Busch Lab

ZMP

zgc:153779

Ensembl ID:
ENSDARG00000061117
ZFIN IDs:
ZDB-GENE-061103-343, ZDB-GENE-061103-343
Description:
arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 [Source:RefSeq peptide;Acc:NP_00
Human Orthologue:
AGAP2
Human Description:
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 [Source:HGNC Symbol;Acc:16921]
Mouse Orthologue:
Agap2
Mouse Description:
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 Gene [Source:MGI Symbol;Acc:MGI:3580016]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa44036 Nonsense Mutation detected in F1 DNA Not yet available
sa37768 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa12289 Nonsense Available for shipment Available now
sa44035 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa32463 Nonsense Available for shipment Available now
sa8589 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa44036
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000086813 Nonsense 286 827 8 18
ENSDART00000125104 Nonsense 286 827 8 18
Genomic Location (Zv9):
Chromosome 23 (position 36743334)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 36574811
GRCz11 23 36697272
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGAGTAGCGACTACCCCTCGTCTCTGCCTTCTACCCCTGTGATTAGTCAC[A/T]AAGACATACGGGGTGGAGCGAGTGGAGACGGGGTCACACAGCGAAACCCG
Long Flanking Sequence:
AATGTTTGTGTTTGAGCTTTCAAGCAAGCATAATTCCTGTCGGGTTCTTCTATATCTTCCTGCATATCTGTTTTTTTTATGTTTACAAATTTTTGTGGAGGGCATTGTGGCGTTTTGCTTTCCATCAGGATGCTAGTGTTGACTTGACATACTTGTTTTGTTCATAGTGACTCAAAAGATTGTGGCTGCCAAGAAACAAGCGGCTCTTCTGGCTTCCTGTAAATCTCTGCCCAACTCTCCAAGTCATTCAGGGGCCTCCACTCCGGTTTCAGGGCCCGGACAGGTACATAGGGGCTCATCGGGGGAAATTTTTATCTCCCTGTTGTGAAGTATTTGATTATTTTCAGTAATTGTGAAAGCTGTTGGTCTTCATTAGTCTGTCTTCATCATTCATCATCTCATCTCATTGTTTTCTCCATCCTATCATCTTGTAGGCCAGTAACGGGGCTCAGAGTAGCGACTACCCCTCGTCTCTGCCTTCTACCCCTGTGATTAGTCAC[A/T]AAGACATACGGGGTGGAGCGAGTGGAGACGGGGTCACACAGCGAAACCCGCCCCGCAGACGAACATCTTTATTTGCGGTTAGTTCTTTGAACTCATCACGAAAAAGAGTCATATTTCTGTGACGCTTTGGTAAACTGATATGAATACAATTAGACTTTTTTGGCATTACATTATGACCACCTCCAGCCTAAAGCAATGAGTGCACCTGGTAACTGAACACAGATGCAGTTTAGAGAGCAGTATATATAGCCATCCCAGGACTTCGGTCTCTGCTATCAGGATGGGAAAAGCTGCTGATTCATTGGAGTTTGCATTTGACAAATTTAAAAAGTGCTTTTCTTACTTAAAGTTTCTGGGCTCTATCCACTTTTGCTATTTTAAGGATGGAAAAAAACACTCTGCGCCCCGGCGCAAAACAGGATTGTGCTTATTCTCTTAATGAGTTCTGGGTGTATTTTGAGAATAAACCAATCAGAGTCTCATCTCCCATTCCCTTTAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37768
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000086813 Essential Splice Site 312 827 9 18
ENSDART00000125104 Essential Splice Site 312 827 9 18
Genomic Location (Zv9):
Chromosome 23 (position 36741252)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 36572729
GRCz11 23 36695190
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTTTCCACTTTTGTTTTATTCGTACTTTATTTAACATGTCTGCTATTGT[A/G]GAATCGGCGTGGCAGTGACTCTGAGAAAAGATCTTCAGATAGCAGAAGTG
Long Flanking Sequence:
ATGTAATTCGACAGTGCCTGAAAATAGTGCACAGCTGGGTCTGACTTTTGATAGTTTTCCACCACTGTATGTAAACACTCATTATGTTACCAGACATTACAGAAGACCTATCTCTACCTCACTAAATCAGTGCATCAAACTTTAAAGTAGGTCCTACAGGTTATTAAGTGGGCGGTCATAAAGTAATGGCTCATCTGTGTATATATTAATGATCAGGTCAGAGGTAATTTTTTTTTTTTTAACTCAGAGGTTTTTTTTTTTTTTTTTTTTTTTGATCTATCCGAACAAACTTATTCTGTAAGTCTGATGGGGAAACCTGTTCGGGCACAGTCAACATTTTCACAAAAAAAGCAGAAGCATGACAGTCTCTTTAGTATTTCTTTGTTCGTGAACTCTCTGTCATCTCTAACCATCTCATGTCATGACTCACTTCTGTTTTCTTTCTTTATGTGTTTCCACTTTTGTTTTATTCGTACTTTATTTAACATGTCTGCTATTGT[A/G]GAATCGGCGTGGCAGTGACTCTGAGAAAAGATCTTCAGATAGCAGAAGTGACACGAGCCGGTCAGTCCCTATCAAACAGGTATGCACTAAACCTCTGTGAAATCAACTGTGAAATGCAGTAGCCTACTATATGTATTTCATTAAACGCAAGAAAACTATAGGAATAAATTGGATGAAGCCACATCGTCCAACAATAATCAGTGGATAGAAATTCTAATTAAAATCAATTGCACATTTTTATGCAAAGGTGGGCACCTGTTTTTATGTATTGATATTGTTATTTATTTTATTATTTGAACTTCTGCTGCTGTCACTGAATGTCTAGTTATTTGTTTGTAAATTGCTTGTACAAGTGTTGGACAATGAAACACTGGCCAATTTAGAGTTTGAGGTTTCATGGCTAAATTTGACCAGCCTGGTGGTCAGCCTTCATTGACTGCATTTTCCACCAGTAAGAGCAGAGAAGGTTTAATAAGCAGAGTAATAGTATAGATAGATCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12289
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000086813 Nonsense 320 827 9 18
ENSDART00000125104 Nonsense 320 827 9 18
Genomic Location (Zv9):
Chromosome 23 (position 36741226)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 36572703
GRCz11 23 36695164
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTRTTTAACATGTCTGCTATTGTAGAATCGGCGTGGCAGTGACTCTGAG[A/T]AAAGATCTTCAGATAGCAGAAGTGACACGAGCCGGTCAGTCCCTATCAAA
Long Flanking Sequence:
GTGCACAGCTGGGTCTGACTTTTGATAGTTTTCCACCACTGTATGTAAACACTCATTATGTTACCAGACATTACAGAAGACCTATCTCTACCTCACTAAATCAGTGCATCAAACTTTAAAGTAGGTCCTACAGGTTATTAAGTGGGCGGTCATAAAGTAATGGCTCATCTGTGTATATATTAATGATCAGGTCAGAGGTAATTTTTTTTTTTTTAACTCAGAGGTTTTTTTTTTTTTTTTTTTTTTTGATCTATCCGAACAAACTTATTCTGTAAGTCTGATGGGGAAACCTGTTCGGGCACAGTCAACATTTTCACAAAAAAAGCAGAAGCATGACAGTCTCTTTAGTATTTCTTTGTTCGTGAACTCTCTGTCATCTCTAACCATCTCATGTCATGACTCACTTCTGTTTTCTTTCTTTATGTGTTTCCACTTTTGTTTTATTCGTACTTTATTTAACATGTCTGCTATTGTAGAATCGGCGTGGCAGTGACTCTGAG[A/T]AAAGATCTTCAGATAGCAGAAGTGACACGAGCCGGTCAGTCCCTATCAAACAGGTATGCACTAAACCTCTGTGAAATCAACTGTGAAATGCAGTAGCCTACTATATGTATTTCATTAAACGCAAGAAAACTATAGGAATAAATTGGATGAAGCCACATCGTCCAACAATAATCAGTGGATAGAAATTCTAATTAAAATCAATTGCACATTTTTATGCAAAGGTGGGCACCTGTTTTTATGTATTGATATTGTTATTTATTTTATTATTTGAACTTCTGCTGCTGTCACTGAATGTCTAGTTATTTGTTTGTAAATTGCTTGTACAAGTGTTGGACAATGAAACACTGGCCAATTTAGAGTTTGAGGTTTCATGGCTAAATTTGACCAGCCTGGTGGTCAGCCTTCATTGACTGCATTTTCCACCAGTAAGAGCAGAGAAGGTTTAATAAGCAGAGTAATAGTATAGATAGATCCTGCTGGCGCATCTGTGACCAGAACAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44035
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000086813 Essential Splice Site 515 827 13 18
ENSDART00000125104 Essential Splice Site 515 827 13 18
Genomic Location (Zv9):
Chromosome 23 (position 36734221)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 36565698
GRCz11 23 36688159
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAACCGAAGTATTAATCTGAAAGGAGATGCAGCGGCCGGTCAGGCTGAAG[G/T]TAGCAGACCGTACCATTGATCTACTATCACTGATAATAAAGCCATCTGAT
Long Flanking Sequence:
GGTTTGACAAATATAGCGAGATTAGATCTAGCGGTAGATCCTTGATGAACAGTCCGACGTGCACAGCCCTCATTGCTGCAGTACATGTGTGTGTGTGTGGTCACATGATGTGCATTTTCAGTGGTATAATGTGCACGGAGAGCTGTTCTGAAACGCTAGTGTGGACGCGGATTGTTTTCATTCTAAAACGCCATTTTAAAACTAAAACATACTAGTGTAAACGGGGCCTAAAGTACTGTTTTGTTAATTTTGTAATAGTTTAATTAATCTTTCTATATTTAATAAAAAATACAGTAAATGACACAACTGGAGCATGAAACATTATGATAAAAACACTATGATTTTTTTTTTTTTTGTAATAGACTCAAGCATCGAGGGAGCCACAAGTCCTCCTTTAGGAAAAGAGCACATGCCGTCTTCTCCAATGACTGACCGGAAGAAGAAGAAGCGAAACCGAAGTATTAATCTGAAAGGAGATGCAGCGGCCGGTCAGGCTGAAG[G/T]TAGCAGACCGTACCATTGATCTACTATCACTGATAATAAAGCCATCTGATGTTTTATTGAGAAGAGTTTGCAGATTTGCTTTCCTCTGCTTTTCTTTATGATTGCAGTGTGGACCTGATTAATTATTGCTTTCTCTAAGGTCCAATCTCTTTTACTTCTTTCTTCTCTTCACTTTTTTTCCTCTTATCCTCTGCTGCCGTGGACTAATTTCTTGCACCGCAAGCCAAGCGCAAAATGTGGAAATTAAAAAGCTTTGGTAGCTTGAGAAACATTAACAAAACAGGTAACTTGAATGTATGAAGCGTGTAAACGGTGTAAAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATTTTCTCTGACTAAAATATATTTTAAATATATTGTGTAAATGTAAACGTATTCAATTTCAGCCTTAATAAACCTAAATGTATTTCATGGTCAGGGAAATACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32463
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000086813 Nonsense 584 827 15 18
ENSDART00000125104 Nonsense 584 827 15 18
Genomic Location (Zv9):
Chromosome 23 (position 36727940)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 36559417
GRCz11 23 36681878
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAGGAACAGCCAAAGTGAAGCTGTTGCCCTGCAGGCCATTCGAAACGCC[A/T]AAGGGAACGACCTCTGTGTGGACTGTGCAGCACCAAGTAAGCCTGTCCTA
Long Flanking Sequence:
AACCATTCTCAAAAACCAAAATCATTCTGTTGAACACAGAATAAGATATTCTGAAGAATGTTGGAAATGTGGTATAAAATTACTACAAATATCAATGGCTGCTGCTTTTTTCCAACATTTTTTTTTAAATAGCTTCCTTTGTGTTCAACAAAAGCAAGAATAGAGTTTTCCATTTTGGTTGAACTATACTTTTAACAATAATTTAAAAAAACTCCTTGTTTTTGGTAGCACCAAAAACACATTTACTTGTGCGTCTCTTTAAATGCAAATGAGCTTCTTCTTCCCGCCCCATTTCCAGAAGAGGGAGGAGCCTTTACAGCTCTTGCCTCAGTTAACAACAAACAAACAAAACATGCATGCCTGCTTAATCCTACATACAAAACACATATTAGGAAGCAACACACTGGAGATATTACAAATTAATAGACTTCATTTTCATCTCTCAGGCTCGAAGGAACAGCCAAAGTGAAGCTGTTGCCCTGCAGGCCATTCGAAACGCC[A/T]AAGGGAACGACCTCTGTGTGGACTGTGCAGCACCAAGTAAGCCTGTCCTATATTATAATGAGAACGAAATCAATAAAAAGCCAATGTCAAATTTTTTGTCATTGATATTGTGGTCTCCTTGCAGATCCAACATGGGCAAGTCTTAATCTGGGCGCTCTAATCTGCATTGAGTGTTCAGGGATACATCGAAATCTGGGCACGCACCTGTCCCGCGTGCGCTCGCTAGACCTGGACGTCTGGCCCAGTGAGCTCACTAAAGTTCTTTCGGCTATAGGAAACCACATGGCCAACCATATTTGGGAGACTTGTACACAGGGGTGTCAGAAATTGACGCCTGAAGCAACAAGGTGAGGTTGTCAATAAAATCAGTGGAAAAAAAACTAAACATTTTTTAAACAAATATTGCAGAAACTTTATGTAAAATAAAATATATATTTTGCAAGGTATGTACAGTTAAGTGTAAGAAAATATGCCTAAAGCAATATTATATTTTATTATTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8589
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000086813 Nonsense 680 827 17 18
ENSDART00000125104 Nonsense 680 827 17 18
Genomic Location (Zv9):
Chromosome 23 (position 36725953)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 36557430
GRCz11 23 36679891
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTTTATTTTGTGTTGGTCTCAGAGAGCAGAGGGAGTCGTGGATCCGTGCC[A/T]AATACGAACAGCGAGCRTTTGTGTCGCCCTTGCCTGCTCAGTGTTCAGAG
Long Flanking Sequence:
ATGATTTATTATTATTATTAATTTTTCTTTATTTATTTGTTTATTTGGCAGGAACAGTGTACATTAATTAGCATTTCTGCAAATGCACCAGAAAATCCTAAATCTGTTTAATCATTAAATAATTAATTCATGTGATGGCAAAACCGGCTTTTCTCTCTCACACGATCTTTTAGAAATAAATATGTTAATATGCAAATCAATTTGCTGCACAAGTTCTGCTTGATACACTTGATAGAAATTGTGATAAAATAATTCAACATTTGTTGATAAATAGAATATTTAAAATATTATAATAAATAACAGAAATCAAAAACAAAATTTGTTAGATTCATTTCATTTAAAATATTTTACTGACCTCATTATATTTAAAGAATTATAAGATTAAATTAAATAAAATAAATAAATAAATAAAAAAGCTAATGTGGTTCGCCACTCAATTAATTATTTGGCCTTTATTTTGTGTTGGTCTCAGAGAGCAGAGGGAGTCGTGGATCCGTGCC[A/T]AATACGAACAGCGAGCATTTGTGTCGCCCTTGCCTGCTCAGTGTTCAGAGGACACGATGTCCACTTGGTTGCTTAAAGCAGTCATCAACAGGGATCTTCCCAATCTTCTACTGCTCCTTGCTCACAGCACCAAGGAGCTGATCAACATCCCGCCGGAAGGAGCAGGACAGCAGCATCACAGCGCCTTACACGCGGCCTGCCAGCTGGGAGACGTGGTCATGACACAGCTGTTGGTCTGGGTAATTCACCGTTTACAGCTTCTGTTTACACATACTTTTCTTTTTCAGTCCAATCACAAAAGGAGGATATTAAATACAAGGATCTGAAATGTTTTGAGCTTGTGCACTTTCGACCACTGCCAGAGGAATTTTTAAAAATGTAATATATCAAAGTTTTCACCAATCATGTCATATACAGTTGAAGTGAAGATTATTAGCTCTCCTGTGATTTTATTTTATTTTTTCCAAATATTTCCCAAATGACATTTAACAGAGCAAAGA
Associated Phenotype:
Not determined