Busch Lab

ZMP

brip1

Ensembl ID:
ENSDARG00000074410
ZFIN ID:
ZDB-GENE-081107-11
Description:
BRCA1 interacting protein C-terminal helicase 1 [Source:RefSeq peptide;Acc:NP_001103766]
Human Orthologue:
BRIP1
Human Description:
BRCA1 interacting protein C-terminal helicase 1 [Source:HGNC Symbol;Acc:20473]
Mouse Orthologue:
Brip1
Mouse Description:
BRCA1 interacting protein C-terminal helicase 1 Gene [Source:MGI Symbol;Acc:MGI:2442836]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa17274 Essential Splice Site Available for shipment Available now
sa22659 Nonsense Available for shipment Available now
sa6381 Nonsense Mutation detected in F1 DNA Not yet available
sa35900 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa17274
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109262 Essential Splice Site 178 1216 5 20
ENSDART00000112643 Essential Splice Site 178 1216 4 19
Genomic Location (Zv9):
Chromosome 15 (position 26863360)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 27581596
GRCz11 15 27514472
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTTAAGAATGACAGGAAGCGTATTCGTACACCAGGCACAGAGCAGAAGG[T/C]ACAGCAAYAAATATCTTCTATTTCTGYGACATTATTGGCTTGTTGAGTCT
Long Flanking Sequence:
AATAGCTTCAGACTGAAACTTTTGTTGTTAGATGAGTCAGAATGACAAACATGATAACGTGTTACATCACAAATATATTTGCTTTAGAGTATATGGATTGTGTTTTACATTACATTTCTTTAAATTGAGACTTTTTACACTTTGTGTCCTGTTACTGGGTTAGAGTCCAAGGCTTTATACTGATTTTTATTCACTACCCTTGTATAGATGTGAGCAAACCGTACCAATTTTTACAAAATCATATTGCGTGTCTGAAAAAGCAAGAAGGGTTTACTGCATTAGAATTACAGCAGTATGAGTTAATGCTGACATTTTGGGTTATTTATTATTCTCTTATGTATGCATCCTTGTTAAATTAGGCAAAAGTGACCAACATAAAAAGCCCAGTTTGTCCTCCCGTCTCTCTGAAAAACTTCAAGCCTCGCTTAACAATGGAGAGCATGATGATGATTTTAAGAATGACAGGAAGCGTATTCGTACACCAGGCACAGAGCAGAAGG[T/C]ACAGCAACAAATATCTTCTATTTCTGTGACATTATTGGCTTGTTGAGTCTTGTCTAAACCCTTTTTTCTTTTTTCTGCAGATCAGCAAGCGAAGATGTCTTGAGAAAGGAGTGATTTACATTGACGACGACGATGAAGAAGAGGAGAGTTTGGAGAGACCAGTGCCTGGGGCTCAGACTTGGACCATGGAATTGAACAACGGAGCCAGAGCTGACAGTTGCCAGTCGCAGCCGCAGTGTTGTGTGAGTGCACCACCTCAGACACATTTTCTACTCTTATCTCTAATTTGAAGAATATGATGTAATAAAGTGTCAAAATAGCCATGAAGTGCCCTGTTTGATGTTTCTCGGCATTGCATCATCCAATATCCGTTTAAAGGATTTTTCATCCAAAAATGAAACGTCTGGCATCATGAAGCCTCATGTAGTTCTAAAGCACTATGTTAGTGTTCTGTGGAACACAAGAACATATTGTGAACAATGTTAATACCCTGGCAGAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22659
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109262 Nonsense 419 1216 9 20
ENSDART00000112643 Nonsense 419 1216 8 19
Genomic Location (Zv9):
Chromosome 15 (position 26843341)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 27561577
GRCz11 15 27494453
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCCGTTCCTCTGCCAGATGGAAATCAATTTGAAGGAGCAGATTGTGGTGT[T/A]GGACGAAGCTCATAACATCGAGGACTGTGCCCGTGAGAGTGCTAGTTTCA
Long Flanking Sequence:
ACAGTCGTTTTTTATGTTAGCAGAGTAGCTGCATATAATCAAAGTAAGATATTTGAAAAAAATTAGGTGATTTTCTACAAACGAAGCATGAGCATCTTTTTGTATCTTATTTGTATCTTATAAACACAATCAAGCCTTAAAATTACACTCTGACCACCCCTTTAAATATTACAATTAATATTACAATTACTTTCAATTTTAATATTTTTTGACAATATTGACATTTTACTACATGTGATATTATCAGATAACGTCAGTAGAAAGAAGAAAAATCCATATTCTTATCTCATTGCAGTGATAGAGATTGACTTGTAGAATGTCTTACTTTTGGACATAGTCCAACCTTGTTTTAAAGTATTTCGTTAAAGTCTTCAAATAAGATTAAAGACACATGGTAAGATGTTTTAAGGATTTTTATATAGTATGCTCCCATCTGTTGATAACTGTCGTGCCGTTCCTCTGCCAGATGGAAATCAATTTGAAGGAGCAGATTGTGGTGT[T/A]GGACGAAGCTCATAACATCGAGGACTGTGCCCGTGAGAGTGCTAGTTTCACCCTGAACCAAGCTCAGCTGTTGCTGGCACGTGATGAGATCGATGGAATGGTGACACACAACATTCGGCGTGATCAACACAGGCCTCTGTTGGCCTTCTGTTGCAGCCTCACCAAGTATGAACACTTTTTTTACTCAATGTTTTACATTGTATGAAGTGTGGCATTTATAATGTGATTTATCATAAATATTTCACGGATCAGCTTTCTCATGCCAATCTGAAATTAGTGTTTAATAGGGATTATTTTACTGTATAAATGACATGTGGTTAAAAGAATGGGCTGAATGTCTTGATAATAATTAATATGACATAAATCCTAGTTTAATGAGTGTTTTTATAACTTATTTTAAATGTGACCAAGGTATTTTTATCAGGCTTCTTTTATATGATAACAATTTTAGCATGTGGATATTTCTTCAAATAATTAGTTACTTAGAATTAAATAATAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6381
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109262 Nonsense 707 1216 14 20
ENSDART00000112643 Nonsense 707 1216 13 19
Genomic Location (Zv9):
Chromosome 15 (position 26837578)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 27555814
GRCz11 15 27488690
KASP Assay ID:
554-4785.1 (used for ordering genotyping assays)
KASP Sequence:
CACATTTCAGCATGCAGAGACATTTGCTTTYCAGGATGAAGTAGGAGCCT[T/A]GCTGTTGAAAGTGTGCCATACAGTGAGTCGAGGGGTYCTRTGCTTCCTGC
Long Flanking Sequence:
CTTGTTAACTAACAGCTTGTAAGTTATCTGTTGGCTATCTATGAGGCACAGTTATAAGTAATGAACAAACTATTAACTTTTATTTAACAAGCCATTTTTAACCCATTTACTAACAGTTTATTAATGATCTATTAACTAGTTATAACGGATAGTTATTCTAAAGTGTTACCAACCTAAATGTTTGTTAAGTGTTTTTTTAATGAAGAACATTATTTAAAAACACGTTGTTTTATTCTCTACATTGACTTTATTTGTCTTCACTGTATGATATATATATATATATATATATATATATATATATATATATATATTTTTTTTTTTATGTTAATGACTTCAACATTTGAACAGTAGAATCAATTGTTAAATTCTGTCTTCTATAATATTTGTGTCTATGTCACAGGTCTGGGTTGGTACTATTGGTGCAGGGCCTCAGGGTCGTAAACTTTGCGCCACATTTCAGCATGCAGAGACATTTGCTTTCCAGGATGAAGTAGGAGCCT[T/A]GCTGTTGAAAGTGTGCCATACAGTGAGTCGAGGGGTCCTATGCTTCCTGCCATCTTACAAGGTACACACAAGTCAAGTTGCACTTAATTTTCATTCCTTTACATGTGTGGATATACACTGCAGTGAAATGTTGTGTCTCGCGGGACCCCAGTGCTAAAAAAATAAACATCATCATAAATGTTAAATCAACACTGGAGCTATATTATACCTATATATATATTAGCACTGGAGCCATATTATACCTATATTAAAGCTATATCAAACCTAAACATAACTAACGCACCGGAGCAATAGTCTGTTATATATATAATATAGGTATACAGTGCATCTAGAAAGTATTCCTAGCACTTCACTTTTTCCACATTTTTTAATGTTACAGCCTAATTACCAAATTTATTAAATTTATTTATTTCCTCAAAATTCTACACACAATAACCCATAAAGACAAAAAGATTATTTTTTTAATTGTTGCAAATTTATTACAATTAAAAAAGCTGAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35900
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109262 Essential Splice Site 785 1216 16 20
ENSDART00000112643 Essential Splice Site 785 1216 15 19
Genomic Location (Zv9):
Chromosome 15 (position 26818915)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 27537151
GRCz11 15 27470027
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGTGTTTAAATGTATTGTCTCTGTGTGTTGAGTATGATATATTTTCATA[G/T]ATGGAGCGCTCCTGGTAGCTGTTTGCAGAGGGAAGGTGAGCGAGGGCTTG
Long Flanking Sequence:
TTTGCATTCCAGAATTTGGATTCCATTATGTTTGTTATTAAAAGCATCCCTATTTACCATGCTTGCATCTCCATAAATTACTGATGTATTAAATCATAATTAAAATAAAATCGATTTATAGATCTGGCTTGCTTATTTTTATAGACTAAATACTTTATCCTAATATATTTACTAATAAACGTTATATGCTAAAACATTTTCAGGTGGCTGCATTGCAAGTGATGTTTTAGTCTGTCAAATGTTTTTATTTGATAAGATGTTGGATAAACTGCGGGACCGATGGACGAACACGGGTCTGTGGGATAAGCTTGAGGAGTGCAAGACTGTGATTACCGAGCCCCGTGGTGGTGGCAAGGGTGACTTTGATGAGCTGTTGCAGACATACTATGAGGCAATTAGAGGAACGGCAGCCAAGGGTGAAAAAAGAGGTTAGTGTTGATTTGACACAATTGGTGTTTAAATGTATTGTCTCTGTGTGTTGAGTATGATATATTTTCATA[G/T]ATGGAGCGCTCCTGGTAGCTGTTTGCAGAGGGAAGGTGAGCGAGGGCTTGGACTTCACAGATGACAATGCCAGAGCTGTGGTTACCATTGGTATCCCGTTCCCTAATATTAAGGATTTGCAGGTAACAGGGCAGCAAAGTGGGACATTATGGCCATAACAAAAAACACAATTAATTTGCAAAAAACAGTAAACATTTAACTAAAAAAATCCAGTTGAGATGAAAGTATCTAAATGTTAAATATATCACACCTGTTTAATGATAAAATGTTACATTTTAAAAACAGTTGAACATGTTTTTAAAATGTTGTTCACACATTCATTGTTATACAACCCCTAATCAGAAAAGGTTGGGACAGTATGCAAAACTCAAATTAAAAACAAAGTAGTGATTTCCAAATTTAATTTGACTTATATTTTATTGCAGACAACATAAAATATTTCATGTTTTGTCTGGTCAACTTTATTTCTTTTGTTAATACATATTCTTTCCAGTCATTCA
Associated Phenotype:
Not determined