ZMP
tbxas1
Ensembl ID:
ZFIN ID:
Description:
thromboxane-A synthase [Source:RefSeq peptide;Acc:NP_991172]
Human Orthologue:
TBXAS1
Human Description:
thromboxane A synthase 1 (platelet) [Source:HGNC Symbol;Acc:11609]
Mouse Orthologue:
Tbxas1
Mouse Description:
thromboxane A synthase 1, platelet Gene [Source:MGI Symbol;Acc:MGI:98497]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa9271 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa36591 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa9271
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000047555 | Essential Splice Site | 65 | 546 | 3 | 16 |
| ENSDART00000109497 | Essential Splice Site | 65 | 546 | 2 | 13 |
| ENSDART00000144246 | Essential Splice Site | 65 | 546 | 3 | 14 |
Genomic Location (Zv9):
Chromosome 18 (position 12153168)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 18 | 12735897 |
| GRCz11 | 18 | 12704615 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AACACCCAAAGCCCTTGCCATTTATTGGGAACCKGATGATGTTCCGAAAC[G/A]TAAGAATTTWGGTTATTTTATGAAGCACAAAAGTCATTCTCTCCTATATG
Long Flanking Sequence:
TTGTTTGTTGTTTCACACTTTAAACGTCCGCTAAATTACTAGTGAGTATAGTCAAAGACTATAGAATACACAAGACATGTCACTCGTATAATTTTGAATGGGGAAAAGTGTAACTGTGAATATGGCAAATGAAACCCCGGCTTTTAGTACAGGAGCCAATCAGCAATCGCTATATACTGACGATATTCTGGGGGAGGGGCTCAGAATAGACGTGAGTTTCTGCTAATTTTGTGTGATTTGAACGTTTATAAACATTGACGCTTCCTGACTTTCACAGTGCATTGTGAGACTTTTTTTTAGAGCGTGAATGTTTAAATACACAATTGATTAAGGCAGCTGAATTCGATGCAATAGTAGTCGTTTACACTAAGCTCAAACTGAACTGATCTTGTGTTTGTGTTAACAGGTACTCTATCTCCCCGTTCTCCAATCTGGAACGATGTGGCATCAAACACCCAAAGCCCTTGCCATTTATTGGGAACCTGATGATGTTCCGAAAC[G/A]TAAGAATTTTGGTTATTTTATGAAGCACAAAAGTCATTCTCTCCTATATGCCATGTACACACACACACTTTTCGTACCGATGTTCTGAAGCAGGAATAATGTAATTTCTCTCCGCGAGACTCACTTCATTAGATGTGTTCATTAAAGATGACTCACCGCTAATGACATCTAATGCCATCTGATTCCCAAACAGATTATCCTCTGTGCTTTTACCAGCACAGTATAAAAGACGGACGGGAGAATGGGTGGCTTTAATATTGCAGAATTAATACTTTTTAATTCCTCATGTATTATCATTTTTCAAAGTTTAATCTTTGTCCTGAGCAATAATGTAGCAAATCAACAGCTGCAGTACTTCAGGAACCCCTCTTTGTTTTATGAGAAATAAAGGTCAAGATTTTGATGCTGTGGGGCAGTTCATGTCCAGTGAGAGTCTTTAGATGTATGAATGTGAAATGCCTGTATTCATCTGGCAACCAGTAAACGTTTTTATTTATTTA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa36591
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000047555 | Nonsense | 80 | 546 | 4 | 16 |
| ENSDART00000109497 | Nonsense | 80 | 546 | 3 | 13 |
| ENSDART00000144246 | Nonsense | 80 | 546 | 4 | 14 |
Genomic Location (Zv9):
Chromosome 18 (position 12174112)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 18 | 12756841 |
| GRCz11 | 18 | 12725559 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGCACAGGGTTTCTTTAAGTCTCAAGCTGACCTCATAAACAAGTACGGA[C/T]GAATTTGTGGGTAAGTCTCTTTTGATTGTACTCACAGTTATCAAACTGTC
Long Flanking Sequence:
CCAATAGAGAGAATTATACTTCAAAATAAAGTGTGACCGAATCAGTAACAATTTAAAATAATGGTCAGTTTACTAACATGACCTAGGACTGAACAATAGTTGTTCTGCATTTAATAATCACAGTTCAACATTTTCTAATGTGTTACTACACTCTAAAGTTAACAGTCTGTGTGAATAAAGTAGAACTAACAATAAACAACTTTATTTTCAGTAACTAACACTAATAAATATTGTAATAAATGAATTGTTCATGTTACAAAATACATGTAATACATGGACCATTACTTTAGGTTTCACCATTAAAGTAATACTTTCAATGCAAAAAGGAATTGGTCATTCAATTTATAATTCTCATGGTTGTGGAATTTAATAGTCTCTAAAATAAAATAAATCACTTGTGTAACTTGAATATCAACTTGTCTTCTAACGTTTTCATAAACTTTCTGCTTTTTGCACAGGGTTTCTTTAAGTCTCAAGCTGACCTCATAAACAAGTACGGA[C/T]GAATTTGTGGGTAAGTCTCTTTTGATTGTACTCACAGTTATCAAACTGTCCATCAAATGCAGAAATATGAAAGAAAACAGATTGAATTGTATTTTGCTTTCTTTGTTAACAATAAAAACTGAAATTGCCGTCTAAAAGAAACCTTTTGTCGAAAGCATTAATAAACACAAATATGCGAAACCTATTTGTTTTGCCAAGTGAAACATGAATGACTTCTCATTACCCCCTGGGTAATAGAAAATGATTTTTTTCCCCCCCTGATTATATTCCTGATGAAAAGTGCCCGACGTGATTGCTTTAGTCATTTCCACATTTATAGAATTACTTTAACACCACAGCGTCTCTGCGTAACACCCATCACACATGAGGCTCTTGTTCACCATCCTGTCATTCATATTCAGACAGCATGAGCCTCTCAGTGAGCGCCCAGTGTCCTCTAATTTAGTCCGTCGCTTGCCAGACATTGTGTTTTAATATGCCTGCTTCTGAGAGGCCGACTT
Associated Phenotype:
Not determined