ZMP

tnfrsfa

Ensembl ID:

ENSDARG00000004451

ZFIN ID:

ZDB-GENE-010802-1

Description:

tumor necrosis factor receptor superfamily, member a [Source:RefSeq peptide;Acc:NP_571915]

Human Orthologues:

TNFRSF10A, TNFRSF10B, TNFRSF10C, TNFRSF10D

Human Descriptions:

tumor necrosis factor receptor superfamily, member 10a [Source:HGNC Symbol;Acc:11904]
tumor necrosis factor receptor superfamily, member 10b [Source:HGNC Symbol;Acc:11905]
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain [Sourc
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain [Source:HG

Mouse Orthologue:

Tnfrsf10b

Mouse Description:

tumor necrosis factor receptor superfamily, member 10b Gene [Source:MGI Symbol;Acc:MGI:1341090]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa7247	Missense, Nonsense	Mutation detected in F1 DNA	Not yet available
sa37265	Missense, Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa7247

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > T

Consequence:

Missense, Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000101920	Nonsense	315	435	10	12
ENSDART00000124871	Missense	317	436	8	10

Genomic Location (Zv9):

Chromosome 21 (position 14378525)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	21	16079480
GRCz11	21	16175457

KASP Assay ID:

554-4913.1 (used for ordering genotyping assays)

KASP Sequence:

CCCTCAAATCATTGGGGATTCACCGCGATCCAGCCCCCCGGCCCAGAGAC[C/T]GACYGACAGAGATCAGACTGAATCATGGCCACGGGTTAGTGAGAWKAACA

Long Flanking Sequence:

ACTTTATTTCAGAGACTGATGGCAATCTTGAGGAAGTGAAGGTTCCTATTGTAAGTATCTGTTGACTTTTTAATGTTTTAATGAGTTTTGGTTCATGATTATTTCCACTATACTGTTAAAATTAAAATAAATTTATTATTTTTTGAGCAAATTATTCATTTAATAATAATGTATTTTAAATTATTTTATTTTTAATTATTTAAACTCCTAGTTTAATTAGCTTGTTAACATTGTTCAGGATGAGTGTCCAAGATCAGAAGAGGAGCAAGAGAACAGCCGAAATGCAGGACTGGAGAAAGAGGAGGAGCACCGGCCAGAGTCCCGGCCACTCTTAACACAAGAAACACAGGAAACAGGCAGCAAGAGCATCCCAGTGGAGGATGAGGATCGAGGACTGGGAGACAGCCTGCCAAACACAACCAGCTCTTCCCAAACCAGTCTATCTGCACTCCCTCAAATCATTGGGGATTCACCGCGATCCAGCCCCCCGGCCCAGAGAC[C/T]GACCGACAGAGATCAGACTGAATCATGGCCACGGGTTAGTGAGAATAACATCTACCCCACAGTTTTCACACTGCACAATGCCTGAAACTACAGGATAGTGCTGTGAAATGTGTGGACGAATTCTTGTATGCAGATAGAAGTCTTTTTTTATTAAAAATGGTACTGGTAAATACATTCACAGCTTTACTAAGCCTAGTTTTTATTCTTCTTTTATAGGAAGACGATCCTCCCAGAAAACTCCTCCCTTTGCTCGGTAAGATATTGCTTTGTGAAACAGCATTTGTTGTTTTAACATTTAAAATTGATCTTGATCACTAGCACAATATGACAATAAAACAGTTTAAGTGGTTCAATAACTGGGTCAAAGGGCACTACAAACAAAGGCTCTGAATCATTTTAAAATTAAATGAAGTTAATTTGATTGTGGAACCGGTAAAAAAACAGATAAGATGCACTACCATTCAAAAGGTTTATGTCTTAGGAAAAAACCAAAAGCAAGG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa37265

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Missense, Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000101920	Missense	324	435	10	12
ENSDART00000124871	Nonsense	326	436	8	10

Genomic Location (Zv9):

Chromosome 21 (position 14378497)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	21	16079452
GRCz11	21	16175429

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TCCAGCCCCCCGGCCCAGAGACCGACCGACAGAGATCAGACTGAATCATG[G/A]CCACGGGTTAGTGAGAATAACATCTACCCCACAGTTTTCACACTGCACAA

Long Flanking Sequence:

TGAGGAAGTGAAGGTTCCTATTGTAAGTATCTGTTGACTTTTTAATGTTTTAATGAGTTTTGGTTCATGATTATTTCCACTATACTGTTAAAATTAAAATAAATTTATTATTTTTTGAGCAAATTATTCATTTAATAATAATGTATTTTAAATTATTTTATTTTTAATTATTTAAACTCCTAGTTTAATTAGCTTGTTAACATTGTTCAGGATGAGTGTCCAAGATCAGAAGAGGAGCAAGAGAACAGCCGAAATGCAGGACTGGAGAAAGAGGAGGAGCACCGGCCAGAGTCCCGGCCACTCTTAACACAAGAAACACAGGAAACAGGCAGCAAGAGCATCCCAGTGGAGGATGAGGATCGAGGACTGGGAGACAGCCTGCCAAACACAACCAGCTCTTCCCAAACCAGTCTATCTGCACTCCCTCAAATCATTGGGGATTCACCGCGATCCAGCCCCCCGGCCCAGAGACCGACCGACAGAGATCAGACTGAATCATG[G/A]CCACGGGTTAGTGAGAATAACATCTACCCCACAGTTTTCACACTGCACAATGCCTGAAACTACAGGATAGTGCTGTGAAATGTGTGGACGAATTCTTGTATGCAGATAGAAGTCTTTTTTTATTAAAAATGGTACTGGTAAATACATTCACAGCTTTACTAAGCCTAGTTTTTATTCTTCTTTTATAGGAAGACGATCCTCCCAGAAAACTCCTCCCTTTGCTCGGTAAGATATTGCTTTGTGAAACAGCATTTGTTGTTTTAACATTTAAAATTGATCTTGATCACTAGCACAATATGACAATAAAACAGTTTAAGTGGTTCAATAACTGGGTCAAAGGGCACTACAAACAAAGGCTCTGAATCATTTTAAAATTAAATGAAGTTAATTTGATTGTGGAACCGGTAAAAAAACAGATAAGATGCACTACCATTCAAAAGGTTTATGTCTTAGGAAAAAACCAAAAGCAAGGCATAATTTTTTCATTTTAAAAATACAAA

Associated Phenotype:

Not determined