ZMP

med31

Ensembl ID:

ENSDARG00000008020

ZFIN ID:

ZDB-GENE-040718-114

Description:

Mediator of RNA polymerase II transcription subunit 31 [Source:UniProtKB/Swiss-Prot;Acc:Q6DH26]

Human Orthologue:

MED31

Human Description:

mediator complex subunit 31 [Source:HGNC Symbol;Acc:24260]

Mouse Orthologue:

Med31

Mouse Description:

mediator of RNA polymerase II transcription, subunit 31 homolog (yeast) Gene [Source:MGI Symbol;Acc:

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa43709	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa6684	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa43709

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000124416	Essential Splice Site	8	136	1	4

Genomic Location (Zv9):

Chromosome 21 (position 38885868)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	21	40025933
GRCz11	21	40049486

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GCGTCGTCTGAATTCTCGTTGTCCGTAATGGCTGGTGTTATGGAAACAGG[T/C]TTGTTAAAATTAGATTGAATTGTTATTTAGCACATCTTTGCCCACGAGAT

Long Flanking Sequence:

TGTTTCAGTCCCTACTTTTCGACATTTTCTCATTAAAGTTGACTCCTGCTCAAATCTTTGCGTACGTGTAACAACAACAAAAAATGTGTCAGATACTTGGCTCTACATGAAGAACTGTTGACTCTGATTTGAGTTAAATAGCTCTTAATTAATTTATTTTTATACAATTTTATACAAGTGTAATTTACTTACCCCTTACAAATGTAGTTTGTATTGTTCCTATTTTGTATCTCTCTTATATTGATCTCCTGATTGTGGTTGTAAGTTTTCATTCTTTATTATTTAAAAAAAAGGTGCAAATGTCGTGAAACACTTTTACGACAGCAGCACTGGTTTTATGGCAAAAATGGCGTCAGCGGTCTATGTCCGCATAAACAATGAGTAATGTGTTGTTTTTGGTAATCGCGCTCTAAAAAATCTTTTTATACTAATCATTTTCCAGATATTTCAGCGTCGTCTGAATTCTCGTTGTCCGTAATGGCTGGTGTTATGGAAACAGG[T/C]TTGTTAAAATTAGATTGAATTGTTATTTAGCACATCTTTGCCCACGAGATTCCTAGCAATGTGACAGTTAACGTAAATACAATTGTTTGGTAACGTATTTTAGTTTCGTTTTGATCATATTAAGTTATACAACGTTTTAGAGGTACTACACTATGTGTTATTTTCTGTACTGGCGCAGATATATGTTGTTCAAGCAATTTCTGTAACACTTAACATTAAGGTAGTATCGTCGTTAGCCAATGTTTGCTAACATGAACAAACAAGAATCGTTATATTTATTACAGTGTTTGTTCGTCTTTGTTAAAAGTATTAATGAAATAAAGTAATCTCAACTTACGGTGCATCAACTAATGTCAAGCATGAACTTGCATTTTAATTATGCACTAATACAAGTATTGTTCGTTGGTAGTTCATGAATACATTTACTAATGATTATTTGTATTATTTCTTTTCAAACACAAACATTGCTTACGCTTCTATTTGTGCTTTGACAGACGAGC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa6684

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000124416	Nonsense	122	136	4	4

Genomic Location (Zv9):

Chromosome 21 (position 38881980)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	21	40022045
GRCz11	21	40045598

KASP Assay ID:

554-5390.1 (used for ordering genotyping assays)

KASP Sequence:

ACTCCAGAAAACGCACCCGTTTACAGCAGGCGCTGGCGGAACAGCAGCAA[C/T]AACAGCAGCCACAGGCTCCATCACATGCMAACMCCACCTCCAAATGAGAC

Long Flanking Sequence:

ATTCAGCTTAAACTGAAATTCGAAAGCTTAACTACAATAATAGTTAACTAATTAGAGACATTTTTTGTTTTGTTTTGTAGATAAGTGAAAAACAATTTCTTAATGGTATAATAATATTGACATTCCAGCCAAACTAAAAGAAATAAAACTTGTAAAAGGAATCAATATGAAAAATGTCCTTGTTTTATTAAACATCACTTGGGAAAAATCTTTAAAAATAATACAAATTTCACAAAAGTGCTAATAATTTATTATAGCTTTTTTTTTTTTAATGTAATTTGAATTGATCTAAATATTTCACTAACGCAGTTTAAATCTTTGTGTATGCTAGATATCCTCATTGTCTGCACATGTTGGAGCTGTTGCAGTATGAGCACTTCCGGAAGGAGCTGGTGAACGCACAGTGTGCCAAGTTCATAGATGAACAGCAGATCCTGCACTGGCAGCATTACTCCAGAAAACGCACCCGTTTACAGCAGGCGCTGGCGGAACAGCAGCAA[C/T]AACAGCAGCCACAGGCTCCATCACATGCCAACACCACCTCCAAATGAGACTCAAGCTTTTCAGATGGGCTTTTAGATATTTTTACAAACAGACTTTGACTTTCACACTGCTCTCTGTAGGCCAATAATGTTAAGTGTGTTTGAGCGACAGGAGAGTAACGGTAAAAAGAAGGTAAGAGGAGAGTGAAATCATTTGTATTACACTTTTCTGTTCTAGTATGAATTTGTGAATAAACATTTAATTAGTTACAGATTTAAATTTCTTTATTTGCTCGAACTCCATTTGTTACCTGCTTCAGTTATTAAATATGTTTATTATGCTTGTGTACATTTTGGACAAAAATAAACATAAAATAAAATGATTAAAAAAAAAAATCTGTTACTTAATTTTATAAACAGAAACTCTTAGAGGGGTCTGGATTCAGACCAGGTGCAGCTGTAAGCTGAGCTGCGTGCAATTCTTTTAATGGCCACAAATAACCCCACCTCAACTCTACCCCT

Associated Phenotype:

Not determined