Busch Lab

ZMP

itsn1

Ensembl ID:
ENSDARG00000000086
ZFIN ID:
ZDB-GENE-030616-226
Description:
intersectin-1 [Source:RefSeq peptide;Acc:NP_997065]
Human Orthologue:
ITSN1
Human Description:
intersectin 1 (SH3 domain protein) [Source:HGNC Symbol;Acc:6183]
Mouse Orthologue:
Itsn1
Mouse Description:
intersectin 1 (SH3 domain protein 1A) Gene [Source:MGI Symbol;Acc:MGI:1338069]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa15350 Essential Splice Site Available for shipment Available now
sa32751 Nonsense Available for shipment Available now
sa25652 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa15350
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000000087 Essential Splice Site 264 1746 8 38
ENSDART00000132378 Essential Splice Site 240 1722 8 38
ENSDART00000139573 Essential Splice Site 240 1221 8 28
Genomic Location (Zv9):
Chromosome 1 (position 47552390)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 46364051
GRCz11 1 47055283
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTATTCTRATGCAGTCCAGTCTACCACAAGCCCAGCTGGCCACCATCTGG[T/C]GCGGATCCAACCTGTTTTTTCTTRCTCTGTCTCYGTCTCGCATTAAAAAC
Long Flanking Sequence:
TGAGTAATAATGATGCTGAAATTTCAGCATTGCCATCAAAGAAATCAATTACATTTTAAAATAAATGAAAATCGAACAGTTTTGTTAAAATTGTGTCAAAAGTAATTTACAAATATTACAGTGTTTACTATATATTTGTCATTAAATAAATGCAGCCTTGATACAGGTGAGACTTCAATTCATTTACTTTAATCAATCAGTTGATTCAGCATATTTTAATTTAATTTCAGTTTTGCACCATCCATATTTTTTTATGAAAATGGAGCTATATGATTTGCAGGTTTGCAAAAATGACTATGGTTTGCAGAATTCAGAGTTCTTGTCATGAGTGAAAGTGGTTAGTCAGAGCAGCTTAGAGGAAAGAGAGCTTTGCTGATTCAACACAACCAGCTTTGTTTCCCCCTTTCATTCTCTTTTTCTCCCTTTCTGCCTCAGGTCCACAAGCCAGAACTATTCTGATGCAGTCCAGTCTACCACAAGCCCAGCTGGCCACCATCTGG[T/C]GCGGATCCAACCTGTTTTTTCTTACTCTGTCTCCGTCTCGCATTAAAAACTCAAACAAATCTCTGAGTTCGGAGATTCGTATCAGTGTAAACACACGGATTGGTATCTGGTTATTGTTATGAGTAAATCCATCAGTTGTTTTGATTTCTTTTAACATGCTGTTCTCAGATCTGTGTATGGCCTAAGGCTTTGTTTACTCTTGATGTTAACACAGCTGAACTGCTCACACGTGGACCAGCATAATAAATCGCTGTTTTGCCGTCTACCTGTTTCTCCCTGTAGGAATCTGTCAGATATAGATCAGGATGGGAAGTTGACCGCTGAAGAGTTTATTTTGGCCATGCACTTGATCGACATGGCCATGTCTGGTCTCCCTCTTCCCCCTTTGCTGCCGCCTGACCTTATACCTCCAACATTCAGGTGAGAGACTTCGACCAAACAAAACTAAAGTTACTCTGTTAGGCCTTGATCACACCAAACACACTTTTTGCATTGAGAGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32751
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000000087 Nonsense 546 1746 14 38
ENSDART00000132378 Nonsense 522 1722 14 38
ENSDART00000139573 Nonsense 522 1221 14 28
Genomic Location (Zv9):
Chromosome 1 (position 47540995)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 46352656
GRCz11 1 47043888
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATTAGGAGTCTCAGCAGTGGTTGAGTCGCTTGATTCCTGATAAACAGTG[T/A]CTGAATGACCAGCTGAAGCAGGTTCAGCAGAACAGTCTGCACAGTAAGAG
Long Flanking Sequence:
TCCTGCTGGAAGTAGCCATCAGAAGATGAGTACACTGTGGTCATAAAGGGATGGACATGGTCAGCAATGATACACAGGTAGGCTGTAGCAGAGACATGATGCTCAATTGTTAATAATGGGACAAAAGTGTGCCAAGAAAATGTATCCCCGTGTCATTACACCACTCCACCACCAGCCTGAACTGTTGATACAAGGCAGGATGGATCTAAATTCTGACCCTACCATCTGAATGTTGCAGCAGAAATCGAGACCAAGCAAAGATTTTCCAATCTTCTATTGTCTAATTTGTACAAACTTTTATTTTGGATGCAATTAATTGTTGCCGAGCACTTGTATGCATGTAGGTCTGTGTGTATATGTGCGAATAGATAACAGGATTCAAATTGTTCTGTGTATAAATGTTTCCAAGTAATCAGAGAATTTTATAAGTTTTCTCTCTTTTTTTTTCCTCATTAGGAGTCTCAGCAGTGGTTGAGTCGCTTGATTCCTGATAAACAGTG[T/A]CTGAATGACCAGCTGAAGCAGGTTCAGCAGAACAGTCTGCACAGTAAGAGCATTTTCCTCAGTGCAGTTTTCAGTTCATGTCTAGCTCAGTGTAAAAAAAAGCTACTTAAAAGAGCTTGGAAAGCTGTAAGCATTATGGGGCAAAGCAGGAGTAAAAAAAGGAAAACTGCTATCTGTCAGTGGCCCATACTGACTTGAGTATCTAAAGTAAATTGAGTAGAAATGCAAGATGTTTATATTTAAGGAGTGCTTATTTTAAATTTAGGCACACAACGGGATTAGGCTCGGGAACTAGAGCATTTGAAATTTGTATTTTTATCAGTGTTTGAGTGCTGTGTCAATCTGCTAACGGATCCGCTGATAGACTCTGCTTTCAAATGCTTCAGTGTCTAAGTGCTCTTGTAAACTGGTGATTATTAAAGCCAATCACAGTCATATCTGCTTTGTTTGTAAACACAATGGCCATTTAGCAGTGTTTGTAGATCAAATAAAAAAATATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa25652
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000000087 Nonsense 1217 1746 27 38
ENSDART00000132378 Nonsense 1193 1722 27 38
ENSDART00000139573 Nonsense 1193 1221 27 28
Genomic Location (Zv9):
Chromosome 1 (position 47517055)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 46328716
GRCz11 1 47019948
KASP Assay ID:
2259-1008.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCGGGAAGGGCCAAATCATCAATGTGTTGAGCAGAGAGGATCCCGATTG[G/A]TGGAAAGGAGAGTTGAATGGATCCGTCGGCCTCTTCCCCTCGAACTACGT
Long Flanking Sequence:
CCACGTTATTGGAAATAGCCTCATTTTATGACTTCCCTAGAGTTAAACAGTTTTACCATTTTTTTAATACACTCAGCTGATCTCCACGTCCAGTGGGAGCAAAAATAAAAATATAAAAATAAACAAAAAAAAGGTTTTGATAATAATTTCTATACAAGCTTGACTCTTCTGTAGTTACATCGTGTTCTAAAGTCGATCTACTCATACAGAAGTCCAATTCAACACAAACCCACATTTGCATGTTTTGCTTGTTTGTCTTCAATTGCATCAAATAAATGACCTGGGAATCAAATATTTTAGATAAAAATAGCGTGACCTACTGTATATAGCTTGGAAAATATGCTTGAGCATTACAATACATTTATACATATGCATTTGTGTTTCCTCTTTGCAGTGTGCCAGGTGATTGGCATGTATGATTACACTGCTCAGAATGATGACGAGCTGCCTTTCGGGAAGGGCCAAATCATCAATGTGTTGAGCAGAGAGGATCCCGATTG[G/A]TGGAAAGGAGAGTTGAATGGATCCGTCGGCCTCTTCCCCTCGAACTACGTCAAGCTGACCACCGACACAGACCCCAGCCAACAATGTGAGTCCAAAATGCTCTCCTGTATCTTACACACACACAGTTACACTGATCTTTCATCTATCTTGCTCAAAAGAGATGTAGATCAATTTCTCTTTAAAGAGACAATTGGCTTGCGTCACCAATAGCATCCGATTAAATGAACCGTGCCACTCTGATCCAAAGCTACTACTTTCAAATCTTTGAGGACCTTCTTCGATTTAGTTTAGCCATGTCCTCACAGTGTGGTGAGGTTTAAAACGTCCAATGTCCAATCCTTATCCTCTGCCACAATGAAGCCCCTCCTCTTCCTGTTTCCAAGCAACCTCTCACCTCATGTTGTAGAGCATTAAGTAGAACCTCACCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGCCT
Associated Phenotype:
Not determined