Busch Lab

ZMP

tp53bp2

Ensembl ID:
ENSDARG00000009136
ZFIN ID:
ZDB-GENE-040516-8
Description:
tumor protein p53 binding protein, 2 [Source:RefSeq peptide;Acc:NP_999979]
Human Orthologue:
TP53BP2
Human Description:
tumor protein p53 binding protein, 2 [Source:HGNC Symbol;Acc:12000]
Mouse Orthologue:
Trp53bp2
Mouse Description:
transformation related protein 53 binding protein 2 Gene [Source:MGI Symbol;Acc:MGI:2138319]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa6281 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa19048 Nonsense Mutation detected in F1 DNA Not yet available
sa10408 Nonsense Available for shipment Available now
sa35389 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa6281
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000006892 Essential Splice Site 266 1060 8 18
Genomic Location (Zv9):
Chromosome 13 (position 525823)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 523806
GRCz11 13 654097
KASP Assay ID:
554-4729.1 (used for ordering genotyping assays)
KASP Sequence:
TCAGMCATATTGCCAGCCCTACTCCACAGATYACCTGTGTTTGTTCATCA[G/A]ATGCGGAAAAACCTGAACGTGGAGCAGAACGCTAAACTGCAGCAGCARCG
Long Flanking Sequence:
CATCCAGCTCGGTGAGCTTATAAACTCCTCCAGAAACTGAACCTGGATGACGGAGGCTTTCAGCGGTGCTTCTGACTGAGCCCAGCCCAGTTTGATGAACTTTTTGTTGGTGTCAGCTGGAGGATTTCCCCCGGGACACCGACAACAGGCGATACGTCACAATCACGCCACCACAAGAGCAAGCTCCTGATTGGTTAACGTGGCGCGAATGTCCGCTAAAGTTCAGATTTTCAAACTCCAGCAATTGTTAAGCGCGTCAAACGCTCAATTCACGCATATCGCGGCATTCGCACAGCGGCATTCGTACATATCGTGCCGCAGGATCTCTATTCATGTGTTTGCATTGACTTAACATGTAAATCACTCGCGCTTGACGTGCGTTCCGCGTCTGGTGTGGACGCAGCATTATAATTTTGCTTCTATTTAAGAAGGAAATATGAATGTAGGTTTTCAGACATATTGCCAGCCCTACTCCACAGATCACCTGTGTTTGTTCATCA[G/A]ATGCGGAAAAACCTGAACGTGGAGCAGAACGCTAAACTGCAGCAGCAGCGCGAGAACCTGAACAAGAGGAACCAGGAGGTGGCTAACATGGACAAACGTGTCAGTGAGCTGCGCGAGCGCTTGTGGAAGAAGAAAGCTGCTCTACAGCAGAAGGAGAACCTTCCTGTGAGTGCTTACAGTCGGATGTTTTGGCTTGAGGGCCTCACTGCCCTATCTTCTAAGGTTTATCAGCAGCCGTTTTATATCCCTGAAGGGTTTATTCTGCAATCATAACCAGCTGGATGTACATTATCCTGGTTATTAGATGGCTACTAGCCACAAACATTATATATGACTGTTAGTAAATTTTACCTTTATTTTTACCTTTAAATGTATTTGTTTGTGTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAGTTTTATCTATTTCTCAGTGAATATAGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19048
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000006892 Nonsense 781 1060 13 18
ENSDART00000006892 Nonsense 781 1060 13 18
Genomic Location (Zv9):
Chromosome 13 (position 530689)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 528672
GRCz11 13 658963
KASP Assay ID:
2260-5864.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTCCTCATCCGGCCCCGAAAATTGACGCATCCATTATCATCCCACCGCCA[C/T]AGCCGGAGAGCCCTCCACCTCCACCTCCTCCTGACAGCTTCATGGAGGAT
Long Flanking Sequence:
ACCCATACTTGGACCCCCCCAGTGTCTCCGAAACCCTTACCGACCACAGTCCTGCAGAGCCCATTTCAGAAACCCCAGAAACAGAGCGCATTCCCAGACCCCTCAGTCCCACCAAACTGCTGCCCTTCATCTCGAACCCTTACCGCCACCAGAGTGACCTGGACCTGGAGGCGCTTCGGAAGAAACTCTACAACGCCCCACGGCCCCTTAAGAAACGCAGCTCCATCACAGAGCCTGAGGGCCCAGGCGGCCCCAACATCCAGAAACTGTTGTATCAGAAGACCACTCTGGCGGCGATGGAGACGGTAAGTCCTCCTGGAGAGGAGGAGAAGGAGACGCTAGCGAAACCGCAGGGATACGATGCAGAAACCCCAGAAGTGCCTGAAGAAACACTTCCCGAATTTCCAATCGCTCCTGAAGTGGAAGCAGAAGACGTTCCTCCGCCGCCACCTCCTCATCCGGCCCCGAAAATTGACGCATCCATTATCATCCCACCGCCA[C/T]AGCCGGAGAGCCCTCCACCTCCACCTCCTCCTGACAGCTTCATGGAGGATTTCCCGCCGTATCCTCCACCTCCGTATCCAAGCAGTGCCGAGCAGGACAATCCAGACGACACCTTCAACATGAAGCCACCAGAGGTCACAGGACAGGTTCCCTTCCCACCTGTAAGAACTTAAATTTGTTTAACAGTAGACGGCGCTCTGGACTAGTTTATAACACTAGATGGCGCTGTAGACTAGTGCTTGATAGTGCTCTAGGCTAGTTTATAATAGTAGACATTGCTTTAGGCTAGTTTATAACAGTAGATGGCGCTGTAGACTTGTGCTTGGTGGTGCTCTAGGCTAGTGTTTAACAGTTGACGGCGCTCAAGGCTAATTTATAACAGTAGATGGCACTGTAAACTAGTGCTTGATAGTGCTCTAGCTTAATATTTAACAGTAGATGGTGCTCTAGGCTAATTTTTAACAGTAGATAGCGCTGTAGACTTGTGCTTGATGGTGCTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10408
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000006892 Nonsense 781 1060 13 18
ENSDART00000006892 Nonsense 781 1060 13 18
Genomic Location (Zv9):
Chromosome 13 (position 530689)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 528672
GRCz11 13 658963
KASP Assay ID:
2260-5864.1 (used for ordering genotyping assays)
KASP Sequence:
CTCCTCAYCCGGCCCCRAAAATTGACGCATCCATTATCATCCCACCGCCA[C/T]AGCCGGAGAGCCCTCCACCTCCACCTCCTCCTGACAGCTTCATGGAGGAT
Long Flanking Sequence:
ACCCATACTTGGACCCCCCCAGTGTCTCCGAAACCCTTACCGACCACAGTCCTGCAGAGCCCATTTCAGAAACCCCAGAAACAGAGCGCATTCCCAGACCCCTCAGTCCCACCAAACTGCTGCCCTTCATCTCGAACCCTTACCGCCACCAGAGTGACCTGGACCTGGAGGCGCTTCGGAAGAAACTCTACAACGCCCCACGGCCCCTTAAGAAACGCAGCTCCATCACAGAGCCTGAGGGCCCAGGCGGCCCCAACATCCAGAAACTGTTGTATCAGAAGACCACTCTGGCGGCGATGGAGACGGTAAGTCCTCCTGGAGAGGAGGAGAAGGAGACGCTAGCGAAACCGCAGGGATACGATGCAGAAACCCCAGAAGTGCCTGAAGAAACACTTCCCGAATTTCCAATCGCTCCTGAAGTGGAAGCAGAAGACGTTCCTCCGCCGCCACCTCCTCATCCGGCCCCGAAAATTGACGCATCCATTATCATCCCACCGCCA[C/T]AGCCGGAGAGCCCTCCACCTCCACCTCCTCCTGACAGCTTCATGGAGGATTTCCCGCCGTATCCTCCACCTCCGTATCCAAGCAGTGCCGAGCAGGACAATCCAGACGACACCTTCAACATGAAGCCACCAGAGGTCACAGGACAGGTTCCCTTCCCACCTGTAAGAACTTAAATTTGTTTAACAGTAGACGGCGCTCTGGACTAGTTTATAACACTAGATGGCGCTGTAGACTAGTGCTTGATAGTGCTCTAGGCTAGTTTATAATAGTAGACATTGCTTTAGGCTAGTTTATAACAGTAGATGGCGCTGTAGACTTGTGCTTGGTGGTGCTCTAGGCTAGTGTTTAACAGTTGACGGCGCTCAAGGCTAATTTATAACAGTAGATGGCACTGTAAACTAGTGCTTGATAGTGCTCTAGCTTAATATTTAACAGTAGATGGTGCTCTAGGCTAATTTTTAACAGTAGATAGCGCTGTAGACTTGTGCTTGATGGTGCTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35389
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000006892 Nonsense 912 1060 15 18
Genomic Location (Zv9):
Chromosome 13 (position 532241)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 530224
GRCz11 13 660515
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCCATAATGCAGTGTGTGCGGGTCACACAGAGATCGTCAAATTCCTGGTT[C/T]AGTATGGAGTCAACGTGAACGCAGCCGACAGTGACGGATGGTGAGCAGCG
Long Flanking Sequence:
GGCGCTGTAGACTTGTGCTTGATGGTGCTCTAGGCTAATGTTTAACAGAAGATGGTGCTATAGGCTAATTTATAACAGTAGATAGCACTGTAGACTAGTGCTTGATGGCGCTCTAGGCTAGTGTTTAACATCAGATCTCTGTCTGTGTTTGGTGTTCAGGGCAAGAGGACAAACCTGCGTAAATCTGGATCCGAGCGCATCGATCACAGCATGCGGGTGCGCTTCAATCCTCTGGCTCTCTTACTGGACTCGTCGCTGGAGGGAGAGTTTGACCTGGTGCAGAGGGTCATATATGAGGAAAGACTCTTTTCACTGTTTAAACTTCAGTGTCAGAGTGTGTGTGTGAGTGGATATTAGTATGTCATAGACACTAACGACACTGTTCTGATGTTTGTTTGCTTGAACAGGTTGAGGATCCGAGTCAGCCGAATGACGAGGGCATCACTGCGCTCCATAATGCAGTGTGTGCGGGTCACACAGAGATCGTCAAATTCCTGGTT[C/T]AGTATGGAGTCAACGTGAACGCAGCCGACAGTGACGGATGGTGAGCAGCGCCTTAACACACTGCAAAACATACAGGCTGTTTAATCACATGATTCCACTTCAGTAACTAATAGTTAATAAGGTGTCGCATACTTGTGTACTAATCTATGTAGTTTGAATAGTGTAATTTAGTACATTTATGCTGACAAATCTCAAAAGAATAAGTGCCTTTTGAATACCGGGATGATGTACCTATTGGTTCAATACACAGAAGTAGAAAAGGGGAGCAGCTACTGCAGAAACGGAGGAGTTGGTGGTGAAGACGAGGGGCTACTGATGATGAAGGGGTGGAGCTGCCAGTCAAGGGGAGGGGCTGATAATAACGAATGAGGTTTTGATGATGAAGGGGTGTAGCTGGTCATAAAGAATGGGTGGAGCTAATAAACAAGAGGAGGAGCTGATCATAAAGGGGGAGGTTATAATGAAGGGGAGGGGCTTATCATTAAGAAGGGCGGTTATAA
Associated Phenotype:
Not determined