Busch Lab

ZMP

piwil1

Ensembl ID:
ENSDARG00000041699
ZFIN ID:
ZDB-GENE-030813-2
Description:
Piwi-like protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q8UVX0]
Human Orthologues:
PIWIL1, PIWIL3
Human Descriptions:
piwi-like 1 (Drosophila) [Source:HGNC Symbol;Acc:9007]
piwi-like 3 (Drosophila) [Source:HGNC Symbol;Acc:18443]
Mouse Orthologue:
Piwil1
Mouse Description:
piwi-like homolog 1 (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:1928897]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa8531 Nonsense Mutation detected in F1 DNA Not yet available
sa7619 Missense Mutation detected in F1 DNA Not yet available
hu2479 Nonsense Confirmed mutation in F2 line Not yet available
hu4333 Nonsense Confirmed mutation in F2 line Not yet available
sa30904 Nonsense Mutation detected in F1 DNA Not yet available
sa45333 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa8531
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000061115 Nonsense 128 858 4 20
ENSDART00000133021 None None 231 None 7
ENSDART00000138019 Nonsense 128 858 5 21
ENSDART00000139249 None None 180 None 5
ENSDART00000145076 Nonsense 128 373 6 12

The following transcripts of ENSDARG00000041699 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 45902300)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 44241189
GRCz11 8 44234608
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTGAGGGCCAATTTYATGCGTCTGCTTTCACGTCCTATGTGGGCTTTRTA[T/A]CAGTATCATGTGGACTAMAAGCCACCAATGGAGTCCAGACGACTGCGTTC
Long Flanking Sequence:
ATTAAAAATGTGTACATACACCGTCAATGCACCGTGATGCACCGAGATATCGAATTGAACCGAATCGATGGCATGATAATCGTAACCGAACCGAACTGTGAGACTAGTGTAGGTTCACACCCCTAAATAATAAATAATTGACTTTTTCTCTATCTTTATTAGTTTCAAAAACAGATTTATTTACAAAACATAAAAAAACACACACACATGAAAAAAACCTTACTATATAACAGAAAAAGTTATCCTTTTTTAAACCCTTTGTTTCTATACCGTGGTAAAAAATGCCGAACTTCTGTTAAAAAACTTAATACAAAAATAACGAAACCTCTAACAGACCCCAGAACTTTTTCACATACCTGTTCAGGTTGTCTACCTCAGTTGTTGAAATATAGTGTAATGCTATATTTGACACTTTCTTTGACTACAGGTGTTTCTGGGACTGCCATTGAGCTGAGGGCCAATTTTATGCGTCTGCTTTCACGTCCTATGTGGGCTTTGTA[T/A]CAGTATCATGTGGACTACAAGCCACCAATGGAGTCCAGACGACTGCGTTCGGCTTTGCTTTTCCAGCACGAGGAGACTCTGGGGAAAGCACACACCTTTGATGGAGCCATTCTCTTTCTCCCCAACAAACTGCGCAACGCTGTATGTTTGTAGAGTCTTAACATTTTATTTAACCTCTTACAGTGCTTTCACACCAGATACAGATGAAGTGTAAAGGGCAAATAATTTACATGTTAAGTCTATGCAAAGACTTAGATATCCTGCAGCATGGTTTGTTAGAATGGGGTGGCATGAATGACCAACTTGAGGGAATGACACATTGCAAACTGCATTCGGGGCAATTGAAGCACTTTAAAAATTGGAACTTTGGCATAAATTCATGCCATGTTAAAGGAATACTCCACTTTTTTTGAAAGGCTCTTAAAAGTTTTCCAGAGTTAAACAGTTGACTTTTTGAAACCATTTAGTTGGATGATTGTTTTGGCTTGGTCACGTTTAGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa7619
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000061115 Missense 155 858 4 20
ENSDART00000133021 None None 231 None 7
ENSDART00000138019 Missense 155 858 5 21
ENSDART00000139249 None None 180 None 5
ENSDART00000145076 Missense 155 373 6 12

The following transcripts of ENSDARG00000041699 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 45902380)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 44241109
GRCz11 8 44234528
KASP Assay ID:
554-4021.1 (used for ordering genotyping assays)
KASP Sequence:
GGAGTCCAGACGACTGCGTTCGGCTTTGCTTTTCCAGCACGAGGAGACTC[T/A]GGGGAAAGCACACACCTTTGATGGAGCCATTCTCTTTCTCCCCAACAAAC
Long Flanking Sequence:
CGTAACCGAACCGAACTGTGAGACTAGTGTAGGTTCACACCCCTAAATAATAAATAATTGACTTTTTCTCTATCTTTATTAGTTTCAAAAACAGATTTATTTACAAAACATAAAAAAACACACACACATGAAAAAAACCTTACTATATAACAGAAAAAGTTATCCTTTTTTAAACCCTTTGTTTCTATACCGTGGTAAAAAATGCCGAACTTCTGTTAAAAAACTTAATACAAAAATAACGAAACCTCTAACAGACCCCAGAACTTTTTCACATACCTGTTCAGGTTGTCTACCTCAGTTGTTGAAATATAGTGTAATGCTATATTTGACACTTTCTTTGACTACAGGTGTTTCTGGGACTGCCATTGAGCTGAGGGCCAATTTTATGCGTCTGCTTTCACGTCCTATGTGGGCTTTGTATCAGTATCATGTGGACTACAAGCCACCAATGGAGTCCAGACGACTGCGTTCGGCTTTGCTTTTCCAGCACGAGGAGACTC[T/A]GGGGAAAGCACACACCTTTGATGGAGCCATTCTCTTTCTCCCCAACAAACTGCGCAACGCTGTATGTTTGTAGAGTCTTAACATTTTATTTAACCTCTTACAGTGCTTTCACACCAGATACAGATGAAGTGTAAAGGGCAAATAATTTACATGTTAAGTCTATGCAAAGACTTAGATATCCTGCAGCATGGTTTGTTAGAATGGGGTGGCATGAATGACCAACTTGAGGGAATGACACATTGCAAACTGCATTCGGGGCAATTGAAGCACTTTAAAAATTGGAACTTTGGCATAAATTCATGCCATGTTAAAGGAATACTCCACTTTTTTTGAAAGGCTCTTAAAAGTTTTCCAGAGTTAAACAGTTGACTTTTTGAAACCATTTAGTTGGATGATTGTTTTGGCTTGGTCACGTTTAGCTTAGCATAATTCATTGAATCAGATTTGACCATTGGCCTTTCGTTTAAATGTATTTTTATTTTAAATTTATTTATTTTTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
hu2479
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000061115 Nonsense 544 858 13 20
ENSDART00000133021 Nonsense 222 231 7 7
ENSDART00000138019 Nonsense 544 858 14 21
ENSDART00000139249 Nonsense 135 180 4 5
ENSDART00000145076 None None 373 None 12

The following transcripts of ENSDARG00000041699 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 45906712)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 44236777
GRCz11 8 44230196
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCAGGATTGAGTATGAAGATCGTCAGGAATCTCTCCTTAGAGCTTTGCAA[C/T]AAAACGTAGCACGTGAAACTCAGATGGTAAGTCGAGTATTCATGTAATAT
Long Flanking Sequence:
TAATTAGAAAAATGTCTTTTTTAAATTGCTCCATGGAAACGCAGTGTCCCTGAGTCAGATTAACACTGCATTTTTATCAAAAAAGTACAGTATTTTAGTTGTATAAATGAGGAGAGACAACTTGACCTCCAGCATGCATTCATAACACTTATCCTGAAACCTCAATTACTCTTGTCTTTCATCTCATAGTTTGAGTATAACCCATGGACAGCAGACTGGTCTAAAGAGATGAGAGGTCTCCCTCTGATTAGCTGCATGTCTCTGGACAACTGGCTCATGTTCTACACGCGCAGAAATGCAGATGTTGCCCAATCTCTGCTTCAGACTCTCAACAAAGTGTCTGGACCCATGGGGATCCGCATGCAGAGGGCTGTCATGTGAGTTGTGGTCGACTTTAAATGTGAACTACTTTTCAGTCTGTTCTCATGTTAATAAGCATTTCCTGACCAAGCAGGATTGAGTATGAAGATCGTCAGGAATCTCTCCTTAGAGCTTTGCAA[C/T]AAAACGTAGCACGTGAAACTCAGATGGTAAGTCGAGTATTCATGTAATATTGATTGTCCAGCAACTTTTTTTTTATTATTGCTTTTGTGCCTCTGTAGGTGGTGGTGATCTTGCCTACCAATCGAAAAGACAAGTACGACTGTGTAAAGAAGTACCTGTGTGTGGACTGCCCTACTCCTAGTCAGTGTGTGGTGTCTCGCACCATCAGCAAACCTCAAGCACTTATGACTGTGGCCACCAAGATTGCTTTGCAGATGAACTGCAAAATGGGAGGAGAGCTGTGGAGTGTAGAAATTCCAGTAAGGGTTTAAGACAATACACTATAATGCATCCTTCAACAACATCCTCAGTTCTTTCCTCAATAATCAACCTTTGTCTTTCAGCTCCGGCAGCTCATGATTGTAGGTATAGACTGCTACCATGATACCGCTGCTGGAAAAAGGTCCATCGGCGCAATGGTGGCCAGTCTAAATCAGGGCATGTCAAGGTAAGTCATTTAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
hu4333
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000061115 Nonsense 544 858 13 20
ENSDART00000133021 Nonsense 222 231 7 7
ENSDART00000138019 Nonsense 544 858 14 21
ENSDART00000139249 Nonsense 135 180 4 5
ENSDART00000145076 None None 373 None 12

The following transcripts of ENSDARG00000041699 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 45906712)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 44236777
GRCz11 8 44230196
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCAGGATTGAGTATGAAGATCGTCAGGAATCTCTCCTTAGAGCTTTGCAA[C/T]AAAACGTAGCACGTGAAACTCAGATGGTAAGTCGAGTATTCATGTAATAT
Long Flanking Sequence:
TAATTAGAAAAATGTCTTTTTTAAATTGCTCCATGGAAACGCAGTGTCCCTGAGTCAGATTAACACTGCATTTTTATCAAAAAAGTACAGTATTTTAGTTGTATAAATGAGGAGAGACAACTTGACCTCCAGCATGCATTCATAACACTTATCCTGAAACCTCAATTACTCTTGTCTTTCATCTCATAGTTTGAGTATAACCCATGGACAGCAGACTGGTCTAAAGAGATGAGAGGTCTCCCTCTGATTAGCTGCATGTCTCTGGACAACTGGCTCATGTTCTACACGCGCAGAAATGCAGATGTTGCCCAATCTCTGCTTCAGACTCTCAACAAAGTGTCTGGACCCATGGGGATCCGCATGCAGAGGGCTGTCATGTGAGTTGTGGTCGACTTTAAATGTGAACTACTTTTCAGTCTGTTCTCATGTTAATAAGCATTTCCTGACCAAGCAGGATTGAGTATGAAGATCGTCAGGAATCTCTCCTTAGAGCTTTGCAA[C/T]AAAACGTAGCACGTGAAACTCAGATGGTAAGTCGAGTATTCATGTAATATTGATTGTCCAGCAACTTTTTTTTTATTATTGCTTTTGTGCCTCTGTAGGTGGTGGTGATCTTGCCTACCAATCGAAAAGACAAGTACGACTGTGTAAAGAAGTACCTGTGTGTGGACTGCCCTACTCCTAGTCAGTGTGTGGTGTCTCGCACCATCAGCAAACCTCAAGCACTTATGACTGTGGCCACCAAGATTGCTTTGCAGATGAACTGCAAAATGGGAGGAGAGCTGTGGAGTGTAGAAATTCCAGTAAGGGTTTAAGACAATACACTATAATGCATCCTTCAACAACATCCTCAGTTCTTTCCTCAATAATCAACCTTTGTCTTTCAGCTCCGGCAGCTCATGATTGTAGGTATAGACTGCTACCATGATACCGCTGCTGGAAAAAGGTCCATCGGCGCAATGGTGGCCAGTCTAAATCAGGGCATGTCAAGGTAAGTCATTTAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa30904
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000061115 Nonsense 565 858 14 20
ENSDART00000133021 None None 231 None 7
ENSDART00000138019 Nonsense 565 858 15 21
ENSDART00000139249 Nonsense 156 180 5 5
ENSDART00000145076 None None 373 None 12

The following transcripts of ENSDARG00000041699 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 45906849)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 44236640
GRCz11 8 44230059
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGCCTCTGTAGGTGGTGGTGATCTTGCCTACCAATCGAAAAGACAAGTA[C/A]GACTGTGTAAAGAAGTACCTGTGTGTGGACTGCCCTACTCCTAGTCAGTG
Long Flanking Sequence:
ATTCATAACACTTATCCTGAAACCTCAATTACTCTTGTCTTTCATCTCATAGTTTGAGTATAACCCATGGACAGCAGACTGGTCTAAAGAGATGAGAGGTCTCCCTCTGATTAGCTGCATGTCTCTGGACAACTGGCTCATGTTCTACACGCGCAGAAATGCAGATGTTGCCCAATCTCTGCTTCAGACTCTCAACAAAGTGTCTGGACCCATGGGGATCCGCATGCAGAGGGCTGTCATGTGAGTTGTGGTCGACTTTAAATGTGAACTACTTTTCAGTCTGTTCTCATGTTAATAAGCATTTCCTGACCAAGCAGGATTGAGTATGAAGATCGTCAGGAATCTCTCCTTAGAGCTTTGCAACAAAACGTAGCACGTGAAACTCAGATGGTAAGTCGAGTATTCATGTAATATTGATTGTCCAGCAACTTTTTTTTTATTATTGCTTTTGTGCCTCTGTAGGTGGTGGTGATCTTGCCTACCAATCGAAAAGACAAGTA[C/A]GACTGTGTAAAGAAGTACCTGTGTGTGGACTGCCCTACTCCTAGTCAGTGTGTGGTGTCTCGCACCATCAGCAAACCTCAAGCACTTATGACTGTGGCCACCAAGATTGCTTTGCAGATGAACTGCAAAATGGGAGGAGAGCTGTGGAGTGTAGAAATTCCAGTAAGGGTTTAAGACAATACACTATAATGCATCCTTCAACAACATCCTCAGTTCTTTCCTCAATAATCAACCTTTGTCTTTCAGCTCCGGCAGCTCATGATTGTAGGTATAGACTGCTACCATGATACCGCTGCTGGAAAAAGGTCCATCGGCGCAATGGTGGCCAGTCTAAATCAGGGCATGTCAAGGTAAGTCATTTAAACATGGTATTGTTAAATTAATGCTAGATTATTAGTTGAATATTAGACTGGTATGAATATCTTGGACTGGTTAGAGCAGGTCCTAGAGCTTAACTTAGAGCCTCTTTGGTGAATGCATCTAATTGAATTTACAGAAGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa45333
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000061115 Nonsense 698 858 17 20
ENSDART00000133021 None None 230 None 7
ENSDART00000138019 Nonsense 698 858 18 21
ENSDART00000139249 None None 180 None 5
ENSDART00000145076 None None 373 None 12

The following transcripts of ENSDARG00000041699 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 45908516)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 44234973
GRCz11 8 44228392
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGGCCTATCTGAAATACAACAATTCTCTGCCCTCGCGCATCATTGTTTAC[C/T]GAGATGGAGTTGGAGATGGCATGCTGCAGAGCGTTGTGGACTATGAAGTT
Long Flanking Sequence:
GCACACACAGTATGTTTATCTGCTTTAAGAACAGCGATATTACTACCACAATTTTCAGAAACTTCTTGTGCTCATCAGGTTTGTAACATTTATGAATAAATTCAGTGTTGTGTATATGTAACTATTTGTATGGATGATCTGTGCAATTTTAGAAACAGTGTTTTTATTTTTCTTAAAAAATGTCAATTTTGATTGTTTATGTAAAGTGAGCCAGTAAAAACAGATACACAGTTTGGGCAATTCATTTGTGATTAACAGTAGCTCAATTAAATAATTTAGTCTGGTTACATTCACATCAGAAATTACCTGTGGTTTTGCATGAACTGTTCTCAGACCACCCTTTTTGGGTGGAATCCAGCATGTTTCACAGGTGCACACCTCAGTCCAGAAAATATCTTTTACATGAACTAAAACATACTTGATATCCAACTGTCTTTTTAGGTGCTCTGAAGGCCTATCTGAAATACAACAATTCTCTGCCCTCGCGCATCATTGTTTAC[C/T]GAGATGGAGTTGGAGATGGCATGCTGCAGAGCGTTGTGGACTATGAAGTTCCTCAGATCATGCAGTCTATCAAGACCATGGGGCAAGATTATGAGTAAGCCAGCCTTCATGCAGACACACTCACACTATAGGAATGATACATTTTCTTCATTGTTTTAATGTTTTTCTTTACAGGCCCAAGCTCTCAGTAGTGGTGGTGAAAAAGCGCATCAGCTCCCGATTCTTTGCTCGGATTGATGGCAAAATTGCCAATCCCCCTCCTGGGACAGTCATTGACACTGAAGTCACTCGTCCAGAGTGGTGCGTGTAGAGTACCCTGAAGGAACACTGCTCATTCTCAAACAAGCATTGCCCGATTAGTACATTTTTCTTTCACTTGGCCATCCAAAACATTCAGTTGTCCCGGTCAAGCATTAATACTGAACTTTGAATTCCTACTAATTGTTCATGGTACCGCTTACTTTTTTTTATGCATAAACTGGATTTTGTTGATACAGTAG
Associated Phenotype:
Not determined