ZMP
si:rp71-1p14.10
Ensembl ID:
ZFIN ID:
Description:
Rho GTPase-activating protein 42 [Source:UniProtKB/Swiss-Prot;Acc:Q6ZM89]
Human Orthologue:
ARHGAP42
Human Description:
Rho GTPase activating protein 42 [Source:HGNC Symbol;Acc:26545]
Mouse Orthologue:
Arhgap42
Mouse Description:
Rho GTPase activating protein 42 Gene [Source:MGI Symbol;Acc:MGI:1918794]
Alleles
There are 7 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa23928 | Essential Splice Site | Available for shipment | Available now |
| sa8901 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa8645 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa29585 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa29586 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa23928
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000079145 | Essential Splice Site | 128 | 805 | 4 | 21 |
Genomic Location (Zv9):
Chromosome 21 (position 21877494)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 21 | 22725907 |
| GRCz11 | 21 | 22762512 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GATCACACCGCTGGAGAAGTTTCGCAAAGAGCAGATCGGAGCGGCCAAAG[T/C]AAGTTCTTAGAGGCCCATTGTGAGTTAATGTTGTACGTGTCAGCGGAAAG
Long Flanking Sequence:
TCAAGTTTTTTTTCAAGTTTTTTTTTTTTGTATAAAGTAACAGTTGTGGTTTTAAAATGTGTGTACTTGTGTAGTTTTTTTTTATTTCAGATGATTTAAGGAATCATTATTTTGGTAGAATTATTTGCTCATTTTAACTCCATAATAATGATTTGATACCATAAGTTGATACCATATACATCCAGTATATTCAAGGAAACTGTGAATGTTCAAGTGTTTTCCACAACTATTTTTTCTCAAGTTGGTTTTAGTATTAGTTTAAATACAACAACCCTCTTTCAGTCCATTTAATGCTAAGCAAACATTTCTCTCAAGCACTATTGACTATTCTGCAATGATTTATTACACAGCTAAAGCTTTTCAGTAGATAATTCATTGGTAATACGTCATACATGACTGATGGGAGGCTTTTCTGCTGCCTTTTCAGATACAGAACGCCGATGATGTCTTGATCACACCGCTGGAGAAGTTTCGCAAAGAGCAGATCGGAGCGGCCAAAG[T/C]AAGTTCTTAGAGGCCCATTGTGAGTTAATGTTGTACGTGTCAGCGGAAAGTAATTTTTACCTACGCCACGACAGGATCCTATACGGTCGGTATAGGTCTCTGAAACCCTGCAGGAAAGGGGGGAAATTGCAAACACCTGTTGAAGACGAGAGCAGCCAAATTATAGCCAGATACTGTAATGGGACATTTAACAACATGAAACGATCAGAGGGCACGTTTTAAGCAGACTCTGGTTAAAGCTTGACTCTTTCGAGGAGATTAGCTTGTTGTGCTGCTGATCTGTGAATGTGACCCTTCAGCTGGAGCTCTGCCTGTTGAGCTCAAACATTCAGAGCAAGAAAAGAAAGAAAAAAAAACAGTCCATGCCTTATTTGGGTGTATTGGCCCAATGCTTTTTAGAAGGAACTCGCTCAACTTAGACATTGAGACGTGATGGAGGCCAAAGGGAATGGCAGTCCGGCTGTTCAACCTCCTGCAGATGTGTGCATGCGTGTTCAAAG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa8901
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000079145 | Nonsense | 166 | 805 | 6 | 21 |
Genomic Location (Zv9):
Chromosome 21 (position 21884511)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 21 | 22732924 |
| GRCz11 | 21 | 22769529 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AAACACYCAGAGTATAACACTGTTTTTGAATGATTTTGTAGGCAGACACA[C/T]AGATCAGKAAGGAGAGACAGGTCTTCTATGAYGCCTCTCTCGAATAWGTT
Long Flanking Sequence:
ATGTGTGGCTTTTTAGCACTGCAAATACAGATTCTCTGGCAGTCGAAATATCACTTTAATTCTGCTGCCTTGAGTCAAATATGAGCCTGCCATCTACTGGTTATTACATTTCACTGTTTGTTTTTGTCCTATCAAATGAAAATAAACAAATTAAAGCTCTGCTGACGTTTCCATGAGACTCTCGCGTGGTGTTTGTTTACAAATCTAGCATTTTACATAACGTCTTATCTCTGCAGAAGCCATTTATCACAATAATTACAGTACAGGAAATTCCAACTCATGTCACCTTCTTTTTTCTTTTTATTTAAAGGAAGGGAAGAAGAAATTTGACAAGGAGACAGAGAAGTATTACACCGTTTTGGAGAAGCACTTAAGCCTGTCTTCAAGAAAGAAAGAATCACTTTTGCAAGAGGTAACATGAATGGTCATTTATTGCTACACAATATTAACAAACACTCAGAGTATAACACTGTTTTTGAATGATTTTGTAGGCAGACACA[C/T]AGATCAGTAAGGAGAGACAGGTCTTCTATGACGCCTCTCTCGAATATGTTTTCAAAATCCAAGAAGTACAAGAGAGGAAAAAGTTTGAGTTTGTTGAGCCGGTAAGATGCGCTTATTTATGATGAAATCAGATATACAATGAAAGCTTGCTTATACTAAGAGAGAATTACTACTTCACTTTTTTTTTCCTTTTAATCTAATGGTACATCTTGTAACATCAGCGATGTTGTTTCTCTAGAGAACATATAACGATTTAAAAAAAAAAATGATGATAACAGCCACATCCTGCAGCTCCGTCTAGATGACATTGCTTTTATATTAGAGCTGCACGGTTCTGGATACAATGAGAATCACTATTTTCTTGTTTGGACTAGGAATCATGATTCTAACACAAACTGTAAATAGCTCGTTGAACAAAATAACACACAAAAATGTGAAAAAAATGTATCTGCTGAGCTCTATTTTACAAAAAAATTATAGTTGTATAAAATATATGACAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa8645
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000079145 | Nonsense | 181 | 805 | 6 | 21 |
Genomic Location (Zv9):
Chromosome 21 (position 21884558)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 21 | 22732971 |
| GRCz11 | 21 | 22769576 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACAYAGATCAGKAAGGAGAGACAGGTCTTCTATGAYGCCTCTCTCGAATA[T/A]GTTTTCAAAATCCAAGAAGTACAAGAGAGGAAAAAGTTTGAGTTTGTTGA
Long Flanking Sequence:
ATATCACTTTAATTCTGCTGCCTTGAGTCAAATATGAGCCTGCCATCTACTGGTTATTACATTTCACTGTTTGTTTTTGTCCTATCAAATGAAAATAAACAAATTAAAGCTCTGCTGACGTTTCCATGAGACTCTCGCGTGGTGTTTGTTTACAAATCTAGCATTTTACATAACGTCTTATCTCTGCAGAAGCCATTTATCACAATAATTACAGTACAGGAAATTCCAACTCATGTCACCTTCTTTTTTCTTTTTATTTAAAGGAAGGGAAGAAGAAATTTGACAAGGAGACAGAGAAGTATTACACCGTTTTGGAGAAGCACTTAAGCCTGTCTTCAAGAAAGAAAGAATCACTTTTGCAAGAGGTAACATGAATGGTCATTTATTGCTACACAATATTAACAAACACTCAGAGTATAACACTGTTTTTGAATGATTTTGTAGGCAGACACACAGATCAGTAAGGAGAGACAGGTCTTCTATGACGCCTCTCTCGAATA[T/A]GTTTTCAAAATCCAAGAAGTACAAGAGAGGAAAAAGTTTGAGTTTGTTGAGCCGGTAAGATGCGCTTATTTATGATGAAATCAGATATACAATGAAAGCTTGCTTATACTAAGAGAGAATTACTACTTCACTTTTTTTTTCCTTTTAATCTAATGGTACATCTTGTAACATCAGCGATGTTGTTTCTCTAGAGAACATATAACGATTTAAAAAAAAAAATGATGATAACAGCCACATCCTGCAGCTCCGTCTAGATGACATTGCTTTTATATTAGAGCTGCACGGTTCTGGATACAATGAGAATCACTATTTTCTTGTTTGGACTAGGAATCATGATTCTAACACAAACTGTAAATAGCTCGTTGAACAAAATAACACACAAAAATGTGAAAAAAATGTATCTGCTGAGCTCTATTTTACAAAAAAATTATAGTTGTATAAAATATATGACACATAAAATAAATCACTCATAAAGACTTCTTTCATTACTGAATGCATTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa29585
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000079145 | Essential Splice Site | 199 | 805 | 6 | 21 |
Genomic Location (Zv9):
Chromosome 21 (position 21884613)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 21 | 22733026 |
| GRCz11 | 21 | 22769631 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCAAAATCCAAGAAGTACAAGAGAGGAAAAAGTTTGAGTTTGTTGAGCCG[G/A]TAAGATGCGCTTATTTATGATGAAATCAGATATACAATGAAAGCTTGCTT
Long Flanking Sequence:
ATTACATTTCACTGTTTGTTTTTGTCCTATCAAATGAAAATAAACAAATTAAAGCTCTGCTGACGTTTCCATGAGACTCTCGCGTGGTGTTTGTTTACAAATCTAGCATTTTACATAACGTCTTATCTCTGCAGAAGCCATTTATCACAATAATTACAGTACAGGAAATTCCAACTCATGTCACCTTCTTTTTTCTTTTTATTTAAAGGAAGGGAAGAAGAAATTTGACAAGGAGACAGAGAAGTATTACACCGTTTTGGAGAAGCACTTAAGCCTGTCTTCAAGAAAGAAAGAATCACTTTTGCAAGAGGTAACATGAATGGTCATTTATTGCTACACAATATTAACAAACACTCAGAGTATAACACTGTTTTTGAATGATTTTGTAGGCAGACACACAGATCAGTAAGGAGAGACAGGTCTTCTATGACGCCTCTCTCGAATATGTTTTCAAAATCCAAGAAGTACAAGAGAGGAAAAAGTTTGAGTTTGTTGAGCCG[G/A]TAAGATGCGCTTATTTATGATGAAATCAGATATACAATGAAAGCTTGCTTATACTAAGAGAGAATTACTACTTCACTTTTTTTTTCCTTTTAATCTAATGGTACATCTTGTAACATCAGCGATGTTGTTTCTCTAGAGAACATATAACGATTTAAAAAAAAAAATGATGATAACAGCCACATCCTGCAGCTCCGTCTAGATGACATTGCTTTTATATTAGAGCTGCACGGTTCTGGATACAATGAGAATCACTATTTTCTTGTTTGGACTAGGAATCATGATTCTAACACAAACTGTAAATAGCTCGTTGAACAAAATAACACACAAAAATGTGAAAAAAATGTATCTGCTGAGCTCTATTTTACAAAAAAATTATAGTTGTATAAAATATATGACACATAAAATAAATCACTCATAAAGACTTCTTTCATTACTGAATGCATTTTTGAATAAACTCTTAAATCTGTGGTCCTCAACCACCAGGCCAATTGGTACCAGGC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa29586
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000079145 | Essential Splice Site | 277 | 805 | 8 | 21 |
Genomic Location (Zv9):
Chromosome 21 (position 21887328)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 21 | 22735741 |
| GRCz11 | 21 | 22772346 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCTCCGGGACAGTGGACGATGGAGGGCTTTCTCTATGTACAGGAGAAAC[G/A]TGAGTGACTTCCTGTGTCAGAGCATCTATAAATAGTCTGTGTGTTTATTA
Long Flanking Sequence:
TCACAGTCTTTTAACGATTATTAAGGTGGCTCTATTTTCTACGACTCTTCAACCGGCCTGTGTGTTTCTCTCAGCTGCTGGCCTTTCTCCAGGGGCTGTTCACTTTCTACCATGAGGGTTACGAGCTGGCCCACGAGTTTGAGCCGTACAAGCAACAGCTCCAGTTCAACCTCCAGAATGTAAGAGCCGTCAGATGACGTGGGTCTGTATGAGCCGTGTTTGTATTCGGCTGTTGAGTGAACATGTAAAACTGGTGATGATAATGAGAATCAGTCATGTGGTATTTGTTGGAAGTGTTTATTGTTGCATGTGGAAGAAGCAAATGTCCCTGTTGAACCATGAGAATGTTGTTTTGATGTTCTATCCAAAGACGAGAAATAACTTTGAGAGCACAAGACAGGAAGTGGAGAATCTGATGAGAAGGATAAGATCAGCAGAGCAGGACTTTAAAGCTCCGGGACAGTGGACGATGGAGGGCTTTCTCTATGTACAGGAGAAAC[G/A]TGAGTGACTTCCTGTGTCAGAGCATCTATAAATAGTCTGTGTGTTTATTATTTAGATATATAAGTTTATATTATATTTATAAATATTTTATTTGAATAAAAATAGAGGTAAATATTTGTGCAAATATTTTTTTGGAAATATTTAATGAAAAATACATTTATATTATGTTATATTATATTATATTATATTATATTATATTATATTATATTATTTATTGATTCATTTTCTTTTCGACTTAGTCCCTTTATTTATCCTGGGTCGCCACAGCGGAATAATCCGCCAACTTATCCAGCATATGTTTTACACAGCGGATGCCTTTCCAGCTGCAACACATCATTGGGAAACATCCATATACACTCAATCACACTCATTCACTGCAGACAATTTAGCTTACCCAATTCACCTATAGCGCATGTTTTTGGATTTGTGGGGGAAACTGGAGCACCCGAAGGAAACCCACGCAAACACAGGGAGAATATCCACACAGAAATGTCAATTGA
Associated Phenotype:
Not determined