ZMP

dyrk1ab

Ensembl ID:

ENSDARG00000023814

ZFIN IDs:

ZDB-GENE-030131-5677, ZDB-GENE-030131-5677

Description:

Dual-specificity tyrosine-regulated kinase 1ab [Source:UniProtKB/TrEMBL;Acc:A9QVW5]

Human Orthologue:

DYRK1A

Human Description:

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A [Source:HGNC Symbol;Acc:3091]

Mouse Orthologue:

Dyrk1a

Mouse Description:

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a Gene [Source:MGI Symbol;Acc:MGI:13

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa9999	Essential Splice Site	Available for shipment	Available now
sa28438	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa9999

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000010954	Essential Splice Site	383	395	8	9
ENSDART00000054416	Essential Splice Site	404	734	7	11

Genomic Location (Zv9):

Chromosome 15 (position 18853410)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	15	19956036
GRCz11	15	19891768

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

GCTGTCAGATGGAACATGGAGTATTAAGAAGACCAAAGATGGAAAAAGGG[T/A]ATGTGCTGCTAATATTTTAAAGAGAAATTACCATCAGGTGATTTCTGCTG

Long Flanking Sequence:

ATTCTACCGCTCCCCTGAAGTGTTATTGGGAATGCCATATGACCTGGCCATAGATATGTGGTCTCTGGGCTGTATTCTGGTGGAAATGCACACAGGAGAACCTTTATTTAGTGGAGCCAATGAGGTAATGAATTATTATTACCCAAATCCCTAAACTTCACAAATGTCAACTTTTAGGATTGACAGTCACTATTTAAATGTGGAAATGAATTCCCTAAAAAAAATGTGTGTATTGATATGTGCACAGAATTATGGGGTAATGCCATAGTTGACTGACTCTACAAAATTTAAACTGACAGTTACAGGACTCAATTATTTACCATAACATTGCTTATCATTTTAAATGAAATTCCATCAGGTGGACCAAATGAACAAAATTGTTGAAGTACTTGGGATCCCACCCAATCACATTATGGACCTAGCACCAAAAGCCAGGAAGTTTTTTGAAAAGCTGTCAGATGGAACATGGAGTATTAAGAAGACCAAAGATGGAAAAAGGG[T/A]ATGTGCTGCTAATATTTTAAAGAGAAATTACCATCAGGTGATTTCTGCTGGAATGCTTGTTATTTTTCTTGTAAGTGCTAGAGTGTCTCTCTGCTTTTCTGCAAGCAGTACAAACCTCCGGCATCTCGAAAGCTCCATGCCATCTTGGGAGTGGAATGCGGTGGACCAGGTGGTCGTCGGGCGGGAGAATCTGGCCACGCAGTAGCTGACTACTTGAAGTTCAAGGACCTCATTCTCAGAATGCTGGACTATGACCCCAAGACGCGGATTCAGCCCTACTATGCCCTCCAGCACAGTTTCTTCAAGAAAACGACGGATGAAGGAACCAATACAAGCAGTAGTGTGTCAACAAGTCCTGCACTTGAGCAGTCGCAGTCATCAGGGACCACTTCTAGTACATCCTCAAGCTCAGGTGCTGCTACCCGTTCTGTGTTCTAAACTTTTTTTTTTTAAACAATATCTCCTAAACCTTTAAATACAAACCCGTTATGTGCCCTGAC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa28438

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000010954	None	None	395	None	9
ENSDART00000054416	Nonsense	604	734	11	11

Genomic Location (Zv9):

Chromosome 15 (position 18855127)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	15	19957753
GRCz11	15	19893485

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CCACCACGGACAGGTCATTGCAACGCGACCACGGCCACGACTCTACAACT[C/A]GCCCACCAACAGCGCCTCCACCCAGGATTCCATGGAGGTGGTGCACGGTC

Long Flanking Sequence:

AAAACTGGCTTGATCATTGTAGTGTCTCTGAGTGAAGCTAAACACTGTTTGTTTGCCTTATTTCCAGGAGGATCATCTGGAACAAGCACCAGTGGCAGAGCAAGATCCGATCCAACTCACCACCATCGGCACAGCAGCGGGCATTTCGGCACAGCTATGCCAGCCATAGACTGTGACAACCTGTGCCCTCAGGTGAGCCCCTGTGGCTTCTCTTGTCAAGTGGTTAAAGCGATTCAGAGTTTGACCTTTCTCACCGAACAGTGCTTTTTTCTGTTTCTGGTTTGTGCAGGCGAGACAGCCTTATCATCCACCAGTTGTATGGCCTGGAATCGTAGGACCAGAACCTGTCACTGTAGAGACTCATCCAGTCCAGGAAACCACTTTTCATGTGCCTCCCCAGCATCCCAAGGCATTGCACCCCCATCACCATCACCACCACCATCATCACCACCACCACGGACAGGTCATTGCAACGCGACCACGGCCACGACTCTACAACT[C/A]GCCCACCAACAGCGCCTCCACCCAGGATTCCATGGAGGTGGTGCACGGTCATCTGTCCATGACATCTCTGTCTTCCTCAGCATCCTCTTCCTCCACATCTTCCTCTTCCACAGGAAACCACGGCAACCAGGCTTACCAGCTCCGCCATCTTCCTGCCAACACCCTGGACTTTAGCCAAAACGGAAGTTTAAGTATGAGTATGGGTTTGGGTGCCTTCTCAAATCCCCGCCAAGAGACTGGTATGGCTGGAAATCCCACGTACCCCGTTGCCACAAACACAGGAACTGGTCACTTTATAGCAGAGGGACACCTGGGCATGAGACAAGGCATTGATAGGGAAGATTCTCCAATGACTGGAGTCTGTGTTCAGCAGAGCTCGATGGCCAGCTCGTGACTTTAGCTGAAATTGGTTTGTTTTGTTTTCTGTGTGATTTTTTTTTTTTTGTTTGTTTCTTTTGTTTGTTTGTTTTTTTTTTAATGGTGGTGTTTTCATTTTCTGT

Associated Phenotype:

Not determined