Busch Lab

ZMP

thumpd3

Ensembl ID:
ENSDARG00000059634
ZFIN ID:
ZDB-GENE-030131-9745
Description:
THUMP domain-containing protein 3 [Source:RefSeq peptide;Acc:NP_001082863]
Human Orthologue:
THUMPD3
Human Description:
THUMP domain containing 3 [Source:HGNC Symbol;Acc:24493]
Mouse Orthologue:
Thumpd3
Mouse Description:
THUMP domain containing 3 Gene [Source:MGI Symbol;Acc:MGI:1277973]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa40689 Nonsense Mutation detected in F1 DNA Not yet available
sa8793 Nonsense Mutation detected in F1 DNA Not yet available
sa8825 Nonsense Mutation detected in F1 DNA Not yet available
sa1193 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa40689
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083070 Nonsense 234 477 5 11
ENSDART00000135959 Nonsense 239 482 5 10
ENSDART00000136271 None None 152 None 4
ENSDART00000143378 None None 236 None 4
ENSDART00000146307 None None 193 None 4
ENSDART00000147507 Nonsense 239 271 5 5

The following transcripts of ENSDARG00000059634 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 23684104)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 19939550
GRCz11 6 21999772
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTAACAGGAGGGCTAATAATTCAGTTTTTCTCTTATTTACTAGGTGCTGT[T/G]AAATATCCACAATAATGAAGTTGTGGTTGGCATTGCGCTTACCGTGGAGA
Long Flanking Sequence:
TCAGAGCGCAATTAATATTGGGATGTTCGAGGCGGCAAAGGATCTACTGTTTGTGTCCTTCATTATCTGGAAAACGAAGGACACATTTTGTGGCTGCATTAGAAGAAGCCTTCAAATTTTTTTTAAATGAGACGGCCTTTCGATGACGCAGTGCCCTTGGAATGCATTCTGCGGAGGATGCAGCCTCTGAAATGAGACACAGCTAAACACTTGCCTAATTACGATAACTTGCCTAGTTAATCTAATTAACCTTGTGCCTTTAAATTGCACTTTAAGCTGAATACTAATATCTTAGGAAATATGTTGTCAAATATTATTTACTGTCATCATGGCAAAGATAAAAGAAAACAGTTTTTAGAAATTAGTTATTAAAACTATTATGTTTAGAAAGAGGTAAAAAATTCTTCTCTCTGTTTAACAATTTTGGGGAATATATAAAAGAACTCAAATTTAACAGGAGGGCTAATAATTCAGTTTTTCTCTTATTTACTAGGTGCTGT[T/G]AAATATCCACAATAATGAAGTTGTGGTTGGCATTGCGCTTACCGTGGAGAGTCTGCATAGGAGAAACATCACTCACTTCGGTCCCACAACTCTGCGCTCTACACTGGCTTATGGCATGCTTAGGTCAGTGATATTCCTGTAAAGCATCACACCATCAACAGCCAGACAGAACATTTTATTGACAAATGTTTCATTTAGTTACAATTGTTGTATTAAGGCAATTTAAGAATATTAAGAGGGAAGTATTACAATAAAAACTTATTTAAACTCAACATACAAAATTATTGATAAAAAAATATGGGTTTTACTAATGCAAAAATACATCACAGACAAGCAAAAACACTCATGCCATTATGGTATACACTGGAAGCATACATCTAGTGCAGTAAAAATTGATTGGCTGTTTTTGTATTTCCTTAGCAGCCAATCTCCAGCATATTTTGGAATAAGAAGATTTCTTTGTATTAGCAAATATTAAACTTTTACTATCTAAGCAAAGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8793
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083070 Nonsense 333 477 7 11
ENSDART00000135959 Nonsense 338 482 7 10
ENSDART00000136271 None None 152 None 4
ENSDART00000143378 None None 236 None 4
ENSDART00000146307 None None 193 None 4
ENSDART00000147507 None None 271 None 5
ENSDART00000083070 Nonsense 333 477 7 11
ENSDART00000135959 Nonsense 338 482 7 10
ENSDART00000136271 None None 152 None 4
ENSDART00000143378 None None 236 None 4
ENSDART00000146307 None None 193 None 4
ENSDART00000147507 None None 271 None 5

The following transcripts of ENSDARG00000059634 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 23686375)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 19941821
GRCz11 6 22002043
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CAGCAGTCAGCCGATCAGTCAAYAATATCAAGCACATTCTGAAGAAAACA[C/T]AGGATGGAGGAAGGTGAGGCTTTTGATCGTSTCCTGTAAACYTTTTGGAA
Long Flanking Sequence:
TTTGCATGTAGTCCTCTGTCATTATAAACAGAAACTAAAGTGTTAAACATATACTTTTGGAATGGCCTATTTTAAATGTAATCAGACAACGATTTTTGTCTGGAGAGTCTTTAAAGGAAATATTTTTTTTAAATAAATTCAAAAACTACAATTTTTATCAAAGTAAACAGTAAACCTTAAAAACATAAGATTTTATCTAATGTATTTTAGCTTATGTAGTGCTGTTGATATCTGTTTGTCATTATAGTTTTTTATTGTAGAAAAGTGAGATTTATAAAATGTAAATTTGATCTGGTTTTGCCATGAGAGAAGCTGATGTGCCAATAAATTCAAAACTCTCTTTTCCTTCTGTCATTATACTTCTGTGTCTGAAATATTATCAAAAATCTTTGTTTTAGGGAGCTATGGAATGGCAGAATTCATTCTTTATAGCTGGAGACAACAACGGCACAGCAGTCAGCCGATCAGTCAACAATATCAAGCACATTCTGAAGAAAACA[C/T]AGGATGGAGGAAGGTGAGGCTTTTGATCGTGTCCTGTAAACTTTTTGGAATCATTTTGTAAGTGTTGTTTTAGTATTATTCTAATTAATTTGAAATTTTTTAACTTAAATAGTTTGATATTTTCATTAGTGCTTTTTGTATATGTCCTTAGCGTTCAGTAAATTTAGTAGATCTATGTCATTTTTGGCCCAGTTAAATGTAAAGGCAACATTTACTTTGTTTTTCTATCTCCTTTTGCATAATACATGGGTACATTATATTTTTGTGCGTAGTATATGTCCAAAATTTCATGGTGTGAGTTTTTTTTTTTCATGGTAACAATATATATTACTGGTCACCTTATTAGATGCATCTTACTTTTGCCTTCAGAACTGTCCTAATACTTTGTGGCATAGATTCAACAAGGTACTAGAAATATTCCTCAGATTTTGGTCCACATTAACATGATAGCATCACACAGTCGCTGCAGATTTGTTGGCTGCACATCCATAATGCGAATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8825
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083070 Nonsense 333 477 7 11
ENSDART00000135959 Nonsense 338 482 7 10
ENSDART00000136271 None None 152 None 4
ENSDART00000143378 None None 236 None 4
ENSDART00000146307 None None 193 None 4
ENSDART00000147507 None None 271 None 5
ENSDART00000083070 Nonsense 333 477 7 11
ENSDART00000135959 Nonsense 338 482 7 10
ENSDART00000136271 None None 152 None 4
ENSDART00000143378 None None 236 None 4
ENSDART00000146307 None None 193 None 4
ENSDART00000147507 None None 271 None 5

The following transcripts of ENSDARG00000059634 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 23686375)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 19941821
GRCz11 6 22002043
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CAGCAGTCAGCCGATCAGTCAAYAATATCAAGCACATTCTGAAGAAAACA[C/T]AGGATGGAGGAAGGTGAGGCTTTTGATCGTSTCCTGTAAACYTTTTGGAA
Long Flanking Sequence:
TTTGCATGTAGTCCTCTGTCATTATAAACAGAAACTAAAGTGTTAAACATATACTTTTGGAATGGCCTATTTTAAATGTAATCAGACAACGATTTTTGTCTGGAGAGTCTTTAAAGGAAATATTTTTTTTAAATAAATTCAAAAACTACAATTTTTATCAAAGTAAACAGTAAACCTTAAAAACATAAGATTTTATCTAATGTATTTTAGCTTATGTAGTGCTGTTGATATCTGTTTGTCATTATAGTTTTTTATTGTAGAAAAGTGAGATTTATAAAATGTAAATTTGATCTGGTTTTGCCATGAGAGAAGCTGATGTGCCAATAAATTCAAAACTCTCTTTTCCTTCTGTCATTATACTTCTGTGTCTGAAATATTATCAAAAATCTTTGTTTTAGGGAGCTATGGAATGGCAGAATTCATTCTTTATAGCTGGAGACAACAACGGCACAGCAGTCAGCCGATCAGTCAACAATATCAAGCACATTCTGAAGAAAACA[C/T]AGGATGGAGGAAGGTGAGGCTTTTGATCGTGTCCTGTAAACTTTTTGGAATCATTTTGTAAGTGTTGTTTTAGTATTATTCTAATTAATTTGAAATTTTTTAACTTAAATAGTTTGATATTTTCATTAGTGCTTTTTGTATATGTCCTTAGCGTTCAGTAAATTTAGTAGATCTATGTCATTTTTGGCCCAGTTAAATGTAAAGGCAACATTTACTTTGTTTTTCTATCTCCTTTTGCATAATACATGGGTACATTATATTTTTGTGCGTAGTATATGTCCAAAATTTCATGGTGTGAGTTTTTTTTTTTCATGGTAACAATATATATTACTGGTCACCTTATTAGATGCATCTTACTTTTGCCTTCAGAACTGTCCTAATACTTTGTGGCATAGATTCAACAAGGTACTAGAAATATTCCTCAGATTTTGGTCCACATTAACATGATAGCATCACACAGTCGCTGCAGATTTGTTGGCTGCACATCCATAATGCGAATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1193
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083070 Nonsense 347 477 8 11
ENSDART00000135959 Nonsense 352 482 8 10
ENSDART00000136271 None None 152 None 4
ENSDART00000143378 None None 236 None 4
ENSDART00000146307 None None 193 None 4
ENSDART00000147507 None None 271 None 5

The following transcripts of ENSDARG00000059634 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 23689053)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 19944499
GRCz11 6 22004721
KASP Assay ID:
554-1102.1 (used for ordering genotyping assays)
KASP Sequence:
ATGTCTTATTTTCTATTTATAGCCCCTCGGGCTTGCCCTTAGACATTGTG[C/T]AGTGGGACTTGTGCAATTTGCCCATGAGAAGCAGTTCAGTGGACATCATC
Long Flanking Sequence:
ATCTGCCTCAAGATTCGACGAGTTGTGCATTCAGAGATGCTCCTCTGCATACCTGGATTGTAACGAGTGGTTATTTGAGTTACTGTTGCCTTTTTATCAGCTCGAACCAGTCTGGCCATTCTTTTATGGCATCAACAAAGTATTTGCCTAATAAACGACATGACCATCACATTAGTATGATGTACCTAGTGTACCTAATAAAGTGGCCAGTGAGTGTTTATATTTCATTAGATACTTATTTAAATGGGTAGGTATTCTGTAAGAATGAACAAAAAGGATTTCATAAAAGAAATAAACTTAAATACTGAAAAAGACAATACCTTTTTTTGCTTTTATTTTTTATTACTTTTTATATCTTTTTATTACTTAAATCCTTTTATTTAATAACAATTATTCTGATAGACCCAAATTTTATTGTGTCACAATGAAAAAAAAGTTGAAGTGCTTGCTATGTCTTATTTTCTATTTATAGCCCCTCGGGCTTGCCCTTAGACATTGTG[C/T]AGTGGGACTTGTGCAATTTGCCCATGAGAAGCAGTTCAGTGGACATCATCATCACTGACATGCCTTTTGGAAAGAGGTACTGACAGACTTAAGTAGCTGTAAAACAATTGTACAATAATTATGTATAGTATAAAACATTGCAGGTCATCGGAATGCTCATAATAACCGATTCACCAATAACTGAAAGAGTGCGTTTTAACCGCTTAATGGTATCAGTTAAGTAATTAAAAAATATTAGTTAATATTTTAATTGGCTGCATAAATGTGCAACACATATATATTAAATCACAACATACTACATACATATTTTGCTGAAGAAGCCAAATGAAAGTAGAATTTTGCTGGTCACAGTTTGACAGACGAGTTGATGCCAAACAGTGCTGATGTTGATTGCCTCTGCTTCGGAAACAAGCCGGCCCCAATTCGGAGAGTCTGGATTATCTCTCCATCAGAGCACACTCCGGCATTGCTCATAAGCACAACAAATAGGCTATATTTGT
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037
whole organism
ZFA:0001094
quality
PATO:0000001
normal
PATO:0000461