Busch Lab

ZMP

pdx1

Ensembl ID:
ENSDARG00000002779
ZFIN ID:
ZDB-GENE-990415-122
Description:
pancreas/duodenum homeobox protein 1 [Source:RefSeq peptide;Acc:NP_571518]
Human Orthologue:
PDX1
Human Description:
pancreatic and duodenal homeobox 1 [Source:HGNC Symbol;Acc:6107]
Mouse Orthologue:
Pdx1
Mouse Description:
pancreatic and duodenal homeobox 1 Gene [Source:MGI Symbol;Acc:MGI:102851]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa3263 Nonsense F2 line generated Not yet available
sa280 Nonsense Confirmed mutation in F2 line Not yet available
sa37883 Nonsense Mutation detected in F1 DNA Not yet available
sa12 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa3263
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000014696 Nonsense 37 246 1 2
ENSDART00000014696 Nonsense 37 246 1 2
Genomic Location (Zv9):
Chromosome 24 (position 22292343)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 21539221
GRCz11 24 21684395
KASP Assay ID:
554-2912.1 (used for ordering genotyping assays)
KASP Sequence:
CAGAGACACCCCAACGAAGACTACAGCCAAAACCCTCCACCGTGTCTTTA[T/A]ATGAGACAGGCACATTCAGTATACGCCTCACCATTGGGCGCACAGGACCA
Long Flanking Sequence:
GTGACAGCGTTTCCCCCGGAGAGTCAAGAGACTATTCCGATTCACCTGTCTTTGCAGTACCCAAGAACTGCAGGTGTAGCACATACAGTCGCAGGTAAACAGAACATGTTTGCCAAGGGCATTGATTTGAGCGTGGTCAGTTCTGTTCAATTATTGTCAAAGCGCGGAGCAGTCGAAAGGAAACATGAACAGAATCTACTGCCAGTTGACAGCTTTGTGTAAACAGTGAAACCAATGGTGCGGCAGGGTCACATGGTCACGATGGCACACCTATGAGGCCCCGAGCGGCGCCAGACGCTCAGACTGCAGGTAGAGCAGAGGTCCTGATCAGGGGCAGGGCGCTGGCTCATGTGCTCGTGTACGGCACGGTTTCCCCGGTCTATGGCAATCATGAATCGGGAAGAGCATTACTATCCGCCTAACCACCTGTACAAGGACTCTTGTGCCTTCCAGAGACACCCCAACGAAGACTACAGCCAAAACCCTCCACCGTGTCTTTA[T/A]ATGAGACAGGCACATTCAGTATACGCCTCACCATTGGGCGCACAGGACCAGCCAAATCTTACCGACATTACTTCTTATAACATGTCGAGCCGGTATGATCTGGCAGGGCCTCATCTTCACCTTCCCCAAACTTCACAGACATCTCTACAGTCGCTCGGGGGTTACGGAGACTCTCTGGACCTCTGCGGGGATCGGAACAGATACCATCTCCCATTTCCGTGGATGAAGTCAACCAAATCTCACACGCACGCATGGAAAGGACAGTGGACAGGTAACTCGTACTTTGGCCATTAATCTTTGTTCACCAAATAACTCCTGATTGCAGGCCATCAAGTCAAATTCATGCCTATGATGTTCCAAATCAATCTAAACATTTGTTCCGTTTCAAGAGGTACAGGTTAGTTGATTAAAGTTAAAAATGCCAGTCCACTGATGCTTAGTAAAAACTAAATCTTTGACTACCTGTTGTATTGCCTGTTGTATATGAACAGTTGTGTTGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa280
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000014696 Nonsense 37 246 1 2
ENSDART00000014696 Nonsense 37 246 1 2
Genomic Location (Zv9):
Chromosome 24 (position 22292343)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 21539221
GRCz11 24 21684395
KASP Assay ID:
554-2912.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGAGACACCCCAACGAAGACTACAGCCAAAACCCTCCACCGTGTCTTTA[T/A]ATGAGACAGGCACATTCAGTATACGCCTCACCATTGGGCGCACAGGACCA
Long Flanking Sequence:
GTGACAGCGTTTCCCCCGGAGAGTCAAGAGACTATTCCGATTCACCTGTCTTTGCAGTACCCAAGAACTGCAGGTGTAGCACATACAGTCGCAGGTAAACAGAACATGTTTGCCAAGGGCATTGATTTGAGCGTGGTCAGTTCTGTTCAATTATTGTCAAAGCGCGGAGCAGTCGAAAGGAAACATGAACAGAATCTACTGCCAGTTGACAGCTTTGTGTAAACAGTGAAACCAATGGTGCGGCAGGGTCACATGGTCACGATGGCACACCTATGAGGCCCCGAGCGGCGCCAGACGCTCAGACTGCAGGTAGAGCAGAGGTCCTGATCAGGGGCAGGGCGCTGGCTCATGTGCTCGTGTACGGCACGGTTTCCCCGGTCTATGGCAATCATGAATCGGGAAGAGCATTACTATCCGCCTAACCACCTGTACAAGGACTCTTGTGCCTTCCAGAGACACCCCAACGAAGACTACAGCCAAAACCCTCCACCGTGTCTTTA[T/A]ATGAGACAGGCACATTCAGTATACGCCTCACCATTGGGCGCACAGGACCAGCCAAATCTTACCGACATTACTTCTTATAACATGTCGAGCCGGTATGATCTGGCAGGGCCTCATCTTCACCTTCCCCAAACTTCACAGACATCTCTACAGTCGCTCGGGGGTTACGGAGACTCTCTGGACCTCTGCGGGGATCGGAACAGATACCATCTCCCATTTCCGTGGATGAAGTCAACCAAATCTCACACGCACGCATGGAAAGGACAGTGGACAGGTAACTCGTACTTTGGCCATTAATCTTTGTTCACCAAATAACTCCTGATTGCAGGCCATCAAGTCAAATTCATGCCTATGATGTTCCAAATCAATCTAAACATTTGTTCCGTTTCAAGAGGTACAGGTTAGTTGATTAAAGTTAAAAATGCCAGTCCACTGATGCTTAGTAAAAACTAAATCTTTGACTACCTGTTGTATTGCCTGTTGTATATGAACAGTTGTGTTGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37883
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000014696 Nonsense 208 246 2 2
ENSDART00000014696 Nonsense 208 246 2 2
Genomic Location (Zv9):
Chromosome 24 (position 22294255)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 21541133
GRCz11 24 21686307
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTGGAAAAAAGAGGAGGACAAGAGGAGAGCCAGGGGAGTGGATCCCGAA[C/T]AGGACTCCTCCATCACGTCCGGGGATCTTAAGGATGAATCTTGCGTCGGC
Long Flanking Sequence:
CTCAAACGCTGATTTTAAAATCAATCAGAACCTTCAATAATTTGATCAAAAGATACAAATTTCAGTTTTAAACATCTGGTTTCGGTGATAAATCTGGAATTTGCCCATAATTGGTGTAGCTCTACAAAATTAATTGAATAAGTGCTTGAGTTTAATTTTATGAAGAGATAATTTTGTGGTATCCTCAGAAATAGACTGTGTGCGATTGGGATGTCTAAAACACGACTTTACTGAAGTTTCACTCCTATAATTCTGTTTTAGGCCCTTATATGGTCGAGGCCGAGGAGAACAAGCGCACGCGCACAGCTTACACCAGAGCGCAGCTGCTCGAGCTCGAGAAAGAGTTTCTCTTCAACAAATACATCTCGCGCCCGCGCCGCGTTGAACTCGCACTCACCCTCAGCCTCACCGAGAGACACATCAAGATCTGGTTTCAGAACCGACGCATGAAGTGGAAAAAAGAGGAGGACAAGAGGAGAGCCAGGGGAGTGGATCCCGAA[C/T]AGGACTCCTCCATCACGTCCGGGGATCTTAAGGATGAATCTTGCGTCGGCACGGCAACACTTGCGGGACCCCCTTCCCCCCTGCACCCGCATGCACCTTCAGTCCAACAAGACTCTTAAACATAAGACTGTGACACGAGTTGAACTATGTATGCAACGGCAACCAGTGGCAAAAGACTGACAGCAGTTGTAAAACTCCAATATGTACAGTGCTAGCAAACAGATTGGCAAAAGGGGGCGCTCTCGATTGCCGCATTTTGGACATTGTTTGAAGGTTATGAATTTTATAGATGAAGTATGAATAAATTCTTAATTTAAAAAAAGAAATGGGTAAATACAACAACATCTCAACATTTATCATATTTATATAGTTACCACGAACATTAAAGTGATGTGAGAAGTGTGGCGTCATGTCATTTGTTTCTACATGTGCTGCTGGTCAAAAATGGCTAGAGTTTGTATTTGAATAAAATTAACATTTTAGTCCACACGTTTTTTTAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000014696 Nonsense 208 246 2 2
ENSDART00000014696 Nonsense 208 246 2 2
Genomic Location (Zv9):
Chromosome 24 (position 22294255)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 21541133
GRCz11 24 21686307
KASP Assay ID:
1198-0001.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTGGAAAAAAGAGGAGGACAAGAGGAGAGCCAGGGGAGTGGATCCCGAA[C/T]AGGACTCCTCCATCACGTCCGGGGATCTTAAGGATGAATCTTGCGTCGGC
Long Flanking Sequence:
CTCAAACGCTGATTTTAAAATCAATCAGAACCTTCAATAATTTGATCAAAAGATACAAATTTCAGTTTTAAACATCTGGTTTCGGTGATAAATCTGGAATTTGCCCATAATTGGTGTAGCTCTACAAAATTAATTGAATAAGTGCTTGAGTTTAATTTTATGAAGAGATAATTTTGTGGTATCCTCAGAAATAGACTGTGTGCGATTGGGATGTCTAAAACACGACTTTACTGAAGTTTCACTCCTATAATTCTGTTTTAGGCCCTTATATGGTCGAGGCCGAGGAGAACAAGCGCACGCGCACAGCTTACACCAGAGCGCAGCTGCTCGAGCTCGAGAAAGAGTTTCTCTTCAACAAATACATCTCGCGCCCGCGCCGCGTTGAACTCGCACTCACCCTCAGCCTCACCGAGAGACACATCAAGATCTGGTTTCAGAACCGACGCATGAAGTGGAAAAAAGAGGAGGACAAGAGGAGAGCCAGGGGAGTGGATCCCGAA[C/T]AGGACTCCTCCATCACGTCCGGGGATCTTAAGGATGAATCTTGCGTCGGCACGGCAACACTTGCGGGACCCCCTTCCCCCCTGCACCCGCATGCACCTTCAGTCCAACAAGACTCTTAAACATAAGACTGTGACACGAGTTGAACTATGTATGCAACGGCAACCAGTGGCAAAAGACTGACAGCAGTTGTAAAACTCCAATATGTACAGTGCTAGCAAACAGATTGGCAAAAGGGGGCGCTCTCGATTGCCGCATTTTGGACATTGTTTGAAGGTTATGAATTTTATAGATGAAGTATGAATAAATTCTTAATTTAAAAAAAGAAATGGGTAAATACAACAACATCTCAACATTTATCATATTTATATAGTTACCACGAACATTAAAGTGATGTGAGAAGTGTGGCGTCATGTCATTTGTTTCTACATGTGCTGCTGGTCAAAAATGGCTAGAGTTTGTATTTGAATAAAATTAACATTTTAGTCCACACGTTTTTTTAT
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461