ZMP

si:ch73-33i10.5

Ensembl ID:

ENSDARG00000070565

ZFIN ID:

ZDB-GENE-100922-23

Human Orthologue:

ADAP2

Human Description:

ArfGAP with dual PH domains 2 [Source:HGNC Symbol;Acc:16487]

Mouse Orthologue:

Adap2

Mouse Description:

ArfGAP with dual PH domains 2 Gene [Source:MGI Symbol;Acc:MGI:2663075]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa6893	Essential Splice Site, Splice Site	Mutation detected in F1 DNA	Not yet available
sa9788	Nonsense	Available for shipment	Available now
sa40066	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa6893

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > C

Consequence:

Essential Splice Site, Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000103729	Essential Splice Site	30	382	2	11
ENSDART00000131288	Splice Site	None	378	None	11

The following transcripts of ENSDARG00000070565 do not overlap with this mutation:

ENSDART00000139657

Genomic Location (Zv9):

Chromosome 3 (position 26764624)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	3	26139612
GRCz11	3	26270483

KASP Assay ID:

554-5359.1 (used for ordering genotyping assays)

KASP Sequence:

TTTTTTTCATTAACTCTGATGTATAAATTTGCATGCATTTTTTTTNCTTTT[G/C]AAGATCCAGATTGGGCTTCATGTAARTTAGGAATATTTGTGTGTCTAACC

Long Flanking Sequence:

AATAACTCATTTCTAATAACTGATTTATTTTATTTTTGCCATGATGACAGTAAATAATATTTTATTTGAAGTTTTTCAAGACACTTCCATAAAGCTTAAATTGACATTTAAAGGCTAGGTAGGTTGGGGTAATTAGGCAAGTTACTGTATAATGATGGTTTATTCTGTAGACTATCGAAAACAAATATAGCTTAAAGAGGCTAATAATTTTGTCCTTTAAATGGTTTAAAAAAAAAATTAAAAACTGCTTTTTTTCTAGCTGAAATAAAACAAATAAGACTTTCTCCAGAAGAAAAAATATTATCAGACATGCTGTGAAAATGTCTTTGCTCTGTTAAACATCATTTGGGAAATATTTATAAATGGGGAAAAAAATCAAAGGGGCGAATAATTCTGACTTTCTTCTTAATTCTGAATATATATATATATATATATATATATATATTTTTTTTTTTTTCATTAACTCTGATGTATAAATTTGCATGCATTTTTTTTCTTTT[G/C]AAGATCCAGATTGGGCTTCATGTAAGTTAGGAATATTTGTGTGTCTAACCTGCTCCGGAACTCATCGCAATCTTCCCACTATAAGTCGTATCAAGTCCATTCGCTTAGACTTCTGGGATGATGAACTTGTGCAGGTAAAAATGACTTTGTGCGCTACGATTTTTAATGATTAGCTCAGATGATGTGTTCATTTTTGTTTGGTTATCATTATTTAACATTTCATAACCTTGTGGTTACATTAAGTCATGAATGTGAACTATAATCACTATTTTGTTTCCTTTCAATGCATCATTGGATGAGAAGTTTATGAAAGCCAATGGAAACTGCTCTGCCAAAAACTTCTATGAGAAATGCGTGCCTGTCTTTTATTACAGGCCACATCCACATGATTGCGAGTAAGTTGTCCAGCTCTTTCCTGACTAAAAGTCCTGCATTATTTTACACCTGACATACTCTGTTAGTTTGTACCACAATAGAACAGATCGATGTGTTTATATTTT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa9788

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000103729	Nonsense	65	382	2	11
ENSDART00000131288	Nonsense	64	378	2	11

The following transcripts of ENSDARG00000070565 do not overlap with this mutation:

ENSDART00000139657

Genomic Location (Zv9):

Chromosome 3 (position 26764518)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	3	26139718
GRCz11	3	26270589

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

CGGAACTCATCGCAATCTTCCCACTATAAGTCGTATCAAGTCCATTCGCT[T/A]AGACTTCTGGGATGATGAACTTGTGCAGGTAAAAATKACYTTGTGCGCTA

Long Flanking Sequence:

TTTAAAGGCTAGGTAGGTTGGGGTAATTAGGCAAGTTACTGTATAATGATGGTTTATTCTGTAGACTATCGAAAACAAATATAGCTTAAAGAGGCTAATAATTTTGTCCTTTAAATGGTTTAAAAAAAAAATTAAAAACTGCTTTTTTTCTAGCTGAAATAAAACAAATAAGACTTTCTCCAGAAGAAAAAATATTATCAGACATGCTGTGAAAATGTCTTTGCTCTGTTAAACATCATTTGGGAAATATTTATAAATGGGGAAAAAAATCAAAGGGGCGAATAATTCTGACTTTCTTCTTAATTCTGAATATATATATATATATATATATATATATATTTTTTTTTTTTTCATTAACTCTGATGTATAAATTTGCATGCATTTTTTTTCTTTTGAAGATCCAGATTGGGCTTCATGTAAGTTAGGAATATTTGTGTGTCTAACCTGCTCCGGAACTCATCGCAATCTTCCCACTATAAGTCGTATCAAGTCCATTCGCT[T/A]AGACTTCTGGGATGATGAACTTGTGCAGGTAAAAATGACTTTGTGCGCTACGATTTTTAATGATTAGCTCAGATGATGTGTTCATTTTTGTTTGGTTATCATTATTTAACATTTCATAACCTTGTGGTTACATTAAGTCATGAATGTGAACTATAATCACTATTTTGTTTCCTTTCAATGCATCATTGGATGAGAAGTTTATGAAAGCCAATGGAAACTGCTCTGCCAAAAACTTCTATGAGAAATGCGTGCCTGTCTTTTATTACAGGCCACATCCACATGATTGCGAGTAAGTTGTCCAGCTCTTTCCTGACTAAAAGTCCTGCATTATTTTACACCTGACATACTCTGTTAGTTTGTACCACAATAGAACAGATCGATGTGTTTATATTTTTAAAGAGGGATAATTCACCCAAAAATGTAAATACTGGCATCATTTGCTCTTCAATTACTTGTTCCAAACCTTTATGGGTTTCTTTCTTGTTGAACACAAAAGCAAG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa40066

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000103729	Nonsense	355	382	10	11
ENSDART00000131288	Nonsense	351	378	10	11

The following transcripts of ENSDARG00000070565 do not overlap with this mutation:

ENSDART00000139657

Genomic Location (Zv9):

Chromosome 3 (position 26754017)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	3	26150219
GRCz11	3	26281090

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GACCGGCAGTTTGTCTTCATGTGTGAACAGGAGCGTGATCAAAGAGAGTG[G/A]GTGGAGGCCTTGAAAACCGTTATCTCGAAACCCATGATGCCACAAGATTA

Long Flanking Sequence:

GATTTGTTTTTCTGTTTTCTAATGAATAGTATTGTTGCTCAAACAACTAAAGACATTCAGTTACTGTATGTTGAGAGTGAATGTTTGTGTGTGTTAAACAGCAGCGAGAGCCATTCAAGAAAAGATGGTTCATCTTGGATTCAATGGACAGAAAACTACTCTATTTTAAAACACAGCTGGTATGACTTTTTCTTCTTTGCTTTTTTGTATTCTCTCTTTCCTAAAGAACCAGATTTAGCTCTCGTAATGTTTAGCAAAAGAAAAACATAAGTTTTATGTAACGTTATCATCTGCGTTACTCTTACGTTAATTTTTTTTATCCTAAAGGATGCCATTGAGCTTGGGGTTGTTTTCATTGGCTCAGAGAATCATGGCTATTCAGTGAGGGAGTGTGTTCCTAAAGGCACAAGAGGCAACAAATGGAAGTGCGGGGTAATTGTGGAGACGCCGGACCGGCAGTTTGTCTTCATGTGTGAACAGGAGCGTGATCAAAGAGAGTG[G/A]GTGGAGGCCTTGAAAACCGTTATCTCGAAACCCATGATGCCACAAGATTACACCAGTAAGACTGTAATGATCTTTATCAGATGTGTGAATTAAATAATGCAAAACATGACTGAGCTGTGAACTAAAATACTCTGCTTCCTTTCAGCCGAAGCCAATATCCGTAGACGAAAGTGAATATAAGACTGCATGGGACAGTACGCTCAGAGGACACTGCTGGACTGTATATAGGGTCAAGCGTTTGAGTACCAGAGATATTTTATTCAAAGGGAAGTTTGGAGGAATGTGACTGCTTTTCTCTTTTTTGGTGCATTTTGGGATGTGAAACCAAAATTGAAGTAGGTCAAGTGAGGACAGATCCACTGGTTGAGTTTTCCGAAGGTATGAAGGAAGATCTACAAGGAGAGATCCAGACACAAGCTTTGACTGAGGAGTCTTGTCTCTGTCTGGCGAGAGAGAACTGAACTAGACTCATGTGACGTGTGAGTCCTCATGCAGGAGCT

Associated Phenotype:

Not determined