ZMP
si:dkey-229d2.2
Ensembl ID:
ZFIN ID:
Description:
Novel protein similar to vertebrate transmembrane channel family [Source:UniProtKB/TrEMBL;Acc:A2BFV4
Human Orthologue:
TMC2
Human Description:
transmembrane channel-like 2 [Source:HGNC Symbol;Acc:16527]
Mouse Orthologue:
Tmc2
Mouse Description:
transmembrane channel-like gene family 2 Gene [Source:MGI Symbol;Acc:MGI:2151017]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa8817 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa38469 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa8817
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000044471 | Nonsense | 147 | 865 | 4 | 19 |
| ENSDART00000141924 | Nonsense | 67 | 786 | 2 | 17 |
Genomic Location (Zv9):
Chromosome 5 (position 27281300)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 25036598 |
| GRCz11 | 5 | 25636751 |
KASP Assay ID:
2259-5813.1 (used for ordering genotyping assays)
KASP Sequence:
AAAGAGAAGCACAGGAGTTTGTGGAGAAGTTTGAAGGAGCTTTRRGCAAA[G/T]GAAAAGGGAGGAGACTGTATGCATTTAAAGTCATGATGACCAAGGTACAA
Long Flanking Sequence:
ATACTTGTCCCGGTGTTGTTTCTTGTGCTTACTGTCAAATGCTGAACGATCATGCTGCGTAATGGAAGCAGCCCACATTGGTAAGTCAGTGGACTGGTACGTCAGTTGGTTAGCAAATGTGCGATGATATCACACTTAAACTTAAATACTTGTGCCATGCTGAAATATGGGTCACACTTTATCTTAATGGTCCATTTCTTGAATTTAAGTTACATTGCAACTAATTCTCATTAGATTATACATAGACTGTTATAGGTTGGGGTTAGTGTAAGTTGACATGTACTTGCAAATTTTCTTATATTTAGTGAAATGTTTTATGTTGGAGCAATATTAACAGATATTAAGCAGACAGTCTACCAATACTCAAATGGACCATCAAAATAAAATGTCACCAAGTTATGAAATCATTTAAAGTCACTCTGCTAACACATGTTTCTGTATCTCCATTGTAAAGAGAAGCACAGGAGTTTGTGGAGAAGTTTGAAGGAGCTTTAGGCAAA[G/T]GAAAAGGGAGGAGACTGTATGCATTTAAAGTCATGATGACCAAGGTACAACATTATGTTCACTGTTTAAGTTTCTTCCTAACGGCAATAACTGAACATTTGTGTTGTCTTTGCTTCTCAGAAATTAATCAAATTCAATAGAGACTTTGAAAACTTCAAGACGGCTTGCATTCCCTGGGAGAGTCGAATAAAAGAAGTAGAAAGTCTGTTCATCTCTGTGTTTCCCCCCTGATGTTTCTGTATTTTATATTATTTTCTCATCAGTGTCATCTGTTTCTTGTAGGCCATTTTGGATCATCTGTTGCCTCCTATTTTATTTTCTTGAGATGGATGTATGGACTAAACCTTGTTCTCTTCGGCTTCATGTTTGGACTTGTTGTTATTCCAGAGGTGAGATGTGATACTGTTATCAAAATATTTGTTTATAGAGAATGGGAATGTATGTTGTGTTGTGTGCATTATGTGTATTGTAATGTTAACCCAATCTGTGTTGTTTTCTTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa38469
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000044471 | Essential Splice Site | 354 | 865 | 9 | 19 |
| ENSDART00000141924 | Essential Splice Site | 274 | 786 | 7 | 17 |
Genomic Location (Zv9):
Chromosome 5 (position 27280228)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 25035526 |
| GRCz11 | 5 | 25635679 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACCCAGAGACAGCCGACAACAAGTTTGCCTCCACCACCACAAGCTTCAAG[G/A]TTAATAGCGATGATGAAAGAAAATGTGAAGATAAACTGATCAAATCAAAC
Long Flanking Sequence:
CCATGGACTTCTCTGTGCTATTTGAGTTTGGAGTAAGAGTTTTTTACTAGCAGATTCTTTGTATAACAAGCTGTAAGTTTCCCCTCATTATACCTTTGACATTTTTTACAGGGTTATTGCAAGTACTCCATTCTGTTTTATGGTTTCTACAACAACCAACGAACTATTGGATTCCTGCAGTTCCGGTTACCTCTGTCATACCTTCTGGTTGGTGTTGGGATATTTGGCTATAGTCTAATGGTGGTTATCAGAACGTGAGTTTTCTGATCAGAGCTTTATGTAAACTTGCAAGGGGGTTTACTTTACTTGCTGAGAGTGCAGAATTTACTTCCTAATCATCTGCATATTTTAGAATGGCCAGAAACGCCAATGAAGGAGGAGATGGAGGAGATGAAGGTAACTTCACCTTTTGCTGGAAGCTGTTCACTAGCTGGGATTACCTTATAGGAAACCCAGAGACAGCCGACAACAAGTTTGCCTCCACCACCACAAGCTTCAAG[G/A]TTAATAGCGATGATGAAAGAAAATGTGAAGATAAACTGATCAAATCAAACTTTTAACTGGGTTTTGTTTTCACAGGAATCTATAGTGGATGAGCAGGAAAATCTAAAGGATGAGAACATTCACCTGCGCCGCTTTCTCCGTCTCTTGGCCAATGTTCTCATCCTATGCTGCTTGGCTGGCAGTGGATACCTCATCTACGCTGTGGTCAAAAGATCACAAGACTTTGCCAAGAGGGACAGAAATGAATTGACATGGCTTCAGAAAAATGAGGTACCCCCCTTGTTTTCTCTTTTCATCCGTGTTTTAATGTAATGGCATGACTTGTGAAAATCTGCTCGATCTTTCTTTGGTCAGGTTGAAATTGTGATGTCGCTGCTGGGCTTGGTGTGTCCACCTTTGTTTGAGGCTATAGCTGAGCTTGAAGACTATCACCCTCGAATCGCACTAAAGTGGCAGCTGGGCAGAATCTTTGCCCTCTTTCTGGGCAACTTGTACACTTT
Associated Phenotype:
Not determined