Busch Lab

ZMP

si:ch211-69k21.4

Ensembl ID:
ENSDARG00000062347
ZFIN ID:
ZDB-GENE-091204-75
Human Orthologue:
MTUS2
Human Description:
microtubule associated tumor suppressor candidate 2 [Source:HGNC Symbol;Acc:20595]
Mouse Orthologue:
Mtus2
Mouse Description:
microtubule associated tumor suppressor candidate 2 Gene [Source:MGI Symbol;Acc:MGI:1915388]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa11453 Nonsense Available for shipment Available now
sa9452 Essential Splice Site Available for shipment Available now
sa9606 Essential Splice Site Available for shipment Available now
sa34904 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa11453
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000090059 Nonsense 282 1303 1 14
ENSDART00000141387 None None 243 None 4
Genomic Location (Zv9):
Chromosome 10 (position 24996076)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 24595428
GRCz11 10 24564880
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACCATAAAAGTGCATAAATTCCCAATGGAAGCGGAGSARAATACTGGATA[T/A]AAATGGATGTCAACTGAGGTGCCRAAAGGTATGGTGAGGGTACAACCTTC
Long Flanking Sequence:
AGGAAGTTGACTTTTGGATCCCCTTGGAAAGACCACAATGAAAACCACAGTGTGGATGGAGATGCAAATGAGAACTCACAGCCCCTTGACCTCAGGACCTCTAGCTCTCGCTCTGGTGCAAACCGAACCCTGAGAGATGGCCGAAGTGGATCTGAAAGCAATGTCTTTTCATCTTCTCTTTCTGCAGTGACCAGCCTCAGTGGAAGTTTAGCCAGTGCCCTGGACACTGCAGGCTGCACACAGCCTCTCTATTCCCAGTTCACCAAGTCTACCTCAGGCAAAGGCAGGAACCAGCAACCAGCTACTACTGAGTCCTTCATCCACTCAGAGAGAAACAGGGATCTTCCCAGGGATTTGGACCAAAACCATAACTCTACTATACTGCCTCAGGAACCACAATATGACCGAAGTAAGCTAATCACTCCAAGTGGTGCATATCCTTCAAATGGAACCATAAAAGTGCATAAATTCCCAATGGAAGCGGAGCAGAATACTGGATA[T/A]AAATGGATGTCAACTGAGGTGCCGAAAGGTATGGTGAGGGTACAACCTTCTTGTCGGCAGCTTGTCCGCCCTCTTTCTACAGAAAAGCGATTAACCTCAGGATATCCCAACAGTGACCAGGCAGACCAACAACAATCCCACTATTCAGAGACCTGTCATGGACATCAACAAGTGCTAGCTTGTACAGAAGTCAACAGTAATCCCAACACAGGCACAGAGATGGTTCACAACCAGACCTTTACCAGAGAAGCCCAACGTATAAAGAGGCAGAGCTCAGCAGATCGTGCCGCAAGTCCCTCCAGCCTTGAAAGAAAGACACACTTCAGCCGCCGGGCCTACAGCAGTCCAAGTAGACCATCCCCTCCTCCATCCCCCAAGACCACAAGGTCTCCTCAAAGGCATCCTTCATCATCACCCATCAAAACTTTACCCTCTCGAGCTCCACAGTTGGGTTATGCTGGGTACACTTCAGGCTTAAGAGCCCCAGTGAAAACAACTAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9452
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000090059 Essential Splice Site 678 1303 2 14
ENSDART00000141387 Essential Splice Site 86 243 1 4
Genomic Location (Zv9):
Chromosome 10 (position 24997400)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 24596752
GRCz11 10 24566204
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACCAATGCAGGCAGTTAACCCAACCACTCAAACTCCTCAGGAAACACAAG[G/A]TAAGATCTATCGCACAGTTCCATTTATATGGCATGTTTTACATCGCTTTC
Long Flanking Sequence:
GGTCTGGGATTAAACCACCCAGCAACACCATGCCTCACAAAATGGCTGGCAGATCGGACAGCTTCTACGGGTCTCTTAACAAGCCTCTATCTGCAGCAGTAAGGAGTGATTTACAATTGAGAAATATTTTGTTATTAATTAAATGCTTTTATATCCATAAATATTAGTTTGTGTGTATTGGGAGAGTTTATATTCTGCAACCTGGGGTCATGTTTTTGTTTTTTAAAATTAGGTGGGACGATCCGCAGTTGGCCTTGGGTCTCCAGTGTCTGCAGCTGAGGACCCATCTGGATCACCTATGGGAGCACAGGATACAGGGAGTCTTTTTCGTTCACCACGGGGCCTAAGACCTCAACTTGGCGTTGGTGCTGTAAACAGGACTCCTTCTGTACTTGCAAAAGGCAGGATGACCTTAACAAGTCACCCAAAGTCACCACTGACCATCAGTCAACCAATGCAGGCAGTTAACCCAACCACTCAAACTCCTCAGGAAACACAAG[G/A]TAAGATCTATCGCACAGTTCCATTTATATGGCATGTTTTACATCGCTTTCCATCAGTAAAGCTATCTCACATAGCACACTAGTGCAGGTTCGGTGTTTAAAAATGGTTTTCAGTGATAGAATCACCAAGGCTTTGTCCTAAAGGCAAAACTGACTCTGGAGTGTTTTGAGATGAGTAGATGTAAACAGAAAGAAGGAAGAGAATGCCATAAGTCTTCGCATCCCTGCCAGTAATGCATTTGTAATTGTAAGAGATAAACTCATCCCAGCCTCTCGTCAGTAGAAAATACACTTTACCTCCTGGCATTTAGTTGAATATAAATAAAGTTCACATTCATCTTGTGCCATGAGGGAGTTCTGTCTGAGCTTAAAAATTCCCTACCATTTCTAAAGCGCACTTTATTTCCAACAACTTTGCCTGTCAAGGTGAAGATATGAGTTATTTCATCTTAAATCCACTACCAACATTGCCATCATCCTCTGTGTTTTTTCTAGAGGGCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9606
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000090059 Essential Splice Site 803 1303 None 14
ENSDART00000141387 Essential Splice Site 211 243 None 4
Genomic Location (Zv9):
Chromosome 10 (position 25036548)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 24635900
GRCz11 10 24605352
KASP Assay ID:
2260-3244.1 (used for ordering genotyping assays)
KASP Sequence:
TTCAGTTAATTCCCACACACTGCCATTAACTSTTGTCTTTCTTTCTCCGM[A/T]GTATCCCGTAAGGAATTCCAGAAGAGTTCGGATGGCTCCCGTTCATCCCA
Long Flanking Sequence:
TAAAAAGTCTATTTTATATCATCATGCACATCAAGGGATATTCATATATATATATATATATATATATATATATATATATATATATATATATATATATATTCTACACTCTTTTTTTTCTATTCACCATGAGCTGACAGACCTGGGATTTGTGAGATGCATGAATTTTTATATATATTAGAACTATATTCTGTACTGTAAGTGTTGGTCCAAAGATGCCTGCGGCCTCTCTGAATGACATATCTTCAAGTCCATGTCAGCCAGACCCTGGCAGCTGCGTTATTTTGAGGTTGGCTGCCTCTTATTGGAATCGATCCACGGACCACTGAGACTATATTATGATCCATGGAAGGGGAGAGCGATACGAGCAGCAGAGTTGGAGAAGGGTTTACTGTTACAAACCCTTTCATAGATTGCTGTACTGTATGTGTCCCTAGAGCGAATATCCTTTAATTCAGTTAATTCCCACACACTGCCATTAACTCTTGTCTTTCTTTCTCCGC[A/T]GTATCCCGTAAGGAATTCCAGAAGAGTTCGGATGGCTCCCGTTCATCCCAGTCATCCCCTAAGAGACTCGCTGTAGTGTCTCCTAAACCACAATCTCCAGGTAAACCAACCAAGACAAAGATCAAGCTAAGATATTGCTTTCGTCCCCCGCTGCTCTATAGAGTACAGTGCTGCCATTAGATGATGCTATTGGATAAATCTCATCTTACGTCTGGCACTGTAACCCTCTCTATTTTCCTTCTCTCTACGCACACACACTTAGAATGAGAGGGTATTTCATATACGATGCAATCAGTTTGGCCACTGGGGCCAAGTTCAGCTGACATGTTGAACAAAATGAAGCAATACTCCTGGTTTAGGGCATCAACGAACCTAATTAGAGCTTAAATTGTCTTGAAGGATTTGAAATGGTTAGTTCACCTTAAAGCTGTAGCCACTTCAGAATGGGAACTAGGTAATAATGTTTTGTTATTTGAGTTGTACTTTTTCATTGGAAATAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34904
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000090059 Nonsense 1059 1303 10 14
ENSDART00000141387 None None 243 None 4
Genomic Location (Zv9):
Chromosome 10 (position 25048142)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 24647494
GRCz11 10 24616946
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGACAGAAATGGGGAGAAGAGCTCAATCTCATTTCGTTTATCTTAGATT[T/A]AAGGAAAGCCCATGAGCAGCAGAAAGCCAGTCTAGAAGAGGACTTCGAGA
Long Flanking Sequence:
GAAAACATGTTAAATGAGAATTTGAAATATTTTATAGCATACTTTAAAAAAAATAAATATGATTTAGTATTCAAAATATTTTAATTTGATAATGTATTTAAATAAATTGCTCTTACACTTACTTTTACACCGTTACTTTTACCGTAAACCGACATGCCAACCATTTGTTAGAAGTTAATATTTTTAAAACGATGGGATGTGTTGGGAAAAAAATGCATTGAGTGTGTTAACTAGCGACATTAGGAGTTAGGAAATGCAATCCAAAAATGTTTTTCTTGGTGGGCCAGCTAAAGGGTTAATGTGGTTTTGTGTGTAGATTGAAGAGTTGACTGCCAACCATGAGGCTGCCCTTGAAGACCTGAAAACCATGCACAACATCACTATGGCAACACTCCAGGAGGAACATGCCAGGACGATGAGAGGTGAGTGTCTGATTCATAACATCACCAACAGACAGAAATGGGGAGAAGAGCTCAATCTCATTTCGTTTATCTTAGATT[T/A]AAGGAAAGCCCATGAGCAGCAGAAAGCCAGTCTAGAAGAGGACTTCGAGAAACTGCGCCTCTCACTTCAGGTGATTTGATTCAAGGTTTGTTATGAAGGTTTTTGCTCTTCATTTGAGGTCATTAGTAACAATAATGTTTTCTTCAGGATCAGGTGGACACTCTGACATTCCAGAACCGGACTCTGAAAGACAAAGCTAAGCGTTTTGAGGAGGCACTGAGGAAGAGCACTGATGAACAAATTGTGGTATGTTTCTTTGAAGTCGTCATGAAAAACTATATTCTATCTATATATTTCTGTAATTTTTGTCCCTAATGTGTGATGCACATCTAAATCAAACAGATTCTTTAATGAGAAAAAATGTTCATCAGGACAAATCAAAATAAAAATGATGGACAAATCAGCTGATTTTGAATTATATAGCTGTTTTGCTATAGGTGAATTTCATTTGAGTGACACATTGCCTCGCACTTACATGTCATTAAAGAAAGGCAGAGATG
Associated Phenotype:
Not determined