Busch Lab

ZMP

atp1a1

Ensembl ID:
ENSDARG00000002791
ZFIN ID:
ZDB-GENE-001212-1
Description:
Na+/K+ -ATPase alpha 1 subunit [Source:RefSeq peptide;Acc:NP_571761]
Human Orthologue:
ATP1A1
Human Description:
ATPase, Na+/K+ transporting, alpha 1 polypeptide [Source:HGNC Symbol;Acc:799]
Mouse Orthologue:
Atp1a1
Mouse Description:
ATPase, Na+/K+ transporting, alpha 1 polypeptide Gene [Source:MGI Symbol;Acc:MGI:88105]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa31185 Essential Splice Site Available for shipment Available now
sa13646 Nonsense Available for shipment Available now
sa19398 Essential Splice Site Available for shipment Available now
sa15598 Nonsense Available for shipment Available now
sa12184 Essential Splice Site Available for shipment Available now
sa38236 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa31185
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081047 Essential Splice Site 4 1028 1 22

The following transcripts of ENSDARG00000002791 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 1469144)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 1564564
GRCz11 1 1712358
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AATTCCCAGGTGGTCGATTTTAATCAAAAGCAGCAAAATGGGACGAGGAG[T/C]AAGTGTAAACCCAATTGTTGATTCACTTTTTATATCGGTTTGTCCAGTTC
Long Flanking Sequence:
GGCTTAACCTGGATATTCCAACAGGGTCTTAATGTTGAATGTACAGTCTAAAGGTCTCATTTCACAGATTAAAATCAAAGACGCCGGCTTCTGCTCTCTGATAGAGGAAAGCCACTGGTGGGCATTTTTCTCCAGCGTGATCAAAGTTCAGAGGTGAAAGTCTGTACTGTTCTGTTCTCCCGCGGCTCTTCTTCCCCGTAGACCCCGCCTCTTTTCCTCCGCGTTACCATGACGATCCGTGCATACGTCATACTGAAAAACCGCACTATATATAAGCTTTGAATGAACTGACTGTAACGCGGCTCGGATGCGTGTCTGGGTGGTACTACGCGTCCGGCGGTGACCAAGGAGAGAATACATTTGAAAAAGCCCCAAAAAGAGAGGAAACGGGATCGGGGACTTTTAATTTGTTGTTTTGAAAGAAAGCTCGGATTTGTTTTATTTTTTGGGAATTCCCAGGTGGTCGATTTTAATCAAAAGCAGCAAAATGGGACGAGGAG[T/C]AAGTGTAAACCCAATTGTTGATTCACTTTTTATATCGGTTTGTCCAGTTCTGTGTTTGAACGCAGTGTTTTTAAAGTAACCACAAGATGATCAACTGGTAAACGGCTTCTCGCCGTTCTAGACTTCCGCAGTTTTCATATTCAAATGAGTTTTAAATGAATGAAATGTGCGCAGATGTTCATCTAAACTACTTGTGAAGTCTGTTTTCGATAGTGGAGCAACAGGTTTTCCAGTCTGTGGCTTTAAAAGGGAGTCAAACTCCATTTTAAGACGTTCCTCGATCACTAGAAAGATTTGAGGAATGTAGCAGACACTAAACTTCCTCTATGGCCGCGGTGTTACACGGCCTGTTTGTCTAAGCAGATATAGTTGAAATCTCGTGACTTTTACACTGTAAAACTGAAGTAATCATGTGTGTCGCAATTGAGCTGCTAAGCAGTTCTTATGAGGGGGAAAACAAACTTAAAGCTCTTTATCTATTGCTACAGAACATAACTAGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13646
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081047 Nonsense 114 1028 4 22

The following transcripts of ENSDARG00000002791 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 1474627)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 1570047
GRCz11 1 1717841
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CAGCTCTTTGGAGGATTCWCAACTCTCCTGTGGATTGGAGCCATCCTTTG[T/A]TTTCTTGCCTACGGCATCCTGGCGGCCTCTGAGGAGGARCCTGCCAATRA
Long Flanking Sequence:
AGGAAGGCCGAGAACAATATGAGCTGGCAGCCACCTCAGAGCAGGGGGGCAAGAAGTCAAAGTCCAAGGGCAAGAAAGAGAAGGATAAAGACATGGATGAACTCAAAAAAGAAGTGGACTTGGTGAGTTAGTTTATGAGCATAAATCCTATAATGGCTATCGTAACTTTTGATAGGATGGTAAAATGCTGTTTTTATTACATCTTTGTAGGACGATCACAAACTGTCCCTGGATGAGCTCACCAGGAAATATAACACTGATTTGACAAGGGTAAGACTGTATTGGATGAACAGCTTTGGAAATGTAAGTCTCAGTTTGGATCTTCATTATCTAACCCATCACTTTATCTAGGGATTGTCAGGCACTCGTGCTAAGGAGATCTTGGCACGTGATGGACCCAACGCTTTGACTCCACCTCCCACAACCCCAGAATGGGTCAAGTTCTGCAAGCAGCTCTTTGGAGGATTCTCAACTCTCCTGTGGATTGGAGCCATCCTTTG[T/A]TTTCTTGCCTACGGCATCCTGGCGGCCTCTGAGGAGGAGCCTGCCAATGATAATGTAAGGAGAAAACCCTGTTTGTGTGTCTTAAGGATTTGCCTTCTTAAGATCATGTTGTTTTAGCACCAATCCTAACATCTCCTTCATTGTCTTGCACAGTTGTATCTGGGTATTGTGCTTTCTGCTGTCGTGATGATCACTGGATGCTTCTCGTACTATCAAGAAGCCAAGAGCTCCAAGATCATGGACTCTTTCAAGAATTTGGTTCCCCAGGTACTTATTGATATTATATTGCATAGATTGTTTTATAAGTGTTATATTTTCCTGACTCTGACGAATGTGAATTCCCACTTTGTCTTATAGCAAGCCTTGGTTATCCGTGATGGTGAGAAGAAGAACATCAACGCTGAAGAAGTTGCTGTCGGAGATCTTGTGGAAGTCAAAGGTGGTGACAGAATTCCTGCTGATTTGCGTATCATTTCTGCTCATGGATGCAAGGTAAAGTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19398
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081047 Essential Splice Site 344 1028 8 22

The following transcripts of ENSDARG00000002791 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 1475668)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 1571088
GRCz11 1 1718882
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGGTATCATTGTTGCGAATGTACCAGAGGGTCTCTTGGCTACTGTAACT[G/A]TAAGTGTCAGAGGAATTGCTACAGATTTAGTTAAATTTAGTTCTACACGT
Long Flanking Sequence:
CAAGCATTTACAAATAATTGTTGTCTTCCTAGGTGGACAACTCCTCCCTCACTGGAGAATCTGAACCCCAGACTCGTACTCCTGACTTTTCCAATGATAACCCACTGGAGACCAGGAACATTGCGTTCTTCTCTACCAACTGTGTTGAAGGTACAAAAAGAGGTCTTTTGGGGATTAAGCATGGTGTTAATCAACAGTAGATGTTTTCATTGCCTTATGCTTTACATCTAGGTACTGCCAGAGGAATTGTCATCAACACTGGTGACCGCACAGTCATGGGTCGCATCGCCACTCTCGCTTCTGGCCTTGAAGTTGGTCGCACCCCCATCTCTATTGAGATCGAGCACTTCATCCACATCATCACTGGTGTAGCTGTCTTCCTGGGTGTGTCCTTCTTCATCCTCTCCCTCATCCTTGGGTACAGTTGGTTGGAGGCTGTCATCTTCCTGATTGGTATCATTGTTGCGAATGTACCAGAGGGTCTCTTGGCTACTGTAACT[G/A]TAAGTGTCAGAGGAATTGCTACAGATTTAGTTAAATTTAGTTCTACACGTAGACAAACCTCATTCTTGTCGTGTTCAGGTGTGTTTGACTCTCACCGCCAAACGAATGGCAAAGAAGAACTGCCTGGTGAAGAATCTTGAAGCTGTGGAGACTCTTGGCTCGACCTCCACCATCTGCTCTGACAAGACTGGAACTTTGACCCAGAACCGGATGACCGTCGCTCACATGTGGTTCGACAACCAGATTCATGAAGCAGACACCACAGAGAACCAGAGTGGAACGTCTTTTGACAGGAGCTCTGCTACTTGGGCCGCCCTCGCTCGTGTTGCTGGCCTCTGCAACCGCGCCGTCTTCCTTGCTGAGCAAGAAAACATCCCAATTCTTAAGGTCTGTGTTTATGCGTTGTCTGTCAAAAGATTTACCGGTCCTTGCAGTGTATGGAGAAGTAGTTTTTCATCTTGCGCCCTGTTCACACAAATACGTGTATTTTCAAAACCACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15598
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081047 Nonsense 569 1028 12 22

The following transcripts of ENSDARG00000002791 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 1478569)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 1573989
GRCz11 1 1721783
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
MAACRTGTTGTTTCTCCACAGGATTCTGCCACTTCAATCTTCCCGATGAA[C/T]AGTTTCCTGAGGACTTCCAGTTCGATACTGAAGAAGTGAACTTCCCCACT
Long Flanking Sequence:
TTTCAGAGATCCCATTCAACTCCACCAACAAATACCAGGTATAACTGTCTTTGGCTTAGGATGTCACTTTAAAATTTACCAGTGTACACAGAATGAAACGTCATTGCATTGGCTAGGCAGTTTTAAAAATAACAATAGCGACTTTGACTTTGGATGAATATCAGATTTCTAATAGCTTCTTTTTGTGAATCTCCTTTTTTAGCTCTCCATCCACCAGAACCCCAACAGCAATAACACTGAAAGCAAACACCTGCTAGTAATGAAAGGCGCTCCTGAGAGGATCCTGGACCGGTGCTCCTCTATTTTAATCCAAGGAAAAGAGCAGCCTTTGGATGATGAGATGAAGGATGCTTTCCAGAATGCCTACCTGGAACTTGGTGGTCTTGGAGAGAGAGTACTGGGTGAGTACTGGCATTGCTATACTACGCATTTCCATGCGACGCGTTCCTTCAACGTGTTGTTTCTCCACAGGATTCTGCCACTTCAATCTTCCCGATGAA[C/T]AGTTTCCTGAGGACTTCCAGTTCGATACTGAAGAAGTGAACTTCCCCACTGAGAACCTGTGCTTTATTGGCCTCATGTCCATGATTGATCCTCCTCGTGCCGCTGTACCAGATGCTGTGGGCAAATGCAGGAGCGCTGGAATCAAGGTATGATTTAAAAACTGCTCATCTTAAAGAAACAGAAATGCATTGGCTACAAATTAAAAATCTCTTTTCTAGGTTATCATGGTTACCGGTGACCATCCAATCACAGCCAAGGCCATTGCCAAGGGGGTGGGTATCATCTCAGAGGGCAATGAAACTGTTGAAGACATCGCTGCTCGCTTGAACATCCCTATTAATGAGGTCAACCCAAGGTAATTGGTTCCTCTTCTTCAATTCGAATGTTTTCTTGCTGGATATTTATAGTGTCTAGCTTTTAATTCCATTTAATGTGCAACATGTAATCACTGTCAAGCCTCTCTCATCTTAAAAAATGTGAAATTTTAAAGATTACTAGAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12184
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081047 Essential Splice Site 821 1028 16 22

The following transcripts of ENSDARG00000002791 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 1480295)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 1575715
GRCz11 1 1723509
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TACCTTTGGGCACCGTCACCATTCKCTGTATTGATCTGGGTACCGACATG[G/T]TRAGCACTGCATTTRATTGGTTCTATTTAATAGYTGGTTGGTGAGGTTAA
Long Flanking Sequence:
AATTAATGCTCTGAAATACAACTAAGACAAGTTTGGTTTGGACAAGACTTTGGACGTGTCACAACACTGGCTTACATTCATTTGCGTTTATCCACAGGGTGCCATTGTAGCCGTAACCGGTGATGGTGTCAATGATTCTCCAGCTCTGAAGAAGGCTGACATTGGTGTGGCTATGGGTATTGCTGGATCTGACGTATCCAAACAGGCTGCTGACATGATCCTTCTGGACGACAACTTTGCCTCAATTGTCACTGGAGTAGAAGAAGGTATGTCATATTTTGGGAACTTGCTTTGACTGAATAATTCTGAAGAGTCAAATCTCAAACATATCTTCCATATGTTTAGGTCGTCTGATCTTCGACAACTTAAAGAAGTCCATTGCCTACACACTGACCAGTAACATCCCCGAGATCACCCCTTTCCTTCTGTTCATCATTGCTAATATTCCTCTACCTTTGGGCACCGTCACCATTCTCTGTATTGATCTGGGTACCGACATG[G/T]TAAGCACTGCATTTGATTGGTTCTATTTAATAGCTGGTTGGTGAGGTTAATAAATGATATTGTCCTGTTATCGTCAAGGTTCCTGCCATCTCATTGGCCTATGAAGCTGCCGAGAGTGACATCATGAAGCGTCAACCCAGAAACCCCAAAACAGACAAACTTGTGAATGAGAGGCTCATTAGCATAGCCTACGGTCAGATCGGTAAGCATCTCAGATGCTCTATTAAAGGCATGGTTCACCCAAAAACTCGTCGTTTACTCAACCTTCTCTGGTCACTATTTGACTTTCTTTCTGCTGTTGAACACCGAAGAAGATATTGTAAAGAAATCTGGAACCATTTAACCATTGACTTCCATAGTAGGATTAACAAATACTATTGAAGTCAATGGTTGGTTTCTCTTCTTTCTTCAAAATACCATATTTAAAAGGTTCCCAATTGAAGTTGGGTAAATCTTTCATTTTTGGGTGGACTTGATCTGTTGGTGTTCACCAGGTGTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa38236
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081047 Essential Splice Site 955 1028 19 22

The following transcripts of ENSDARG00000002791 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 1481207)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 1576627
GRCz11 1 1724421
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGATCATCTGCAAGACCAGAAGAAACTCTGTCTTCCAGCAGGGAATGAA[G/A]TAAGTGGATGGGTAATAATTCAGTATGTTTCTGAGCGTCTTGTATCAGAG
Long Flanking Sequence:
AAATACCATATTTAAAAGGTTCCCAATTGAAGTTGGGTAAATCTTTCATTTTTGGGTGGACTTGATCTGTTGGTGTTCACCAGGTGTGTACTGTAGACTTTGAGGATTGAATCCCAATGCTTCTGCTTTCCCCACAGGTATGATTCAAGCTCTGGCTGGGTTCTTCACATATTTTGTCATCTTGGCTGAAAATGGCTTCCTACCATCATCACTGCTGGGCATTCGAGTGTTTTGGGATGACAAATACGTCAACGATCTGGAGGACAGTTATGGCCAGCAATGGGTGAGTGTTGTCAATCATCCAATAAGCAGATGACATCTCTGCTTGTCCAGCATCTAATCTGAATATTGTGTTCCTGGCCATCCCAGACGTACGAGCAGAGGAAGATTGTGGAGTTCACATGCCACACTGCCTTCTTCACCAGTATAGTGATTGTACAGTGGGCAGATTTGATCATCTGCAAGACCAGAAGAAACTCTGTCTTCCAGCAGGGAATGAA[G/A]TAAGTGGATGGGTAATAATTCAGTATGTTTCTGAGCGTCTTGTATCAGAGGTCTTACGTGTTTGCTGTTGTCTTGCAGAAATAAGATTCTAATCTTTGGATTGTTCGAAGAAACCGCTCTTGCAGCTTTCCTGTCCTACTGCCCGGGCATGGACGTAGCCCTCAGAATGTACCCACTTAAGTAAGTCAAGCCTCTTTACCAGTATTTGTTAATCATCTAGACATGTTTTGTTATGACGTTTGGGAATGTTTTTTAACATAAACTGCAAAAAATCCTTTTCTATCTTTGAGTTTTGTCTGGTTTCTTGTCCAAATATCCCAAAAAAAAAATCCTAATTCTCTTTCGGATAAGATGTTAAAGGGCCAGGAAATCCCCTCGTTTCAGCAGGGTGTTTTCACACCTCTACTTTGGAAAAAGTCAGAAAAGTGGGCGTGTCCAGCTCTGTTTAGGGGGGAGTGTCGAAGGAAGAAAAGTGGGAGGGTGTGGGAGTGTCTATTTGG
Associated Phenotype:
Not determined