ZMP
arhgef7b
Ensembl ID:
ZFIN IDs:
Description:
Rho guanine nucleotide exchange factor (GEF) 7b [Source:RefSeq peptide;Acc:NP_001008624]
Human Orthologue:
ARHGEF7
Human Description:
Rho guanine nucleotide exchange factor (GEF) 7 [Source:HGNC Symbol;Acc:15607]
Mouse Orthologue:
Arhgef7
Mouse Description:
Rho guanine nucleotide exchange factor (GEF7) Gene [Source:MGI Symbol;Acc:MGI:1860493]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa8932 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa18335 | Nonsense | Available for shipment | Available now |
| sa31230 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa8932
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000042086 | Essential Splice Site | None | 643 | None | 21 |
| ENSDART00000108528 | Essential Splice Site | 111 | 799 | None | 21 |
Genomic Location (Zv9):
Chromosome 1 (position 46478094)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 45290347 |
| GRCz11 | 1 | 45982142 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCCACTTAAATGGTGAAGTAAATKWATRTTGATGTGTATTTTTTGATTGT[A/G]GAGTCCGGTGGAGGGAGTAACTCGGTGTGTTCCCGTCAATCGTCTTCTCT
Long Flanking Sequence:
AATTTTAGTGTGACGCCCCGCCATGGAAGAATGATTGTAGCGGAAGCCATGGTAATATTTACGGATGGATGTACTATGAACATAATATACAAGTCATGTTAACTAGAATCAGATATATTTACAAATAGATGAACATACTGTACAAGTTGCTATTACTAATCAGAGATAAGCAAATAGAAATGAACATAACATGCAGGTTGTTATTTGCTATAAATATTATGCGTTTACAAATGTATATGTGCAGTGTAAATGTACATTTAAAAATGGGTAAGTACAGTGTAGTGCAATTATTATGTGCTATATTAAGTGTGAAGTGGTTGGGTTGAGTGTAAGTTATGGGGGTAGTGTAGTGGTGTATGGGGTGGGCCAATAATCACCTTAATCTAGATACTCAATAGTAAAGTTACATTTTAACTGTAAAAAACAACTATTGGGATAAAATGTCATGTCCCCACTTAAATGGTGAAGTAAATGTATGTTGATGTGTATTTTTTGATTGT[A/G]GAGTCCGGTGGAGGGAGTAACTCGGTGTGTTCCCGTCAATCGTCTTCTCTGCGGATCAAGTCTTTCGACTCGCTCAACTGTTCGTCCACTCACAGGAGATCCTCCAGGCACAAGTTCAACCAGTACCGCAGTCTGGTGAGCCTCACAACCACTTTACACACTTATGCCTTGTGTCCACTCCACTGAGTGGTACAGCACGGTACGAAACGGTTCTGTACGGGTCAAGTTTCTCAGGTTTGTGTCATGGAATCAATGGTACGGTTTTTGTAGGCGCGGTGTATGACAGAAAGATGCATTCGAAGTTACTTAATTGAAGTTTGCATATTGTATGAGAAGCACTTCTTACTAAACAAATGCTTTATATACATAAATACTTGAGTATAAATGTTCATTACTAACCTTTCTATGAATATGATTTGATGAATACTGCAGATCAACGATGTGCGAAATAGGTTACTGTAGTGTCCGCAATTAAATAAAAAAAATTAAAAATCAAACAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa18335
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000042086 | Nonsense | 119 | 643 | 7 | 21 |
| ENSDART00000108528 | Nonsense | 275 | 799 | 7 | 21 |
Genomic Location (Zv9):
Chromosome 1 (position 46498097)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 45309858 |
| GRCz11 | 1 | 46001435 |
KASP Assay ID:
2259-0987.1 (used for ordering genotyping assays)
KASP Sequence:
CAAACKGAGACTGAATATTGTAAAGAGCTCCAGAACCTCCTCTCCGTGTA[T/A]CYGAGAGCATTACARCCCACCGACAGGTAAGAAAACAAGCTCGCAATTCA
Long Flanking Sequence:
ATATATGAGAGAAATGCTTTATCAAATAAGGTGGATCTAATTGTATTTGCATTGTAAACATTAAATACAAGTTAAAAATGTATTACTTTTTTTTCATATATTAAGGTTTTAGTTATGATACTCATTCTGCATAAATCCGCAGATTTTTACCAAAATTCTGCACAGAAATAGCAAAAGATGTCAGCAGATTCCGTCTGGCCCTACTTATTAATTAGACTCATCAGAAAATCATCAAATAGAGCTAATCTTGTGAAAGATGTGTAAAATTGTGTATTCATATTACAAAATTTATCGCAGAAAAAATCAAATATGGCAGTATCAGATTTTTCCAATATCGTGCAGACCCTACTATTGAATGCTAATCAAACTCAAAAGTTATTAGTTGTTGTAGATCATTAACTGTTGTTTATTTCATTTATTAAATACACACAGGTGGTTCAGAATATTCTACAAACTGAGACTGAATATTGTAAAGAGCTCCAGAACCTCCTCTCCGTGTA[T/A]CTGAGAGCATTACAGCCCACCGACAGGTAAGAAAACAAGCTCGCAATTCAACATACCCCGAGGGCTGATGCTTGTGCGCTTCTCAGTCCGTCTGTCTGTTGTTTTTTAGGCTCAGCGTGTCAGATATCAGTCACATCATGGGAAATCTAGAGGAGATCAGCTCTTTTCAGCAGACACTGGTACATTCACTCGAGGAAAACGTCAAGTAAGCGCCCTCGTCTTGTTCTCGCATCAACAGCGACATCTACTGGCGGTTATTGATAATGAATTGTGTTGTATGTGGATGGCACTAACATTTAAAGTATAGTATTTTTTAACGCTACTACACCGTTTTAAATGCTTTAAATTTTTTATTTGCATCAAATTAGCTTTTCTAGTGATCTCAACGTACACCAATCAAACTGGCTTAAAATACTGAGAGATTTGTGAAGGTGTAATCATAATGTTGAGCACTGTACATACACGATACACAGATGTACATGTAAACATCTCTAGTATTG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa31230
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000042086 | Nonsense | 227 | 643 | 10 | 21 |
| ENSDART00000108528 | Nonsense | 383 | 799 | 10 | 21 |
Genomic Location (Zv9):
Chromosome 1 (position 46501537)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 45313298 |
| GRCz11 | 1 | 46004875 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTAAAGGAGCAAACACACCTGGAATCCTCACACTCACCACAGGCCTGAGC[A/T]AACCCTTCCTGAGGCTGGAGAAATACCCCACACTGCTGAAGGAGATGGAG
Long Flanking Sequence:
TCGGCTAGAATAAAAGCAGCTTTTAATTTTCAAAAATCCTTTTAAGGTCAGTATTGTTAGCCCCTTTAAGCAGTATTTATTTTCGATTGTCCAGAGCAAACCATCATTTTACAATAACTTGCCTAATTACTTTAACCTGCCTGATTAACCTAGTTAAGCCTTTAAATGTCACTTTAAGCTGAACACTAATATTTTGAAAGATATGTAGTAATATAATATGTACTGTCATCATGGCAAAGATGAAAGAAATCAGCTATTAGAAATTAGTTATTAAAACTGTCATAGAAATGTTGTGGAAAATTGTGTTCTTTCTGTTAAACAAAACTTGGGGAAAAATATACAGGGGGGGTAATAATTCTGACTTCAACTGTATATAGAGCTGATTTAAATCATTGCTGTTTGCCTGCATGATTGCATGTTTCAGTGAGGAATTAGGAGAGTTCATGGAAAGTAAAGGAGCAAACACACCTGGAATCCTCACACTCACCACAGGCCTGAGC[A/T]AACCCTTCCTGAGGCTGGAGAAATACCCCACACTGCTGAAGGAGATGGAGCGCCACATGGAGGTACTGAAGCCTCTCACAGACTGCTTTTGTACTGTATGTTGTTGAAGGACACTCGTGTAGTCTGGCACACCTTGACAAGTCAAGATTTTATCAAGACGGAATCGCATAATCTGGCATAGTGACTTTAGTAACCGTCAATAAAAATCGTGGGATCTGACCAGGTAATTATTTGGCCGTAATCATTTGATCATGATGCAATAAAACAGTAATATTGTAAAATATTATTGCAGTTGAAAATAATTATTTTGTTTTTAAAAATATATTTCAAAATCAAATGTATTCCTATGAAGTCAAAGCTGAATTTTCAGCATCATTGCCTCCAGACATTGCCACATCAAAAAAACATTTGTTAGTGTTGATGTTAAAAACAGTCATGCTTTTCATTTATTTGCTTAATCATTTGTATTGACTTTAATACAAATTTTATGATTTTTTTAT
Associated Phenotype:
Not determined