ZMP
eif4bb
Ensembl ID:
ZFIN ID:
Description:
eukaryotic translation initiation factor 4B [Source:RefSeq peptide;Acc:NP_999883]
Human Orthologue:
EIF4B
Human Description:
eukaryotic translation initiation factor 4B [Source:HGNC Symbol;Acc:3285]
Mouse Orthologue:
Eif4b
Mouse Description:
eukaryotic translation initiation factor 4B Gene [Source:MGI Symbol;Acc:MGI:95304]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa20761 | Nonsense | Available for shipment | Available now |
| sa9211 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa20761
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000021520 | Nonsense | 64 | 569 | 3 | 13 |
| ENSDART00000045775 | Nonsense | 64 | 632 | 3 | 15 |
| ENSDART00000127365 | None | None | 128 | None | 5 |
| ENSDART00000128308 | Nonsense | 64 | 632 | 3 | 15 |
The following transcripts of ENSDARG00000010194 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 6 (position 39006487)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 6 | 39078087 |
| GRCz11 | 6 | 39075623 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTCTTCCTCTATAGTTTCAACTTCCTGGCATACTGTGGAGGACACGTAT[C/T]GAGCTCCTCCCATTGATCGTTCCATCCTGCCAACTGCGCCCCGTGCAGCA
Long Flanking Sequence:
AACAATAACTTGATGCTTATTCACATTAACTGTGTATCCTTGCTTACGAAGCCTCCTTGATCCTCAGTCAGAACTGGTCCATCTGGCAAGACTTTTTAGAACTATTTGCTATTCCATGGGCAAGAGAGCTGCCGTTAAACCTGGTCAGATGGTGGTTTTGAACCATCATGCTTTATTTAATCTAGGTTTTGACACACCATCTATGAAAGTTGCTATTATGTTTATAACATAATTTACATTGGCATCCAAACAGAGCAAATACAAATGTGTCTGAGCAGCATGCTGTAGTTTTTTTATAGACAAGTTAAGCTGCCATTTTAAATGTGGTGCTCAAAACAATTTCTCTTTGTCTTGTTGGCCACATCAACCCCGGAGGCTAAATGTAACTTTAAACAAGATCTGGTGTATTTTGAGATCTTCTCAAAGAAATCCTGTTCTGTGGTGTTTCATTGTCTTCCTCTATAGTTTCAACTTCCTGGCATACTGTGGAGGACACGTAT[C/T]GAGCTCCTCCCATTGATCGTTCCATCCTGCCAACTGCGCCCCGTGCAGCACGAGAGCCAAACGTCGACCGCTCTCGACTGCCCCGCAGCCCGCCTTACACCGCCTTCCTCGGTAACCTGCCCTACGACGTGAGTGAGGAATCCATCCGGGACTTCTTCAGAGGCCTTGCGGTCAGTAAGATCATATGCATCTTTATAAACCAGATGCTTGGACAACATGCATACTTTTTCACAATAGTATTGAAGGGAGTGTTTGCATTAGCACTTGATGGATGCAGAATATGTGTAACTGTATGTGTTTCATATGTGTTTGTGTTTTCAGATCAGTGCAGTACGCTTGCCACGGGAGCCAAATAACCCAGAGAGACTTAAGGGTTTTGGTTATGCTGAATTTGATGATATTGAATCACTTTTGCGTGCTCTCAGTCTAAATGAAGAGGTGGGTGTTTAATCAAATTTAAGCTTAATACATTGATTTTTTTTTTCTGCTTTTTTATTTTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa9211
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000021520 | Essential Splice Site | 327 | 569 | 8 | 13 |
| ENSDART00000045775 | Essential Splice Site | 327 | 632 | 8 | 15 |
| ENSDART00000127365 | None | None | 128 | None | 5 |
| ENSDART00000128308 | Essential Splice Site | 327 | 632 | 8 | 15 |
The following transcripts of ENSDARG00000010194 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 6 (position 39000805)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 6 | 39072405 |
| GRCz11 | 6 | 39069941 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TCGCTTTGGAGATAGRGAGGAMAGGAGGGATGAAGGCAGAGAAGAGAGGG[G/A]TAGATTGAAACACTAAAGATACAACTTAATCAAAAKTGTAGCACGTCTCT
Long Flanking Sequence:
ATTTAGCTTATCAGGATCCTAATGGTGCTGTTTTTGGCAGTCAATGTTTATTATCAGTGACATGCTGTTGTCTCTTTGCAGAGTCGCGTGACCGCTACGAGTCAGACAGGTTCAGAGATGGTCCACGGCGTGATGATCGCTTCAGTGGTAGAGATCGCTACGATGACAGGGATCGAAAAGATCGTTATGATGACAGAGACCGAAGGGATCGCTTCGATGACAGAGGCAGCAGAGACTATGATCGTGGAGGTTGGCTGACACAGTTCACTTTTATTATGTAAAGTCCACCATGAATGCTAGTTAAATTTTTGGTGTACATGCATATTGTAGTTTGCGTTATAACTAATTGTTTGTTCATGTGATTGTGTTAGGTTTTGATTCACGTGGTGGAGGACGTCGGGGATTCAGCAGTGGCTTCAGACGGGACTATGAGGACCGGCGAGATGGAGATCGCTTTGGAGATAGGGAGGACAGGAGGGATGAAGGCAGAGAAGAGAGGG[G/A]TAGATTGAAACACTAAAGATACAACTTAATCAAAAGTGTAGCACGTCTCTATTCTGATTGTCTAATTTTTTTGTTTTAGGTCCTCCACAGAGGCCCAAGTTAAATCTGAAGCCACGGAGCATCCCGAAAGAAGAGGAGCAGAGTGGAAGCGTGTCCCCCCAGAGCAACCCGACAAATACCAGCAGGGCCTCCTCTATATTTGGAGCAGCCAAGCCTGTGGACACAGCTGCTAAAGAAAGAGAGGTGGAGGAGAGGCTGAAGAAAGAACAAGAACGCCTCCAGAGACAACTGGAGGAGGACAAGAACAGGCCCTCAGAGAGACGGCCACGAGACAGGTGAGATGGGCCCAGTAAATGGGGTGATGTGAAACTTGCCTGCTTCATGTCTAGGCCATCATCTTGGAACCTGCACATCAGAATAATTAATCAAACCAGCCAACATGCAAATTTTCACTTAAAGAATGAAAAAAGTGGCTAGGTTAGATTCGTTTAAACTTTGTA
Associated Phenotype:
Not determined