Busch Lab

ZMP

camkk1

Ensembl ID:
ENSDARG00000035452
ZFIN ID:
ZDB-GENE-050327-62
Description:
calcium/calmodulin-dependent protein kinase kinase 1 [Source:RefSeq peptide;Acc:NP_001014361]
Human Orthologue:
CAMKK1
Human Description:
calcium/calmodulin-dependent protein kinase kinase 1, alpha [Source:HGNC Symbol;Acc:1469]
Mouse Orthologue:
Camkk1
Mouse Description:
calcium/calmodulin-dependent protein kinase kinase 1, alpha Gene [Source:MGI Symbol;Acc:MGI:1891766]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa40469 Splice Site, Nonsense Mutation detected in F1 DNA Not yet available
sa6985 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa20454 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa40469
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Splice Site, Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000028237 Splice Site, Nonsense 279 434 11 15
ENSDART00000133743 Splice Site, Nonsense 326 481 13 17
Genomic Location (Zv9):
Chromosome 5 (position 33050920)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 30813152
GRCz11 5 31413305
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACTCATCCGTCTGTCTTCTTTTTTTATTTCTCTTCCTCGTCCTCCAGTG[C/A]CCATTTATTGATGAGTACATACTGGCTCTTCACAATAAGATCAAGAGTAA
Long Flanking Sequence:
CTGCTCTTTAATGTTTATTTGCTACCCATCAGAGAAAGACTTAAAATACGGGAAAATATCTTTACGGGATGATAACCGGATAGAACTGTGAAAAACGGGAGAATCCCAGGAAAAACAGGAGGGTTGACAGATATGCAACGTTCACACTAGCTAAACCTACAGAACTCTGACATCAAATGAACCCGGTTGTGGACCAAGCTAGTGTAAATGCAACCTAAAACTGTCCTACATCACTATAACAGAAGTTGTGTTCTGTTTAGGCTCTGGACGTGTGGGCAATGGGAGTGACCCTCTACTGTTTCGTCTATGGGAAGGTGAGTTTCCTCTTGCGCTGATATGATCAGAGTGATAGCAGTAATTCTTCATTGTGGGATTATATATCAGAATGATCAATGGACGGGCTGCCGCTGCTGCTGCTGCGGTGACATTTGTGTGATTGATGATTTAGATCACTCATCCGTCTGTCTTCTTTTTTTATTTCTCTTCCTCGTCCTCCAGTG[C/A]CCATTTATTGATGAGTACATACTGGCTCTTCACAATAAGATCAAGAGTAAAGTGGTGGAGTTCCCCGACACGTAAGTCACCCCACAGGAACAGATGCAGAGAAAGGAAATGTCAGAGATGTTTGAGTGCAGCGAATGTAAAGCTGATTCATGTTGGTTTATGCAGGATATTTGTGTATGCTTGTGCAGGTCTGTTTAAATGATGTGCTGATGAAGTGTGTGAAAGACCAGAGGGCATCCGGATGCATGTCATCTGGTGCCTGTGTTTGGAGTCATCAGCTAATAAAAGAGCAACTTGTCTATCTTACACACACACACACACACACACACACATACACAAACAAACACACACACACACACACACACTGCTCCTTGTTGTGTTCTCAGTGGCTGAACTAACTGAAACATATCACAGTGTCAGTGGCTCTCAGTAAAATAGTGTCTACATGACTAGGGGCTCTCAGTATTTTTGCCAGCAGAACCCTTCAGTATATTTTAGGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6985
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000028237 Essential Splice Site 303 434 11 15
ENSDART00000133743 Essential Splice Site 350 481 13 17
Genomic Location (Zv9):
Chromosome 5 (position 33050992)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 30813224
GRCz11 5 31413377
KASP Assay ID:
554-4606.1 (used for ordering genotyping assays)
KASP Sequence:
CTGGCTCTTCACAATAAGATCAAGAGTAAAGTGGTGGAGTTCCCCGACAC[G/A]TAAGKCACCCCACAGGAACAGATGCAGAGARAGGAAATGTCAGAGATGTT
Long Flanking Sequence:
TAACCGGATAGAACTGTGAAAAACGGGAGAATCCCAGGAAAAACAGGAGGGTTGACAGATATGCAACGTTCACACTAGCTAAACCTACAGAACTCTGACATCAAATGAACCCGGTTGTGGACCAAGCTAGTGTAAATGCAACCTAAAACTGTCCTACATCACTATAACAGAAGTTGTGTTCTGTTTAGGCTCTGGACGTGTGGGCAATGGGAGTGACCCTCTACTGTTTCGTCTATGGGAAGGTGAGTTTCCTCTTGCGCTGATATGATCAGAGTGATAGCAGTAATTCTTCATTGTGGGATTATATATCAGAATGATCAATGGACGGGCTGCCGCTGCTGCTGCTGCGGTGACATTTGTGTGATTGATGATTTAGATCACTCATCCGTCTGTCTTCTTTTTTTATTTCTCTTCCTCGTCCTCCAGTGCCCATTTATTGATGAGTACATACTGGCTCTTCACAATAAGATCAAGAGTAAAGTGGTGGAGTTCCCCGACAC[G/A]TAAGTCACCCCACAGGAACAGATGCAGAGAAAGGAAATGTCAGAGATGTTTGAGTGCAGCGAATGTAAAGCTGATTCATGTTGGTTTATGCAGGATATTTGTGTATGCTTGTGCAGGTCTGTTTAAATGATGTGCTGATGAAGTGTGTGAAAGACCAGAGGGCATCCGGATGCATGTCATCTGGTGCCTGTGTTTGGAGTCATCAGCTAATAAAAGAGCAACTTGTCTATCTTACACACACACACACACACACACACACATACACAAACAAACACACACACACACACACACACTGCTCCTTGTTGTGTTCTCAGTGGCTGAACTAACTGAAACATATCACAGTGTCAGTGGCTCTCAGTAAAATAGTGTCTACATGACTAGGGGCTCTCAGTATTTTTGCCAGCAGAACCCTTCAGTATATTTTAGGTTTTTCAATTATCAGATTTTTTATATTAGTAGAATGTGATTTATATCATATGCTGTGTACACTATCATTTATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20454
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000028237 Nonsense 316 434 12 15
ENSDART00000133743 Nonsense 363 481 14 17
Genomic Location (Zv9):
Chromosome 5 (position 33055587)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 30817819
GRCz11 5 31417972
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTGATATCTTAGACCGACTGTCAGCGAGGGGCTGAAGAGCCTGGTCTCA[C/T]GAATGCTGGACAAAAACCCAGACACCAGGATCACCATTCCTGAGATCAAA
Long Flanking Sequence:
TTTAGACTATACAGGTAATAAATGTTTTCTTTTAACAAATGCTGAAATTATGTTATTTGAAAAAGATACAACACATGGTGGTTTTGTGAATGCTATGCTTGTGTATATGAACCATGTGATCACTGATTTGTGCATAATTTTACTGTGTTGCTGCAGAATTTGGCATTACAATGTGGTGTAAATTATGCAAAAGCAGTGCAAGGAGCAGGGGTTCATAACCCGTTTGTGGTAAACATTCCTATACAGTACCTGGGGTTACTTGCAGAGTTTTTCAGTGCAGTTTGAAGTTCAGCTTGTTTAGTGGTCTACAGCTCTCATGAAGCATTCTGAATCAGTTTTGGGGTTAACATTGAAATTCCTATGCCTCCAGTGAGTCTCATGCCTTATAAAAATGTGCTGTTGTTGTTCTGATATAGTTTTTTACCACTTCAGCTGTTTGTTCTGTGTTTTTGTGATATCTTAGACCGACTGTCAGCGAGGGGCTGAAGAGCCTGGTCTCA[C/T]GAATGCTGGACAAAAACCCAGACACCAGGATCACCATTCCTGAGATCAAAGTAAGTCTACACAAGGCGCATTTCTGAAATCCAGAGTGGCAAGTAATCCGTTTTACGTTCATCCTCACAAATCTGTATTGCAAGATATTTTAAAGACTAGAGTATATCTTCTTACACACAAAAATATGTTTGCATTTGGCCTTTTCGGCAGACTTAGCATTATTAATTTGTGCATTTTCCTTCAGAAATTCTTTGTTTTCTTCTATACTGGCAAGACAGTATATCCTCTTTAAATATTGAAATTATAGTCAGCATCTTTAAAAGAAATATACCAAGAACATTCCAGAGAGTAAGTCTCATTAGTTTTCTCTCACAATACCAGCCCTGTTTTTATCATGGAGACACATTCAGGCATGTTGTTGAAATATGACACAGTACCTTTGATAGCTTCTGCTTTATCAAGCTGACTTGAAATTTGGATAGAAACACATCAGCTTATCCCAATGGAGA
Associated Phenotype:
Not determined