGAAATGGCAGACTCCTTCAAGTCAGATTATTTCAACATGCCTGTTCATGTATGTAAAAATCCCTACTGAAGCTGTTGAGTCTCTTGATTATATATTTACAAATCTAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41230
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005583 Nonsense 344 1522 9 28
ENSDART00000108508 Nonsense 325 1503 8 27
Genomic Location (Zv9):
Chromosome 8 (position 29183610)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 28311528
GRCz11 8 28330667
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCGGTTGTTGCTATGCGACGGTTGTGATGACAGCTACCACACATTCTGCT[T/A]AATCCCGCCCCTAACCGATGTTCCGAAAGGTGATTGGCGGTGCCCTAAAT
Long Flanking Sequence:
TGATATAGCGAGTTTGAACCAATCTGGGCATGGAGGAGGGACAATGCATCAATATATCATGTCTGGTTTGTCCGGAGACACAGTGACGAGCGTTTCTTTGTCAAATCAGCGTTGTCAAATTTTGATGACGTAACCGCACTGATTTCGGAGCCTCTGAAAGTCCGCGAATGTTATGTGATACAGCACTGGAAAGCTGAGATTCTCTTCTTTATGCCAATCTTTGAATTGTATGAATCGGATCAGCGGATCAAAAGTTATTAAACATTTAAGAGCAATACTTATTTTTAGCCGCGGGCGGCTGTCTCGGTCTTTAAGGGTTAATAATAAATCTAAGCTCTTAATTCTTTTTTTTTGCTAAAATGTGTTTATATATAAATATGGCATGTGATTTATCCGTCTATAGGTGGACCTCTATGTGTGTTTAGTGTGTGGAAAGGGAAACGACGAGGATCGGTTGTTGCTATGCGACGGTTGTGATGACAGCTACCACACATTCTGCT[T/A]AATCCCGCCCCTAACCGATGTTCCGAAAGGTGATTGGCGGTGCCCTAAATGTCTGACTCAGGTAGGTTTGATTAGTAAACAATAAATCTGTTGGTTCATCATCATTTAAAGTAAATAGAGCAGCAGGACATAAATTTGACAGCACCGCATAAAGCATCCCTAACCAAACAATGCAGCTTTTGTAGAGACTATAAGTGGGATCAAAGATTGACTCATTATTTTTGTGTTTCTGCAGGAGTGCTGTAAACCTCAGGAGGCATTTGGCTTCGAGCAAGCACACAGAGACTATACTCTCAAAGCCTTTGGGGAAATGGCAGACTCCTTCAAGTCAGATTATTTCAACATGCCTGTTCATGTATGTAAAAATCCCTACTGAAGCTGTTGAGTCTCTTGATTATATATTTACAAATCTAACCTTAAATCATGTCACTTATCATTAAGAAGCTCTGTTTTTTTTTTCTTGTGAACGATATTTGATGTAGATGGTACCCACTGAATTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa11572
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005583 Nonsense 382 1522 10 28
ENSDART00000108508 Nonsense 363 1503 9 27
Genomic Location (Zv9):
Chromosome 8 (position 29183321)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 28311239
GRCz11 8 28330378
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGCTGTAAACCTCAGGAGGCATTTGGCTTCGAGCAAGCACACAGAGACTA[T/A]ACTCTYAAAGCCTTTGGGGAAATGGCAGACTCCTTCAAGTCAGATTATTT
Long Flanking Sequence:
CGCGGGCGGCTGTCTCGGTCTTTAAGGGTTAATAATAAATCTAAGCTCTTAATTCTTTTTTTTTGCTAAAATGTGTTTATATATAAATATGGCATGTGATTTATCCGTCTATAGGTGGACCTCTATGTGTGTTTAGTGTGTGGAAAGGGAAACGACGAGGATCGGTTGTTGCTATGCGACGGTTGTGATGACAGCTACCACACATTCTGCTTAATCCCGCCCCTAACCGATGTTCCGAAAGGTGATTGGCGGTGCCCTAAATGTCTGACTCAGGTAGGTTTGATTAGTAAACAATAAATCTGTTGGTTCATCATCATTTAAAGTAAATAGAGCAGCAGGACATAAATTTGACAGCACCGCATAAAGCATCCCTAACCAAACAATGCAGCTTTTGTAGAGACTATAAGTGGGATCAAAGATTGACTCATTATTTTTGTGTTTCTGCAGGAGTGCTGTAAACCTCAGGAGGCATTTGGCTTCGAGCAAGCACACAGAGACTA[T/A]ACTCTCAAAGCCTTTGGGGAAATGGCAGACTCCTTCAAGTCAGATTATTTCAACATGCCTGTTCATGTATGTAAAAATCCCTACTGAAGCTGTTGAGTCTCTTGATTATATATTTACAAATCTAACCTTAAATCATGTCACTTATCATTAAGAAGCTCTGTTTTTTTTTTCTTGTGAACGATATTTGATGTAGATGGTACCCACTGAATTAGTGGAAAAAGAGTTCTGGAGGTTGGTCGGCACCATTCAGGAGGATGTGACAGTGGAATATGGCGCTGACATTGCCTCAAAAGAGTTCGGAAGTGGGTTTCCAATCAAAGGTGGAAGATTTAAGATTGCACCGCACGATGAGGTATAGCTGCTGCATCAATTCTGGCATATTACTCATAACGTAACTTATTAATTCCATTTCTATACCAAGTACATCCTGTTTCCATTGCTGATGTTGCTGTTTTGTGAATTCACTTGCTGTAGAAATATCTTCAGTGTGGTTGGAACCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14544
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005583 Nonsense 661 1522 15 28
ENSDART00000108508 Nonsense 642 1503 14 27
Genomic Location (Zv9):
Chromosome 8 (position 29180518)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 28308436
GRCz11 8 28327575
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGGCTGACTGTCTTGATGTGGTTCTGGCGTCAGCCGTACAGAAGGACATG[C/T]AGCTCATGATCAAAGAAGAGAGAGAGCTGCGGGAGAAAGTCCGWAAGATG
Long Flanking Sequence:
TCACAATCATGAATCCTAATACACTCATGGCCCATGGAGTACCAGTGAGTAGCATATTAATACACAAACATTTATACACACAATCATTTACCCCACCTGTGAGTAACAAGCATGAATCTCTTTTTAGATTTACAGAACCAATCAGTGCGCAGGAGAGTTTGTCATTACTTTTCCGCGATCCTATCACAGTGGCTTCAACCAGGGCTTCAACTTTGCAGAGGCTGTGAACTTTTGCACAGTGGACTGGGTGAGATTTTCCTGGATCCATCCTGGCATTACACTGTTACCTACATTTTCTTGGGCTGATGTGATTATAATAATTTTGCTTCATTTTTTTTCTCTTAATATGTGTGCAGATGCCACTGGGGCGTCAGTGTGTGGATCACTACCGCCAGCTGCATCGCTACTGTGTGTTTTCTCATGATGAGATGGTGTGTAATATGGCCATGAAGGCTGACTGTCTTGATGTGGTTCTGGCGTCAGCCGTACAGAAGGACATG[C/T]AGCTCATGATCAAAGAAGAGAGAGAGCTGCGGGAGAAAGTCCGTAAGATGGTGAGCGAACACAATTTAATCCTGTCAAGTCAATGCAGTTTGGGTGGATGACACTTCATGGCGCAGTGCTTATTATCCTTCTCGCTTTGGGAAATAGTGATGGGAGGTTTGGATCATTTTATTCACTCCATTGAGTCCATTGGGTTCTTGTTTATTTTTCAAGTCAATGTGCCAAAATATTATTCATATGTTATGAGTTTCTTCCAAACCAAACATTTACAACTAGCCCAAACCTTCACTACAAACAAGTCATGACTAGAATGCTATGAGAAAGAGAAAATAATCATTTGTTTATACATTTACCTGGATCTTTTGTCTATGATTAGCACACCAATGCACAGTCTGAGCTGGAAGGACCAATGATTAGTTCACCTCTTGAAGTCTTTGGGTTTTTGAGTCGTTTGTTTGTCATGTGACAGCCTGACCGGTGCATTTCCACTACAGCATCCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21313
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005583 Nonsense 1361 1522 26 28
ENSDART00000108508 Nonsense 1342 1503 25 27
Genomic Location (Zv9):
Chromosome 8 (position 29166195)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 28294113
GRCz11 8 28313252
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGGTCTCAGTCCAGAGCTGGAGGAGCTGATGGTGGAGGGTTTGGTCCTG[C/T]AGGTTTCTTTGCCTGAGACCCAGCAGCTCTACAGGCTTCTGCTGTCTGGC
Long Flanking Sequence:
AAAAAGTGCTTAGGTACCTTAAATAATGTTTCTGTGCTCTTTGGTCAAGGGAAAATCTTTTTTTCCACATTTTTTTGAGTGCCTTGAACTGATTTTTGCTGTTTATTCTTTTATAGGTATATTGTAACTTATATTTGTAATCTGGTTTATATAAAATATATTTAATATTTAATGGTTAAGTTGTTTAATTATCTACTAATATTAAACTAGTTTTTATTTTTTTATATTAACTATAAATAATTAACTTGTTGACTTTTGTTGTAGCTGCAGCTGTGTGGCTCTCCATCTCGGTGTCAGGACTGGGCAGTTTCAGGGCAGGAGCAGACGGTGTTTTACACAGAACAGCGCTGTATTCCTCTCCAGGGTCTGTATCTTGTTCACATCTGCTGAAATCTTGTTGTGCGTAATATTAAAACCGCAGCTGTTTTATGCTGAATCTCTGTGTGTGTTCAGGTCTCAGTCCAGAGCTGGAGGAGCTGATGGTGGAGGGTTTGGTCCTG[C/T]AGGTTTCTTTGCCTGAGACCCAGCAGCTCTACAGGCTTCTGCTGTCTGGCCCGCCAACCACAAACACGTCCCACGCAGAACACAAGTCCTACCTCACACCACCACAGACAGAGGTAAACACTGAGAGCCTCGAAACAGATTAGATATTTACATTAAACTTAAAACACTGAGAAGAACAATCAAAAAATTCCCTCCAATAGTGATAATGTTTAAATAATTCAGCACAAACAGACCAAGAGTTCTGAGTTGAGCAAAAGTGTATAGGAATATTAGGCTTAGTGTTGGATATCTGGATTTCAGATGAAGGAGAGCCGCCTTGAATCCACCAATCAAGGGAGGCTGCTGTTACCATGGCAACCAGAACCATGGCAAAATAGCTCAGCAACAGCTTTCAGATCTCATAAAGCATGGGTTACATAATTTAACCAGTTTGCCTGCTATCTGGTTAGATTTGAATCATTTTCAACAAATATGGTCATACTGAGTAGTTCTATTATTTT
Associated Phenotype:
Not determined