Busch Lab

ZMP

tmem57b

Ensembl ID:
ENSDARG00000012741
ZFIN ID:
ZDB-GENE-040426-1188
Description:
macoilin [Source:RefSeq peptide;Acc:NP_956757]
Human Orthologue:
TMEM57
Human Description:
transmembrane protein 57 [Source:HGNC Symbol;Acc:25572]
Mouse Orthologue:
Tmem57
Mouse Description:
transmembrane protein 57 Gene [Source:MGI Symbol;Acc:MGI:1913396]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa22376 Essential Splice Site, Missense Available for shipment Available now
sa6330 Nonsense Mutation detected in F1 DNA Not yet available
sa42293 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa22376
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Essential Splice Site, Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000019113 Essential Splice Site 35 214 None 7
ENSDART00000074567 Missense 49 699 2 11
Genomic Location (Zv9):
Chromosome 13 (position 46155633)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 45398541
GRCz11 13 45535445
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAGTTTCTGGTGGTCTGGGCGCTGGTGCTGCTGGCAGACTTTGTGTTGG[A/T]GTTTCGCTTCGAGTACCTCTGGCCTTTCTGGCTCTTTATTCGCAGTGTTT
Long Flanking Sequence:
ATGAAATTCCAGATGTTGCACTCGTTTAATTTACCAACATAATATAAAGAAAAGATTAAGTCTATCGCTGAGGGATAATTACTGTATAATTAAAAATATATATCGTAATCTGCTGGATGTAGTGCACCTTATCTGCATTGCTACATCTGGAGATGGTTTTTACTAAACGTGCTCTTGGCCTACTCTCATCTCTACATAAAACATAATCCACTTGGTTCACTACACGCTGCATTGGAGAAAGCCAAACAGTGATTACGTCCTCCCCCACTGACCCATGCTTCATTGGCTTGGATTTATTGCTGGAGCTCATGATGGAGCTGCTAAATGTTCAGTGGCTCAAGGACATGTGGGTCTTATTCGGAGAGATACTGGATTGAAATGTTGACAAGTGTGATTGAGGTTGAGTTGTAATAAATTGTTATCTGTGTCTTTCAGTACGTTCCTGTATCTGAAGTTTCTGGTGGTCTGGGCGCTGGTGCTGCTGGCAGACTTTGTGTTGG[A/T]GTTTCGCTTCGAGTACCTCTGGCCTTTCTGGCTCTTTATTCGCAGTGTTTACGATTCCTTCAGATACCAGGGCCTGGTGAGTCTCTGTGTGTGGATATGTATGTGTATATATACAGTTGAAGTCTTATGTTGAGGAATTATTAGCCCCACTACAGTGCATCCGGAAAGTATTTATACTGCTTAATCTTTCCACATTTTTTATGTTACAGCCTTATTCCAAAATGAATTAAATTCATTCAAAATTCTACACACAAAAACCCATAATGACAAAGTGAAAAAATATTTTTTTGAAATTGTTGCAAATTTCTTAAAAATAAAAAACCTGAAAAATCACATGCACATCAGTATTTACAGCCTTTGCTCAATACTTTGTTGATGCACCTTTGGCAGCTAGGACTGTGCAATTAATCGAAAATCCGATTTTGATTTTGGCTTGTAACGATTATGAAAAGCCATTAATCGAAATAAACGATTATTCCATCACGTACCGCCCCCTTTCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6330
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000019113 Nonsense 76 214 4 7
ENSDART00000074567 Nonsense 91 699 3 11
Genomic Location (Zv9):
Chromosome 13 (position 46160819)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 45403727
GRCz11 13 45540631
KASP Assay ID:
554-4713.1 (used for ordering genotyping assays)
KASP Sequence:
GCTTTCTCAGTGTTTTTTGTGTGTGTGKCATTCACATCAGATATTATATG[T/A]CTGCTGTTCATCCCAGTACAGTGGCTGTTCTTTGCAGCCAGCACATACGT
Long Flanking Sequence:
TTGCTCTCTTGGACTCTCACACCACCAGAGAGATACATAATTAATAATAATATTACTTTTTGTTATATATTAATTATATTATTAATAATATTAAAAAGATTTTACCGCTGTTGTTTTAATCAGAAAATAAGATGTGATTGCGCTAATTTTTACATTTGTTTTTATTGTAATTTAATGCCTTTTGGACTTGCATGAAATAAGCATTATATGGTTTGGTTACATTTTTCTCTTTTTACTTCATTTGCATATTTTTAATGTTGTGTAATTTGTTCCCCACGGTATCCAAAATGGTATCAAATTCCGATATTTTTTTTAAAGATATCGAAGTTGTAAATTTCAGTATCGTGACAACACTAGTTCACCCAAATGCTTTTTTATGTACACTGTTTACTGTAAACATCTTGCTAGTTGCACATCTGATGATCGGATGCATCTCTCTGTGTGTTTCAGGCTTTCTCAGTGTTTTTTGTGTGTGTGGCATTCACATCAGATATTATATG[T/A]CTGCTGTTCATCCCAGTACAGTGGCTGTTCTTTGCAGCCAGCACATACGTGTGGGTACAGTACGTCTGGCACACAGGTAAGAGTTTCACATCACTCGTTATAGCAGTTATTAGTAGGGCTGCAGGAATATTGGATACATTTCATTTTTTCGCGATATGAACACAGCTTCACAAGATAGTTTGAAGAGCTGTATTTGACAGCTTTCTGGGGAGTCTAACAGTATTTGGGTACAGAAACCAAATATCAATGAAAAAAAATATTTTTTTTACTTTGCTTCGATTCAAGTCCAAATATCTACAAATTCTGAGATCAAGTAGTTTTATTTTCACCTTCAGAAGAAATAAGTCACAATTAAGAGCTTTTAGTTTTTCTTTAGAACAAGCAAAATGATTTGCCAATGGGATTAGCAAAATAATATTATTTTCACTTTGAAATGTAGATTTGGATCAAGACAAAATATTATAAGTAAAAAATTTTTTTTTTGCATAAACAGTAAACAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42293
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000019113 None None 214 None 7
ENSDART00000074567 Nonsense 433 699 7 11
Genomic Location (Zv9):
Chromosome 13 (position 46185477)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 45428385
GRCz11 13 45565289
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGTGTGTGTCAGGCTGGAGCAGGATGTTAAGAAGCTGAAGGCAGATCTG[C/T]AGGCCAGCAGACAGACCGAACAGGATCTGCGCAGTCAGCTGGGCTCTCTG
Long Flanking Sequence:
TCGGAGTGTAGCCTTAATATAGGCAAATGGTAGTTATTATGACAAGAGACTCAGTTGTTGTTATTTTTAGTTGCTTTAATAGTGTGGACCACAATTTTCTTTTTGATCCTCACAATTTTGGAATCCAGTCGCGAGCCGGATTGAACGACTCAGCGGGCCGGATTTGGCCCGCGAGCCGCCAGTTGATGATCAGTGCTCTATAGTATCTGACATGCCCCGTCCACTTCTTCTCATTTGCTTTTCATTTGATGCTCTTGAGCTCAACCGCTTTCACTGACGCTATTGGCTGTTTTTTTTTTTAAAGGGGAGGAGCTACTCTCTGTCCCACCCTCTCTTTGTGTTTCAGTTGAGATTGCGTCAAACATCTAATAAAAAAAGCACATTTCAAAGCACTTCACTGGACCTTTGTTATAAATAACCTCTTCATGACCAGAATGTTGTTGTATGTGTGTGTGTGTGTCAGGCTGGAGCAGGATGTTAAGAAGCTGAAGGCAGATCTG[C/T]AGGCCAGCAGACAGACCGAACAGGATCTGCGCAGTCAGCTGGGCTCTCTGGGCACCTCCGAACGCAGCATACGCTCCGAACTCGGCCAGCTGCGGCAGGAAAACGAACTACTGCAAAACAAGTGAGACTCCCATTCTTCACCATAACATATAACCCAATGCAGTGCTCTAGCTGTGTTAATGCGAATTCTTTGTGTGCACGTTCAGACTTCATAACGCCGTTCAGGCAAAGCAGAAAGATAAGCAGACGCTGGGGCAGCTGGAGAAGCGTCTGAAGGCAGAACAGGAGGCTCGAGCCGCAGCAGAGAAACTGTTAGCAGAGGAGAAGAAACGCAAGAAGCTGGAGGAGGCCACGGCGGCCCGCGCTGTCGCTCTCGCTGCTGCAACCAGGTGCTCACACCTTCCCATCATGCCATTGAAAATTAAACAATTTATAGCTTCACCCTCATCCATCAGCAAACTATCACAAAATTCCGCTATTTCCCTCATCATTTCTGTACT
Associated Phenotype:
Not determined