ZMP

LOC796269

Ensembl ID:

ENSDARG00000076294

Human Orthologue:

KLB

Human Description:

klotho beta [Source:HGNC Symbol;Acc:15527]

Mouse Orthologue:

Klb

Mouse Description:

klotho beta Gene [Source:MGI Symbol;Acc:MGI:1932466]

Alleles

There are 4 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa5869	Nonsense	Mutation detected in F1 DNA	Not yet available
sa8655	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa5869

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > G

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000110511	Nonsense	14	750	2	7

Genomic Location (Zv9):

Chromosome 14 (position 742159)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	14	724990
GRCz11	14	743372

KASP Assay ID:

554-3772.1 (used for ordering genotyping assays)

KASP Sequence:

TTTTCTCSCTCTCTGTCTCCTCAGGCTCATGCTAAGGCGTATYACGTCTA[T/G]GATAAACTCTTCAGAGCTCRTCAGAATGGTAAAGTGTCCATCAGTCTGGG

Long Flanking Sequence:

CAGGATATAATCGTCGCTGACTAGACTTTCAAAAGGACTAACTAGTCTCTAACTAGTTTTCTACAGGACATAACTAGTCTCACTATTTTCCTACAGGACATAACTAGTTACTCACATGACATAACTAGCCTCTCTAGTTTCGAACAGAACATAGCTAGTCTCAAACTTGTCTTTTCACAGTTTTCTCCAGCTACACTTTTTTTTTTGTACTTTTTTGTACAGTTGTCTCCAACAGGACAAACATAAGTCTTTCACTAGACTTTCAAATGACATAACTAGTCTCTAACTAGTCTCTTACATGACATAACTAGTCTCTCACTATTCACAGGACATAGCTAGTTTCTCACAGATCGTTACTAGTCTCCCACACACAAGACATAACTAGTCTTTTACTAGTCGTGTACAGGCCATAACTAGTCTCTCACTAGTCTCTCATACACATATATGACTTTTTCTCGCTCTCTGTCTCCTCAGGCTCATGCTAAGGCGTATCACGTCTA[T/G]GATAAACTCTTCAGAGCTCGTCAGAATGGTAAAGTGTCCATCAGTCTGGGCTCTCACTGGGTGGAGCCTCTTCACGGCCAGGCCACGCCCACCAACCTGGAGCTCTGCCAGAAGTCCATGGAGGCCGTGATTGGCTGGTTCGCAGAGCCCATATATGGCAGTGGAGATTATCCAGAATCCCTGAAGTCTGCAAACCGAGGTGTGATCCCAGAGTTCAGTGCGGCGGAGCGGCTCTGGGTGAGGGGGAGCGCAGATTTCTTCTCGGTGGCGTTCGGGCCGGAGACGCTGCGTGTGAGCCGGGGACTGGCACGATTCGGCCAGACGGTGGCGCTGGAGCTCAGGAGTGTGCTGGTGTGGGTTCAGCAGGCGTATGGGGACCCATTGGTGCTGGTGGCCGAGAGCGGGTGGTTCTCTGATGCTTCTGTCGGGGTCGAGGACACACTCGCCATCTACCTCAACAAGAGATTCATCTTACAGGTCATGCAAGGTGTGTGTGTGTG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa8655

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000110511	Nonsense	456	750	4	7

Genomic Location (Zv9):

Chromosome 14 (position 745865)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	14	728696
GRCz11	14	747078

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

GTAGTCGCACGACATCTGYTGCTGGCGCATGCGAAAGCCTGGCGTGCTTA[T/A]GATGTGTATTTTCGCAAACAGCAGGGGGCGACGGTGAGTTTGGCGCTTCA

Long Flanking Sequence:

GACGGATCTTTAAAGCCGGTAAACGGGATCATCCTGCACACGCGGCCGGCTCAGTGCACTGACTTCCTCTTCATCCAGCGGCATCTGTTTCTGCTGGGGGTCACGGGGTCAACACACTACCGCTTCTCCCTAGACTGGACTCAGCTATCGCCCTCTGCTGGACACCCGGAGACACTGCGCTTCTACAGGTGCGTGTTCAGCGAGCTCCAGCGGAGAGGGATCCAGCCAGTCGTGACTCTTTATCACCCCAGCTACAGGTCTTCATCTCTGGGTTTACCTGAAGCGCTGCATGCTAACGGCGGATGGAGGAACGCTAGCACTGTCGATGCATTCGTGCGCTACGCTACATTCTGCTACCGAGAGTTCGGTGCACTGGTGCATATGTGGATTACTATTAATGAGCCCAATCGATTAACGGATGCGTATAGCGGAAGTGCAGATGATAGACGAGTAGTCGCACGACATCTGCTGCTGGCGCATGCGAAAGCCTGGCGTGCTTA[T/A]GATGTGTATTTTCGCAAACAGCAGGGGGCGACGGTGAGTTTGGCGCTTCACGCTGATTGGGTTGAACCGGCGAACCCGTTTTTGGAGTCACACAAAAATGCGCAGCAGCATTTCTTATTGTTTGAACTGGGACGATTCATAGATCCACTATATAACCAAGAGAGCTCCTCGTCTACTCTGATTGGCTGGAGTGACGATGAGAGGGAGGAGCTTAGAGGAGCGCTGGACTTCATCGCTCTGAATCACTTCACTACGCGTTTGGTTTCACCGTGGGCTCACCTGAAAGCATCAACGCCAGATCATGGGTGTTCGCTGATGAACGATGTCAACTGGCAGACCTCGCAGATGGGGCAGGCGCTGGTACCCTGGGGGCTCCGCAGGATGCTGGGATGGGTGAAGAATCGCTATGGCAACCGCCTCCCCATCATTATCACTGCATCAGGAGTGGATGATCAGGCGGCCTATCATGACCAGCTGAGACAGAGTTATATCAGAGACTA

Associated Phenotype:

Not determined