ZMP
frem3
Ensembl ID:
ZFIN ID:
Description:
Fras1 related extracellular matrix 3 [Source:RefSeq peptide;Acc:NP_001131131]
Human Orthologue:
FREM3
Human Description:
FRAS1 related extracellular matrix 3 [Source:HGNC Symbol;Acc:25172]
Mouse Orthologue:
Frem3
Mouse Description:
Fras1 related extracellular matrix protein 3 Gene [Source:MGI Symbol;Acc:MGI:2685641]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa39642 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa19528 | Nonsense | Available for shipment | Available now |
| sa9807 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa39642
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000114228 | Nonsense | 140 | 3127 | 1 | 24 |
| ENSDART00000142154 | Nonsense | 88 | 3075 | 1 | 24 |
The following transcripts of ENSDARG00000074677 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 1 (position 35361414)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 34921272 |
| GRCz11 | 1 | 35653299 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTGGTTCCCGGAGCCCAAGCAAAGACCACATAAAACTGCAACTGAGGTA[T/G]GACTCTAACACAGACACAGTGGTGGTCCCTTTAATTCTTGAAGTAGAAGT
Long Flanking Sequence:
TCATACTGCATTGCAGTGATTTTTTTTTCTTTCTTTTTTCTTTTATTTTTGCAAGTTCATGCAGTCCAACTAGCTGTAGATATGGCTGGTTGTCTGCAAAGAGGAAGGCTAAATACAGCAGAAACACCTCTGAAGTGCCTGTTAATATTGATTTCTTTAGGATGTTGTCTCTCTAAAGTGAATGCAGATCCTTTCGACGCCGCTTTTCGACACAGTCATCGACATGGACCTACCTCTGAAACAATCTTGGTAGCCAACAATGGGATTAGAGTTCCCTTTGGACGCTCAGTATATCTGGACCCTATCAATGACCTTGTGACTGAAGTGTATGCAGGAGACCGCTGTTACATTACAGTGCTAGACAATGACCCACTGGCTCAGAGACCTGGAATGTTAACACCAAAGAAGTTCCCGTGCGCTTTTGGAGCAGAAGAGGTGAAATATACTCATTTTGGTTCCCGGAGCCCAAGCAAAGACCACATAAAACTGCAACTGAGGTA[T/G]GACTCTAACACAGACACAGTGGTGGTCCCTTTAATTCTTGAAGTAGAAGTGGTTTTTCAGCAACTGGAGATTCTCACTCGTAACATGCCTCTTGTTGTGGACAAGCTCAACGGGGTAAGCAACCCAATTGACAAAAAAACTCTGGAGTTTGCATTTGAAGATGGTGTCACTACATGCAAGGTGACCACACTTGTTGGAGCAGGCAAACTACCCAGGTATGGTAGTCTAACTGATAACTCTGTTAATGGCCAGATGATTAACTGTGATGATTTTGTTAAGAAGGGAATTCAGTATCAGCACACCGCAACTACCAACTCTCCAAACAGAGACTACATTCCTATGCTAGTAGAGGTACAAGATAATGACGGTAATACTATTCAACAAGAACATTTTCAGATAATGGTTAGAATCAAAGAGGGTACTGAAAATACACAACCAAAGCCTAGCTTTATATCTATGATGATGATGGAGATTGACCAATTTGTGATGACCGCCATTAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa19528
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000114228 | Nonsense | 1339 | 3127 | 1 | 24 |
| ENSDART00000142154 | Nonsense | 1287 | 3075 | 1 | 24 |
The following transcripts of ENSDARG00000074677 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 1 (position 35357819)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 34917677 |
| GRCz11 | 1 | 35649704 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTACTCAAGATGAACTGGACAAACAGTTGATTCAGTATGTTCACACAGGT[C/T]AGGAGGGTGTGCGTGACCTGCTAAAATTTGATGTCACTGATGGAATCAAT
Long Flanking Sequence:
CAAGTGATGAATTAGTTTTTGAAATTCTGAAAAACCCAAAACATGGAGACATAGTTCAGCAATTGAGCACTGGGACAGTTCCGGTGGTGAAATTTACCCTAGAGCAAATCAAGGAGGCTTCCAATATTGTTTATGAGCATGACGACTCTGAAACCAAGGAAGACAGTTTTGAAATTCGACTCACTGATGGAAAGCACACTGTTGAGGAGAAGGTCATCATAATTGTCATTCCTGTAGATGATGAAACTCCAAGGATGGCCATTAACGATGGCCTGGAGGTAGAAATTGGAGAAACTAAAGTAATTAGCAATAGAGTCCTGAAGGCCACAGATCTGGATTCCGAGGACAAAGAACTTACTTACATTGTGCGCTATGGCCCTGGTCAAGGCTACCTTCAAAGAATTACCAAGCATGGAGTTGTCATCGGCAATGTTAGTACTGGAATGAATTTTACTCAAGATGAACTGGACAAACAGTTGATTCAGTATGTTCACACAGGT[C/T]AGGAGGGTGTGCGTGACCTGCTAAAATTTGATGTCACTGATGGAATCAATCCCCTTATTGATCGCTATTTCTACATTAATATTGGCAGCATGGACATGGTTTTTCCTGATGTTATTAACAAGGGTGTGACTCTCAAAGAAGGAGGTAAAGTCACCTTGACCACAGACCTTCTCAGCACAACCGACATCAACAGTCCAGATGAATATCTTAGCTTTAGCATTACTCGTGCTCCTAGCAGGGGCCACCTTGAAAGTACTGATCTCCCGGGGGTGCCCATCTCAACCTTTACTCAGCTACAGCTAGCTGGCAACAAGATCTACTACATCCATACATCTGATGATGAAGTTAAGATGGACAGCTTTGAATTTGAGGTGACAGACGGTTATAACCCAGTTTTTCGCACTTTCCGTGTATCTATTACAGATGTAGACAACAAGAAGCCAGTTTTAACAATCAACAAGCTAGTTCTGGGGGAGGGAGAAGCCAAGCTTATCACACCC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa9807
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000114228 | Essential Splice Site | 2843 | 3127 | None | 24 |
| ENSDART00000142154 | Essential Splice Site | 2791 | 3075 | None | 24 |
The following transcripts of ENSDARG00000074677 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 1 (position 35325879)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 34885737 |
| GRCz11 | 1 | 35617764 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GATGGCTCGGTGGATTTTGGAGAGGGCACAGACACTGCCTTTATGGAAGG[T/C]ACTGAACAGCATTTTATTTTAACCTAATTTTAGGTGAAAGACCTAAACTA
Long Flanking Sequence:
ACAACGGCAGAAAAACAAGACACGTTAAAAGACTCTCTTTAAAGATCACCATGTAATTGTCAAGTAAATTCTTTTTCTTTATACCACTATCATTCAAACCACTGGGTTTTACAAATTTGTTAAGACATTTTTTATAGTTTGAAATAAAATAATGTAGTAATGTTCCTACTCCTCTTATAGGTTTTTAATAAGATCAGTGTTTGTGTGTTGTATTTGTGTTACTGACTGACTTTGGAACATTTTTTTCATCATTTTTATTTTATTTTCGCTGAAATATAGGCTTTCTATGTGTCTTTATTTTGTCCATTTAAATTGACGTATACACCAGAATACATAAACCACTGCTTCTATGGTATTTGTGCTGTTTGTCAGGTGAGTGACCCTGTGGCAGCAGAGTTTAGCTTGAACACACAGATGTTCCTGCTGTCGAAGAAGGAGATGTGGCTGTCTGATGGCTCGGTGGATTTTGGAGAGGGCACAGACACTGCCTTTATGGAAGG[T/C]ACTGAACAGCATTTTATTTTAACCTAATTTTAGGTGAAAGACCTAAACTATTATTTAGCATTTTAATATTATTGACTGACCTTATTGCTGTTGGTTTCCCTCTAGGTTCTAACATCTATGGGCGCGTGATGGTGGACCCGGTGCAGAACCTCGGAGAATCTTTCTCCTGCAGCATAGAGAAAGTTTTCCTCTGTACCGGGACAGATGGCTATGTGCCAAAGTACAACCCCACCAATAAAGAGTATGGATGCCTGGCTGATGCGCCATCCCTCCTTTACAGGCTCAAGATTCTGGTATGTCATTTTTCCATTGTTTTACCTTTACAAAACAGACATTGTGAATGTGGATCTTGATGTGTATTGAGGAAAATTAAAGTGTCAATCATACCGTTTATAAGGTCCATGATATAGATTCAGTTATGATATCACAATACAATTTTCCATGAATAATGTGGTTTTATATGACTTAGAATTGAACTTGTACATTATTTCCAGAAGTTA
Associated Phenotype:
Not determined