Busch Lab

ZMP

plekhg7

Ensembl ID:
ENSDARG00000062855
ZFIN ID:
ZDB-GENE-070410-15
Description:
pleckstrin homology domain-containing family G member 7 [Source:RefSeq peptide;Acc:NP_001038464]
Human Orthologue:
PLEKHG7
Human Description:
pleckstrin homology domain containing, family G (with RhoGef domain) member 7 [Source:HGNC Symbol;Ac

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa6507 Nonsense Mutation detected in F1 DNA Not yet available
sa23266 Essential Splice Site Available for shipment Available now
sa23265 Essential Splice Site Available for shipment Available now
sa23264 Essential Splice Site Available for shipment Available now
sa23263 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa6507
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091339 Nonsense 73 769 1 16
ENSDART00000127769 Nonsense 73 769 2 17

The following transcripts of ENSDARG00000062855 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 18 (position 15606026)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 15958438
GRCz11 18 15926950
KASP Assay ID:
554-5088.1 (used for ordering genotyping assays)
KASP Sequence:
TCCTTGCACAATGCGAATAAATTTYGACAGCACGTCATCAGGCATGAAAT[T/G]AGGTTCTGTGACAACGTCAAATTGCACGTCTGGGGACTTGATCACTCAGG
Long Flanking Sequence:
TTCTTTCTGTTGGGTCTTAATCATAAACTTCTAGTTAACACTCTGTTTCATTGGGTTATCTAAAATGTGGAGATTACTTGGGTTTAAAATAGGCATACTGTACCGGACTAGTTCTGCAAGAGTTCAAATAAACATAGTGGGTGGCTTTTCTAATCCTTTCTTGCTTTTCTGAAACTCCAGAGACATCGGATTGGACACATTTTTGTGGGAATGACTCAAGCCAAACTTGCATCTGATTCCTAATCTGTCTTCATTCGTGGGATATAATGCCAGATTACTCAAGATGACGGAGCTGAATTATGCTTTCATAAGTGAAAACAGGAAGGAAGTGGATAAAAGTTTGGACTGGAGTTATATAGACTGGCATGACAAGAAAATGGTAAAAGGGACGGATGCTCAGACCCAAACCCAACATGTTCATAGCAAGGACATAGACACACAAACGACTAATCCTTGCACAATGCGAATAAATTTTGACAGCACGTCATCAGGCATGAAAT[T/G]AGGTTCTGTGACAACGTCAAATTGCACGTCTGGGGACTTGATCACTCAGGAGATTCACAGACATTCCCCGGCCCCCATCTCCCCATCCCAGACTCAGAGGAGGATGCCCTTGCCGTTACACACTCCGAATTTTCACAGACATTCCCCAGCCTGCTGCTCCACATCCCCGGCTTTATGGAGGTCATCCGGGATGTCATACTCTGTGGATTTTCACAGACATTCCCCAACCCGCATCTCCACATCCCCGACTCTGAGGAGGATGAGGAGCACCAGAATCTACAACCGGGAGACCAGCAATCCAGCCAAGCCTTTAAGAGAGGAGTCTTCAACCCCAATGAGTCCACATTCTTCATTTTTTCGAGAAAAATCTCCACTGGCGGCGGATGAGGAGAACAAGAGTCCTGAATCTTCAGTGACTCCCGGGACAGTTCGTACACACAGATCACAGACACTTGACAATGGTTCCATCTGCAAAAGCAAAGAGTCTTGTGATTCCAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23266
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091339 Essential Splice Site 262 769 2 16
ENSDART00000127769 Essential Splice Site 262 769 3 17

The following transcripts of ENSDARG00000062855 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 18 (position 15602432)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 15954844
GRCz11 18 15923356
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTTTTGTATCTGCTTTTGATTACAGGTCAAGGATCCATGTCATAAAAG[G/A]TAGGTGAGCTGTTTCTAATCTAAAGTTTTGCATAAGCCATTCACTATTTG
Long Flanking Sequence:
CCTTTAGATAACAATCAGATTCATCAACAACGATAAGTCATCTTTTTCCATGCAGCTTGTAAATCACCAGCAATAGCCTTTCCGCTTTTATCAAAGAATGCCTCTTGCATCGTTCCCCTTCGACCTCCCGAGGTACTAGTTCACAATAAGAGCTTCTGACAGCAATTGAATCAGCAGCTTCATGCACTGGCAGCTTCGTTCCATTCACTCCAGTCAGCAATCACCAAATAATGGAAGGGTCAGTGTAGGATCAGAAGTATAAAAGCCAAGCCCTATTCACTCCATCCATACATTCACCAAGCCTTCCCCACAATGGACTGAGATATCAGTAGATGTGAGACCTTCAGAGGTCTTTTTAGCTCACAACAATTGTGTGACGGGATTCGCTGAAATTGATATCATGTTTACTTGATGACTAGGGTTTTGCTGTCTCCAAGTACTTTGCTCACGTTTTTTTGTATCTGCTTTTGATTACAGGTCAAGGATCCATGTCATAAAAG[G/A]TAGGTGAGCTGTTTCTAATCTAAAGTTTTGCATAAGCCATTCACTATTTGCATGTGAGCCATATTTTTGTCCTAGTCATTTTGGTCTGTCAAAGTAACATTTCCCTGTTCACTTGTTTCTCAACATCTACCATTTGAAAAGTTGTGTCATTATTCATGGAATTTGTTTTCGTTTGTGATAATGAGGCCAAAGCGGGACACTTTTTTTCAGCAGAGCGCCACCATGCTGGCGCAAGGGGGAGCTGGGATTGTAGGACGTTCATTGTTCATTGTGTTGCCGCTTTGTTAGCTGCGCATGAACTTTTAAAGGAGAGTTATTAGAGATCCATCGTTCGGCCCAGACAAACTCTCATTAGTGCCACTTTTCCCCTCGTAGGGCCCTCTTTGCTTGGGCCACGCTCATCTTTTCAGCGGTGGATAATTAGGCAGCTATTGTGGCCTTAATTACAGTATGGCACCGTCTGATTGCAGTGCTCATCTCTGGACGCCGATTGGATGGGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23265
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091339 Essential Splice Site 347 769 5 16
ENSDART00000127769 Essential Splice Site 347 769 6 17

The following transcripts of ENSDARG00000062855 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 18 (position 15590371)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 15942783
GRCz11 18 15911295
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTCTGTTCAGGTCCCCGAATGGAGAGACACAGACTTTCAGACCTTTAAG[G/A]TGAGAGTCCAAAACCGATGGAGGGAAATCATTTTGAAAACCACTGGAGAT
Long Flanking Sequence:
TTGAACACCTCTGTAGCACGCTTAGAGCAAATATTCTCATATTTTAATGCTTCAATACCTTCATGTCAATATCTCACCCATGACGTTTTGATCTGATGCCAGTTCTGTGGTTGTTGCCATCTGCAAAACCTCTGTTGTCATTTTTCAGATGCTTTGCATGATGTCTAGCACATAGTGTTCACTGACCCACTTTGAGCCAAATCAGATTTGAATGTACGCACATCCTCCCCCCCTCCCCAATCAATTCCATTAACAGTAAACAACAACAAAACGGGCATGTCCAGCAGAGCTTCAACACGTCGCTCTTTCCAATCTGCTCCACAGTTTTATGCTCAAACACAAAGAGAGCTGTTGAGGGCAGGCCAGAGTGATGCTGAATTAATGTGAGTTCTGTTTTCCAGCAGACAAAAGTGAAAACTCGCAGTGGAGCTGACATTGACAAGTGTCTGGCTTCTGTTCAGGTCCCCGAATGGAGAGACACAGACTTTCAGACCTTTAAG[G/A]TGAGAGTCCAAAACCGATGGAGGGAAATCATTTTGAAAACCACTGGAGATCAGCTTCTGAGCACATTAGAAGTCCTTAAGTTTTAAAAGGGTTTTCTTAATTACCAAGTGTAGAAAATAACAAAAAGTTCTTACCATGCTTTACAGTAAGTACATTGTTTGTATGACACGTTTTCTGAAATTGTCATAATTGTCCAGTATAGGTAAACTAAATACATATGCTTAATTATCCATACAAGTACAGAACAGGGTTTATTTTATATATGAAGAGTTCTTCTCTGATCTTTTATCACTTCAAAAATACCGTAATACTGAAACAAAAATGAAGTTTATATATATATATATATATATATATATATATATATATATATAAATATATATATATACAATATCTAACTGGAAAGACAAAAATGCAAGCAGAGTGTGATTCCCTACTTTTCCTTTTTTTGGTTTGTTTGATTAACGTTAATGACATAAAAAGCTGATTTTTTAGGTTTATTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23264
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091339 Essential Splice Site 428 769 7 16
ENSDART00000127769 Essential Splice Site 428 769 8 17

The following transcripts of ENSDARG00000062855 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 18 (position 15584375)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 15936787
GRCz11 18 15905299
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGACATCGACTCCTGGAGGCTCTTTGCAAATCTCAATGAGCTTTGTTTGG[T/A]AAGAAATTAAGGAGGATAATGTAACTGTAAATGTATTCAAACTGTGTTGA
Long Flanking Sequence:
CTACAGAAGAGTCATGCTTTAAATAGGAAAATGATCAAAACTCTTCTCGGTCGAGATACTAATGGCTGATTCAATTATCTATCATTTAAGCTAAGCTAAAAGTGCTCCAGACCTGGATATGAATTAAATAATAGTAAAACTGTTTAACTCTAGTCAACTTGTAAAAAAAACATTTTTCCAAACAAAAAATTGAGCGATTCTTTAAGAATGAGAAGTCATACATACAGCTTAAATTATTATTGTTGTTGTATAATCAATGCCTTAAAATTGTCTTAAAAGCAAAATAATATTACTTATCACAATTATTTCTCTCACAAATTGTCACACGAGAATTAATTATCTTGACAGGCCTGCTAACACATTTGATCGCTCTCTAATATGAAGTGTTTTGTTTTTGCTGTAGGTGTTCTTGACCACTCTATCAGACTTGCAAACGAGACAATGTCTACAGGACATCGACTCCTGGAGGCTCTTTGCAAATCTCAATGAGCTTTGTTTGG[T/A]AAGAAATTAAGGAGGATAATGTAACTGTAAATGTATTCAAACTGTGTTGATACAGTTTTTATTACTTCTTCTTCTGCTGTATAACAGGTCAGCTTCGGCTTCCTTACTAGTTTATTACGCGTCATTAAGGAGATGTGGACTGACCCGGACAGCTGTAGTACTCAATCTCTTCATGACCTTTTCAGAAAGGTAAGTTACCACAGGTATTTTAACATACGAGAATGTCACAAGTTAAGCGAGGATCCAGTTTATATACTGTATAAAAAGTATGGTCAAAACAGGCAGGGTCGAAAAACAAGCACACAACAATGTCCAGATGTGATCCACAAGAGAAATACAAATATCAATGCACCGCAATAACAAGTGTACGATCCATGTCATTTACATTTTACATTTAGTCATTTAGCAGACGCTTTTATCCAAAGCGACTTACAAATGAGGACAAGGAAGCAATTTACACAACCAAGAGCAACAATGAATAAGTGCTATAAGCAAGTTTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23263
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091339 Nonsense 571 769 11 16
ENSDART00000127769 Nonsense 571 769 12 17

The following transcripts of ENSDARG00000062855 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 18 (position 15572867)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 15925279
GRCz11 18 15893791
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTCTCTTTGTAGATGATCTTGAAGGGAAAGTCAAGTGGTTGGACAACTA[T/A]CAGAAGGTGAAGCAGCTGAAGGAAACTCTAGTGTGGCTTCCTGTTTGGGA
Long Flanking Sequence:
TGACTGCACCATTCCTTATGGCCAGACAGGCATGAAATTATTAATAGGTGAATGTCCTACACAAAAGCAGTTTCTTAATACAAAACATTCCAAGATGCCACTTTCTGAAGAACACACTTCATGACACATCTCTCATAACCAATATAAGGGTGTGTTCGACTCTTCCTGGTAACTTTTGTTCAAATCAAACAAGTGTGTAGGAGTCTACATCTAATGGGTGTGAGCTTCATACAACACAACGGCGGGTCATTGTTGATGAAAGAGCTATTACTTGAAATGCAATAGGAAGAATCGGGAATTTAAAGTCCGTCCGTTGTCTGCGGCTCAATAACCAAAAACAGGATCTGTTATTGTACACAAGCGCTAATGTTTGTGTGGACGAACCCGCTAACGTTTTATAGACAAGAGCCTTTGTGTGGACTGATAATACAATAGCATTTCCACCCTGTTTTTCTCTTTGTAGATGATCTTGAAGGGAAAGTCAAGTGGTTGGACAACTA[T/A]CAGAAGGTGAAGCAGCTGAAGGAAACTCTAGTGTGGCTTCCTGTTTGGGAGAGCGATAAGAGGGCACACGTTCCTGAGGTCTGTACATTTCTTTAGAATGGGCTTTATACACAGACTTTTCATTTTCAGTCATCCAGCCTAAGTGCTTCTGGTAAACTGTTGCATCATTACAAAATCACGTTTAAGATCTGATTTCTTTAAAAATCTGTGATTTTCACTGCCTGATTGATATACAAAATAAAGTGGGTATCAGAGGGGACAAGAAGCTCTGCATTAAATTATATTTTTCCACGCCATGTCTTTAAAATATGGAATTAATTTTACTCCAATATTTTCAATGGAGTTTCTGCACTGGCCTGCTGCTACTGATGGCACTTGTGTTTAAATGCTCTTTCTTCTTATTTTATGCTTAAACAACTAAATGAATGCTTAAGCCTATTGAACGGATTGTATTTTAAATACAACATCTATGCTGTAAAAAGAACCTTGTGAAATTAAAA
Associated Phenotype:
Not determined