Busch Lab

ZMP

eif3eb

Ensembl ID:
ENSDARG00000002549
ZFIN ID:
ZDB-GENE-050208-283
Description:
Eukaryotic translation initiation factor 3 subunit E-B [Source:UniProtKB/Swiss-Prot;Acc:Q1LUA8]
Human Orthologue:
EIF3E
Human Description:
eukaryotic translation initiation factor 3, subunit E [Source:HGNC Symbol;Acc:3277]
Mouse Orthologue:
Eif3e
Mouse Description:
eukaryotic translation initiation factor 3, subunit E Gene [Source:MGI Symbol;Acc:MGI:99257]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa36832 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa10543 Essential Splice Site Available for shipment Available now
sa23512 Nonsense Available for shipment Available now
sa36831 Nonsense Mutation detected in F1 DNA Not yet available
sa6144 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa36832
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000023926 Essential Splice Site 30 446 None 13
ENSDART00000064209 Essential Splice Site 30 401 None 12
ENSDART00000135651 Essential Splice Site 30 401 None 15
ENSDART00000136295 Essential Splice Site 30 439 None 13
Genomic Location (Zv9):
Chromosome 19 (position 23148304)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 23079684
GRCz11 19 22664007
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGACAGGCATTTGGTCTTTCCGTTGCTGGAATTCCTTTCGGTCAAAGAGG[T/C]AATACACAGATATACAGTACAACATCGTTGTTAACTTATATAATTGATCG
Long Flanking Sequence:
ACCTTAACCCTGACCCTATGGCCAAGACTATAGGTCTAAGGGTTTAGGGATATTAACACCAATAATGATCTGCTACCAAAATTAGGTGATGACTATGTGGAACAGGATGGTAAAATAACTGTAAATAGATTAGTCCTGTGTAATACAGAAAAAAAGAAAATAAAAAAATAGGAGAACCTTTAAATAGTTTGAAGTAGATCCTATTTGTTTGATACCCCCTCCCTCTATATCTATTTATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGTGCGTGCGTGTGTGGGACAGAAGCAGCTCACTGTTCTCATCAGTGCTGAAATAAAGTTTTTTAAACGCTCTTCTTATTTTCAAAATGGCGGAGTACGATCTGACTACCAGAATCGCTCATTTTTTAGACAGGCATTTGGTCTTTCCGTTGCTGGAATTCCTTTCGGTCAAAGAGG[T/C]AATACACAGATATACAGTACAACATCGTTGTTAACTTATATAATTGATCGGTAATCGCAGAACTGCACATCGCACGTGTGGTGAATACCGTTAGTTATCTGATCGAGATAAATAATTTCTTATCCCATAATAAAACAATGATGACATCTTTGGACCATTGTGTTAAACGTTTTATTTATTGCTGTTTTTGACAGATCCGTTTTTATTCAAAGCATAAGAGCCTTTGCTAGCACAAATCCTGTGTTTCCAGGGACATCACCATGTTTTTGTGTTATAACAGTGGTGTAACTTTGTATGTAGCGTATATAAAACTAATAAATTAATATAACGTTATTTAATAACACTGGTTTTATATTCGCAAAATCTGACTTCCATTTCAGAAACGTATTATTTGCAAATTCTAAACGGTAAAATCATATTCTCAATTACTATCAAAGTACTGCATTGTTTACAATCAATTACATAGTGCTAATGTTGTTTTGAAGTCATACTTGCATGTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10543
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000023926 Essential Splice Site 158 446 5 13
ENSDART00000064209 Essential Splice Site 158 401 5 12
ENSDART00000135651 Essential Splice Site 158 401 5 15
ENSDART00000136295 Essential Splice Site 158 439 5 13
Genomic Location (Zv9):
Chromosome 19 (position 23142181)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 23073561
GRCz11 19 22657884
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGGAAACTACTCTGGAGCTGCAGAGTATCYCTACTTTTTCCGCGTGCTTG[T/A]AAGCAAGASCACTAATGTTTCATTTAGTTTTTGTTTGTTTGYTTAATTTG
Long Flanking Sequence:
AACGGAACCCATAGTGAAGATGTTTGAAGATCCAGAGACTCAGAGACAGATGCAGTCCACCAGGTCTACTGCCAACATAATACTGTTTATTGCTCTGTAAAATATAATATATTAGACTGTGGAGTTGCCTTAATGTAACTCTACTACTATGTCACTACTATAAAGTTCTTGTGTTTTTTCTTAGAGATGGAAGGATGCTGTTTGAATATTTAGCAGACAAACATAGTGTAAGTGTTTCAACACATCTCAAATATTTTTATTTTTTTAATATATTTTATATTAAAATAATTTATTATTTTATTTTATTTTATTTTAATTATTATATTTTGTATTTTAGAGTAGCTAATTGACCACTTGTTTAATTTTTTATTGATTTTGATTTCTCTTCCCTCAGTTTCGTCAGGAATATTTGGATACACTTTACCGCTATGCCAAGTTCCAGTATGAGTGTGGAAACTACTCTGGAGCTGCAGAGTATCTCTACTTTTTCCGCGTGCTTG[T/A]AAGCAAGACCACTAATGTTTCATTTAGTTTTTGTTTGTTTGTTTAATTTGATTTGTGAAGTGTGAAATAGACTTTAAAATTACAGCCTTAAGGGAGAGGGTTAGAATACATTAATTTGTTTCATCCCTGAGTGGTTTAACAGCTTTTATTTTTTTAGTAATTTACCTGAACAAACAATCGGCAACCATCACTTCTAGTGTTTTGAGAGGTTGTTGAACAAACAACAACAAAAAAAAGACTTTACTTTTTTCATTGTATCTTTAAAAATGTATTTAAAAAACAATTAAAAAATATATATATACTTTTATTAAACAACAACGTCAAAACTGATGTTCTAGTGTAACAAAGTTGACTTTTTTTCAAAATTATTTGCCCTCCTGTTAGATTTGAATTCTATTCTTTTACATTTCATCACTAAGTTAAAGGGAGAGGAGGTTTTTTTTCCAACTCATTTTTTTATATTTTATAGTTTCAATAACTTATTTAGAATGACTGACTTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23512
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000023926 Nonsense 171 446 6 13
ENSDART00000064209 Nonsense 171 401 6 12
ENSDART00000135651 Nonsense 171 401 6 15
ENSDART00000136295 Nonsense 171 439 6 13
Genomic Location (Zv9):
Chromosome 19 (position 23140027)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 23071407
GRCz11 19 22655730
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTCATGATCCAGGTTCCCTCCACAGACAGGAATGCTCTGAGCTCTCTGT[G/A]GGGCAAACTGGCATCGGAAATCCTCATGCAGAATTGGGAAGCAGCCATGG
Long Flanking Sequence:
TAATCATTTTAGCCTATCTAAAGGGTTAATAGTGCCAACTGATGATCAACAGTATACATTACAAATTATACCACTTCCTAACAGGAAAATCAACCATCAATCAAGAATGCATAATTATAGGGTGTCATAGCTTTGCGATCAAAAAATGTCATTATAATAGGGCAAAAACAGCTGTGAAACATAACAAAAGTGTAGTAATTTTGAACAATACACAAGGGTAAAATTAGGACAATGCTGTTCTAAAATCATTCACAAAGCACCTAATCTTGACTTAGGAATTTAAAAACTTTTTGACCCACCTCAGATGTTAACTGGAATAGGAGTTATATGTTTAACACAATTTCCTACACAAAATCGAAATGTATCAATGCTAAAGTGACAATAGCTTGCATAGATATGAGAGGGGCGAACATGATATTGGAAAATGTGTAGAAAAACTCATGGTCTGGTTTTCATGATCCAGGTTCCCTCCACAGACAGGAATGCTCTGAGCTCTCTGT[G/A]GGGCAAACTGGCATCGGAAATCCTCATGCAGAATTGGGAAGCAGCCATGGAGGACCTGACCCGCTTACGAGAGACCATCGACAACAACGTATGTCTGTCCACCATTCTTCACCATTCACCTCTGTCTAATAGAAGCTTTGATGCTGTATTCCAACAGCAAAATTTGTCTCCCTGGTTAATTTGCTTCTCCGCCAATGTTCCTTTGAGCTCCTATACAACAGACCTTTAGCAAGCATCAGGCCGTAAACACAGAACTGACCACAATGGCATTTACATTGCATCAGCTTTGACATGACATTTATTTGCGATGCAGTTAAAAAATGGATGTGTTTGGATTTACTGTGGCCCTGTTTGCTTTGGTAGTCCATGCATGGAATGTAAGATCAACTATATGACACAAGGCTGAAGCGGTGTTGACATGTTTTGAATGAAAGCATGTTTTTGTTTTGCTGCATGATTCAGTCGGTGAGTTCGCCTCTTCAGTCACTGCAGCAGAGGAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36831
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000023926 Nonsense 239 446 7 13
ENSDART00000064209 Nonsense 232 401 7 12
ENSDART00000135651 Nonsense 232 401 7 15
ENSDART00000136295 Nonsense 232 439 7 13
Genomic Location (Zv9):
Chromosome 19 (position 23139448)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 23070828
GRCz11 19 22655151
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCTTTAATCATCCCAAAGGCAGAGACAACATCATCGAGCTCTTCCTCTA[T/G]CAGCCCCAGTGAGTAGAATCAACTAAGACATACACTTGGTAAAGTATAGA
Long Flanking Sequence:
CGACAACAACGTATGTCTGTCCACCATTCTTCACCATTCACCTCTGTCTAATAGAAGCTTTGATGCTGTATTCCAACAGCAAAATTTGTCTCCCTGGTTAATTTGCTTCTCCGCCAATGTTCCTTTGAGCTCCTATACAACAGACCTTTAGCAAGCATCAGGCCGTAAACACAGAACTGACCACAATGGCATTTACATTGCATCAGCTTTGACATGACATTTATTTGCGATGCAGTTAAAAAATGGATGTGTTTGGATTTACTGTGGCCCTGTTTGCTTTGGTAGTCCATGCATGGAATGTAAGATCAACTATATGACACAAGGCTGAAGCGGTGTTGACATGTTTTGAATGAAAGCATGTTTTTGTTTTGCTGCATGATTCAGTCGGTGAGTTCGCCTCTTCAGTCACTGCAGCAGAGGACGTGGCTCATACACTGGTCACTGTTTGTCTTCTTTAATCATCCCAAAGGCAGAGACAACATCATCGAGCTCTTCCTCTA[T/G]CAGCCCCAGTGAGTAGAATCAACTAAGACATACACTTGGTAAAGTATAGAGATAAACCAAAATGAAAATTTTTGGCCGAAAAAGAGCAAACCAAGGCGAAACTGAAACACTGCAATAAATTCTGAAAATTGTTAGTACCATTGCATTCATGGCTATGACTGTGTAACAATCTAACTAAAACCAAGGCATTGTCTCAAGAATAAATCAATCACTTAGATTTTCACTTAATTATGAAAATATGTATGTAGCGCATTGCAACAATGGGTATCACTTTTGGGGATTGAGTCTTATACAGACAGATAACATCTAGCTGTTAAGTGGTTGAGTTTGTCTTCTGCTTAACATTTGAGAAAGATTAGAGAGAGTTTTTTTTTTTTTTTTTTTTTTTAATAGGACCAGTGCATAAATTATAATTTTTTATATGTAGTAGCCCCCTTCAGAAAATTTTCAGTGGCTGAATATTTGGTGCATCCCTAGTAAATTAATTTGACTAACAATTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6144
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000023926 None None 446 None 13
ENSDART00000064209 None 402 401 None 12
ENSDART00000135651 Essential Splice Site 402 401 12 15
ENSDART00000136295 None None 439 None 13
Genomic Location (Zv9):
Chromosome 19 (position 23111217)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 23042597
GRCz11 19 22626920
KASP Assay ID:
554-3677.1 (used for ordering genotyping assays)
KASP Sequence:
GTCKGTCCTGCAGCTCCCACRGTACAGCCGCAGAAATGCAGACCTCTAAT[G/T]TGGGTAGACAAGTTTGGRTACTCGTCWGGTGTGTGCCCCCACTGTGYCTT
Long Flanking Sequence:
GAATGTATAGCAATTAAAAACACCCAGCTGGATGCTACAGAGTCCAGTCAGCCTATGACAAGCGACACACAGCAGATGCGCATGCTCTCTTTTATATACACACACACACACACACACACAGAGCACCATGGAAGATGTGCGCGCTCTCACATTAACATTTAGGTGCTTTATTGGTATGACAAATAGCTGGACATTAGTATTGCCAAAGCAGTGCAGTGTAGCTGCATACAAACAAGTGCAAAAAGGGCAGTAGTGCAAAGCAGTAGTGCTCTCTCTCATTCTCCTCCCACACACACACACACACCCACAGGATACACGCGCGCGCTTTCTGTCTCTCTCTCTCTGGAGCGCTATATTGTTAGACTGCCCGCTCCCGTTCAAATTACACCAGAGTTCCTGACAGCAACGGCGTGTTGTCTGGAAATTTATTCCCGCGCAGCAAGAAAACTGGTCGGTCCTGCAGCTCCCACGGTACAGCCGCAGAAATGCAGACCTCTAAT[G/T]TGGGTAGACAAGTTTGGATACTCGTCTGGTGTGTGCCCCCACTGTGCCTTTAAAATCTCTCTTTGAATGATCATACAGGTGCAGATCATTTTGCATCATCTCTACTACACTCTTCTTCAATGTTCATATGGCTAGGAATGTTGTTCTCCTGTCTGACCACTGTGGAATAAGAAACCAATTGGGGTGAAGATATAGCACATAGAAGGCAGAGTTCCAGAACACACCCACTGACTGTATAATCACCACAGGCCAATGGTAGTGTTTAGGATCCAAAACAAAAGTTTGCTTTATTGATCTGTTTCGAGGTGTGATAACTAACTTTATAAACTTGTTTTCAGTTGGATTTTGTTCGGAAATAATGTAGCAACAGTTCATTCTTTTATTTTGTTTGAAGTATACTGGGGCTTTTATACTGTTCTCTGCTTCTCACAAATGTTTTGTGGTTAGGGTCATGTGGTGATGGGCAACAACGCAGTGTCGCCGTATCAGCAGGTGATCGA
Associated Phenotype:
Not determined