ZMP

si:ch211-160j6.2

Ensembl ID:

ENSDARG00000054978

ZFIN ID:

ZDB-GENE-030131-3724

Description:

Novel kinesin motor domain containing protein [Source:UniProtKB/TrEMBL;Acc:Q1LXY1]

Human Orthologue:

KIFC3

Human Description:

kinesin family member C3 [Source:HGNC Symbol;Acc:6326]

Mouse Orthologue:

Kifc3

Mouse Description:

kinesin family member C3 Gene [Source:MGI Symbol;Acc:MGI:109202]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa644	Essential Splice Site	F2 line generated	Not yet available
sa29094	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa644

Status:

F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000077251	None	None	937	None	20
ENSDART00000132184	None	None	690	None	13
ENSDART00000138075	Essential Splice Site	None	88	2	4
ENSDART00000138511	Essential Splice Site	None	115	2	4
ENSDART00000140357	Essential Splice Site	102	140	2	2
ENSDART00000145288	None	None	753	None	16

The following transcripts of ENSDARG00000054978 do not overlap with this mutation:

ENSDART00000145063

Genomic Location (Zv9):

Chromosome 18 (position 43975659)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	18	45564714
GRCz11	18	45561668

KASP Assay ID:

554-0553.1 (used for ordering genotyping assays)

KASP Sequence:

AGGRCACCGATGTTGATATATCTTGTATGTTTCTGCTCTGTGTGTGCGCA[G/A]CCCGTCCAGCGGTGTGGTCTGCTCGGCCCTGCGGTCATGTACGGCACACG

Long Flanking Sequence:

GTTTGTTTGTTTGTTTGTTTATTTGTTTGTTCATTTTTTTACTTTGATTTACTTTTTACTTGTATTTATTTTTTTTATTTTTTTATTTATTTTTTTTTATTTATTTTTACTTTTTATTACTTTAATTTTTTGTATTCATTTTATTTTTTATTTTTATTTATTTATATATATTTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGAAAACGTTGACGATTTTGGGATCAATTATTATTTGTTTTGACAAGTTTATTTTGCTTACCCCATTTTCAGATTATTTAGCTTGTTTTAAGAAAAAACAATCATTTTTTACGCATTGTTTTTTAAAACAAGACAATATGCTTTGCTTGTATAGAAAATGCTTCTTGATTTAAAAAAATTTGAGATATTTGGACTAGAAAGAAGATTTTTATTCAGGACACCGATGTTGATATATCTTGTATGTTTCTGCTCTGTGTGTGCGCA[G/A]CCCGTCCAGCGGTGTGGTCTGCTCGGCCCTGCGGTCATGTACGGCACACGAAAGACCTGGGACGTTGGCCACACCCCCTGCCTGCAGGAGCTCTGGAACAAAGACATCTCATTGGATGGTAAGCACGGTCACATGACTACTTCAAAACCAGTGTGGCAACATTTTTCAGAGGATAGCAGGAATGTTTGAGTGTGTGTGGAGCAGCGGAAAGGAAAAACTCAGAGCAGACGTCAGATTGAGAAGAGCGAGTGATGCATTCTTGCAGAGAGATCAACGTGCACTCTTTCCTTGTACAGAAGAGTCAATCTCCTTAAAAAACCAGAGGAGGGCTTGAACACTAGGAGTATTGTGTTTGTTGGAAGAAGAAATGTATGTGTGTTAGTGCTGCACAGGACAATATAACAACAGGCACAGCGATTGTGAGTCAGACAAAGACACAAATGGACTAAAATGGGAAGCAGACAAAGAGGAAAAACAGGGAAATGTCGAGACGACTGGTT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa29094

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000077251	Essential Splice Site	347	937	7	20
ENSDART00000132184	Essential Splice Site	134	690	2	13
ENSDART00000138075	None	None	88	None	4
ENSDART00000138511	None	None	115	None	4
ENSDART00000140357	None	None	140	None	2
ENSDART00000145288	Essential Splice Site	134	753	2	16

The following transcripts of ENSDARG00000054978 do not overlap with this mutation:

ENSDART00000145063

Genomic Location (Zv9):

Chromosome 18 (position 43988300)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	18	45577355
GRCz11	18	45574309

KASP Assay ID:

2261-2591.1 (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GTGACGACGAGGACACACTGCGTCGACACACTACAGTGCCACAGGTCAAG[G/A]TGACATAATAATGATATTGATAGTCATTTCAAAGCCTGTGCATTATAGAG

Long Flanking Sequence:

CCACTAAGAGCAGTAGTTCCCAATCTGGGAGTCACGACCCCCACTAGTGATCCACAAAGATTTATAATGGGTCACTACAGTTTAAGGGTCAGACGTTCAAATTAAACAGATACCAATTTGATGTTAAAATAAGTTGCCAGTTTATTTAGCGATTGTATTAACCTTTGTGCGCATAAAGCTGTAGCAATAGTATGGTGTTTTTTGTTCTCTGTGTGTGTCAGGATGTTGAGGTCCTGCGGGGAGAGCTGTGCCGTAAGGATGAGCAGTGGCGTGAGCGCGAGCGGCGTCTGGCTGCGCTGGAGATGCAGCTGCAGGACAGGAGTGCTGTAGTAGAGGAGCTTCAGCAGCAGCTGGAGGAGGCGGCGCAGCGCAGACATGAGCTCCAGGAGCAGCTGGAGGAAGCATCAGGACACCGAAGCCTAAACGACGAGCAGCTGAACACACGGCTCTGTGACGACGAGGACACACTGCGTCGACACACTACAGTGCCACAGGTCAAG[G/A]TGACATAATAATGATATTGATAGTCATTTCAAAGCCTGTGCATTATAGAGGCTGTATTAGTCACAAATGTCATGAGGATGTCTTAAAGTGCGTGTGAAATCCAAATTTACAATGTTTATTGTGCTAGCACACATTGTTAATCTTTAATTAACAATTAATTCATGCTAAAAAAGTTAGGTTAGTCCACTGGGGGTAAAAGGTTGTTTTGGTAATTTTCAATCAAAGTCTAAGCATTTTGCTTCTTGTTTGAAGTGGCGATTCTTCTCCTTTTTTTTTGCACAGGCAAAAGGGTTAAAAAGTCTAAATGGTTAATGCTGGCAACTTATGATCAACAGTAAAAAAATACCCAGCAGGGAAAACGAGCAACAATGAAGAATGCATCATTATAAGGCAATGGAATCAAAAAATGTCATTATAATATAAGTCAATGAGGCAAAAACAGCCCTGAAAATAACCAAAGATTAGTTAATATGACCAAAATGTATTGAATTTTTGACAAT

Associated Phenotype:

Not determined