Busch Lab

ZMP

nadl1.1

Ensembl ID:
ENSDARG00000015025
ZFIN ID:
ZDB-GENE-980526-512
Description:
Neural cell adhesion molecule L1.1 [Source:UniProtKB/Swiss-Prot;Acc:Q90478]
Human Orthologue:
L1CAM
Human Description:
L1 cell adhesion molecule [Source:HGNC Symbol;Acc:6470]
Mouse Orthologue:
L1cam
Mouse Description:
L1 cell adhesion molecule Gene [Source:MGI Symbol;Acc:MGI:96721]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa12283 Nonsense Available for shipment Available now
sa756 Essential Splice Site Available for shipment Available now
sa39389 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa37581 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa12283
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000026177 Nonsense 664 1264 17 33
ENSDART00000055130 Nonsense 619 1224 14 26
ENSDART00000055131 Nonsense 664 1269 17 29
ENSDART00000132175 Nonsense 727 1332 17 29

The following transcripts of ENSDARG00000015025 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 623496)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 594487
GRCz11 23 607280
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGAGTATGTGATTGAGATGAACGAGGGGGAGACTCCAGWCGAGGGTCAAT[G/A]GCAGAAATACAGGAGTGTTTCTCAGGACATCCGWCAGCTGGAGWTCCACC
Long Flanking Sequence:
GGGTTCAAATCCCGGACGAGCCCCCAATTTCTGCTATGATCTCTAGGGTTTGGCCGTTAAAGAAAAACAGTGGGCGTGGCTTGTTTTTTCTACTGCGAGCTGATTGGATGTAGTAAAGTAGGTGTTTTATTCAGAAAGATGGGGAAAAGGGTTTGGGGAGAGTTATTACCGCCTAACAGACTCCTCCTGCTCACCAATTGTTTGATTTCAAAACTGACTGCTGGAGGGGCGTGGTTAAACGTGTTAGCCCCACCCAATACCTCAGACATGCCTAATCTGAGAATTGAACTGAAACAGAAATTGAAATTACAGGAGCAAACTATTGTTTTTGTCCTAATGACATGCACAGATGAACTGTTCAGCACAAAACTAGCAATGTGAGATAACAATTTTACTATGGCTTGTTTTGATTTCATGTGTACTTTAAACACTTTATTTCTGTTGTCCTGCAGAGTATGTGATTGAGATGAACGAGGGGGAGACTCCAGACGAGGGTCAAT[G/A]GCAGAAATACAGGAGTGTTTCTCAGGACATCCGACAGCTGGAGATCCACCTGCAGCCCTACAGCAAATACCACTTCCAGATCCGGGCAGTGAACAGCATAGGAACCAGTGCTCCCAGCGAGTCCTCGCTCTCCTACAGCACTCCAGCAGCCAGTAAGATGGGTTTTACAACCTTTTCTGTTTTTTTGGCAGAATATACCATTTAATTTAAGGGATTTTTAAACTTATAGGTAAAAAATCTTACTTACTAACTTACTTACAGACTTACTTACTGACTTACCTACCTACCTACCTACGTACCTACCTAACTACCTACCTATGTACTTACTTACTGACTTACCTACCTACGTATCTACCTACCTAAGTACGTACTTACTTACAGACTTACCGACCTACCTACCTATCTACATACTTACTTACTGACTTACCTACCTACGTACCTACCTACCCACCTACCTACGTACCTACCTATGTACCAACTTACCTACCTACCTACGTACT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa756
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000026177 Essential Splice Site 681 1264 19 33
ENSDART00000055130 None 638 1224 14 26
ENSDART00000055131 None 683 1269 17 29
ENSDART00000132175 None 746 1332 17 29

The following transcripts of ENSDARG00000015025 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 623438)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 594429
GRCz11 23 607222
KASP Assay ID:
554-0663.1 (used for ordering genotyping assays)
KASP Sequence:
TACAGGAGTGTTTCTCAGGACATCCGWCAGCTGGAGATCCACCTGCAGCC[C/A]TACAGCAAATACCACTTCCAGATCCGGGCAGTSAACAGCATAGGAACCAG
Long Flanking Sequence:
AAAGAAAAACAGTGGGCGTGGCTTGTTTTTTCTACTGCGAGCTGATTGGATGTAGTAAAGTAGGTGTTTTATTCAGAAAGATGGGGAAAAGGGTTTGGGGAGAGTTATTACCGCCTAACAGACTCCTCCTGCTCACCAATTGTTTGATTTCAAAACTGACTGCTGGAGGGGCGTGGTTAAACGTGTTAGCCCCACCCAATACCTCAGACATGCCTAATCTGAGAATTGAACTGAAACAGAAATTGAAATTACAGGAGCAAACTATTGTTTTTGTCCTAATGACATGCACAGATGAACTGTTCAGCACAAAACTAGCAATGTGAGATAACAATTTTACTATGGCTTGTTTTGATTTCATGTGTACTTTAAACACTTTATTTCTGTTGTCCTGCAGAGTATGTGATTGAGATGAACGAGGGGGAGACTCCAGACGAGGGTCAATGGCAGAAATACAGGAGTGTTTCTCAGGACATCCGACAGCTGGAGATCCACCTGCAGCC[C/A]TACAGCAAATACCACTTCCAGATCCGGGCAGTGAACAGCATAGGAACCAGTGCTCCCAGCGAGTCCTCGCTCTCCTACAGCACTCCAGCAGCCAGTAAGATGGGTTTTACAACCTTTTCTGTTTTTTTGGCAGAATATACCATTTAATTTAAGGGATTTTTAAACTTATAGGTAAAAAATCTTACTTACTAACTTACTTACAGACTTACTTACTGACTTACCTACCTACCTACCTACGTACCTACCTAACTACCTACCTATGTACTTACTTACTGACTTACCTACCTACGTATCTACCTACCTAAGTACGTACTTACTTACAGACTTACCGACCTACCTACCTATCTACATACTTACTTACTGACTTACCTACCTACGTACCTACCTACCCACCTACCTACGTACCTACCTATGTACCAACTTACCTACCTACCTACGTACTTACTTACTGACTTACCTACCTACGTATCTACCTACCTAAGTACATACTTACTTACTGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39389
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000026177 Essential Splice Site 1058 1264 29 33
ENSDART00000055130 Essential Splice Site 1018 1224 22 26
ENSDART00000055131 Essential Splice Site 1063 1269 25 29
ENSDART00000132175 Essential Splice Site 1126 1332 25 29

The following transcripts of ENSDARG00000015025 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 617518)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 588509
GRCz11 23 601302
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCAAGACAGTTCTGCAGCTAATAATATTATATTAATACTAATGTTTTCGC[A/T]GAGGGTGCTGAATGGGAAGAGTCGGAGAAGATCAACTCCACACAGGCCTT
Long Flanking Sequence:
TAAAACTTCAGTGAATAAATCAGCATTTCCAGTCAGTGTTGAACAGAAGAGCATCACCTCCTCAGCTACTCTCCAGCACAGATATCACTGAGAGAAGTGGAGTCTGCGGCACTGTGGGGATTCTCCACTGTGCTGTTTGTTCTCCTTTAATAAATAAGCTGCGCCTCAGAAAACCAACATCAAACTAAATAATCGTGGTGAATGTGGTGGCTTTTGGAGGTGTGAGATGCTTTTTGGGAGCATGTGTAACCCCGCCGGTCTTGCGCCACCCAACCCGCTCTGAGCTGGTATCGAACCAGCGACCTTCCGCATGGGAGTCAGTTGCTCTAACAAGGAGGCTAAAGACCATGGCCTCTAGCGAAGGTCACTAGAGCAGCTTTAGAGGTCAGAGGAGTGAGGTTTACCTGCACAGCACTTACTAGCTGGCCTCCGCTACACGTGCACAGATGCTCAAGACAGTTCTGCAGCTAATAATATTATATTAATACTAATGTTTTCGC[A/T]GAGGGTGCTGAATGGGAAGAGTCGGAGAAGATCAACTCCACACAGGCCTTCTATCAGCTGCAGGGTCTGGATTCAGGCGTTATTTACCATCTGCAGGTCCTGTCCGGAAACACTTCTTATGACTGGGATTTCAAAACGATATACAGGCGAGGTACGCTCTCACGCTTATTTATTTACTGTTGTGCTTGTTGGTTATGAGCAACATGTTGTAAAAGTGCTTGTCCCTGTACTATTATGTTTAATGTTTCAGATCATCAAACATATTGGGTGAAGTTTGTTTATAAACTAATGTCGAGAGGATCACGTGCTTATGATTGCTTTCAGCTGGTCCCGCATTATTCAATTTATTATTCACCAATCAGACGATTCCTAAGCCACTATGAATACCCTGAGTTCCGTATCACAGCCATCTTCATTTTAAAGAACCCCCCTCCACCCCTACGCCTTCTCCTTTCCTAGATGGGTGGCACGGTGGCCCAGTGGTTAGCATTGTTTGTTGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37581
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000026177 Essential Splice Site 1107 1264 29 33
ENSDART00000055130 Essential Splice Site 1067 1224 22 26
ENSDART00000055131 Essential Splice Site 1112 1269 25 29
ENSDART00000132175 Essential Splice Site 1175 1332 25 29

The following transcripts of ENSDARG00000015025 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 617366)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 588357
GRCz11 23 601150
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTCCGGAAACACTTCTTATGACTGGGATTTCAAAACGATATACAGGCGAG[G/A]TACGCTCTCACGCTTATTTATTTACTGTTGTGCTTGTTGGTTATGAGCAA
Long Flanking Sequence:
AATAAGCTGCGCCTCAGAAAACCAACATCAAACTAAATAATCGTGGTGAATGTGGTGGCTTTTGGAGGTGTGAGATGCTTTTTGGGAGCATGTGTAACCCCGCCGGTCTTGCGCCACCCAACCCGCTCTGAGCTGGTATCGAACCAGCGACCTTCCGCATGGGAGTCAGTTGCTCTAACAAGGAGGCTAAAGACCATGGCCTCTAGCGAAGGTCACTAGAGCAGCTTTAGAGGTCAGAGGAGTGAGGTTTACCTGCACAGCACTTACTAGCTGGCCTCCGCTACACGTGCACAGATGCTCAAGACAGTTCTGCAGCTAATAATATTATATTAATACTAATGTTTTCGCAGAGGGTGCTGAATGGGAAGAGTCGGAGAAGATCAACTCCACACAGGCCTTCTATCAGCTGCAGGGTCTGGATTCAGGCGTTATTTACCATCTGCAGGTCCTGTCCGGAAACACTTCTTATGACTGGGATTTCAAAACGATATACAGGCGAG[G/A]TACGCTCTCACGCTTATTTATTTACTGTTGTGCTTGTTGGTTATGAGCAACATGTTGTAAAAGTGCTTGTCCCTGTACTATTATGTTTAATGTTTCAGATCATCAAACATATTGGGTGAAGTTTGTTTATAAACTAATGTCGAGAGGATCACGTGCTTATGATTGCTTTCAGCTGGTCCCGCATTATTCAATTTATTATTCACCAATCAGACGATTCCTAAGCCACTATGAATACCCTGAGTTCCGTATCACAGCCATCTTCATTTTAAAGAACCCCCCTCCACCCCTACGCCTTCTCCTTTCCTAGATGGGTGGCACGGTGGCCCAGTGGTTAGCATTGTTTGTTGCCTTACAGCAAGAACGTCACTAGTTCTAGTCCTTACCAAGCCAGACGACGCTTCTGTGTTTACACGTTCTCCCCTTGCTCACCTGTGTTTCCCCCGGTTTCCTCCCACCATCCTAAAACATGCAGCTTAAGTTAATTGACTAATCCAAATCAG
Associated Phenotype:
Not determined