Busch Lab

ZMP

adam10a

Ensembl ID:
ENSDARG00000053468
ZFIN ID:
ZDB-GENE-040917-2
Description:
disintegrin and metalloproteinase domain-containing protein 10 [Source:RefSeq peptide;Acc:NP_001152
Human Orthologue:
ADAM10
Human Description:
ADAM metallopeptidase domain 10 [Source:HGNC Symbol;Acc:188]
Mouse Orthologue:
Adam10
Mouse Description:
a disintegrin and metallopeptidase domain 10 Gene [Source:MGI Symbol;Acc:MGI:109548]

Alleles

There are 9 alleles of this gene:

Allele Name Consequence Status Availability
sa12400 Nonsense Available for shipment Available now
sa18489 Nonsense Available for shipment Available now
sa18021 Essential Splice Site Available for shipment Available now
sa17467 Nonsense Available for shipment Available now
sa1909 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa12400
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
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Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099639 Nonsense 29 690 1 14
ENSDART00000122259 Nonsense 101 763 3 16
ENSDART00000128654 Nonsense 95 751 6 19
Genomic Location (Zv9):
Chromosome 7 (position 31778731)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 30171073
GRCz11 7 30442223
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTGTTCACTCATAATCTGAAGGTGGAAGTTTCAGGTGTAGAGGTCCCCTA[T/A]GACACCTCTCACATTTACACTGGAGAAATATACGGTAGGCTTGGGACATT
Long Flanking Sequence:
TGTCAGTGTGTCAGTTTTTATTAGTGTGTCAAGCTTATAATGTAAAATGAATCATCCTGAACCAGTCATTCACCAGCACCTGGTATTTTCTGGAGAATCCTAATGACCTTACAGGCTGTTTGGAAATATAATAATCTGAAGGGAAGATTTAATTTGATAATAAATGCCAGAAAATAAGGGAAAAAATCTTTTTGGCAGTGAGAAATGCTGGTTGGCAGATTTCCATTATTTGCTCCCTTATCTCATAGTTCCAGTAATGCTCTGCATCATAACTCTTGGCTTAGACTATTAGTATTTTGGTGTGTTGCACAGCATCTTAAATATTGTGTCTTGTGTTTACCTCTGCTGGGACACATTGCATACATTCACAGGCAACTTCACAGTCCATTAATCTTGTTTTCTTTCTCTTCCATCAGGCATTTTAACCTTCGGATGAAGCGGGACACCTCTCTGTTCACTCATAATCTGAAGGTGGAAGTTTCAGGTGTAGAGGTCCCCTA[T/A]GACACCTCTCACATTTACACTGGAGAAATATACGGTAGGCTTGGGACATTTGCAGCACACACACACACACACACACACACACACACACTTTTGTATTTGTACACTGTTATAAATGAGATAAAGGGAATTTTTCATGTGTGGAAGAGGGCAATTAAGAAATGGCAGATATACAGTAGTGAGGTAGTCTTTTAAAAACAATGCCTTTTTAATGGGTTTATGATACAATCATATGATCCAGAGAAATTCTTCAAATGTATTCAGAAAAATAGCCATATAAATTATTCTCTGTGTTTATTGGGGACATCTGATACTGTTTTGTCGTGGCTAATGCAGTAACACAGGTGCCTCTGTAGTGTATTAGAAATATTTTGCTGTCATAAAGTAACAAAACAGTTTTATGTTGTTTAAAACAGAAAATCTATTATGATTTCTGACATTGAATTTTTGAGATCGCTACAAATGCTTGAGTTTTGGAGAAAAAATTATTTTGGGATATCGTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18489
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099639 Nonsense 185 690 5 14
ENSDART00000122259 Nonsense 258 763 7 16
ENSDART00000128654 Nonsense 252 751 10 19
Genomic Location (Zv9):
Chromosome 7 (position 31761854)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 30154196
GRCz11 7 30425346
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CGTATGTTTATAGGGTTGTTTTTNGTGCTATCCAGATTTCCAGTCATGTG[A/T]AGGCGATTAACTCCATCTATCAAGGCACAGAKTTTCAGGGCATTMGGAAT
Long Flanking Sequence:
TGACCTCACCAACTAATGCCATCATTCTGATCTCACAATGCAAACACGGAAGTCTCACCACATGGCGAGATTTCTTATTTCTCTTTGTTCTGATGTTCAGAAATCAACTTGAAGCCTGAATACATCCATAATTCATTAGAGAGAAAAAAAAGTCATTTTGTCAGTGCGCCCAAACATAGCAAATGTCTTCTCAGCCTCCTCAGCTAAATTGTAATGCATCCTGCTATTTTGTGTTCAGCAGACGAACCACATCATTGATGAAGAGGTGGCTGATGGGCCAGTGATCCTGAGGACACGTCGTGCAGCACAGGCAGAGAAAAACACCTGTCAGCTCTTCATCCAGACAGATCACCTCTTCTTTAAATACTACGGCAGTAGGGAAGCTGTAATTGCTCAGGTACACAGAAATAGCAGGTGTAGTCATGGCATATTCTGTCTACTTTTTTATATCGTATGTTTATAGGGTTGTTTTTTGTGCTATCCAGATTTCCAGTCATGTG[A/T]AGGCGATTAACTCCATCTATCAAGGCACAGATTTTCAGGGCATTAGGAATATCAGCTTTATGGTGAAGAGAATCAAAGTAAGTGTGTTTTCGTGTTTTCTCTGTGTTCATGTAGGTTTCCTCTGGGTGCTCCGGTTTCCTAAACTCCAAAGACAAGCGCTATAGGTGAATTGAATAAGCTAAATTGTCTGTAGTGTATATGTGTGAATGAGTGTATATAAAGTTTTCCAGTACTGGCTAGCAGCTGGAAGGACATCCGCTGTGTAGAACATATGCTGGATAAGTTGGCAGTTCATTCCGCTGTGGCGACCCCTGATGGGGACTAAGCCCAAAGAAAATGAATTAATGTTGTAACATTATTCGTTATGCCTGTCTGTATGTGGTTTTGTCTTTCTGTCATGCCTGTCTATGTTGTTATGTCTGTCTGTCATCATGCTTTTCTTTTTGTTGTCATGTTTGTCAATATGTTTGTATGTTATGTGTGTCATTCCTTGTTGAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18021
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099639 Essential Splice Site 326 690 7 14
ENSDART00000122259 Essential Splice Site 399 763 9 16
ENSDART00000128654 Essential Splice Site 393 751 12 19
Genomic Location (Zv9):
Chromosome 7 (position 31754448)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 30146790
GRCz11 7 30417940
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTCTCACATCACCTTCGCTCATGAAGTCGGACATAACTTCGGCTCTCCGG[T/G]GAGTYCTTTTCACTATATGTGCTGCATCCTAGACACATTAGYCGTAAASA
Long Flanking Sequence:
AAAAAATAAATAAAAAATAGAGCTGTTTGACAGAGCTGCAGCATTAATAATTTTGATGAATTATAGCTGGCTCTGCACATTCAATTAGGATAGAAGTTTGGCTTTTAAGATTTGACACTTTAATTCGTTTGAATGTCTTAGCTTGGATGTTTGTATAAATGTTTCATTTTAGTTCACAAGTAGAGCAAAAGAGCGTATTTTGTGCATTGTTTTGTTTTAATGACTTTTAAATTTGTTTCTGAACTTTTTGTTTTGTCATTTTTTAGTTAATATAGTTAATGTTTTTAATTTTATATTTTGTATTTGATTAATGCCTTTCTATTGTGTCATTTCAGGCAGCTCCGGTGGAATCTGTGAGAAGAATAAACAGTACTCTGATGGGAAAAAGAAGTCTCTGAACACCGGCATCATCACAGTGCAAAACTATGCATCACACGTTCCTCCTAAAGTCTCTCACATCACCTTCGCTCATGAAGTCGGACATAACTTCGGCTCTCCGG[T/G]GAGTCCTTTTCACTATATGTGCTGCATCCTAGACACATTAGCCGTAAACAACACACCTTAGCTGAATCCTTTATGAACAAATCAATTTTACTCTTCGATGCTTCGCGAAATTAGAAATTGCACACTATTGCCTTTGAGACCTCAAATTGTCAGATTGATCTAGCCAAGCTTTTATAATAACCTGACTTGGTATTCACTCTATCCTCAGTTCAGTTTAAAAGCTAATGCCGAGAACTGGCCGATGGCCAACTAAAAACAGTGTTGGAATATTTTCAGGATGAATTATAGCAGCAGGCTAATTAAGATCTTGTTATATAATTTTTATATATATATATATATATATATATATATATATATATATATATATATATATATTTATTGTGTGTGTGTCTGTGTGTGTCTGTGTGTGTCTGTGTGTGTGTGTGTCTGTGTGTGTGTCTGTGTGTGTGTGTGTGCACACAAGCAGTTTTTTTTAATCTTCCATTCAGGCCACACTAGTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17467
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099639 Nonsense 455 690 10 14
ENSDART00000122259 Nonsense 528 763 12 16
ENSDART00000128654 Nonsense 516 751 15 19
Genomic Location (Zv9):
Chromosome 7 (position 31751956)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 30144298
GRCz11 7 30415448
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AATCTTTTCTTTTGCAGTCCCAGTCAGGGTCCATGCTGCACACCACAGTG[C/A]ACGTATAGGACCGGTAAKGAATGTAGGCCGGAATCAGACTGTGCATTTAA
Long Flanking Sequence:
TAAATAATTAAACCCCTGTTCTGTAGAATCTTATATCCTTGTGACAGTTTGCTTAACACTCATTTGTGACTGACAGACTCTGCAGTAATTTATTATTAAAGAGTTAGTTTGCCCCCAAGAAAAAATTTTATCGTTTACCTACCCTCATGTCATTTTAAACCCATAAGACATTTGTTCATCTTTAGAACACAGCTTAAGACATTTTAAATGAAATCCAAGAGATCAGAAACTAAATTATGAATTAAGCAGTTTATTTAAAGCTTTCTGAAGAGGCATAATTGCTTCACATGTTGAATGGATTTTAGGATTTATATCTTTCTAACTTTTTCTGTCCCGAGTAAATGATAGAATTCAGCGGATAAATGAAATGATCGTAATGTTTTAATGGGGTGAACTAACCCTTTGAGTGAACACATTTTTCATTGAGAGAAATAAAGTCTTCATTTTTTCAATCTTTTCTTTTGCAGTCCCAGTCAGGGTCCATGCTGCACACCACAGTG[C/A]ACGTATAGGACCGGTAATGAATGTAGGCCGGAATCAGACTGTGCATTTAAGGGCTTGTGCAATGGACTCTCTGCCCAATGCCCTGCCTCAACACCCAAAGAAAACTATACAGCCTGCCATGCAAATACACAAGTCTGCATTAATGGGGTAGGTGATGCATTATGGCCTGTGTCAGAAAATGTATCACATGGTCATAGTCCAGCAAGTCAATGGCAAGATTTATCAAGCTGAAACTGTGAAAGAAGGAGTAGACTATACACAGTGATTTGCCCCTCAGGCTTGAATAATAATCATTATTAGCTTTAATTATGATGTGTATTTTAAGGTTTCCTTTGGTGGTTTGGATTTTGAAAGATGTTATACATACATTGAAAGTGAAGGACTTTTATATATTATTTGTCTATTTCATGTTTATCATTAAATAATTTAACTTCTCATTTTTTAAAATCTTTTTTTATACCCTATTTTTAACACATTGTTTTTTGGCGATATTTGCAGCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1909
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099639 Nonsense 475 690 10 14
ENSDART00000122259 Nonsense 548 763 12 16
ENSDART00000128654 Nonsense 536 751 15 19
Genomic Location (Zv9):
Chromosome 7 (position 31751896)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 30144238
GRCz11 7 30415388
KASP Assay ID:
554-1899.1 (used for ordering genotyping assays)
KASP Sequence:
ACCGGTAATGAATGTAGGCCGGAATCAGACTGTGCATTTAAGGGCTTGTG[C/A]AATGGACTCTCTGCCCAATGCCCTGCCTCAACACCCAAAGAAAACTATAC
Long Flanking Sequence:
CATTTGTGACTGACAGACTCTGCAGTAATTTATTATTAAAGAGTTAGTTTGCCCCCAAGAAAAAATTTTATCGTTTACCTACCCTCATGTCATTTTAAACCCATAAGACATTTGTTCATCTTTAGAACACAGCTTAAGACATTTTAAATGAAATCCAAGAGATCAGAAACTAAATTATGAATTAAGCAGTTTATTTAAAGCTTTCTGAAGAGGCATAATTGCTTCACATGTTGAATGGATTTTAGGATTTATATCTTTCTAACTTTTTCTGTCCCGAGTAAATGATAGAATTCAGCGGATAAATGAAATGATCGTAATGTTTTAATGGGGTGAACTAACCCTTTGAGTGAACACATTTTTCATTGAGAGAAATAAAGTCTTCATTTTTTCAATCTTTTCTTTTGCAGTCCCAGTCAGGGTCCATGCTGCACACCACAGTGCACGTATAGGACCGGTAATGAATGTAGGCCGGAATCAGACTGTGCATTTAAGGGCTTGTG[C/A]AATGGACTCTCTGCCCAATGCCCTGCCTCAACACCCAAAGAAAACTATACAGCCTGCCATGCAAATACACAAGTCTGCATTAATGGGGTAGGTGATGCATTATGGCCTGTGTCAGAAAATGTATCACATGGTCATAGTCCAGCAAGTCAATGGCAAGATTTATCAAGCTGAAACTGTGAAAGAAGGAGTAGACTATACACAGTGATTTGCCCCTCAGGCTTGAATAATAATCATTATTAGCTTTAATTATGATGTGTATTTTAAGGTTTCCTTTGGTGGTTTGGATTTTGAAAGATGTTATACATACATTGAAAGTGAAGGACTTTTATATATTATTTGTCTATTTCATGTTTATCATTAAATAATTTAACTTCTCATTTTTTAAAATCTTTTTTTATACCCTATTTTTAACACATTGTTTTTTGGCGATATTTGCAGCAAGAACCTTAAGAGCCATTGCTCTCTGTAATTTGTAAAAAGGGGACTATGAGGGAAATAAA
Associated Phenotype:
Not determined