Busch Lab

ZMP

im:7158374

Ensembl ID:
ENSDARG00000061844
ZFIN ID:
ZDB-GENE-060810-103
Human Orthologue:
ARHGEF15
Human Description:
Rho guanine nucleotide exchange factor (GEF) 15 [Source:HGNC Symbol;Acc:15590]
Mouse Orthologue:
Arhgef15
Mouse Description:
Rho guanine nucleotide exchange factor (GEF) 15 Gene [Source:MGI Symbol;Acc:MGI:3045246]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa35285 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa6251 Nonsense Mutation detected in F1 DNA Not yet available
sa22088 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa35285
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000088470 Essential Splice Site 766 937 11 15
Genomic Location (Zv9):
Chromosome 12 (position 23722629)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 22245791
GRCz11 12 22367010
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTCTACCTCTTTCTTTTCAATGACCTACTTGTCATTGCCATCAAGAAAAG[G/A]TAAAATGCTGGAAAAACCTGTCTGTGTTATGCTTCACTTTGTTTCTTTCA
Long Flanking Sequence:
TATTTTTTATGAATTTTCGTTTTTGGGTGAACTATCCCTTAAAATGATATGCAATTGACGTAGTAAATTCTACAGGGAGTTATTTAATTGTCTTGTTGCACTTTTTAAAAGTGTTACTTTTGACAAATTCATCTTGATAAATAAAATGTGTTTTATTTAAAAAAAAAAAATTTTGAAAGCTTTTGAATGTTGACATACATATAACTATTTTATTAAAAAACCCAAATCCACAAAAAAAATCAAACAAACATTTTGGAGATTTGATTGTATTACAAATGCATTATATGTTTATGTGTATTAGTTGAAATATTGTCTCATCATTGATATATATCATATATTCAGGCAGTGCCAATTATATCTCAAACACGTTATTTGGAGAAACAAGGAGAGGTGCTGGAAGTAAATAAAGGAGGAACGTTCTTGGGCAACCTGCGCCCCAAATTTACCCCCGTCTACCTCTTTCTTTTCAATGACCTACTTGTCATTGCCATCAAGAAAAG[G/A]TAAAATGCTGGAAAAACCTGTCTGTGTTATGCTTCACTTTGTTTCTTTCATCTTGGTCTAAGCAAATTCTTGAGCATACATCAAGTTTATGTGTGCAGTGCACTCCACTAATATTTTGGTAAATATTTGTAATACAAAATGCCTTTAATTAACTTTTGCAGAAAATATAAACAAAATAGCTCTACTTTCATCAAGAGTAAACAAATGGCAGCACAGCGCACTATCAAAAAGAAAGGTCACACTTTATTTTGATGGTCCGTTTGTTGAATGAAGTTACATTGCATCTACATGCCAACTATGTAGACTGTTAGGTTGTGGTTAGGGTTGGGGTCAGGGTTAGGGTTAGTGTAAGTTGACATGTACTTGCAACGTTTTTATAGTCGGTTAAATGTCTGTTGAAGGAGCAGTATCAATAAATATTAAGCAGACAGTCTACTAATACTCAACTGGACCATCAAAATAAAGTGTTAACAAAAGAAAACATCTTTGTTAAAAAAATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6251
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000088470 Nonsense 809 937 12 15
Genomic Location (Zv9):
Chromosome 12 (position 23721475)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 22244637
GRCz11 12 22365856
KASP Assay ID:
554-4547.1 (used for ordering genotyping assays)
KASP Sequence:
CCAACATAGAGCACTGCTTCTGTCTGACGCTGCTGGAGAATCACCAGGGA[C/T]GACAGATGGAGAGAATCATGAAGGCTCCCTCACAGTGCGTGAAGTTATAA
Long Flanking Sequence:
GGAAATATATAGGCAAAACTCCCTCAGGCATTCATCACACATGAGTAAGAGCACAAAAAAAATCATGTAGAGCTTCACAAAAACCAAAGGGGTTATTAGAAAAAAGGCTAAAACACTGAAAATGTTTCTAAAACTTCTGAAATCTTCCGTCATCAATCATCATCAGTTTTATTAAATTCATATTTTGAGCAAAAGATTAAAAGGTTAACCAATAAAGACCAAGTCGAGGTCCAATATTAGCGGAGGGCACTGTAATACTTTATTTATTGTCTATTTCTATAAAAAGTAACACACCTGATTTCATTTAATGGACATTTGGTTTCTGAATGGGACTGTACTAATGTACTTGTGTCTCTGTTTCTGTGTGCTGCAGTGCTGAGCGGTATGTGGTGCTGGATCATGCCCATCGTTCGCTGGTCCAGGTGCAGTCATATGAGAACTCAGCTGTGCCCAACATAGAGCACTGCTTCTGTCTGACGCTGCTGGAGAATCACCAGGGA[C/T]GACAGATGGAGAGAATCATGAAGGCTCCCTCACAGTGCGTGAAGTTATAAATAAACCTACAGTATACTATTCATTTGATTCATCCACTATACATTTTTAGTCTGATAATTTAAGCATGTTTCAAATTTAAATACACTTGTCATTTTATATACAGTGTATTCGGAAAGTACTCATAGCGCTTCACTTTTTCCACCTTTTTTTTGTTACAGCCTTATTCCAAAATTGATTAAAGTGAAAAAAGATTGTTTGTACATAAATATTCACAGCCTTTGTTGTGAAGCTCTAAAATGAGCTCATGTACCTTCTGTTTCCGCTGATCATTCTTGAGATGTTTCAGCAACTTAATTGAAGTTCACCTGTGGTAAATTCAGTTGATTGGACATGATTTGAAAAGGCATACACCTGTCTATATAAGGTCCCAGGGTTGACAGTGCATGTCAAAGCACAAATCAAGCATGAAGACAATGGAATTGTCTGTAGACAATGTGGAAAATGTGAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22088
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000088470 Nonsense 854 937 14 15
Genomic Location (Zv9):
Chromosome 12 (position 23719633)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 22242795
GRCz11 12 22364014
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGTTGCTCTTGAATCACATGTGGTTTTGTATGTCAGATTGTCCTCAGGTG[C/T]AGTGTGTGGAGCAGTATGTGGCAAAACAATCGGATGAATTAAATCTGGAG
Long Flanking Sequence:
AGTATTCTTTTACGACATAGCGCATATGAGATAAATGACATCAGTACGTTATAACAGTTGATGATCTATTAATGAACCGATAGGATTGTCCATGTTTGCATTGCAATGCATTGAAGAAACAATTAATTTAGGATATACATTTTAGGATAAATGGATATGGTAGCTTTATAGAATACATAGGGCCAGGAATATTATACTCAGTCAGGCTGTAAAGATATATGCTGCTTTTAATGATACATAAGTCATGTATCTTTTATCTCACCAATTAGATCTGACTCACAAAGATGGTTGGCAGTGTTTCCAAATCCTGACGACCCCAAAAATGATCAAGAAGAAGTCATATATGAAGACTGGGGTAAGTTTTTGTCCCAGTTGCTGAGGATTTCACTCATGTCCGACATGCTAGTGCTTGACATTGATTTCCATCACATTCTGTTCTCTCTTCCGAAACGTTGCTCTTGAATCACATGTGGTTTTGTATGTCAGATTGTCCTCAGGTG[C/T]AGTGTGTGGAGCAGTATGTGGCAAAACAATCGGATGAATTAAATCTGGAGCGCACAGAGATCATCAATGTTATACGCAAAACCAATGAAGGTGTGTAACGATTCACATTCCCTTCATAAGAAGCACACTGTCAGTTTTGAGATTTAGTGATTTAGTTTTTTCTCTCTAAAGGAAAAAGATACTTTCATACATCATTTGCTTGAATATATTTTATTCTACCAAAAACTGTGGAAAATTTCAGTCATATACAGGGTTCACACAGGTCATGGAATTTCTGCAATAACATGGCGTTTCAAAGTTTCTATTCTAAACACTGAAATTGAGAGAATTATATATATTTTATGTCATGAAAGACGTTGAATTTCAGGAATTTTTTCTGTCATTTCAAGTTTAACTTTTCCATTTATTTATTTATTTTTTTACCAGTTTTGTATTGCGTTGTAATAAAAAACACATAAAGTGTAGTCTATATTAGCTACCATAAATGGTCGCTGACAGAA
Associated Phenotype:
Not determined