ZMP

map2k1

Ensembl ID:

ENSDARG00000007825

ZFIN ID:

ZDB-GENE-040426-2759

Description:

dual specificity mitogen-activated protein kinase kinase 1 [Source:RefSeq peptide;Acc:NP_998584]

Human Orthologue:

MAP2K1

Human Description:

mitogen-activated protein kinase kinase 1 [Source:HGNC Symbol;Acc:6840]

Mouse Orthologue:

Map2k1

Mouse Description:

mitogen-activated protein kinase kinase 1 Gene [Source:MGI Symbol;Acc:MGI:1346866]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa43086	Nonsense	Mutation detected in F1 DNA	Not yet available
sa6511	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa43086

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000025107	Nonsense	201	395	6	11

Genomic Location (Zv9):

Chromosome 18 (position 19227937)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	18	19458160
GRCz11	18	19447226

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ACCTTGTCTCAACCTTGCAGATGTAAAGCCATCTAACATCTTGGTCAACT[C/A]GCGTGGGGAGATCAAGTTGTGTGACTTTGGTGTGAGTGGACAACTCATTG

Long Flanking Sequence:

GCATATAAACCCATTTGTGGAGAATTAGAACAATTTATTATATTGAATAAATGCACTCTATGGCATCTTTAAAGTCATTGCATTTCCATAATTCGACGCTTTATAAGGGTATGTGGTGGACATTTTTCCATAAATATTGTTTCTTGTAGGATGGCGGCTCTTTGGACCAGTGCCTTAAGAAAGCAGGCAAGATCCCAGAACAAATACTGGGCAAAGTTAGCATTGCGGTCAGTATTTCCTTCTCAAATGGCTGTCATGTGGACTGTTTACAGAAATAAGGCTAATGGGCATTGCTTAATGTGTCTGGATCTGTTTTGTCTTCATTCATGCAGGTGATTAAAGGTCTGTCATACCTGCGGGAGAAACACAAGATCATGCACAGAGGTAAATGATGATCTTGCATCATCTTCTGTTGATTTATTATTTTTGTTGAAACTTACTGAAGGGAAGACCTTGTCTCAACCTTGCAGATGTAAAGCCATCTAACATCTTGGTCAACT[C/A]GCGTGGGGAGATCAAGTTGTGTGACTTTGGTGTGAGTGGACAACTCATTGACTCCATGGCCAATTCCTTCGTGGGAACCAGGTCCTACATGTCTGTAAGTAAACAATATATATATATATATATATATATAGTTTGATTGATTGATTATTGATTATTAATAATTTAACAAAATCAATACATATCATAATAGAAAATGTATATTTTAATTTTTGGTTGATTTACATTTTATGTTTACCAGTATCTTACGTTTTTAATTACAATTGTTACTTTAATGTAGTTATTAATTTTATGAATGTATGTGTTATAGAATTTTATATTATATAAATATATTGCATTATAATTTTGTTTTTATATTGAATATTTAATAATCAATTCAATATTTATATTAAATATGTCTCGATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGCTTATTTACCCTTTTT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa6511

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000025107	Nonsense	319	395	8	11

Genomic Location (Zv9):

Chromosome 18 (position 19230362)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	18	19460585
GRCz11	18	19449651

KASP Assay ID:

554-5443.1 (used for ordering genotyping assays)

KASP Sequence:

TACGGTCCAGACAGCAGACCTCCCATGGCTATATTTGAGCTACTTGATTA[T/A]ATTGTCAATGAAGTAAGCTTTCAGTGGCGCTTACAAGATCACTAAACTGT

Long Flanking Sequence:

GGTACATTTTTGACCTAATCATTTTCCCCTTGATGTTTAATTTGGATCATCTCATGGGTGCCATCTGTTTGTTCAGGCTCCTGTTTTCCATCAAATCTCTTCCTGTATGATAGCGCTCATTTCCTCCCCTTGTGATTTTCCTTTTTCTCCGTGTCCATCTGTAGCCCGAACGCCTTCAAGGCACTCACTACTCTGTCCAGTCTGACATATGGAGCATGGGTCTCTCTCTGGTGGAGATGGCCATCGGACGCTTCCCGATCCCACCACCTGATGCCAAAGAGCTGGAACAAATCTTCGGTCAGCCCCTGGAGGGAGACCCATCAGCCAGTGACACTTCTCCAAAACCCAGGCCCCCTGGTCGACCTGGCAGCTGTGAGTTAAAACTCATGTACTTGATAATGGAACTAATATAATGAGATAATATATGTTTTTTATGTTTGTTTTTCAGCATACGGTCCAGACAGCAGACCTCCCATGGCTATATTTGAGCTACTTGATTA[T/A]ATTGTCAATGAAGTAAGCTTTCAGTGGCGCTTACAAGATCACTAAACTGTTTTATGGCAGTGAATTAATTAAAGTGAGGATTTATTGGCTGCTTCGCTGAGATTTAATGGAGCTGTGTTTTTTTTCAGCCACCTCCAAAGCTACCAAGTATCTTTGGTGCAGAATTTCAAGACTTTGTAAACAAATGGTAAGCAAAGATGTTATCTTTGAGTTTATTCCTGTAGAGCTTGGCATTAGTGATGCCAAGGTCATTGGTTTGATTTACAAGGCAACTGGCAAACTGTTGAGAAGCAAAATGCACTGAAAGCTGCTTTAGATAAAAGCATCTGTTGAATAAAAGCCTTTTCAGCGGTGCTTACTGCGCCATCTAGGGGCATAGATTGAAATGTCGCCTTATTGTAGTCCTTGAGTGGACATGGCGATGGAAAAATAATAAAACGGGTCCAAGTTTTCTGTGTTTGCGAGCAAAATGTTGGCGATTAAGCTTTAATTTGAAGCAT

Associated Phenotype:

Not determined