Busch Lab

ZMP

LOC563188

Ensembl ID:
ENSDARG00000061956
Human Orthologue:
SYTL2
Human Description:
synaptotagmin-like 2 [Source:HGNC Symbol;Acc:15585]
Mouse Orthologue:
Sytl2
Mouse Description:
synaptotagmin-like 2 Gene [Source:MGI Symbol;Acc:MGI:1933366]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa27625 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa13534 Essential Splice Site Available for shipment Available now
sa8436 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa27625
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000088973 Essential Splice Site 370 909 11 27
Genomic Location (Zv9):
Chromosome 10 (position 29995631)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 29368075
GRCz11 10 29254700
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GATGAGAACAAACCAGACAAACTCTGTGAAGAACCTTCTCAACAAGAAAG[G/A]TTTGACCAAGATGAAGTATCAACGGGAAGACTGGTCAACCTGAAGTCATT
Long Flanking Sequence:
CAGTCGTCACAGGTGTCCAATATCCACACGTCTACTGAAGAAGCAGGTAAGACCACTGAGTTGAGCACAGAAGTGAAGACTGATAAGGTTACAGTGGAAGAGGATCGCTCCATTTTAAAGGTATTTGACTGGTTTGGAAAAGGTTCTCGGGATGGAAAGCTAAAGGAGTTGCCAACCAAAAAAGAGTTGAATGAAGAGGAACCAAAACCTGATGAAAGTCTTGTAACAAAGTCAGATGATTCAGAGGCTCCAGATGTACACCTAAAGACCACTAAGCCAGTACCAAAGCCACGCAGGGGGCTTTTTGCAATGTTTTCGAGAGCAGAAAATAAAGACAAGAATCCTGAAGTTCAGGCATCAGAAAAAGCTAAATGTGAAACAGAAGCCAATGATAATATACTCGAGCAGATCTCTTTTCCTACAGAGAACAGGATGGCTGAAATATTACAGGATGAGAACAAACCAGACAAACTCTGTGAAGAACCTTCTCAACAAGAAAG[G/A]TTTGACCAAGATGAAGTATCAACGGGAAGACTGGTCAACCTGAAGTCATTCTGGGAAAGGGGGGACAGAGGACCTAAAATACTGAGCATGAAAAAAGAAGATGAGGAAGAAGAAAGTGAGACATCTCAGCTTAATGAAAATTATCATAACACAACACAGTCTGACATGTTGTCAGACTCCAGCACTAGCCTGTCGAAACCCAAACTCAGTGATCCAGAACCAGCTGATGTTGAATCTACATTAATTGGGTCTTCTTTGATCTCACCTAGAAGAACATCCAATGGTGTTGCCATATCCTTGCTTGAAGATGAAGAACCTTTTATTTTGGACAACCATAAGGCCTCTGAAAACTCAAGCAGTAAGCTACATACTCTTGTTGAGTATAATGCGCTAGACAGTGATCAACAAGAAGAATCAATCTGCAGGGATATATCTGACCTGAAGAAGGAAATCTCCACCCTCAAAATATCTATCAGTCAACATGAAGATAAAGTCTCGAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13534
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000088973 Essential Splice Site 380 909 12 27
Genomic Location (Zv9):
Chromosome 10 (position 29995991)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 29368435
GRCz11 10 29255060
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GAAGAACCTTTTATTTTGGACAACCATAAGGCCTCKGAAARCTCAAGCAG[T/A]RAGCTACATACTCTTGTTGAGTATAATGCGCTAGACAGTGATCAACAAGA
Long Flanking Sequence:
GAAAAAGCTAAATGTGAAACAGAAGCCAATGATAATATACTCGAGCAGATCTCTTTTCCTACAGAGAACAGGATGGCTGAAATATTACAGGATGAGAACAAACCAGACAAACTCTGTGAAGAACCTTCTCAACAAGAAAGGTTTGACCAAGATGAAGTATCAACGGGAAGACTGGTCAACCTGAAGTCATTCTGGGAAAGGGGGGACAGAGGACCTAAAATACTGAGCATGAAAAAAGAAGATGAGGAAGAAGAAAGTGAGACATCTCAGCTTAATGAAAATTATCATAACACAACACAGTCTGACATGTTGTCAGACTCCAGCACTAGCCTGTCGAAACCCAAACTCAGTGATCCAGAACCAGCTGATGTTGAATCTACATTAATTGGGTCTTCTTTGATCTCACCTAGAAGAACATCCAATGGTGTTGCCATATCCTTGCTTGAAGATGAAGAACCTTTTATTTTGGACAACCATAAGGCCTCTGAAAACTCAAGCAG[T/A]AAGCTACATACTCTTGTTGAGTATAATGCGCTAGACAGTGATCAACAAGAAGAATCAATCTGCAGGGATATATCTGACCTGAAGAAGGAAATCTCCACCCTCAAAATATCTATCAGTCAACATGAAGATAAAGTCTCGATTAATGATCTCAAATCCTTTTGGGAGAAAGAAAAAGGTGGTCTTAGAGTAATTGTAAGCTCTCAAACATGCACAGCCAATGTTAAAGACCCATCCCCCGAGCCATCTCCAAATCGTTCTTTAGGAAGACTGTCTGAACCTCAGTTTGACATCAGGTCAAACAACCCAAGTTCTCCGGACAGAAGAATTTTTAAAGAGTTTAATTTGATTGAGCAAAAACTGAAGATGGAAAAGGTTGAAGACAAACAAAGAAGTGAAAATACAGTGCCATTACAAGACCTTCAAGACATCAGAGGTAGGGTACCTCACATCATGCAGAATCTTTCTAATATTGAACAGTTTATTGCAGACCCACATTCCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8436
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000088973 Nonsense 810 909 26 27
Genomic Location (Zv9):
Chromosome 10 (position 30004578)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 29377022
GRCz11 10 29263647
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
YGCAATCCTCCCAGAGAACAACAGGAAAAGCCGTCAGAAGACCAGAGTGT[T/A]GAAGAGGGCTCCAAACCCAGTGTTTAACCACACCATGGTTTATGATGGCT
Long Flanking Sequence:
CATATTTAACATATCAGGCAGGTTGCAGAATAGTACTGTAATTCCAGCCCGATCTCCTGAAAAAAACGTAAGTATTTAACGTTTTGTCAGTTTAGTCGCTAATTCGTACGATTTTGTACGAGTTGAGTCATACGAAATTGTACGATTTTAAAAAGGAGGCGTGGCACCCATCTCTGCCACTAAACCCAACCGTCATAGGGTGATGAGCAAATCGTACTAAATTGTATGAATTATATTGTACCAATTCATACAAATTAGCCACTAAAACAAAAAGTTGTGAATTGCCGTGAGGTTGCGTTGGTAATTCTAGTTCATTCTAAAAAAAATTCAGTTAAGTTTAGTATAAATGTCAGTGTTGAATGAGGATCCACTAAAGGGCAGCTCTACCAACTACAACCAAGCAAGCCATTGAAGTACTAGAGCTCATTTGTGCGAATTCTTACTTTTCAGTGCAATCCTCCCAGAGAACAACAGGAAAAGCCGTCAGAAGACCAGAGTGT[T/A]GAAGAGGGCTCCAAACCCAGTGTTTAACCACACCATGGTTTATGATGGCTTCGGGCATGACGACCTTAAAGACATCTGTGTGGAGCTTACGGTGTGGGATCATGACAGACTGAACAACCACTTCATTGGGGGTATCAGACTTGGACCTGGAACAGGTAAATAAAGGGCCAATTAAAAACATTTTTCTGAAAATAATGGTCAGCCTAATTTTCAGTTTTACCTCATTTCAGGTAAAAGTTATGGCAGTGAAGTAAACTGGATGGACTCTAACGTTGCTGAAGCAGCCCTGTGGGAGAGAATGGTGCAAACTCAAAATGAATGGGTGGAAGATACATTACCTTTGAGAATGATGGTCATGGCAAGAATGTCTAGATAGTAAGAAACCGAGGACACCTTTGAACAAACACATCAAAACAAACATGAACATGAAGAATTCAGTATGTAGAAAAACTATATATGTAATGTTTAATATATAGAAACTAACGTGATGTTTTCTTGAC
Associated Phenotype:
Not determined