Busch Lab

ZMP

rrp12

Ensembl ID:
ENSDARG00000022410
ZFIN ID:
ZDB-GENE-050706-182
Description:
RRP12-like protein [Source:RefSeq peptide;Acc:NP_001025447]
Human Orthologue:
RRP12
Human Description:
ribosomal RNA processing 12 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:29100]
Mouse Orthologue:
Rrp12
Mouse Description:
ribosomal RNA processing 12 homolog (S. cerevisiae) Gene [Source:MGI Symbol;Acc:MGI:2147437]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa42231 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa35526 Nonsense Mutation detected in F1 DNA Not yet available
sa9602 Nonsense Available for shipment Available now
sa8658 Nonsense Available for shipment Available now
sa13242 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa42231
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000034829 Essential Splice Site 471 1283 12 34
ENSDART00000134343 None None 100 None 5
ENSDART00000145887 None None 276 None 9

The following transcripts of ENSDARG00000022410 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 31581543)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 31227491
GRCz11 13 31357941
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AACCAAACACGTCATCTGGAAATGGGGCTTGCGTTCTGAAAATGTTTCAG[T/A]AAGCTACCTGTGACCCTATACCCCCCTACCCCACTTCCTCACTTGTCATA
Long Flanking Sequence:
TTTTTCACTATGGAAGTCAATAGTTACAGGTTTTCAGCTTTCCTTAAAATAACTTATTTTGTGTTCACCAAAATAAAGACACTCATAAAGGTTTGGAACCACTTAAGAATGAGTAAATGGTGAATAAATTTTCATCTTTATAAACACATGCAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAAATATATTGACTCTTATCATGGGATGAATGTGCGATGGCTCCAAACGGACATGTTATCTTAGCTGGGGTGCTTGTTTGACTGTAACCCTAGACATTGTTGATGCTGAAGCGATATTGTGCAGCCCGAGTTCATTTCTGTACATTCTAAGAAAGATTTTTTTTCTTCTCTCTAGACTCTGATAAATGACTGTGTGGCTTCTCATATGGCAGAGATTGGACCGGTTCAACCAAACACGTCATCTGGAAATGGGGCTTGCGTTCTGAAAATGTTTCAG[T/A]AAGCTACCTGTGACCCTATACCCCCCTACCCCACTTCCTCACTTGTCATAATGTGTCATCTTCTTTTCTAGAAGCTAAAGTCTGGTCTCTGTCTCTTTCAGTATCGTGGAGGAGGGTTTGTCTTATCGTTTCCATGCCTCATGGCCGTTTGTGCTGAAGATTCTGGGTTGTTTCTACAGAGCTGCAGGAAAACAGGCTCATCCTATTATGATAAAGGTAGATTGATATTTGGAATTTTATATTAGAGATCCACCAATAGAAAATTACGGCGATCATACGTGTATATTATTGTTTATAGTTTTTCCCCAAACTAAAAATGTCAGTGTGTCAAGTATGTGAAGTATGTACAGGAAATGTAATTGACTTTAACAGTGCATTCCACATTTCAGTGCACTGTATTTTGTTTTTAGATTCCAATTTGACTTATTTAATGAAGTTAACATCAACTAGCATGCGCAAAGCACAACATTTAAATCCTTGTCATATAAAAACTGCTTGTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35526
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000034829 Nonsense 603 1283 16 34
ENSDART00000134343 None None 100 None 5
ENSDART00000145887 None None 276 None 9

The following transcripts of ENSDARG00000022410 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 31579059)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 31225007
GRCz11 13 31355457
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGTTATATAAACTCTTAATCTTTGGTTTATTTCAGCCGATGAACTGGAG[C/T]AGTCAGGGCAGAAGCTCATGGCAAAGGTTTATCAGACGTTACAGATGCAG
Long Flanking Sequence:
TGATATTTAGCTCAGAGATTGTTTGTTTGTGTTTATCAGAGTCTCCAGTCTCTCAGTGACCTGAGGGCCACCCCTCAGTTCCCCTTCACTGGTGAGCTGGATCTGGCTGTTGGTGGTGCGGTGGAAAGCATGGGTCCAGAGGTGGTGCTCAACGCTGTACCCCTCCTCATCACTGGAACAGAGTGTGTTTCTTTTTCAATGCTTTTCAATGTAAAAACCAATTAGTGCTTTAAATGAAAAGGTACAAATATGTTTTGTGTGTGTGTGGTTGCAGTGATGACCTTGAGTTTCCACGCAGTTGGTTGATTCCGGTCATTAGAGATCATGTAAAGAACTCTCAGCTGGCTTACTTCAATTCACACTTTTTCCCGCTGGCAAACAAACTTAAACAGACAGGTCTGTATAAGTCTCGCACTCACACGGTCCCAATGTTCTCTGGCGACAGTGTTGCTGTTATATAAACTCTTAATCTTTGGTTTATTTCAGCCGATGAACTGGAG[C/T]AGTCAGGGCAGAAGCTCATGGCAAAGGTTTATCAGACGTTACAGATGCAGGTATGATGTGTATTTTAAGACTGTAAACACATTGTTTAGACCATAATTGTAAATTTTGTCAAGAAAATGAAATGATCTGATCTAAATAATGACATTATGATATACAGTTTAGTTTATTTATAAAGCACAATAAAACAACAGTTGTTGACTATTGTGCTGGACAAACCTAAAAGCTAGAGGCTGGGATGCACAAGAAAAGAAACCAAAGAGCCACTCTGGTGACATCCTTTTTTATTTACAATCTCTTCACTGCTGCCATACAGTTCTCTTTTTCGCATGTTTTGTTATTCTGACCTGAAGTGACAAGCACGAGCACATGCTTTGTGTCTGAGGTAATTAGTCTGCCGTTATTACTGAAATGTGTATTGCCCATACAAAGTGTAAAGCAGATTGGTTAGTTCTTGCTCCTGGGGCATTCTGAGAGTTCAGATGTTTTTCAACTAGGTGTAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9602
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000034829 Nonsense 613 1283 16 34
ENSDART00000134343 None None 100 None 5
ENSDART00000145887 None None 276 None 9
ENSDART00000034829 Nonsense 613 1283 16 34
ENSDART00000134343 None None 100 None 5
ENSDART00000145887 None None 276 None 9

The following transcripts of ENSDARG00000022410 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 31579027)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 31224975
GRCz11 13 31355425
KASP Assay ID:
2260-6599.1 (used for ordering genotyping assays)
KASP Sequence:
TCAGCYGATGAACTGGAGCAGTCAGGGCAGAAGCTCATGGCAAAGGTTTA[T/A]CAGACGTTACAGATGCAGGTATGATGTGTATTTTAAGACTGTAAACACAT
Long Flanking Sequence:
TTATCAGAGTCTCCAGTCTCTCAGTGACCTGAGGGCCACCCCTCAGTTCCCCTTCACTGGTGAGCTGGATCTGGCTGTTGGTGGTGCGGTGGAAAGCATGGGTCCAGAGGTGGTGCTCAACGCTGTACCCCTCCTCATCACTGGAACAGAGTGTGTTTCTTTTTCAATGCTTTTCAATGTAAAAACCAATTAGTGCTTTAAATGAAAAGGTACAAATATGTTTTGTGTGTGTGTGGTTGCAGTGATGACCTTGAGTTTCCACGCAGTTGGTTGATTCCGGTCATTAGAGATCATGTAAAGAACTCTCAGCTGGCTTACTTCAATTCACACTTTTTCCCGCTGGCAAACAAACTTAAACAGACAGGTCTGTATAAGTCTCGCACTCACACGGTCCCAATGTTCTCTGGCGACAGTGTTGCTGTTATATAAACTCTTAATCTTTGGTTTATTTCAGCCGATGAACTGGAGCAGTCAGGGCAGAAGCTCATGGCAAAGGTTTA[T/A]CAGACGTTACAGATGCAGGTATGATGTGTATTTTAAGACTGTAAACACATTGTTTAGACCATAATTGTAAATTTTGTCAAGAAAATGAAATGATCTGATCTAAATAATGACATTATGATATACAGTTTAGTTTATTTATAAAGCACAATAAAACAACAGTTGTTGACTATTGTGCTGGACAAACCTAAAAGCTAGAGGCTGGGATGCACAAGAAAAGAAACCAAAGAGCCACTCTGGTGACATCCTTTTTTATTTACAATCTCTTCACTGCTGCCATACAGTTCTCTTTTTCGCATGTTTTGTTATTCTGACCTGAAGTGACAAGCACGAGCACATGCTTTGTGTCTGAGGTAATTAGTCTGCCGTTATTACTGAAATGTGTATTGCCCATACAAAGTGTAAAGCAGATTGGTTAGTTCTTGCTCCTGGGGCATTCTGAGAGTTCAGATGTTTTTCAACTAGGTGTACCTGGAAAATGTGTGTTTGTTATGTGCACGTCG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8658
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000034829 Nonsense 613 1283 16 34
ENSDART00000134343 None None 100 None 5
ENSDART00000145887 None None 276 None 9
ENSDART00000034829 Nonsense 613 1283 16 34
ENSDART00000134343 None None 100 None 5
ENSDART00000145887 None None 276 None 9

The following transcripts of ENSDARG00000022410 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 31579027)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 31224975
GRCz11 13 31355425
KASP Assay ID:
2260-6599.1 (used for ordering genotyping assays)
KASP Sequence:
TCAGCYGATGAACTGGAGCAGTCAGGGCAGAAGCTCATGGCAAAGGTTTA[T/A]CAGACGTTACAGATGCAGGTATGATGTGTATTTTAAGACTGTAAACACAT
Long Flanking Sequence:
TTATCAGAGTCTCCAGTCTCTCAGTGACCTGAGGGCCACCCCTCAGTTCCCCTTCACTGGTGAGCTGGATCTGGCTGTTGGTGGTGCGGTGGAAAGCATGGGTCCAGAGGTGGTGCTCAACGCTGTACCCCTCCTCATCACTGGAACAGAGTGTGTTTCTTTTTCAATGCTTTTCAATGTAAAAACCAATTAGTGCTTTAAATGAAAAGGTACAAATATGTTTTGTGTGTGTGTGGTTGCAGTGATGACCTTGAGTTTCCACGCAGTTGGTTGATTCCGGTCATTAGAGATCATGTAAAGAACTCTCAGCTGGCTTACTTCAATTCACACTTTTTCCCGCTGGCAAACAAACTTAAACAGACAGGTCTGTATAAGTCTCGCACTCACACGGTCCCAATGTTCTCTGGCGACAGTGTTGCTGTTATATAAACTCTTAATCTTTGGTTTATTTCAGCCGATGAACTGGAGCAGTCAGGGCAGAAGCTCATGGCAAAGGTTTA[T/A]CAGACGTTACAGATGCAGGTATGATGTGTATTTTAAGACTGTAAACACATTGTTTAGACCATAATTGTAAATTTTGTCAAGAAAATGAAATGATCTGATCTAAATAATGACATTATGATATACAGTTTAGTTTATTTATAAAGCACAATAAAACAACAGTTGTTGACTATTGTGCTGGACAAACCTAAAAGCTAGAGGCTGGGATGCACAAGAAAAGAAACCAAAGAGCCACTCTGGTGACATCCTTTTTTATTTACAATCTCTTCACTGCTGCCATACAGTTCTCTTTTTCGCATGTTTTGTTATTCTGACCTGAAGTGACAAGCACGAGCACATGCTTTGTGTCTGAGGTAATTAGTCTGCCGTTATTACTGAAATGTGTATTGCCCATACAAAGTGTAAAGCAGATTGGTTAGTTCTTGCTCCTGGGGCATTCTGAGAGTTCAGATGTTTTTCAACTAGGTGTACCTGGAAAATGTGTGTTTGTTATGTGCACGTCG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13242
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000034829 Nonsense 735 1283 19 34
ENSDART00000134343 None None 100 None 5
ENSDART00000145887 None None 276 None 9

The following transcripts of ENSDARG00000022410 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 31576142)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 31222090
GRCz11 13 31352540
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AKGTTTGTTCCTGTTGTTTCAGATGGTGTGCACATTTCTTCAAAAAGCAT[T/A]GGAGAGACTCAATGCWGACAACACTGAGTTTACCAGGTAATACAGCTTCA
Long Flanking Sequence:
TCACTTAAATTGCGCGTGAGCAGTGAGGCAAAAATAGACCCAGCACTGAAACTATTGCGGCACTGCTGCTTCTGCAACGCTTGTTTTTTGCGCTGACGCGATGCTTCTGCGTATGATATGAAAGCTCTTATCTGGTAACATGGACGCCAAAAAATATGCTGCTCACACTCTGCTCGCGCTTGTGGTGTAAAATAGGCTTAAGTATCTGCAAGTAAAAAGTTATGTAGTTGCATATTTTTTGCTCGCTTTATGTTAATTACATTTATATACTGCTTATATTGCAAAAAAAAATACTGCATGTTCTTGCCTTCCTGTAGCTCAAACAGAAAAGCCACTAATTGGTTTAATTTCACATGAAAACTTTAAAAACAGTGCAAGTATTTCTTGATTAAAATAATAAATGTCCTGCGGTTTGTGCCGTTGGCTCTTTTCACAATGTCAATACCAAATAGGTTTGTTCCTGTTGTTTCAGATGGTGTGCACATTTCTTCAAAAAGCAT[T/A]GGAGAGACTCAATGCTGACAACACTGAGTTTACCAGGTAATACAGCTTCATACCTTTACAAGGCATTATAGAATACGTTATAGTGTGAACAGAAACCTGATGCATGCATAAAGTGACAAGATAATTTAATGGCCGTGCTGCCTAAAAGATGTGCTTTGTTTTGTTTAAAATTAAATTTTGAGTCTAGCATTTTAATATTAGTGTTTGTTATTTCATAGGCTTGCAGTCATTGACCTGGTTGTAGCCATGGCTCCGTTTGTGGATGAAGCGTCTATGAGCCAGATACTTGAATTCATAAAACCTTTTGTGGAGGTGAGAATCTTCCTAATAAATCTTTTGTTTTCATTTGTTTTGTCATGAGTGCACTTTACATTTGTTTGTGTGTTTATAGAGCAAGGATACTGGCATCCAGAAGAAAGCCTACAGAGTCCTGGAAGAGATCTGTGGAGGAGAGAGAGCGTCCTGTAAGGCTTTTGTTCTGGCAAACCTGGAGCAGCTGA
Associated Phenotype:
Not determined