Busch Lab

ZMP

pcl

Ensembl ID:
ENSDARG00000000972
ZFIN IDs:
ZDB-GENE-051120-144, ZDB-GENE-090908-3
Description:
hypothetical protein LOC553283 [Source:RefSeq peptide;Acc:NP_001032759]
Human Orthologue:
PC
Human Description:
pyruvate carboxylase [Source:HGNC Symbol;Acc:8636]
Mouse Orthologue:
Pcx
Mouse Description:
pyruvate carboxylase Gene [Source:MGI Symbol;Acc:MGI:97520]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa16065 Nonsense Available for shipment Available now
sa23952 Nonsense Available for shipment Available now
sa37328 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa16065
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000001098 Nonsense 204 1181 4 20
ENSDART00000028401 Nonsense 204 229 5 5
ENSDART00000131874 None None 784 None 12
Genomic Location (Zv9):
Chromosome 21 (position 26151400)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 26720238
GRCz11 21 26756933
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACAGCTACGGCTTCCCCATTATCTTCAAGGCTGCGTACGGTGGTGGGGGA[C/T]GAGGAATGCGGGTGGTCAGAGAGTATGAGGTACCGTGTCTTAGATTAAAA
Long Flanking Sequence:
ACGTTATCATAGAAGGAAATATTTTGTTCAATTTTGTATGCTTAATTAAAATATGGATGATCTTTATATACTTTTTGGTAATTGTGTAAATTCTTCCAATAAATAAAATAAATGAACTAATGGCTTAAATGCACATATAAACATGATTAACAACCTTTAAGCGTTAAGCTGTCAGATCTTTAACAGTTTACAACTTTCTAAAACTGTAATCCCATATTGCGAAAATTAATACCATTTATTTTAACTTCCAAAACACAATTGTTGCACCCAATTTAAAGTGGAAGCGTTATAAATCATGTTGTAAAATTGACATGATAACCTGACTTAATTTGAAAGGTTGCAGGTTTGATTCCTGGGCAAACAAATTTTCTGTTCATCTTGCAGGAGTGCCGGTGGTTCCTGGGACAGACGCTCCCATCTCCTGTTTGCAGGAAGCTCAAGAGTTCTCCAACAGCTACGGCTTCCCCATTATCTTCAAGGCTGCGTACGGTGGTGGGGGA[C/T]GAGGAATGCGGGTGGTCAGAGAGTATGAGGTACCGTGTCTTAGATTAAAATTATTAGTTGGGGTTCATAATCTTGTTTAATCTCTGTTCAATTCCTTCCAAGTTGAGGTTTGATAAAGGGGGGCTTTTAAATGAGCGCAAAAGTGAGCACCCGTTTGCCCTTTAGATTTGTTTGCTGTTCAGTTACTGGTGCTGTATGAATTAGTGTGTTGGGTATTTGCGCTGGGTGACCCGGTCACTGTGTGTGTGTGCTTGTGATCAGGAACTAGAAGAGAACTATCAGCGGGCGTACTCTGAAGCCCTGGCAGCCTTTGGCAATGGAGCTCTGTTTGTGGAGAAGTTCATTGAGAAACCCAGACACATCGAGGTGCAGATCCTGGGTAAGTGAGGTTGTTGTTGGTGTGTGTTTTTCTGTAGTGGAAAAAAAAGCATTGATATATAAAAAAATAAAAATAAAATAAAAAGCCTAAATATTTTACAGTCTGGGATGATTTACTCAAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23952
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000001098 Nonsense 1015 1181 18 20
ENSDART00000028401 None None 229 None 5
ENSDART00000131874 Nonsense 618 784 10 12
Genomic Location (Zv9):
Chromosome 21 (position 26355538)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 26924449
GRCz11 21 26961144
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCTCACGGTGACGAAATCACTCCAGAGGATGTGATGTCAGCAGCCATGTA[T/A]CCCAAAGTATTCCAGGAGTTCAAGGATTTCACCAGAACCTTTGGGCCTGT
Long Flanking Sequence:
TGATTGAGAATCCTTGATGGCAAGTTTTTGCCTAAGAACCCATCATAGTCAGTGAACTGTGGAAGAGACAGAAAAAGAGTGGAAGAAGATCACTGCAGAGCAGTGTGATGTCCACGAATGTGCTCAATTCATTCAAAGCAGTGGCCCCTTTAGAAATATTAGTTTCAATCATTCTTCATGCTACAATCATTGCGGTTCTCTCATGTTTCCACAAGGTAAAGGCTTTTTATTAAAGTTATTTTGCAAAACTATATAGTGCAACTAAAATTCCCTCCATTTTCTAACCATGAAGACTGTTATTTCTGAGAAAATGTGTTTATTAATTGTTCTTTAAGTTTCTCTTTTGTTTTTATTGTTTAGGTTTTGAAGTCACTTCCCCGTGTCGAAGGACGTCCTGGAGCCTCTCTGCCTGCCATGGATTTCCAGGCCTTGGAGAAGCAACTGAAAGATGCTCACGGTGACGAAATCACTCCAGAGGATGTGATGTCAGCAGCCATGTA[T/A]CCCAAAGTATTCCAGGAGTTCAAGGATTTCACCAGAACCTTTGGGCCTGTGGATTGTTTGGATACCAGACTCTTCCTAGACGGACCAAAAATTGCTGAAGAGTTTGAGGTGGGAGTATTTCAGTCTTTCAATTATTTAACGGAAGTGGCATCAAATTTTTATTCTCAGTTGCCCTGTCATAAATCTTCCTGTCAGCCATGATTGTACATGTCATTCCTACATTCCAGGCATCAGTTGTGTATTTCCTCTGCTCATATCTGTGCTGTCTGTCTCAGGTGGAGCTGGAGCGAGGAAAGACACTTCACATCAAGGCTCTGGCTCTGGGAGATCTTAATAAAGCGGGGCAGAGAGAGGTGTTCTTTGAGCTCAACGGTCAGCTGAGATCTGTTCTGGTCAAAGACACCGTGGCCATGAAGGTGGGTTTCTGAATTTCACTTACAGCTTTTAGGGAAGTTTTCCCCTTTTTTTAGTGACAGTTAGTGAAATGTCTCCTGACCAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37328
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000001098 Nonsense 1137 1181 20 20
ENSDART00000028401 None None 229 None 5
ENSDART00000131874 Nonsense 740 784 12 12
Genomic Location (Zv9):
Chromosome 21 (position 26360097)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 26929008
GRCz11 21 26965703
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTAAGGTGGTGGAGGTGAAAGTGAAGCAAGGGCAGCAAGTGGAGAAAGGA[C/T]AGCCGCTCTGCGTGCTCAGCGCCATGAAGATGGAAACGGTGGTCAACTCT
Long Flanking Sequence:
ATTTTTCTGTCTTTCAATCTGTCTATCTATCTGTCTGTCTATTCGTTTTTTGTTTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGGTTTTATTATATTCTGATATACTGTTTTCAATGATCCTCTAATGATCAACATGTATGCATTTCTTTTTAAAGAGTTTCTGAAGGTCGAATGCAAATTGTAAATGAACCGGACACCCCTGCTGACCTAAATCAATTTTCTTGGATTTGCAGGAGATGCATTTCCACCCTAAAGCCCTGAAGGACGTTCGTGGTCAGATCGGAGCTCCTATGCCCGGTAAGGTGGTGGAGGTGAAAGTGAAGCAAGGGCAGCAAGTGGAGAAAGGA[C/T]AGCCGCTCTGCGTGCTCAGCGCCATGAAGATGGAAACGGTGGTCAACTCTCCCATCTCCGGCACCGTGGCCAAGATCTACGTGACCGCCGACAGCACACTTGAAGGAGATGATCTTATTCTGGAGATCACCGAGTAGATATCACGAAAGCCAACAGCAGGGAACATAACACATCACCACTGCCAATCCCTGCACGGCTAAACACACATACACGCACACATGGAGGCTGACAGTAGAAGCTGTAGCACTAGTACAAGCACAGATTACAAATTACAGATATTTTTACAGGATCTCAAAGAACAACACATCACAAATCTGCAAATGTCAAGCGTGAATTCTTTGGCATTAGTGTCATGTGCTTTTGTGATCTTCAATCACATTTGTTATATTAATATGTGACGAGAATTTGTTCTAGTGTTGTTTTGTTAACAGAAATCTATCATTAGTATTAATGAATGTAGTGGAAACTAAACGATTGACATTGAAAACAAATAGATAGCA
Associated Phenotype:
Not determined