Busch Lab

ZMP

plxnb2a

Ensembl ID:
ENSDARG00000003811
ZFIN ID:
ZDB-GENE-030131-8917
Description:
plexin-B2 [Source:RefSeq peptide;Acc:NP_001155072]
Human Orthologue:
PLXNB2
Human Description:
plexin B2 [Source:HGNC Symbol;Acc:9104]
Mouse Orthologue:
Plxnb2
Mouse Description:
plexin B2 Gene [Source:MGI Symbol;Acc:MGI:2154239]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa6934 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa6933 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa20240 Essential Splice Site Available for shipment Available now
sa17574 Essential Splice Site Available for shipment Available now
sa839 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa6934
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000048821 Essential Splice Site 481 1864 3 35
ENSDART00000143773 None None 917 None 21

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 4 (position 13550424)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 14486277
GRCz11 4 14485032
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTTGTTTGATTCAACTTTGAATCACCTGTACATCACCACTGGCAAAAAG[G/A]TTTGCTTATGAACACATTMAYAATGTATAGRTAACGTTWKGTCAACAGGA
Long Flanking Sequence:
TCAAACCTATCTACACCAGGAATGACATGCTGACAGCTGTAGCTGTGGCGGTGGAGAACGAACACACTGTGGCATTCTTGGGAACCAGTGGTGCAGACGTCTTGAAGGTGAGTCCCATTGCAAGGTCTGCTTTCTGTTCTTTAAATTTCACTTAAGCCCTTGTGGTTTGACTGGCTGTGGTGGTAGGAACTAGTGGTTAAAGATATGGGCTGGTAACCAAAAGGTTGTCATTTCAAACCCCAGAATTTATGATTTATGAGGTACAGTATAACCACTTTAGCAGTGCGTTCTACTCTAGGACTTGATCTTGCTGTACACAGTATTGGTTTTTACTTGTGTGCGAAATAAATTAACTAACTTTTTCCTTGCAGGTGCATCTTGACCCAAACCACACTGACTTTTACAACAGAATTCCAGGGGATCGTGCAGATGGTGCAGTAAACAAAAACCTTTTGTTTGATTCAACTTTGAATCACCTGTACATCACCACTGGCAAAAAG[G/A]TTTGCTTATGAACACATTCACAATGTATAGATAACGTTAGGTCAACAGGATCACCCATTGGTTAATATTTATTTGAGAAATGTAGACCTGACAAGCTCAATGGATTTCTTTTCTTTTTTTTTTTTTTGCAAAATAGCACAAATGCCTAGATATTTCACACAGCTCTGTAAAATCCTTAGACGCTGTAATCTGCCACATAAATGTGATAGCAGACTGTTGTCATATTCTTTTCACCAACCACAAGACTTTGAGGTGCTCTCGTCCTGTCAATCATTTTACACAATTACACAACGGCTGTATTAGAAGCAGGACTATGATACGGTAGTTAAAGTAGATGCCACAAGCTCCTTCATAAGCAGTGTTAGTTTTCATACACATATTTGATTTTACGAACCAATGTTTCTTAGGCTACATGCACATGACTACAGTGTAGTCAAAAATACTGTCACCTTGTTAGTAGAACAGTACCTGTTTAGGTGTAATGACTAATATGCATTTTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6933
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000048821 Essential Splice Site 782 1864 11 35
ENSDART00000143773 None None 917 None 21
Genomic Location (Zv9):
Chromosome 4 (position 13541407)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 14477260
GRCz11 4 14476015
KASP Assay ID:
554-5200.1 (used for ordering genotyping assays)
KASP Sequence:
TACATAAAGGATAAAGACACGGATAGGAAGATTGACAGCACCCTGAGAGG[T/C]ACATTTAAATGAGTTGTTCTCAGAGCYAAGAAAGCAAATCTTCAAGATCA
Long Flanking Sequence:
CAAAACCTTTCAGATCGGCACCGAGCTCATGAAGCAGGTGGGCGAAGTGACTGTGGAGGCCGATGGGTTAAAGTACAGATTTGAGGGATATGAGGTCAGTACATTACACTCCTCTATTACCTCCTTCTCTGTCATTGATTTGTTTCTGGAAGTTTGAGCACCAGCCAATATAATGGCATTCAGCGTTATTGAGCCGCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGGAGGGGTTTAGTCCTGTGTGGGTGTAGAAAACACATAGCCATCAGGTTCACAAAGACATCATGTTGGCAGGGGAGAATTTGCGACGACACACAGTTGTTCCGTGTGTTTTTGTGCATGTTTAATGACACGTTTTCTTCTGCTTCATGCCAGTTTGCGTATGACAAAGAGCCAGAGGTGAATGTGACGTTCTACATAAAGGATAAAGACACGGATAGGAAGATTGACAGCACCCTGAGAGG[T/C]ACATTTAAATGAGTTGTTCTCAGAGCCAAGAAAGCAAATCTTCAAGATCAGGAAAAGACTGTGTGTGAATATCTGATGAATATGTTAAAATAAGGAGATTAGCATATGTTTTGTATTATTATTAACATATTGTTCTCATGAATCTTGTTTTTGTATCTGACTAGAGGTGTTTTAGGTGTTTAGCCAATGAGCCTCTTTTAAAATTATTAGTTTATTTTAGATGGAGACAATGAATATCAGGGTAATTATTGAAAAAATTATCAAATTGGAAAATAAATGTTTTGGTACACTGTAAAAAAATATGAGTTAAAGGTCATGCCAACATGTTTTTATGGTATACTTTTTTTTACAAAATGGTTAATCATTTTTCAGCTCCTTATTTTTTCTCTGAGTAAGTAAACAATTGTTTGTAAAATTAATTTGTTTCAACTTATTAAAAAAAATATTTAAAATATATTTAAAAAAATGTAGATTAAAAGGGCTAATAATTTTGACCCTAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20240
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000048821 Essential Splice Site 782 1864 12 35
ENSDART00000143773 None None 917 None 21
Genomic Location (Zv9):
Chromosome 4 (position 13540021)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 14475874
GRCz11 4 14474629
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GATGATGAATTCAGTGTCAGTTCTGTGAATAGTTTTCTTTTCTTTTCCCA[G/T]TGGTTCTCTACAACTGTTCGGTTAGACGCGAGGACTGCAGTCTGTGTAAA
Long Flanking Sequence:
AACGTGACTTTTCCAAACGCTGTATGTCTTGAAAATGGTTCTCATCCCATGCCTGCTGTGAATGTTTATTTGTTACTACTATACAACTATACTTCAATACAATATTTTTTGTCAGTTTAATATAATGAAAATACAAAAAGCTAATTTTTTTAGCAACTAATTTTCCATAGTGTACTTATTACTGTGTATTTGTCAGACTTTATAATCTGAACAATGCCACAAAAACTGTGTTGATCTCAGTTAGACAGTTTAGTGACAGCATCAACAAAAATGCAATCTTTGCACCACAGTAAATGTGACTAATAAATCAAACAACAATAAACAGACAAAATGTGCATAACGTATCATTTCTGAAAACACCGTGATAAACTGCAGTGTTTAATGAAATGTTTATTTCTCCACAAAGCAAAAAAAGACTCCGGGAACTTTTTGAAGTTGTACTTTGTTGAAGATGATGAATTCAGTGTCAGTTCTGTGAATAGTTTTCTTTTCTTTTCCCA[G/T]TGGTTCTCTACAACTGTTCGGTTAGACGCGAGGACTGCAGTCTGTGTAAAAATGCACACAAGAATGATAGCTGCGTTTGGTGCGACACTACAAAATCCTGCATCTACAGAAGCCTGTGTGACAATGAACTGCACCAGTGTCCTCCTCCAAAGATCACAGACGTAAGTGTTTTAGAAGTGCCCTTGGTATGCTATCTTAGCTTAGGTACTCATCTGCTATTGACCTTATGCTAAAATGCGGAAGTGCGCCTGTTTTCGCGATTGTCTTAGAACTTCCGATTCAGTCACCTATGGGAGAAATGACTAGGAATAATAAACGGCAGAAAATGGTCAAACTACTTGCTCTACAAACAAATGATTGCATGACTATACAGACCAAGTAGAATAATATAATAAGAAAATATCAAATTGCAACATCAAGCAGCGTAACTTGCAGTTTTTAACGTCAAAAAATGAATGGAAGTGAATGAGATCAGAAGTCTCGAGCTAAAAAGATTCAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17574
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000048821 Essential Splice Site 1281 1864 21 35
ENSDART00000143773 Essential Splice Site 334 917 7 21
Genomic Location (Zv9):
Chromosome 4 (position 13529120)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 14464973
GRCz11 4 14463728
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GGCCAATTTGGAGGAGAGYGTCCGTGATCGCTGTAAAAAGGAGTTCACAG[G/A]TGAGATCCTAAACTTTTCATATCTGTAGGCTTTTTCTTNCTCAAATAGTTC
Long Flanking Sequence:
TACTAATGTTTTTATTTCAGAAGAATACGGAACTGATTTTTCAGTCGAGAAGTGAAGCTATTCGTTATTCTGACCAATTTTTACTTTTGGAAAGAATAAAAATGCTTCAAAATTTACTTAATTTGTATTTGAAAGTCTTTTTAATGAAACAAATATTAAAATTTTACTCAAAGCTATTCCTATAAACTTTTTTTTTTATTTACATAGCTGTATTCCTGTTCGATTACAAAGAAATGAAGCTGTTTTAATGCATTATTAATAAATAATAACCCATATATTTAGAGTAAACTGAGGAGGTGAAAAATTACTTTGATTCACAGCCACAAGTTTTTCAAAATAATACACTTTAAATTAGACATTGAGTAAATGAAGATTAATGTTTATGTTTTCATTTGTCAGGAGGAAAAGCCAGCAGGCAGAACGAGAATATGAGAAGATCAAAAATCAGCTGGCCAATTTGGAGGAGAGCGTCCGTGATCGCTGTAAAAAGGAGTTCACAG[G/A]TGAGATCCTAAACTTTTCATATCTGTAGGCTTTTTCTTCTCAAATAGTTCAGTTTTATTAAAAAATCTTGAGAGCTTTTTGTGATATAAACTTGTTTTTCTGACTTGTTTCTTTGCCTAATATTAGCTTTTTAGAAGAACAGCCAATATTTTCAACCAAGCTTCAATTTATGTACAGTATTGCACAATTGTCTGTTTTCATAGATCTAATGATAGAGATGGAGGATCACACCAGTGATCTGAGTGAAGCTCGCATCCCATTCCTGGACTACAAGAACTACACCGACCGTGTTTTCTTCCTGCCCTCGAAAGATGGAGCCAATGATGTCATGATCACCGGCAAGCTGGATATCCCTGAAAACCGCAGAGCCATCGTAGATCAGGCACTCAACCAGTTCTCCAACCTCCTGAACAGCAAAACCTTCCTTATCAATGTGAGAAACTTTACATAGAATAGTGATGCTTTGATGTTGATTTATTTATTTTTTTACAAGCAAATTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa839
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000048821 Essential Splice Site 1758 1864 31 35
ENSDART00000143773 Essential Splice Site 811 917 17 21
Genomic Location (Zv9):
Chromosome 4 (position 13517729)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 14453582
GRCz11 4 14452337
KASP Assay ID:
554-0742.1 (used for ordering genotyping assays)
KASP Sequence:
TCAGACCTTCATGGACGCCTGCACTAAAACCGAGCACAAACTGACGCGGG[T/C]GAACAGAAACACTTCATCATTCATCAGCTTCATCAAAACCCTCTCTTCAT
Long Flanking Sequence:
TTTACAATTATCATTAAAAAATATATTATAAATAAATAAAAATAATCCTTTTGATATTATTATTTTTGTTTTGTTTTTACCATTAGTTGATGATGATAATGATTCTTTTCAGATAGATAGATAGATAAATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATTGATCCCTCTCCTTGTAAATCAATTTGTCAATCGTTTGATTTGTATTATTTTAATTAGTATTTTTTCATACATCTGTGTATGTTTTTGTTCAGTCTTCCTCTCCGTTTCTGGGTGAACATCTTGAAGAATCCTCACTTCATCTTCGATGTTCACCTGACTGAGGTAGTGGACGCATCTCTGTCCGTCATCGCTCAGACCTTCATGGACGCCTGCACTAAAACCGAGCACAAACTGACGCGGG[T/C]GAACAGAAACACTTCATCATTCATCAGCTTCATCAAAACCCTCTCTTCATCTTCTCTTTCAGTCTCATGCTTTCTCTCCTTGATGTCTTGTTTTATAGGAGTCTCCCAGTAACAAACTGCTTTATGCAAAGGAAATCTCCACGTACAAGAAGATGGTTGATGAGTAGGTTTTTATTGTTGTGTAGGTTTTTATTATTTGGTGTTATTACAGTAAACTAAGCAGTGATGTTTTCTGTGCTCTTCAGTTATTATAAAGGCATTCGGCAGATGGTTCCAGTCAGTGACCAAGACATGAACACACACCTCGCAGAGATTTCACGGGTATGTGAAATTTTTTTTTTTTTAATTTCATGTGAATTTTGAAATTTTCTTTCGATTTTTAATTGTTTTAGTGCATTTTTATTTTGTTTTATTCACCTGAATTTTATTTTAATTTGCATTTGTTTACCCTATTTGATTACAATTTATTTCATTTGACTTATTTTAATTTTGGACTCACT
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461