ZMP

A7YYF5_DANRE

Ensembl ID:

ENSDARG00000060532

Description:

Zgc:173905 protein [Source:UniProtKB/TrEMBL;Acc:A7YYF5]

Human Orthologue:

ADAM22

Human Description:

ADAM metallopeptidase domain 22 [Source:HGNC Symbol;Acc:201]

Mouse Orthologue:

Adam22

Mouse Description:

a disintegrin and metallopeptidase domain 22 Gene [Source:MGI Symbol;Acc:MGI:1340046]

Alleles

There are 5 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa6446	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa14978	Nonsense	Available for shipment	Available now
sa19148	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa36238	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa6446

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > T

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000085376	Essential Splice Site	35	237	3	9
ENSDART00000125590	Essential Splice Site	206	918	8	31

Genomic Location (Zv9):

Chromosome 16 (position 46077742)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	16	43331035
GRCz11	16	43234793

KASP Assay ID:

554-5073.1 (used for ordering genotyping assays)

KASP Sequence:

CACACACACTATATTCAGTTCTCCTTACTAATATTTTAGNTTTTTTTTTAC[A/T]GTTCATCTGGCAGAGTCACTTTTTGAAAACCCTCCATTGTTCAGTGCCGC

Long Flanking Sequence:

TAATTTACTTAATCATTGTAAGGCAGTGTGTATTAATTTTCTTTAAGTAAAGTCAACTAATCACATTTTACTGTGTACACAAAAATAGTTTTTGCTGCATGTTCAAACTACATATTTAAAATGAGCTAAAAGGCACAATTCTTGAGATTCTTTTGAGACAATATAATTGTTTTATGTTTGATCCACTTAAAATTATTAACTTAATCAATTTGTATTGGGACAACATGAATGAATTGGATGGAACCCTTCATTTTTTTTTTACAGTTTACAATGCTAAACACTGAACGACAGTTACTAAATTATAAATTAATAAATAAAACTATTTTAAAATATGTATTTTAATTATAGGTATGCTTAAATTATGGTAAGTCCAGCCCTGCAAGTATACACTACAATTCAGGCCCCATGAGTGGTAAATAATAGTGCAGAATGAGTCGGTTTTATTTTGCGCACACACACTATATTCAGTTCTCCTTACTAATATTTTAGTTTTTTTTTAC[A/T]GTTCATCTGGCAGAGTCACTTTTTGAAAACCCTCCATTGTTCAGTGCCGCCCACCGGAGAAAAAAGAGACAGGTGTGTGTGTATACAGTCTTAAAACAATCATAGCTCATGGTATGCACATGTATCTGTTAAGTTTTGACTATGAGACGGGATTGCAGTGCTGCTGTAAGTGCTACTCCAGATCTCTGTTTCTTCTGTGTCTTTCTTTTCCTCTCCATCTCCCCTCTTCTCATGAAATATTTAGAGCAGTGCTGTGGACACTTTATGGCACTAATGTATAGATCAGCTTTTTCCTCTGCAGTAAGCATGTTATGCATGCCGCAGCATGATATGAAACATATTCATCACTAGGTTTGGTTCTAAATTAGAATGATCGCTGTTCCAGATAATATAAGAATACAATTAGGTGATATTCAGTTCTGTCTCTCTGAAGCATCTGCAGTCTTTTAATGATGTTTGACAGAATGCTATAATCAAATTAAAATAAAATGTGTGGTAAA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa14978

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000085376	None	None	237	None	9
ENSDART00000125590	Nonsense	478	918	17	31

Genomic Location (Zv9):

Chromosome 16 (position 46099566)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	16	43352859
GRCz11	16	43256617

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

CTTKTTCTGCAGGAGTGTGCTAAAGAGGGGGAAAACTGCTGCAAAAAATG[T/A]ATGTTGACTCAGGGAGCCAAATGCAGTGATGGTCTCTGTTGTAAAAACTG

Long Flanking Sequence:

GGGTTGCAGTTGGAAGGGCATCCGCTGCGTAAAACTTATGGCGGAATAGTTGGTGGTTCATTCCGCTGTGGTGACCCCTGATAAATAAGGGACTAAGCCAAAGGAAAATGAATGAATGAATGAAAACGGTTACTGTTAACTATAATATTTCATTTGAAATTTTGTCGATTTTGTTAAAAGAAATTGCTAAATTATTTTCATTTTAAATCCATATGAAAATAAACAATACATGTGACAAATATTAGGACACTAAATGTAAAATGCAAAGTAACTGTGTTCTTTACTTCACGTTTTTGTTTTCGTTTGCAGCTCTTGGATCCTCCAGAGTGTGGAAATGGCTTTGTGGAGGCAGGAGAGGAGTGTGACTGTGGAAGCCCAGCCGTGAGTGATCTTCCATCAACATCACGATCACATTAATCTGACACTGCTTATGTAATCTCTTTTTTTCCTCTTGTTCTGCAGGAGTGTGCTAAAGAGGGGGAAAACTGCTGCAAAAAATG[T/A]ATGTTGACTCAGGGAGCCAAATGCAGTGATGGTCTCTGTTGTAAAAACTGCCAGGTAGGTGCTGAGTCATACAAGAAAGAAAAAAAAAAGTGCAGCTGTTTCTGTTTGAGTGAGATTTTTAATGATCATTGTGCTGTCTCTGTAGCTGGAGTTTATGGGTGTGCTTTGTCGAGAGGCTGTCAATGATTGCGACATACCGGAAATGTGCACTGGGAACTCCAGCCAGGTGAGGGCACTGTTGTGCACATCTCACAACACATCCAGCAGGAGCAGAATGGGTTATCTGCTTGTTATATTGTGTATCCACATAAGTTGTGACATATGGAATAGTGTTTCCAGGTCCAAGCCGTTACTCAGTTGAATATGCTATATGCACAGCCAGTGTTTTTTCCCCTACAGATAAACCAGGCCCGGCCCTAACCAATTTGGCGCCCTAGGCAAGATTTCAGGTGGCGCCCCGTCACATCGCAGTAAATTCCACTGCTAGTGTACAGTCATAA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa19148

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000085376	None	None	237	None	9
ENSDART00000125590	Essential Splice Site	496	918	17	31

Genomic Location (Zv9):

Chromosome 16 (position 46099621)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	16	43352914
GRCz11	16	43256672

KASP Assay ID:

2261-0225.1 (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TGACTCAGGGAGCCAAATGCAGTGATGGTCTCTGTTGTAAAAACTGCCAG[G/A]TAGGTGCTGAGTCATACAAGAAAGAAAAAAAAAAGTGCAGCTGTTTCTGT

Long Flanking Sequence:

GTTCATTCCGCTGTGGTGACCCCTGATAAATAAGGGACTAAGCCAAAGGAAAATGAATGAATGAATGAAAACGGTTACTGTTAACTATAATATTTCATTTGAAATTTTGTCGATTTTGTTAAAAGAAATTGCTAAATTATTTTCATTTTAAATCCATATGAAAATAAACAATACATGTGACAAATATTAGGACACTAAATGTAAAATGCAAAGTAACTGTGTTCTTTACTTCACGTTTTTGTTTTCGTTTGCAGCTCTTGGATCCTCCAGAGTGTGGAAATGGCTTTGTGGAGGCAGGAGAGGAGTGTGACTGTGGAAGCCCAGCCGTGAGTGATCTTCCATCAACATCACGATCACATTAATCTGACACTGCTTATGTAATCTCTTTTTTTCCTCTTGTTCTGCAGGAGTGTGCTAAAGAGGGGGAAAACTGCTGCAAAAAATGTATGTTGACTCAGGGAGCCAAATGCAGTGATGGTCTCTGTTGTAAAAACTGCCAG[G/A]TAGGTGCTGAGTCATACAAGAAAGAAAAAAAAAAGTGCAGCTGTTTCTGTTTGAGTGAGATTTTTAATGATCATTGTGCTGTCTCTGTAGCTGGAGTTTATGGGTGTGCTTTGTCGAGAGGCTGTCAATGATTGCGACATACCGGAAATGTGCACTGGGAACTCCAGCCAGGTGAGGGCACTGTTGTGCACATCTCACAACACATCCAGCAGGAGCAGAATGGGTTATCTGCTTGTTATATTGTGTATCCACATAAGTTGTGACATATGGAATAGTGTTTCCAGGTCCAAGCCGTTACTCAGTTGAATATGCTATATGCACAGCCAGTGTTTTTTCCCCTACAGATAAACCAGGCCCGGCCCTAACCAATTTGGCGCCCTAGGCAAGATTTCAGGTGGCGCCCCGTCACATCGCAGTAAATTCCACTGCTAGTGTACAGTCATAAGAAACAAAACAGCTTTTTGATCGACTACTACAAGCTGGGAAAATGTCAGATAAAT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa36238

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000085376	None	None	237	None	9
ENSDART00000125590	Essential Splice Site	637	918	22	31

Genomic Location (Zv9):

Chromosome 16 (position 46104724)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	16	43358017
GRCz11	16	43261775

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GGATTGACCTCTTTCTCTGTGGCCCAGCACAGCGCTTCACTGGATTGCAG[G/A]TACACACGCACGCACACACACACACACACACACACACACACACACACACA

Long Flanking Sequence:

TTCATTCATTCATTAATTCATTTTCTTTTCAGCTTAGTCCCTTTATTAAGCTGGGGTCACCAAAGAATTAGTTAAAAATTTATTTTGATTTCAGAAATAATGAGTAAAAATAAAGTCAGTTTTTCTATGAAAAAAGCAAATCAATTTGCCAAAGAGTTAATCAAAATAATCTTGTTTTTGCTTTGAAATAAGGAAAAAGTCACTTAATTTTGTTACACACTTAACATATTAGTTCTGAGAACAAGACAATATTTACTTTAAATATTTATACTAGAAACTCAAGAAAGGCTTTTTTTTCGCAGTATTGATGAGATGTCTGGTCTGTGGCGGGGAAAGATATTTAAAAGTGTGTGTGTGTGTGCGTGTGTGTCTGTTTTCAGGGATGTTCACTGTGGATACCTGCTGTGCTCCAACATTTCTCCAGCACCTAGACTAGGAGAGTTACAGGGAGGATTGACCTCTTTCTCTGTGGCCCAGCACAGCGCTTCACTGGATTGCAG[G/A]TACACACGCACGCACACACACACACACACACACACACACACACACACACACACACACACACACTATTTCTTCAGCTTTCTGTGTGTACTTTGATTTTTCTGAATGGAGTGTGAATGTTTCAGTGGAGGGCATGTGCTGATTGATGGTGACACTGATCTGGGATATGTGGAGGACGGGACGGCTTGCGGGACGGATCGCATCTGCTTTAATCACAAATGCCTCCCAGTGCAGGACTTCAACTTCAGCACGTGTCCCGGCACCAATGAAAGAGTGATCTGCTCAGGACATGGGGTGAGAGGTTGTGTGTGGGGTGTGAACTGGGACTGTTTTTTCACCCGTTGATCTAATTTCAGCTTCAGTGCTAAGTGCCATGAGAAAATTTGCTGGATATGTATGCACAATATATATATTTTAAATGGTAAAATTCTATATATTTTTATTAGAAAACTATATGTCTAATAGTACTAATACACTCACCAGCCACTTTATTTGGTACACCT

Associated Phenotype:

Not determined