ZMP

arhgef7a

Ensembl ID:

ENSDARG00000006299

ZFIN ID:

ZDB-GENE-060322-11

Description:

Rho guanine nucleotide exchange factor (GEF) 7a [Source:RefSeq peptide;Acc:NP_001116707]

Human Orthologue:

ARHGEF7

Human Description:

Rho guanine nucleotide exchange factor (GEF) 7 [Source:HGNC Symbol;Acc:15607]

Mouse Orthologue:

Arhgef7

Mouse Description:

Rho guanine nucleotide exchange factor (GEF7) Gene [Source:MGI Symbol;Acc:MGI:1860493]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa9534	Essential Splice Site	Available for shipment	Available now
sa8972	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa13978	Essential Splice Site, Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa9534

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000045093	Essential Splice Site	649	861	16	23
ENSDART00000141408	Essential Splice Site	648	858	16	22

The following transcripts of ENSDARG00000006299 do not overlap with this mutation:

Genomic Location (Zv9):

Chromosome 9 (position 22595173)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	9	21750959
GRCz11	9	21561828

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

GCGTCCAGCGCCTCCACTCAGGCCCTCAGCTGCTCTCTGTTATAAAGAGG[T/A]ATTRTAAYTTCCACTTACAAATTTAAAATTAGGTATGCAAATATTATTAT

Long Flanking Sequence:

TTCACAAATAATAATTTGATTCAATTGATTGATTCTCAAAGTGCCAGTAGCCATTGACTTGCATATATGGATCAATCTAAAAATCATCTTAAATGTTGTTCTGGAGAAAAAACCCCCATCTACTTTACATCTTGTATGGCCAAAATTAACAGTAAACTTTCTGGAGAACTATCCCTTCAAGTGTAGGGTAATATATTTAATCCTTCCATTAGTTTGATTCTACTGTAAAATGTGGCCTAATATCATTCACTTAACTGTCAAAATCTTACTTCTCTAGCTCCCGTCTCACCCTCTGACGCCCTCCAGACATGGAGAAAGCCGGGGCCTAACTGTGGCTCCTGCTTACCACACCCTACCACACCCCTCCTCTCATGGGACCCCACATAGCACCATGATGTGGGGTCCACTGGAGCCCCCAAAAACCCAGAAGCCCTGGAGCCTGAGTTGCTTGCGTCCAGCGCCTCCACTCAGGCCCTCAGCTGCTCTCTGTTATAAAGAGG[T/A]ATTGTAACTTCCACTTACAAATTTAAAATTAGGTATGCAAATATTATTATAAAATGTAAAAATTATTACTTTCTAACATTTGCTTTGATATAATAGTCACAATTTTTATACTAATTACACACCTCTTAGGCTAACTAAATAATTTCTACGCTTTTAGAACCCAGTTAAGGTTTTCGTATATATGTTCATTTTTCAGTTATGTTTAAAAAAGTGGACATATGAAAGCTATTGTTTAATGTTAGTAAACATCCTGATTCCACTCAGCCTGCTGATAAAAGTTAACATGATAGCTTGATTTAAGTATTAACCGACAACCTAATAGGTTTTGTAATAGCTGTTTATTTAACCACTGACAAAGGGCTTCCATAACCAATAAATGGCCTGCATGAACAGAAAAAAATGTGTTTCTTTCCAGTTGGATCTCTTTTTCTACATTTCTAAAGTTAAATCAAATTAGAGTATGGGCTGACGTGCTAAAATGTCAATAACTCATCACTTTA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa8972

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > G

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000045093	Essential Splice Site	711	861	19	23
ENSDART00000141408	Essential Splice Site	710	858	19	22

The following transcripts of ENSDARG00000006299 do not overlap with this mutation:

Genomic Location (Zv9):

Chromosome 9 (position 22597189)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	9	21752975
GRCz11	9	21563844

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

TCATTCATATGATTTAAYGCCCCTCTCATCCRTGACCGGACGGCCTCCTC[A/G]GCATGGCAAGGCACTGATCTCATGCACAACCACGTTTTGGATCAGTCCAG

Long Flanking Sequence:

CCGGGCAGGTACTGTAGCTCTAGAGGAGGACGCTCAAATCCTGAAAGTGATCGAGGCCTACTGCACGAGTGCCAAAACCAGACAAACTCTAAACTCAAGTAAGTCCTGTCCAAGGCCCCACACACATCCGTCTCTTTTCCTCTAAAACATTTCTCATTCTTACCTACTTTTCTATATGTTAACATAGAAATCTTGAAACTGAAGTCTTGATCTTAACAAGGTTTTCCTGGATTTCTTATAACAATGTCCTCTCTCTTTTTTCCTCATCATTACTTAATGTTCATTTATCATGACCCCATTCCCCATATTTTCATTACGACATCTTCATGCATCTTTTATTTTTATCTGAAAAACATTTTCATTCTATCTGGTTATTATTGGTTCTTTCATCTATGTGGTCGGCCCCATTTTATTTCCTTCCACCTCCATTTGCAATCCTCCCTTCCCCCTTCATTCATATGATTTAACGCCCCTCTCATCCATGACCGGACGGCCTCCTC[A/G]GCATGGCAAGGCACTGATCTCATGCACAACCACGTTTTGGATCAGTCCAGCGCGGATTCTCTGGGCCGCCGTAGCAGTATCTCGAGGCCCGAGGCCACTTCTGACCTCTCAGAGGACTCTGATTATGACAGTATATGGACGGCCCACAGTTACAGGATGGGCTCTGTTACCCGTAAGAGCTCCTACATCTCCCACCAAAATTAATCTCCCCCTCACTCCTATTTCAAATGACTTGATATTTATTTGAAACTATTTATTTATTTATTTATGTATTTATTCGATGCCCTGTCATGATGCATATTTATTTTGGTCATTTTTATATTTATTTATTTATCTATCTATCAGTGTTGTTTTAATCACACCATATCATTTTCTGCATATATACTGTATGCACTTTCCCAAAGCAGTTCCCTGTTGCCTTGACATCTCAACTCCCCAGAACCACAAACCTCACACAACTTTTTTTTTTACGTTGTTTGCATCGCATACAGTATTTATTT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa13978

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

C > T

Consequence:

Essential Splice Site, Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000045093	Essential Splice Site	828	861	22	23
ENSDART00000141408	Splice Site	819	858	22	22

The following transcripts of ENSDARG00000006299 do not overlap with this mutation:

Genomic Location (Zv9):

Chromosome 9 (position 22599400)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	9	21755186
GRCz11	9	21566055

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

ACATTGATATKTYTGTTTCCTAGTTAACRGATTTTAACCTTTCAACAGGA[C/T]TATAAAAAAATGAAAAAATCCCTGGAGGAAGAACAGAGAGCTCGGAAAGA

Long Flanking Sequence:

GCACAGTGGTCCTGTACTGAGCTAATCGATAAGTCCAACTAAACTAAACTAGCTGAAATCAATTTGCGGGGCTTTTCTTTTGAAACAGGACAGTGGAAAGATGGCAGTCCAGCATTGATAGTTCCTGGCGACGAGAAGTTCAGTGTAGACGAGTTGAAGAGTAACGGTCAGACTCTTCTGGAGGAGAAGTAAGACATATTTATCGTACATATTTGTCCACACTCAGAACAGGCTTTATAATATATGTAAAGAAGATGGTTGTTTGTCAAGGGAACATATTCAAGAGCTTATGCATAAAAAATATTTAATGACATTAAATATTATTTTTTTTCCTTAGGAGTCTTGTTGATGTTGTTTATGCTCTGAGAGATGAAGTACAAGAACTTAAACAGGTGAGTGTTGAGAGGGTTCTATGATGTTTTTAATTGTATATGTGTATTAAAATAGAAAACATTGATATGTCTGTTTCCTAGTTAACAGATTTTAACCTTTCAACAGGA[C/T]TATAAAAAAATGAAAAAATCCCTGGAGGAAGAACAGAGAGCTCGGAAAGATTTGGAGAGGATCGTTAAAAAAATGCTAAAGAATATGAATGATCCTTCTTGGGATGAGACAAATTTATGATATTAGCTGCCCTCTTACTACAGGTTTCTTATTTTAAACTGGATAAATGACCTGGAAGCCCTTATAGGTCATATAAATTTACCTTTATCATGTACATGGGTTAATATGAGTCTGCAGTAGCATAAAAATGTTACGTGTTGAATCTAATACGGCTCTAAAAATTGAAAAACACTAATTTTATTGCTTAACAATCATGATCGCATCAGGCGGCATGAATGTTATCTGTTGAATTTGTCTTCCACCTGATGATAGGTGCTGAGAAGGACAGTTCCTTAGTCAGTTTGGGATCGAGAGTGTCCTGTTTTTCTACAAAATTACCTTTATCACTACAAGAGTTCAAGAGATCATCAGATTTTACAGGTACTTGTGGTTTTTAAATG

Associated Phenotype:

Not determined