Busch Lab

ZMP

si:ch211-284o19.1

Ensembl ID:
ENSDARG00000038713
ZFIN ID:
ZDB-GENE-070912-283
Human Orthologue:
TEP1
Human Description:
telomerase-associated protein 1 [Source:HGNC Symbol;Acc:11726]
Mouse Orthologue:
Tep1
Mouse Description:
telomerase associated protein 1 Gene [Source:MGI Symbol;Acc:MGI:109573]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa38344 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa6856 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa32973 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa32974 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa38344
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000056536 Essential Splice Site 287 1036 3 19
ENSDART00000141784 Essential Splice Site 287 561 4 11
Genomic Location (Zv9):
Chromosome 2 (position 37641637)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 37920769
GRCz11 2 37903226
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAACTAGCTACCGAGATTACCACAGAAGATCCTGAGTTTGTCCTCAAGG[T/C]TTGTGCATTTGCGTGTGTGAGTGTATGCTTGTTGTGATTTTTGTAGTTGA
Long Flanking Sequence:
CTGTGGAACGAACCGCCAACTATTCCAGCATATGTTTTGCAGAGTAGATGCCCTTTCAACCGCAACCCAGTACACAGTCATACACTATGGCCAATTTAGTTCATCCAATTCACCTATATCGCATGTTTTTATGCTGAACATGGGGAGAACATGCAAACTCCACACAGAAATTCCAACTTGCCAAGCCCGGACTCGAACCAGTGACCTTCTTGCTGTGAGGAGACAGTGCTAACCTCTGAGCCACAATGCTACCCTTTTAATAATTTAAATAATAATAATAAATAATTACTTCAATCATTATTCTGCCAGATAATGGATGTTGTTTTTGTTGTTTTTGCAAATCCTTCAGAACAACCTGTTGAATATGGTGTGCTGCTCGCTGATTCAGAAGGGCTGTGCCCCAGGCCAGAAGGACTGGGATAACAAGAAGAGTGTGTGGAGCATTATCAAGAAACTAGCTACCGAGATTACCACAGAAGATCCTGAGTTTGTCCTCAAGG[T/C]TTGTGCATTTGCGTGTGTGAGTGTATGCTTGTTGTGATTTTTGTAGTTGATGCTAATGATTTTATATTTGCATTGGTTTTAGGTTGCAGTCTACACTAGGCAGGAACTGAACATTCGTATCACAGCCAACTACCTGCTGGCGTTGGCTGCTCATCTGCCTGCGTCTAAACAACACCTGAGAAGATACTTTTGTCCTGCTGTGCAGCTGCCATCTGATTGGCTGGAAGTGGCACGTCTCTATAGCATGGTATGTTCGCCTGTCATATGATATTTACACGGTATTATATATCATATTGGCTCTTCAAGGTATTTCAAAGAATATTAGCACTGTAGATTTACAAATAAGGTCTTTATTTTTCTTGTGTGGTATTATTTCAATGTTGTTTTGCTTTTTTCCTGCTCTTTCAGTGTTTCAGTAAATCTTTACCCTCTTGCCTGAAAAAAGCTCTTGTGGATAAATTTAAGCAGTTCAGCGAATATCAGCTGGCTAAATACAATAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6856
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000056536 Essential Splice Site 542 1036 9 19
ENSDART00000141784 Essential Splice Site 538 561 10 11
Genomic Location (Zv9):
Chromosome 2 (position 37644366)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 37923498
GRCz11 2 37905955
KASP Assay ID:
554-4388.1 (used for ordering genotyping assays)
KASP Sequence:
GCATCAGCGAGAAACATCACTCTAAGATTCTTAACAGACTGTCCTCGAAG[G/A]TGAGCTAGATTTCTTTCAKTCTTTTGCTCACYGAAAAGTGTGCGTGTATG
Long Flanking Sequence:
ACTGTGGATGGGTGTAAACGTATCGTAGGAGGGTGTAAAACAAAATTAAAAACCTTAAGAAAAGCAAAATGGGGACACTTTAATATGTTTTACATTGGTTAACTGCTATCTTCAACTTTCTATTTTTTTATGTATTTTTTTTTTATTCTGCAGATACCCGAGTGATCTGAAGGCGTTCTCTCGCAGTGGTCTTAGTGGGGTCTGGGACAGAGAGAGAGCCGGAAAGCAGATGAAACTTAAGCAACCTGACACATGGGAGCGCAAAGTTAGTCAGGAGGGAAACAAAGCTGCCACCTGGGAGAAACTCATCGGTGTGTGAAGGAGGGACATACTGCATCTGAAACGGACATTATTTTTGAACGTCTACTTATTTAGGTTTTTAATTTGCAGATGGGAAGTCTCTTCCTTTTATGGCCATGCTCAGGAACCTGAGGAACATGATCACTGTGGGCATCAGCGAGAAACATCACTCTAAGATTCTTAACAGACTGTCCTCGAAG[G/A]TGAGCTAGATTTCTTTCATTCTTTTGCTCACCGAAAAGTGTGCGTGTATGTGTATACAGTATTATTTCATTTTTGAGTCTGAATTTTTCTTACAGAATGCTGTAATCCAGAGCAGGCAGTTTCCCTTCCGCTTCCTGTCTGCTTATAAAGTCATTTTGGAGCTCTTTAAGTTTGGTAAGTTCCTGATTTTAAAGGGCATTCAATTTAAGAGTTGGGTCCAGATGAATGCAAAAACCCAAGCTGTAAAAACTGAGTGCAAAACTTTGAGACCCTCATACATGCTTTATTTAAAATGAATATGTTCTATTGCTTTATTGCATTGTGTGTTCATGGAGGGCATTACTTTTTATGTGCAGAAGCCCTTTGCTGGAGATTAGGAAAATAATGTTGCAGACACCATTAGCAAATCCATGATTATACTATCAATACAGTTTTACTTGCATTAATTAGGGAGGCAGTAATAAAAAGTAATTATTAATATGTAACTAAATAAATTAAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32973
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000056536 Essential Splice Site 635 1036 11 19
ENSDART00000141784 None None 561 None 11
Genomic Location (Zv9):
Chromosome 2 (position 37646608)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 37925740
GRCz11 2 37908197
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGTCTACCGCCTGTTCAACGTCAAACGCAGTCTCATGATAAAAGCAAAG[T/C]GTGTATTGCTCAATATTTTGTTTAAAAAAACTTTACCATAGTTTAAAGGT
Long Flanking Sequence:
TTGCGCCATGCTCTTTAGACTTTGCACCTAGATCAATAAAATAGGGCCTAAACTATGTAAAGCGAGCTATTTCCACCTTTATTTTTTTATCATATTAATGTATCTTTTGGTTAACACAAATTATTAAAAAACAGATACCCCAAACCTTTGTACAGTTGTGTATATTTAACTCGTACATTAGGTTTAAGTGTTTTAATCTACAAAACTGTTTATTATTGAAACAGCACATTTCCATAGAAACTTTTTATATTTTTATAGATGTGCTCTTGATGTTTGAGTGACATGTTTTCCCTCTTTCAGCCAGAGGAGCTGCGGTAAAAACGAAGAGCTCTACGGACATCATTCGAGACATTCTAAAGAAACTGCCAAAGACCAGACGATACAACCGAAACTGCTTGGACTGGGATAAAGCAGAACGCAAGAAACTGCGGGTTACATTGCGTGTGCCCTTTGTCTACCGCCTGTTCAACGTCAAACGCAGTCTCATGATAAAAGCAAAG[T/C]GTGTATTGCTCAATATTTTGTTTAAAAAAACTTTACCATAGTTTAAAGGTGCTTTATGTAAGTTTTTAACTGTTATTAAGCATTAAAAAAACATAATATGTTTGCAGATATTTAAGAAACATGGTAAGTGAACATTTTTGTTTATGTGAAAAACAATGCTAGGATCAGATATTATGCTTTGAAAATATGAGCTACATGCTGGAACGGCTGTCTTTGTTTTTGTTTTTTTAACCCGCCCAATGCCAGTTTAGCCAATTATATTTCAGCACCCTGCGTTGCCTTGAAGGAAAGCTGAGTAATTCATTCATTCATTCATTCATTCATTCATTCATTCAGTCAGTCAGAAAGGCTCTCAAAGTGTTTGACCACAACCAAAATGCAACCTCTTGTGGACAGTAGCAGCCTCCGAAATGAGACTCAGATTCAGAGTTCCACATGAGGTTGTAAATTAGCAAATAATATAAGTATAACGAGCGTAAACATTGGGTGAGAAGGTTACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32974
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000056536 Nonsense 878 1036 17 19
ENSDART00000141784 None None 561 None 11
Genomic Location (Zv9):
Chromosome 2 (position 37652954)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 37932086
GRCz11 2 37914543
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATGTGGAGAACATGGACAGAGTCTATAACATCCCACCACCACAAGGATG[C/A]CAAAAGGAGCCTGAGAGATCTGCTGACGTCATGCCACTTCAAGCAACACC
Long Flanking Sequence:
AACCTGCTGAATTAGCTAGATTTAATAGATTTTTATTCAGTATATGAATAATCTTTTAGTTTTGAATTAGTTTTTTTACATTAATATTTAGTAAATATACTAACATATACTAAATTTAGTTATTCAAGTAAAATATCGCCAGTGTTTCCAGTTAAAAAGTAGTTATAAGGTCTTAAAATGTATGGAAAGAGTCATTAAAAAGATCTTCAAAAGGTATTAAATTTTACTCTTTAATTCCTGTATATACTCTGATTATAGACATGAGCTGCTGCATCTGTGTGCTTTAATATGTACATTGTAGATGTTTTTTATGCATTTATGCTTGAGCCGATTGCATGACTACATTTGGATGTACGTTCTCTCAGTGGCTGGAGTTGTTTTAAATGCTCATTCAAATGTGTTCTGGGATGTAGGTTTGTTTCTGAGAGAGGCTCTTCAAGGATGCTGCAGCATGTGGAGAACATGGACAGAGTCTATAACATCCCACCACCACAAGGATG[C/A]CAAAAGGAGCCTGAGAGATCTGCTGACGTCATGCCACTTCAAGCAACACCAAAGTTCAGGTATGACTATTAAAAAAGAATATATAAAAGATAAATAGATCAGTAACTTTGTCCAATTTGTGTCTAGAATAAGTTCCAGTGTAGAACAAAATAAGCTGTGAATACGAAGTTCTGAAAAATGGTTGTCATTTAGAGCATGCTTTTTCTCAGAAAAGTACAATTATTCAGCATTGGAATTATGTTTGTCTAAAAAAATAAATACAAAATTACACACTTTTTTTGTATTTTATGCAAAAAATGCTCTAAATAATTTTTTTATTTCAAATGAGGAAAAATGTTATCAGTAGTTTAACTCAAGCACACAACAATTAAGTGTTTTTTTTCTCCATAGCTCTGTAAATGTATTGTTAGAAGGTCAAATATATTTCCCACCCTAGATAAAAAAAAAGAAAAAAAAAACATGAATTGAGTGTTATTCTGAGATAACAACCACTGAATAAC
Associated Phenotype:
Not determined