Busch Lab

ZMP

cacnb1

Ensembl ID:
ENSDARG00000002167
ZFIN ID:
ZDB-GENE-040718-399
Description:
voltage-dependent L-type calcium channel subunit beta-1 [Source:RefSeq peptide;Acc:NP_001002652]
Human Orthologue:
CACNB1
Human Description:
calcium channel, voltage-dependent, beta 1 subunit [Source:HGNC Symbol;Acc:1401]
Mouse Orthologue:
Cacnb1
Mouse Description:
calcium channel, voltage-dependent, beta 1 subunit Gene [Source:MGI Symbol;Acc:MGI:102522]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa33120 Nonsense Mutation detected in F1 DNA Not yet available
sa8705 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

This allele has been removed from public view.

Allele Name:
sa2094
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000012835 Nonsense 3 520 1 14
ENSDART00000057159 Nonsense 3 603 1 14
ENSDART00000111707 Nonsense 3 478 1 13
ENSDART00000123068 Nonsense 3 642 1 14
ENSDART00000130611 Nonsense 3 517 1 13

The following transcripts of ENSDARG00000002167 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 3 (position 15847465)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 16077684
GRCz11 3 16227484
KASP Assay ID:
554-2653.1 (used for ordering genotyping assays)
KASP Sequence:
AGGCTCCAAATGAAACAGTAAAACCGAAGTTAAAGTTTAAATCAATGGTA[C/T]AGGAGGGTAATATGTCCAGGACGCCTTCCACCTCAACCCAGGAAATCCAA
Long Flanking Sequence:
AAAAAAAAAAACGCTGAATAATCTGTTTTGTAGATGAACTCTTCATATGAAAATAAGAACTCTTCCTACGAAACGGCACAAAGGCATATTGTTGTTTTCTGTAATAAAGCAGAATCAAAGGGTGTGGTCATTTCGCTTTTATATGGAATGGGGAGTAGAGCTGCCACCGTCCATCTCATAGTAATATTGATCGATCAACCAATCAGTCCGAGAAACACAACAAAACTCCCGCCCCATTAGCAACTCATTGGTTGATGAGATGTGGAGGGCGGGGCTTGATCCCTCCGCTGAACAGCTGGAGACTGAGCTCGTTGTATTTGCTAAGGGAGAGGGTTTCAGCAGGGCTGGGGGCGCAACAGCGCGGTGACAAGCCATCTGCGAGGAGGAAAAGCACCTTCATCTGTTTAATTTTACGTTGAATTATTTCACAATGCATAACGAACTCAAATCAGGCTCCAAATGAAACAGTAAAACCGAAGTTAAAGTTTAAATCAATGGTA[C/T]AGGAGGGTAATATGTCCAGGACGCCTTCCACCTCAACCCAGGAAATCCAAATGGACATGTTCGACCACCACGGCTCTCACGCTCAGGTAAGAGAGAGAGAGGCACTTTTACAGCTTATACCGAAAGTGCATGCAACCAGTGGAAGACGAAATTTAACCCGCTTGGTCGCTGTTTTAGAAAGGCTCAGTGAAAAATCAGAGGTTTTGTTTGTGGGGAAGATTAGTCGTTATCAACCGTTGCTCGTATTGTGGTTACTTGGCAACAAGACGGCATCTTCACGCGTTTGCCACAACAGTGTTGTAAACAAGTATTCTGCAAGGAAAGCGACATAAAGTTGTGTGTGAATGACGGACAGTTGTTTTAAATGTTTCAAAACTGCATTATCTTTGGTATTAAATGGGATTTACATGATTCCATCACCGTGTCCATGTTCGCTCTCTCTCTCTCCTGACAGCTGGCCTACTACAGTGTTGCAATTTTATGACAGTCTATTCTGTTTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33120
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000012835 Nonsense 114 520 4 14
ENSDART00000057159 Nonsense 114 603 4 14
ENSDART00000111707 Nonsense 114 478 4 13
ENSDART00000123068 Nonsense 114 642 4 14
ENSDART00000130611 Nonsense 114 517 4 13

The following transcripts of ENSDARG00000002167 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 3 (position 15811735)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 16041954
GRCz11 3 16191754
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTCTGAAGACCAAGCCTGTAGCGTTTGCAGTGAGGACTAACGTTGGCTA[T/A]AACCCAGGCCCTAATGATGATGTGCCTGTTCAGGGCATGGCCATCTCTTT
Long Flanking Sequence:
AAATATTTTTTAACATGTATTTACCACAGCTGTATTATATAAATGACCATGCATGGTTCTTTATCAGATAAAGGGTTTAAAATTGTCGTTTTGTGATACATTTTCATCCTATTCACCACACACTTGGTTGAATGATTGTATTGTAATATATAGTGTTAATTGAGGTTTGCCACAAAAAATATTTCCACTGGGAGATGAATTTGGGAGCGCTAAATCTTTCACCAGTAATATTCCATCCTCTTCACTGTATGTAAGATCACTTCTATGTGTAAACCTGTAAAACCAATGACAATGAGTCTGAGTGTCCTTTCTTTTACCCTGGAGTATTTTGCCATCTCTCTCTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTTTCTTTTCCTAAGACAGTTCTCCATTAATTCCCTCTGTTTATCTTTCTCATCGACTTCCTCTCTCTGAAGACCAAGCCTGTAGCGTTTGCAGTGAGGACTAACGTTGGCTA[T/A]AACCCAGGCCCTAATGATGATGTGCCTGTTCAGGGCATGGCCATCTCTTTCGAACCCAAAGACTTCCTGCACATCAAAGAGGTCAGACAAGCACACTTACCTTACCTTAAAATGTGTTGAAAGCATTTTGGCTTTCACCTGTAAAATGACAGATGTTCCTGAAGTAATAGTTTAAGAAATCACACTGTTATGACAGCAAAAAAAATAAGTTTGTGATCAATCTTCATTTTATTGCCCAATCAGATGATGTGCTGCACCTCTTAAGTGTTTAATTTGGCTTACATTTCTTTGAAAGGGGGTGTTTTTTTAAACTAATTGGCTACATTTTCAAATATCTTTAATTTGCTTAGTTTGTTTCTGTAATCTGATGTATGATTGAAGCCTTCTTTAATATATTTATAGGTATATTTTCTTATATTGATGGTAAATGTATCTGCTGCTTAAACGTGATTCAAAGGCTGGGTGTTTTCTGTTAACAGAAGTATAATAATGACTGGTGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8705
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000012835 Nonsense 241 520 7 14
ENSDART00000057159 None None 603 None 14
ENSDART00000111707 None None 478 None 13
ENSDART00000123068 Nonsense 241 642 7 14
ENSDART00000130611 Nonsense 241 517 7 13

The following transcripts of ENSDARG00000002167 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 3 (position 15800732)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 16030951
GRCz11 3 16180751
KASP Assay ID:
2259-3197.1 (used for ordering genotyping assays)
KASP Sequence:
ATGTTGAGGAGGCGGAGACTGCCGACACCCGCGACCATAAGGGTGTGGGC[G/T]GAAGTGTCACCTCCCCTCAAGGCAACCTGCCCCGCCTCCCTTTCTTTAAR
Long Flanking Sequence:
AAATGAGAGACCCATTTCCTCAAGCGAGAATGATGTCGGCTAAAACTTGGTCGTACACCATTGGTACCCTTTTGGCAGTGGAAACGCAAGCCTGATAAAGGTGACCCATACCAACTCGTACAATGTCATACTGTACCACTCAGTGGAAAAGGGCCATTAGTAGTCCATGAAAAAGGTCATTTCTTTTCAGTTTTGCTTGTCCTTCATTTTTATAGCACGTTCTGTGTTCTCTTCATCACCTTTCTGACTCTGCCAAGTCTATACATCATGCTGCTGTTTCTCCTCTCTTCCTCTTCTCTCGTTTTCTGTCCATTACCCCTGTGTCCCTGTTCTATCGCTCCTTCTCTATCTCTCTCTCCTGTTGTATCCTCCCATTAAACCCCGTCTACCTCCCCATGGGTCCCGTAGCTGACTTGTCCTCGGGGCTTTATGACGATGCTTTGGATTCGGATGTTGAGGAGGCGGAGACTGCCGACACCCGCGACCATAAGGGTGTGGGC[G/T]GAAGTGTCACCTCCCCTCAAGGCAACCTGCCCCGCCTCCCTTTCTTTAAGAAGGTAACCTGGAGATGAATGCATCATTAGACGCCAGCCTCCTTCACGAGTGACTAATAATCAGACCCTTCCTAACCCAGCACTTTCTGTGTCTCAATGTGGGTGGTCTTTGCTGTTTGTGGACATTTGTTTGTGCTTAAATTCGCATCTTAGAAATATTAGTTCAATAGGTAAAAAGAAACTCATCATTTACTCACCCTGTGTTTAAGAAAAAGTTATAATTTTTCAATCAATTTTCAGTTTTTTCCTAATATAGGAGACTGAGTGAACAGTTTATTTTTGTTTACTTATTCAAAAATACATTAAAAATAATAATTTGAACAAAACTGATTTAAACATGCATATAATTAGATTTGAGAGTTTCTAAGTGATATATGCAGTGGTTTATGATATATTTAATATATGCATTCTCAGATGTACAGTGGGAGAAAGAAGTATTCAACACGTGAT
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa26021
Status:
Less stringent filtering
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000012835 Nonsense 338 520 10 14
ENSDART00000057159 Nonsense 299 603 10 14
ENSDART00000111707 Nonsense 299 478 10 13
ENSDART00000123068 Nonsense 338 642 10 14
ENSDART00000130611 Nonsense 338 517 10 13

The following transcripts of ENSDARG00000002167 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 3 (position 15791524)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 16021743
GRCz11 3 16171543
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCGTCCTTAACAACCCCAGCAAACACACCATCATCGAGCGCTCCAGCACC[A/T]GATCCAGCCTGGGTACGAAACACACCTGCACATAAAATGAGAAATGAATA
Long Flanking Sequence:
AAGGCTATGAGGCAAGACTGCACTTCTCTCAGAAATTGGCAATTTATTATTGTAGTCATGTTGTTTATGCTCATATTGTGTGTGTGCGTGCGTGCGTGCGTGCGTGCGTGCGTGCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTGCAGGTCACAGATATGATGCAGAAAGCTCTCTTCGACTTTCTAAAACACAAATTTGAGGGCAGGTGGGTACCATAATGTGCATGCCATGATTATAATGAATAATAGACTTCTTCTCATCACTATGGCATTGATAAACATTTAGGTAACATTACAGCTCTGTGCAGATCATTCATGATGGAAATATCACAGCGCACTCATGCTATAATTGGAATAGCGTGGTTATGAATTATTGTTTGTTCCAGAATATCCATCACCCGGGTGACAGCCGACATCTCACTTGCCAAACGCTCCGTCCTTAACAACCCCAGCAAACACACCATCATCGAGCGCTCCAGCACC[A/T]GATCCAGCCTGGGTACGAAACACACCTGCACATAAAATGAGAAATGAATAACTGCTTCTGAAGAGCGCCCTCGTGTGGCAGAAAATGAATGACAAGATATGACAACATATTCTGGATAAAAGAGCACACAAAATGTGACCTGTTTACATTGAGAGCAAAACACACACAAAAAGTAATAGAATAAAAAGGCTTACTGATCATAAAACTGGTATACCGAATATGTTTAAGTCAGAAGCATAATGTATATTTATAAAACATTAAAAATCTTATATGTTTGTAATTAAATTTAATTATGAATATGAAAAGCAACTGAACAGAAAATAATAAGCAATATTTACAGTGCATCTAGAAAGTATTCACAGCGCTTAAATTTTTACACATTTTGTTATGTTACAGCCTAATTCCAGAATAAATTAAATGTATGTATTTCCTCAAAATTCTACACACAATACCCCATAATGGCCTAAAAATGTGAAAAAAGAGTTTTTGAAATTGTTGCA
Associated Phenotype:
Not determined