Busch Lab

ZMP

tdp1

Ensembl ID:
ENSDARG00000073866
ZFIN ID:
ZDB-GENE-090909-1
Human Orthologue:
TDP1
Human Description:
tyrosyl-DNA phosphodiesterase 1 [Source:HGNC Symbol;Acc:18884]
Mouse Orthologue:
Tdp1
Mouse Description:
tyrosyl-DNA phosphodiesterase 1 Gene [Source:MGI Symbol;Acc:MGI:1920036]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa42901 Nonsense Mutation detected in F1 DNA Not yet available
sa23033 Nonsense Available for shipment Available now
sa6467 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa42901
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108712 Nonsense 222 615 3 15
Genomic Location (Zv9):
Chromosome 17 (position 16260952)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 16411780
GRCz11 17 16419713
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTATTTAGTTTAATTACTGCTTTGACATCCCATGGATGGTGGAGCAGTA[T/A]CCGCCAGAATTTAGGTAGGATGAAATCTTTTAAATGTTCTTGCAGTGTTT
Long Flanking Sequence:
TGAACTTATCTGGATATTCGACAAACTACAGTAGTCAACATTTAAAGTGAATCAAAAACATTTTTCATAATTATCCTAAGACAAGAACGAGTTGTGTTCAATAGATTTTGCACAACTTTAATGAAAGGTGATGATCCACTTCAAATGTTGACGACTGTATATATAGCATCTATAATTTTCAAGTGTGACATTTTTTTCAAGCTCCAAAAAGTGTAGTGACTGACAGTTAATGGGTTAAATATAAAAAGGTGAGTAAAGTTCTGATAAGGTGTTACTTAATCCTAATAATTTTCCTTTTGTCTTTTTCTCCATCTATAATTAGAGATACTTTCTCCAATGTTTGGAACATTGAAAGAGTCTGTACAGGTATTTTTTTTAAATAGATGAAGTGTAAGAATTTGCACTACTAACCACAAACAACATTTGTAATGCTCATTTTTAATACTTTTTTTTATTTAGTTTAATTACTGCTTTGACATCCCATGGATGGTGGAGCAGTA[T/A]CCGCCAGAATTTAGGTAGGATGAAATCTTTTAAATGTTCTTGCAGTGTTTGATGTGGATTGAAAATATTTTAAACACATTTAAATGATTACTTATTCTTCTTTGTTCTTTAGAAACAAACCAGTCGTACTCGTTCATGGAGAAAAGAGAGAGTCCAAGGCTTGCTTAATTGAGCAAGCCAAACCATACCCACATATTAGTTTTTGCCAGGTATTGTCAATTTATCGTTCTGTTGACTTGCAATAGGCTTTTTATTCCACTAGAGGGAGGCATTCAACTTTATGGAAAATTGAGATCCTATAAACTTTGTGTTCAGTTACTGTGTAACGTGTGCATAAAATTTTAACATAAGTGTAAAAACAAAAATTGTAACTACACATCATGTGAAAAAAAAAACACTAAATGCTTGTTGAATTCAACTCTTATGTTTTATGTTTTAGGCCAAACTGGACATTGCATTTGGCACACATCATACGTGAGTGATTTATATTTCTTGATAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23033
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108712 Nonsense 392 615 9 15
Genomic Location (Zv9):
Chromosome 17 (position 16243934)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 16394762
GRCz11 17 16402695
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGCATGAACTCATTGTTTTTGTTTCCCTCAGTTGCTCAGCGAGCATACG[C/T]AACCCATGCAGAACGAAGAGCGATGGCACGTGCTTGGCCAGTTCTCCAGC
Long Flanking Sequence:
GGTTTTTGTAAGAATATTGGGTTCATGCGGGTTCCAATAGATCTCATACAGTATTTGTGATGATTGGAATAAAAATCTACCTTCTTCCACTTTTCCAAATGATCAACTAGAAGTCAAGTTAGTATTTGCTGCTCTTACTACTGGGATCGACAACAAGACTTTTGTCAGGTAGTGTAAGGTGATGTCAAAAAAAGCTGATCAGTAGAAAAAATCTATTTAGGTAAAAATGACGAATAAAGATATCCTAGCAATAGATTAACATACTGATACTAACCTAATCTTTCAAAAAAAAAACATTTTAATTTCATGGGAACTCTAAACACTTCCTACTTTCTTTTTTCTTTTCCTATCTTCTTTTGTTTACGTCAAAGGCCATGTGGTCAACAGTGCTGCCGAGTCATCCGTCACTTGCTAAAAGCTAGCCAAATTAGACAGATGCTAACATTGACATTGCATGAACTCATTGTTTTTGTTTCCCTCAGTTGCTCAGCGAGCATACG[C/T]AACCCATGCAGAACGAAGAGCGATGGCACGTGCTTGGCCAGTTCTCCAGCATCGGCTCCATGGGCCTTGATAAGACTAAATGGTTGGCAGCCGAGTTCCAGCGCACTCTGACCACACTGGGGAAGGCAGGGAAATCATTAGCCAGTCCAGAAACACAGATGCTCCTGGTGAGTGTGTCGAACAGCCCCCGCAGTGCTGAAGCGGTGAAAAGATCTGCTCATATCGCTGCCGAACCCTCTCTGGATTGCTAACAACGTGGCCAGATGGATATCACAATAAACACAGTTGCATATTCTCCTAGCAGCTTTCGTATCTATCAGGATAAATGAGCCCTCAATTGTGTTTTCATTTTAATTAGGTTGGAATCAAAGAGGAACAACAAAGTGCACATGTGCGCCTGCCTGTTTTTTAACGCAGAAGGCATCCGCTTTCTCTGAGCTATGAAATTTGAAAATTTGTTGACATCCCGGGTGTCTAATTAGCAATTAGTATTTTTAGCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6467
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108712 Nonsense 478 615 11 15
Genomic Location (Zv9):
Chromosome 17 (position 16240941)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 16391769
GRCz11 17 16399702
KASP Assay ID:
554-5017.1 (used for ordering genotyping assays)
KASP Sequence:
TCCCTTYAGCTGGAGGATCTTTACCTTACAGYATACAGACGGCACAAAAA[C/T]AGCTCTGGCTTCATTCTTACTTCCAGTAAGTTCTTYTTTCTCTTTCTCTG
Long Flanking Sequence:
AGATTTGTATGATTACAGTTGATCCGCTTAAGTCACATAGAATGTTTTTGGTTCTTTTCTGGACTTTAAACACCTGTTGCTGTCTATGGAGGATGTGGGAGCTCTTAGATTTCATCTAAATTATGTTAGTTTCTATTCCGATAATCAGGTCTCAGGTGATTAGTACAACACGAGGGAGAGTAATCAATTGCAAAATTTTAGTTTTGGGGTGAACTAACCCTTTAAATAAATAAATAGATGGATCAACCAATAATTTAAATAAATTTATGGATAAATGAATATAAAAATGTGACAACTCCTTAAAATCTTGTCATTTCTAGATTTACCCATCTGTGGAAAATGTGAGAACCAGTTTGGAGGGCTATCCAGGTATCATTCATTCTTTTATTCTAAAATAAAAAAACATCACCTCCAGTCATTATATGACAACTGACATTTCTAGTTCTCTTATCCCTTCAGCTGGAGGATCTTTACCTTACAGCATACAGACGGCACAAAAA[C/T]AGCTCTGGCTTCATTCTTACTTCCAGTAAGTTCTTCTTTCTCTTTCTCTGTTTTAACAATATTCTCATCAATATTCTGTCATTTTAAAATGCAACTATAAAAAAAGGCTCCTCAGACTTTGTGAGTTAAACAGCTGCCTTTCCCCAAGAGCTGTCTGACCCTTCAATGCTCCATAGAAATTTCAATTGGGTTCTTATCCCATCGCGCCCACCATTTTAAGACATTATCGCCATAAATAAGCTATTTTGCTGGTGGCCTCAATTTCGCTAAGTGATCGTAGATGGGCATATTGCAATGTAGATTCAATCTTAGTCTCCCTCTGGAGTACGCACTCTACACTCAGTCTGTTTAAATGAGTCCATGTAGATTTTTTGCATTCATGTCTGAATACTGACAGCAATCAGACAGAAAGCTCTCCTCTCAGTCTGCACAGTCTGCCCTAAAACACCAGCTCTCTGCACCTGCAAATGGCACGAAACGATTCTTTGGGTGTTCTCACG
Associated Phenotype:
Not determined